| 1372- | Ash, | Withaferin-A Induces Apoptosis in Osteosarcoma U2OS Cell Line via Generation of ROS and Disruption of Mitochondrial Membrane Potential |
| - | in-vitro, | OS, | U2OS |
| 1373- | Ash, | Endoplasmic reticulum stress mediates withaferin A-induced apoptosis in human renal carcinoma cells |
| - | in-vitro, | Kidney, | Caki-1 |
| 1355- | Ash, | Withaferin A-Induced Apoptosis in Human Breast Cancer Cells Is Mediated by Reactive Oxygen Species |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | MCF7 | - | in-vitro, | Nor, | HMEC |
| 1356- | Ash, | Withaferin A induces apoptosis by ROS-dependent mitochondrial dysfunction in human colorectal cancer cells |
| - | in-vitro, | CRC, | HCT116 |
| 1357- | Ash, | Cytotoxicity of withaferin A in glioblastomas involves induction of an oxidative stress-mediated heat shock response while altering Akt/mTOR and MAPK signaling pathways |
| - | in-vitro, | GBM, | U87MG | - | in-vitro, | GBM, | U251 | - | in-vitro, | GBM, | GL26 |
| 1358- | Ash, | Withaferin A: A Dietary Supplement with Promising Potential as an Anti-Tumor Therapeutic for Cancer Treatment - Pharmacology and Mechanisms |
| - | Review, | Var, | NA |
| 1359- | Ash, | Withaferin A Induces ROS-Mediated Paraptosis in Human Breast Cancer Cell-Lines MCF-7 and MDA-MB-231 |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | MDA-MB-231 |
| 1360- | Ash, | immuno, | Withaferin A Increases the Effectiveness of Immune Checkpoint Blocker for the Treatment of Non-Small Cell Lung Cancer |
| - | in-vitro, | Lung, | H1650 | - | in-vitro, | Lung, | A549 | - | in-vitro, | CRC, | HCT116 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vivo, | NA, | NA |
| - | in-vitro, | Liver, | HUH7 | - | in-vivo, | Liver, | HUH7 |
| 1362- | Ash, | GEM, | Synergistic Inhibition of Pancreatic Cancer Cell Growth and Migration by Gemcitabine and Withaferin A |
| - | in-vitro, | PC, | PANC1 | - | in-vitro, | PC, | Hs766t |
| 1363- | Ash, | doxoR, | Withaferin A Synergizes the Therapeutic Effect of Doxorubicin through ROS-Mediated Autophagy in Ovarian Cancer |
| - | in-vitro, | Ovarian, | A2780S | - | in-vitro, | Ovarian, | CaOV3 | - | in-vivo, | NA, | NA |
| 1364- | Ash, | Withaferin a Triggers Apoptosis and DNA Damage in Bladder Cancer J82 Cells through Oxidative Stress |
| - | in-vitro, | Bladder, | J82 |
| 1365- | Ash, | Withaferin A Induces Oxidative Stress-Mediated Apoptosis and DNA Damage in Oral Cancer Cells |
| - | in-vitro, | Oral, | Ca9-22 | - | in-vitro, | Oral, | CAL27 |
| 1367- | Ash, | An anti-cancerous protein fraction from Withania somnifera induces ROS-dependent mitochondria-mediated apoptosis in human MDA-MB-231 breast cancer cells |
| - | in-vitro, | BC, | MDA-MB-231 |
| 1181- | Ash, | Withaferin A inhibits Epithelial to Mesenchymal Transition in Non-Small Cell Lung Cancer Cells |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Lung, | H1299 |
| 1180- | Ash, | Withaferin A Inhibits Liver Cancer Tumorigenesis by Suppressing Aerobic Glycolysis through the p53/IDH1/HIF-1α Signaling Axis |
| - | in-vitro, | Liver, | HepG2 |
| 1179- | Ash, | Withaferin-A Inhibits Colon Cancer Cell Growth by Blocking STAT3 Transcriptional Activity |
| - | in-vitro, | CRC, | HCT116 | - | in-vivo, | NA, | NA |
| 1178- | Ash, | Withaferin A suppresses the expression of vascular endothelial growth factor in Ehrlich ascites tumor cells via Sp1 transcription factor |
| - | in-vitro, | Nor, | HUVECs | - | in-vivo, | NA, | NA |
| 1177- | Ash, | Withaferin A downregulates COX-2/NF-κB signaling and modulates MMP-2/9 in experimental endometriosis |
| - | in-vivo, | EC, | NA |
| 1176- | Ash, | Metabolic Alterations in Mammary Cancer Prevention by Withaferin A in a Clinically Relevant Mouse Model |
| - | in-vivo, | NA, | NA |
| 1174- | Ash, | Withaferin A Suppresses Estrogen Receptor-α Expression in Human Breast Cancer Cells |
| - | in-vitro, | BC, | MCF7 | - | in-vivo, | BC, | MDA-MB-231 | - | in-vitro, | BC, | T47D |
| 1173- | Ash, | Withaferin A inhibits proliferation of human endometrial cancer cells via transforming growth factor-β (TGF-β) signalling |
| - | in-vitro, | EC, | K1 | - | in-vitro, | Nor, | THESCs |
| 1172- | Ash, | Withaferin A Inhibits Fatty Acid Synthesis in Rat Mammary Tumors |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vivo, | NA, | NA |
| 1433- | Ash, | SFN, | A Novel Combination of Withaferin A and Sulforaphane Inhibits Epigenetic Machinery, Cellular Viability and Induces Apoptosis of Breast Cancer Cells |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | MDA-MB-231 |
