| Source: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Type: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Risk: by definition reduces risk of disease or cancer. Down Target direction of risk indicates lower cancer risk. ChemoPreventive also mean lower cancer risk. But for Chemopreventive an up arrow indicates more preventive.
Cancer Risk Impact Score (CRIS)
CRIS scale:
–5 = very strong risk reduction
–4 = strong risk reduction
–3 = moderate risk reduction
–2 = modest risk reduction
–1 = weak / context-dependent
0 = neutral
|
| 5705- | Brut, | A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer, the Pirc rat (F344/NTac-Apcam1137) |
| - | in-vivo, | CRC, | NA |
| 5738- | Buty, | Butyrate’s role in human health and the current progress towards its clinical application to treat gastrointestinal disease |
| - | Review, | Nor, | NA |
| 5731- | Buty, | The Warburg Effect Dictates the Mechanism of Butyrate Mediated Histone Acetylation and Cell Proliferation |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | HT29 |
| 5778- | Calc, | VitD3, | Colorectal cancer risk and dietary intake of calcium, vitamin D, and dairy products: a meta-analysis of 26,335 cases from 60 observational studies |
| - | Study, | CRC, | NA |
| 5777- | Calc, | Calcium intake and colorectal cancer risk: dose-response meta-analysis of prospective observational studies |
| - | Study, | CRC, | NA |
| 5775- | Calc, | Calcium Intake and Risk of Colorectal Cancer in the NIH-AARP Diet and Health Study |
| - | Study, | CRC, | NA |
| 5776- | Calc, | Calcium |
| - | Review, | Var, | NA |
| 5860- | CAP, | Beneficial Effects of Capsaicin in Disorders of the Central Nervous System |
| - | Review, | AD, | NA | - | Review, | Park, | NA | - | Review, | Stroke, | NA |
| 3854- | CAP, | Capsaicin consumption reduces brain amyloid-beta generation and attenuates Alzheimer’s disease-type pathology and cognitive deficits in APP/PS1 mice |
| - | in-vivo, | AD, | NA |
| 3855- | CAP, | Capsaicin consumption reduces brain amyloid-beta generation and attenuates Alzheimer’s disease-type pathology and cognitive deficits in APP/PS1 mice |
| - | in-vivo, | AD, | NA |
| 1265- | CAP, | Capsaicin shapes gut microbiota and pre-metastatic niche to facilitate cancer metastasis to liver |
| - | in-vivo, | CRC, | NA |
| 5932- | CAR, | Carvacrol attenuates mucosal barrier impairment and tumorigenesis by regulating gut microbiome |
| - | in-vivo, | IBD, | NA | - | in-vivo, | Park, | NA |
| 5930- | Catechins, | Randomized, Placebo-Controlled Trial of Green Tea Catechins for Prostate Cancer Prevention |
| - | Trial, | Pca, | NA |
| 5966- | CEL, | Determine whether administering celecoxib during radiotherapy can reduce the risk of recurrence of triple-negative breast cancer. Pilot study |
| - | Trial, | BC, | NA |
| 5955- | CEL, | COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib |
| - | in-vitro, | Colon, | NA |
| 5954- | CEL, | The molecular mechanisms of celecoxib in tumor development |
| - | Review, | Var, | NA |
| 6038- | CGA, | Neuromodulation and neuroprotective effects of chlorogenic acids in excitatory synapses of mouse hippocampal slices |
| - | in-vivo, | AD, | NA | - | in-vivo, | Stroke, | NA |
| 6041- | CGA, | Effect of Chlorogenic Acid Intake on Cognitive Function in the Elderly: A Pilot Study |
| - | Trial, | AD, | NA |
| 6035- | CGA, | Effect of Chlorogenic Acids on Cognitive Function in Mild Cognitive Impairment: A Randomized Controlled Crossover Trial |
| - | Trial, | Nor, | NA |
| 6087- | CHOC, | Effect of cocoa flavanol supplementation for the prevention of cardiovascular disease events: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial |
| - | Trial, | Nor, | NA |
| 6091- | CHOC, | Chocolate Consumption in Relation to All-Cause and Cause-Specific Mortality in Women: The Women's Health Initiative |
| - | Study, | Nor, | NA |
| 6084- | CHOC, | Cocoa Polyphenols and Their Potential Benefits for Human Health |
| - | Review, | Nor, | NA | - | Review, | Stroke, | NA | - | Review, | IBD, | NA |
| 6102- | Chol, | Higher dietary choline intake is associated with increased risk of all-cause and cause-specific mortality: A systematic review and dose-response meta-analysis of cohort studies |
| - | Analysis, | CardioV, | NA |
| 6104- | Chol, | Dietary choline intake and colorectal cancer: a cross-sectional study of 2005–2018 NHANES cycles |
| - | Study, | HCC, | NA |
| 6097- | Chol, | Choline intake and risk of lethal prostate cancer: incidence and survival |
| - | Study, | Pca, | NA |
| 6096- | Chol, | Plasma methionine, choline, betaine, and dimethylglycine in relation to colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) |
| - | Study, | CRC, | NA |
| 4766- | CoQ10, | Activities of Vitamin Q10in Animal Models and a Serious Deficiency in Patients with Cancer |
| - | Review, | Var, | NA |
| 4768- | CoQ10, | Role of coenzymes in cancer metabolism |
| - | Review, | Var, | NA |
| 4769- | CoQ10, | CoQ10 Is Key for Cellular Energy and Cancer Support |
| - | Review, | Var, | NA |
| 4770- | CoQ10, | VitK2, | Cancer cell stiffening via CoQ10 and UBIAD1 regulates ECM signaling and ferroptosis in breast cancer |
| - | in-vitro, | BC, | MDA-MB-231 |
| 2152- | dietFMD, | Prolonged Nightly Fasting and Breast Cancer Prognosis |
| - | Analysis, | BC, | NA |
| 1844- | dietFMD, | Unlocking the Potential: Caloric Restriction, Caloric Restriction Mimetics, and Their Impact on Cancer Prevention and Treatment |
| - | Review, | NA, | NA |
| 2162- | dietP, | Effect of low-fat diet on breast cancer survival: a meta-analysis |
| - | Analysis, | BC, | NA |
| 2160- | dietP, | Dietary proteins and protein sources and risk of death: the Kuopio Ischaemic Heart Disease Risk Factor Study |
| - | Trial, | Heart, | NA |
| 2159- | dietP, | Postdiagnostic Fruit and Vegetable Consumption and Breast Cancer Survival: Prospective Analyses in the Nurses' Health Studies |
| - | Human, | BC, | NA |
| 2158- | dietP, | Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality in a Japanese Cohort |
| - | Human, | Nor, | NA |
| 2157- | dietP, | Plant-Based Diets and Disease Progression in Men With Prostate Cancer |
| - | Study, | Pca, | NA |
| 5065- | dietSTF, | dietFMD, | Nutrition, GH/IGF-I Signaling, and Cancer |
| - | Review, | Var, | NA |
| 5069- | dietSTF, | The Role of Intermittent Fasting in the Activation of Autophagy Processes in the Context of Cancer Diseases |
| - | Review, | Var, | NA |
| 5071- | dietSTF, | Unraveling the impact of intermittent fasting in cancer prevention, mitigation, and treatment: A narrative review |
| - | Review, | Var, | NA | - | Review, | AD, | NA |
| 2143- | Ex, | The association between physical activity and bladder cancer: systematic review and meta-analysis |
| - | Review, | Bladder, | NA |
| 2144- | Ex, | Physical activity, hormone replacement therapy and breast cancer risk: A meta-analysis of prospective studies |
| - | Analysis, | NA, | NA |
| 2145- | Ex, | Leisure time physical activity and cancer risk: evaluation of the WHO's recommendation based on 126 high-quality epidemiological studies |
| - | Analysis, | Var, | NA |
| 2146- | Ex, | A systematic review and meta-analysis of physical activity and endometrial cancer risk |
| - | Review, | Endo, | NA |
| 2147- | Ex, | The association between physical activity and gastroesophageal cancer: systematic review and meta-analysis |
| - | Review, | GC, | NA |
| 4138- | Ex, | Relationship Between Exercise and Alzheimer’s Disease: A Narrative Literature Review |
| - | Review, | AD, | NA |
| 1623- | FA, | Folic acid: friend or foe in cancer therapy |
| - | Review, | Var, | NA |
| 2173- | FA, | VitB12, | Elevated serum homocysteine levels associated with poor recurrence-free and overall survival in patients with colorectal cancer |
| - | Study, | CRC, | NA |
| 4076- | FA, | VitE, | VitB6, | Reduced risk of Alzheimer’s disease with high folate intake: The Baltimore Longitudinal Study of Aging |
| - | Study, | AD, | NA |
| 4059- | FA, | Dietary B Vitamins and a 10-Year Risk of Dementia in Older Persons |
| - | Study, | AD, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:785 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid