| Source: |
| Type: |
| Cell Viability |
| 1533- | Ba, | Baicalein, as a Prooxidant, Triggers Mitochondrial Apoptosis in MCF-7 Human Breast Cancer Cells Through Mobilization of Intracellular Copper and Reactive Oxygen Species Generation |
| - | in-vitro, | BrCC, | MCF-7 | - | in-vitro, | Nor, | MCF10 |
| 2475- | Ba, | Baicalein triggers ferroptosis in colorectal cancer cells via blocking the JAK2/STAT3/GPX4 axis |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | DLD1 | - | in-vivo, | NA, | NA |
| 5539- | BBM, | Berbamine suppresses cell viability and induces apoptosis in colorectal cancer via activating p53-dependent apoptotic signaling pathway |
| - | vitro+vivo, | CRC, | SW480 |
| 5547- | BBM, | Berbamine exerts anticancer effects on human colon cancer cells via induction of autophagy and apoptosis, inhibition of cell migration and MEK/ERK signalling pathway |
| - | in-vitro, | CRC, | HT29 |
| 5549- | BBM, | Synergistic Anticancer Effect of a Combination of Berbamine and Arcyriaflavin A against Glioblastoma Stem-like Cells |
| - | in-vitro, | GBM, | NA |
| 5551- | BBM, | Berbamine Suppresses the Progression of Bladder Cancer by Modulating the ROS/NF-κB Axis |
| - | vitro+vivo, | Bladder, | NA |
| 1386- | BBR, | Berberine-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species generation and mitochondrial-related apoptotic pathway |
| - | in-vitro, | BC, | MCF-7 | - | in-vitro, | BC, | MDA-MB-231 |
| 1396- | BBR, | Berberine induced down-regulation of matrix metalloproteinase-1, -2 and -9 in human gastric cancer cells (SNU-5) in vitro |
| - | in-vitro, | GC, | SNU1041 | - | in-vitro, | GC, | SNU5 |
| 1402- | BBR, | Berberine-induced apoptosis in human glioblastoma T98G cells is mediated by endoplasmic reticulum stress accompanying reactive oxygen species and mitochondrial dysfunction |
| - | in-vitro, | GBM, | T98G |
| 2691- | BBR, | Berberine induces FasL-related apoptosis through p38 activation in KB human oral cancer cells |
| - | in-vitro, | Oral, | KB |
| 2715- | BBR, | Rad, | Berberine Can Amplify Cytotoxic Effect of Radiotherapy by Targeting Cancer Stem Cells |
| - | in-vitro, | BC, | MCF-7 |
| 5181- | BBR, | Cisplatin, | Berberine Improves Chemo-Sensitivity to Cisplatin by Enhancing Cell Apoptosis and Repressing PI3K/AKT/mTOR Signaling Pathway in Gastric Cancer |
| - | in-vitro, | GC, | SGC-7901 | - | in-vitro, | GC, | BGC-823 |
| 5634- | BCA, | Molecular Mechanisms of Biochanin A in AML Cells: Apoptosis Induction and Pathway-Specific Regulation in U937 and THP-1 |
| - | in-vitro, | AML, | U937 | - | in-vitro, | AML, | THP1 |
| 5636- | BCA, | Biochanin A Induces S Phase Arrest and Apoptosis in Lung Cancer Cells |
| - | vitro+vivo, | Lung, | A549 |
| 5638- | BCA, | Investigating the Anticancer Potential of Biochanin A in KB Oral Cancer Cells Through the NFκB Pathway |
| - | in-vitro, | Oral, | NA |
| 5639- | BCA, | Biochanin A Induces Apoptosis in MCF-7 Breast Cancer Cells through Mitochondrial Pathway and Pi3K/AKT Inhibition |
| - | in-vitro, | BC, | NA |
| 2723- | BetA, | Betulinic acid and oleanolic acid modulate CD81 expression and induce apoptosis in triple-negative breast cancer cells through ROS generation |
| - | in-vitro, | BC, | MDA-MB-231 |
| 2734- | BetA, | Betulinic Acid Modulates the Expression of HSPA and Activates Apoptosis in Two Cell Lines of Human Colorectal Cancer |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | SW480 |
| 2726- | BetA, | Betulinic acid induces DNA damage and apoptosis in SiHa cells |
| - | in-vitro, | Cerv, | SiHa |
| 2730- | BetA, | Betulinic acid induces autophagy-dependent apoptosis via Bmi-1/ROS/AMPK-mTOR-ULK1 axis in human bladder cancer cells |
| - | in-vitro, | Bladder, | T24/HTB-9 |
| 2757- | BetA, | Betulinic Acid Inhibits Glioma Progression by Inducing Ferroptosis Through the PI3K/Akt and NRF2/HO-1 Pathways |
| - | in-vitro, | GBM, | U251 |
| 2742- | BetA, | Betulinic acid impairs metastasis and reduces immunosuppressive cells in breast cancer models |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vivo, | BC, | 4T1 | - | in-vitro, | BC, | MCF-7 |
| 2750- | BetA, | GEM, | Betulinic acid, a major therapeutic triterpene of Celastrus orbiculatus Thunb., acts as a chemosensitizer of gemcitabine by promoting Chk1 degradation |
| - | in-vitro, | PC, | Bxpc-3 | - | in-vitro, | Lung, | H1299 |
| 2751- | BetA, | Betulinic acid inhibits proliferation and triggers apoptosis in human breast cancer cells by modulating ER (α/β) and p53 |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | MCF-7 |
| 5515- | BEV, | Biological activity of bevacizumab, a humanized anti-VEGF antibody in vitro. |
| - | Review, | Var, | NA |
| 5481- | BM, | Therapeutic potential of Bacopa monnieri extracts against hepatocellular carcinoma through in-vitro and computational studies |
| - | in-vitro, | HCC, | HepG2 |
| 5477- | BM, | The Aquaporin 1 Inhibitor Bacopaside II Reduces Endothelial Cell Migration and Tubulogenesis and Induces Apoptosis. |
| - | in-vitro, | Var, | NA |
| 5651- | BNL, | Cisplatin, | Natural borneol sensitizes human glioma cells to cisplatin-induced apoptosis by triggering ROS-mediated oxidative damage and regulation of MAPKs and PI3K/AKT pathway |
| - | in-vitro, | GBM, | U251 | - | in-vitro, | GBM, | U87MG |
| 725- | Bor, | Boric acid exert anti-cancer effect in poorly differentiated hepatocellular carcinoma cells via inhibition of AKT signaling pathway |
| - | in-vitro, | HCC, | NA |
| 1424- | Bos, | Boswellia sacra essential oil induces tumor cell-specific apoptosis and suppresses tumor aggressiveness in cultured human breast cancer cells |
| - | in-vitro, | BC, | T47D | - | in-vitro, | BC, | MCF-7 | - | in-vitro, | BC, | MDA-MB-231 |
| 1447- | Bos, | Boswellia carterii n-hexane extract suppresses breast cancer growth via induction of ferroptosis by downregulated GPX4 and upregulated transferrin |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | MCF-7 | - | in-vivo, | BC, | 4T1 | - | in-vitro, | Nor, | MCF10 |
| 5696- | BRU, | The Nrf2 inhibitor brusatol is a potent antitumour agent in an orthotopic mouse model of colorectal cancer |
| - | in-vitro, | CRC, | HCT116 |
| 5697- | BRU, | Brusatol, a Nrf2 Inhibitor Targets STAT3 Signaling Cascade in Head and Neck Squamous Cell Carcinoma |
| - | in-vitro, | HNSCC, | NA |
| 5746- | CA, | Caffeic acid hinders the proliferation and migration through inhibition of IL-6 mediated JAK-STAT-3 signaling axis in human prostate cancer |
| - | in-vitro, | Pca, | PC3 | - | in-vitro, | Pca, | LNCaP |
| 5877- | CA, | Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells |
| - | in-vitro, | CRC, | HCT116 |
| 5866- | CA, | Carnosic acid inhibits STAT3 signaling and induces apoptosis through generation of ROS in human colon cancer HCT116 cells |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | Colon, | SW480 | - | in-vitro, | Colon, | HT29 |
| 5876- | CA, | Carnosic acid, a rosemary phenolic compound, induces apoptosis through reactive oxygen species-mediated p38 activation in human neuroblastoma IMR-32 cells |
| - | in-vitro, | neuroblastoma, | NA |
| 5774- | CA, | CAPE, | Caffeic Acid Versus Caffeic Acid Phenethyl Ester in the Treatment of Breast Cancer MCF-7 Cells: Migration Rate Inhibition |
| - | NA, | BC, | MCF-7 |
| 5841- | CAP, | The red pepper’s spicy ingredient capsaicin activates AMPK in HepG2 cells through CaMKKβ |
| - | in-vitro, | HCC, | HepG2 |
| 5836- | CAP, | In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway |
| - | vitro+vivo, | PC, | AsPC-1 | - | in-vitro, | PC, | Bxpc-3 |
| 5835- | CAP, | Capsaicin and dihydrocapsaicin induce apoptosis in human glioma cells via ROS and Ca2+-mediated mitochondrial pathway |
| - | in-vitro, | GBM, | U251 |
| 5832- | CAP, | Capsaicin induces cell cycle arrest and apoptosis in human KB cancer cells |
| - | in-vitro, | Oral, | KB |
| 5826- | CAP, | Capsaicin induces mitochondrial dysfunction and apoptosis in anaplastic thyroid carcinoma cells via TRPV1-mediated mitochondrial calcium overload |
| - | in-vitro, | Thyroid, | NA |
| 5203- | CAP, | Capsaicin Promotes Apoptosis and Inhibits Cell Migration via the Tumor Necrosis Factor-Alpha (TNFα) and Nuclear Factor Kappa B (NFκB) Signaling Pathway in Oral Cancer Cells |
| - | in-vitro, | OS, | KB |
| 5198- | CAP, | Capsaicin induces apoptosis by generating reactive oxygen species and disrupting mitochondrial transmembrane potential in human colon cancer cell lines |
| - | in-vitro, | CRC, | LoVo | - | in-vitro, | CRC, | Colo320 |
| 5769- | CAPE, | Caffeic Acid Phenethyl Ester Inhibits the Proliferation of HEp2 Cells by Regulating Stat3/Plk1 Pathway and Inducing S Phase Arrest |
| - | in-vitro, | Laryn, | HEp2 |
| 5767- | CAPE, | Caffeic Acid Phenethyl Ester Is a Potential Therapeutic Agent for Oral Cancer |
| - | Review, | Oral, | NA |
| 5754- | CAPE, | Rad, | The radiosensitizing effect of Caffeic Acid Phenethyl Ester in breast cancer is dependent on p53 status |
| - | in-vivo, | BC, | MDA-MB-231 |
| 5885- | CAR, | Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion |
| - | in-vitro, | GBM, | U87MG | - | in-vitro, | Nor, | HEK293 |
| 5884- | CAR, | Carvacrol affects breast cancer cells through TRPM7 mediated cell cycle regulation |
| - | in-vitro, | BC, | BT474 | - | in-vitro, | BC, | MCF-7 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | MDA-MB-453 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
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