| 2001- | Ash, | Withania somnifera: from prevention to treatment of cancer |
| - | Review, | Var, | NA |
| 2002- | Ash, | Ancient medicine, modern use: Withania somnifera and its potential role in integrative oncology |
| - | Review, | Var, | NA |
| 2003- | Ash, | Withaferin A Induces Cell Death Selectively in Androgen-Independent Prostate Cancer Cells but Not in Normal Fibroblast Cells |
| - | in-vitro, | Pca, | PC3 | - | in-vitro, | Pca, | DU145 | - | in-vitro, | Nor, | TIG-1 | - | in-vitro, | PC, | LNCaP |
| 4303- | Ash, | Ashwagandha (Withania somnifera)—Current Research on the Health-Promoting Activities: A Narrative Review |
| - | Review, | AD, | NA |
| 5169- | Ash, | The Tumor Inhibitor and Antiangiogenic Agent Withaferin A Targets the Intermediate Filament Protein Vimentin |
| - | in-vitro, | BC, | MCF7 |
| 5170- | Ash, | Withaferin A inhibits NF-kappaB activation by targeting cysteine 179 in IKKβ |
| - | Review, | Var, | NA |
| 5171- | Ash, | The tumor proteasome is a primary target for the natural anticancer compound Withaferin A isolated from "Indian winter cherry" |
| - | vitro+vivo, | Pca, | LNCaP | - | vitro+vivo, | Pca, | PC3 |
| 5172- | Ash, | Withaferin-A suppress AKT induced tumor growth in colorectal cancer cells |
| 5173- | Ash, | 2DG, | Withaferin A inhibits lysosomal activity to block autophagic flux and induces apoptosis via energetic impairment in breast cancer cells |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | MDA-MB-468 | - | in-vitro, | BC, | T47D |
| 5174- | Ash, | Withaferin A is a potent inhibitor of angiogenesis |
| - | in-vitro, | Nor, | HUVECs |
| 5175- | Ash, | Withaferin A Induces Proteasome Inhibition, Endoplasmic Reticulum Stress, the Heat Shock Response and Acquisition of Thermotolerance |
| - | in-vitro, | Cerv, | CCL-102 |
| 4660- | Ash, | Withaferin A Alone and in Combination with Cisplatin Suppresses Growth and Metastasis of Ovarian Cancer by Targeting Putative Cancer Stem Cells |
| - | in-vitro, | Ovarian, | NA |
| 4677- | Ash, | Withaferin A (WFA) inhibits tumor growth and metastasis by targeting ovarian cancer stem cells |
| - | vitro+vivo, | Ovarian, | NA |
| 4678- | Ash, | Identification of Withaferin A as a Potential Candidate for Anti-Cancer Therapy in Non-Small Cell Lung Cancer |
| - | vitro+vivo, | NSCLC, | H1975 |
| 4679- | Ash, | Induced cancer stem-like cells as a model for biological screening and discovery of agents targeting phenotypic traits of cancer stem cell |
| - | in-vitro, | NA, | NA |
| 5384- | AsP, | MEL, | Synergistic Anticancer Effect of Melatonin and Ascorbyl Palmitate Nanoformulation: A Promising Combination for Cancer Therapy |
| - | in-vivo, | Var, | NA |
| 5385- | AsP, | GoldNP, | GEM, | Development of ascorbyl palmitate based hydrophobic gold nanoparticles as a nanocarrier system for gemcitabine delivery |
| - | in-vitro, | BC, | NA |
| 5388- | AsP, | Capacity of Ascorbyl Palmitate to Produce the Ascorbyl Radical in Vitro: an Electron Spin Resonance Investigation |
| - | in-vitro, | Nor, | NA |
| 5389- | AsP, | Tras, | ASCORBYL PALMITATE ENHANCES ANTI-PROLIFERATIVE EFFECT OF TRASTUZUMAB IN HER2-POSITIVE BREAST CANCER CELLS |
| 5391- | AsP, | Research Progress of Ascorbyl Palmitate in Drug Delivery and Cancer Therapy |
| - | Review, | Var, | NA |
| 5387- | AsP, | PacT, | Ascorbyl palmitate-incorporated paclitaxel-loaded composite nanoparticles for synergistic anti-tumoral therapy |
| - | in-vivo, | Melanoma, | B16-F10 |
| 1146- | AsP, | Potential use of nanoformulated ascorbyl palmitate as a promising anticancer agent: First comparative assessment between nano and free forms |
| - | in-vivo, | Nor, | NA |
| 4814- | ASTX, | Chemopreventive and therapeutic efficacy of astaxanthin against cancer: A comprehensive review |
| - | Review, | Var, | NA |
| 4825- | ASTX, | In vivo protective efficacy of astaxanthin against ionizing radiation-induced DNA damage |
| - | in-vivo, | Nor, | NA |
| 4824- | ASTX, | Rad, | Astaxanthin protects the radiation-induced lung injury in C57BL/6 female mice |
| - | in-vivo, | Nor, | NA |
| 4823- | ASTX, | Astaxanthin increases radiosensitivity in esophageal squamous cell carcinoma through inducing apoptosis and G2/M arrest |
| - | in-vitro, | ESCC, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:% State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid