Dose Cancer Research Results

Dose, Dosage: Click to Expand ⟱
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Drug dosage vs efficacy, and actual dosage number of research papers.
Scientific Papers found: Click to Expand⟱
3166- Ash,    Exploring the Multifaceted Therapeutic Potential of Withaferin A and Its Derivatives
- Review, Var, NA
*p‑PPARγ↓, *cardioP↑, *AMPK↑, *BioAv↝, *Half-Life↝, *Half-Life↝, *Dose↑, *chemoPv↑, IL6↓, STAT3↓, ROS↓, OXPHOS↓, PCNA↓, LDH↓, AMPK↑, TumCCA↑, NOTCH3↓, Akt↓, Bcl-2↓, Casp3↑, Apoptosis↑, eff↑, NF-kB↓, CSCs↓, HSP90↓, PI3K↓, FOXO3↑, β-catenin/ZEB1↓, N-cadherin↓, EMT↓, FASN↓, ACLY↓, ROS↑, NRF2↑, HO-1↑, NQO1↑, JNK↑, mTOR↓, neuroP↑, *TNF-α↓, *IL1β↓, *IL6↓, *IL8↓, *IL18↓, RadioS↑, eff↑,
2001- Ash,    Withania somnifera: from prevention to treatment of cancer
- Review, Var, NA
toxicity↓, TumW↓, Dose?, eff↝, Ki-67↓, survivin↓, XIAP↓, PERK↑, p‑RSK↑, CHOP/DDIT3↑, DR5↑, Dose↝, BG↓, DNMTs↓,
5387- AsP,  PacT,    Ascorbyl palmitate-incorporated paclitaxel-loaded composite nanoparticles for synergistic anti-tumoral therapy
- in-vivo, Melanoma, B16-F10
Dose↝, TumCG↓, TumCP↓, BioAv↓, BioAv↑, other↑, Apoptosis↑, Bax:Bcl2↑, EPR↑, toxicity↝,
4819- ASTX,    Astaxanthin Induces Apoptosis in MCF-7 Cells through a p53-Dependent Pathway
- in-vitro, BC, MCF7
antiOx↑, AntiTum↑, TumCD↑, P53↑, P21↑, Apoptosis↑, Dose↝, Casp3↑,
4818- ASTX,  MEL,    Effect of astaxanthin and melatonin on cell viability and DNA damage in human breast cancer cell lines
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, T47D - in-vitro, Nor, MCF10
TumCD↑, DNAdam↑, *antiOx↑, *AntiTum↑, Inflam↓, tumCV↓, Bcl-2↓, Apoptosis↓, selectivity↑, eff↑, Dose↓,
4817- ASTX,    Low Dose Astaxanthin Treatments Trigger the Hormesis of Human Astroglioma Cells by Up-Regulating the Cyclin-Dependent Kinase and Down-Regulated the Tumor Suppressor Protein P53
- in-vitro, GBM, U251
Dose⇅, ROS∅, SOD↑, CDK1↑, P53↓, TumCP⇅, ROS↑,
4815- ASTX,    The Promising Effects of Astaxanthin on Lung Diseases
- Review, Var, NA
Dose↑, *BioAv↝, *BioAv↝, *antiOx↑, *NRF2↑, *ERK↓,
5427- ASTX,    Astaxanthin and Cancer Chemoprevention
- Review, Var, NA
chemoP↑, AntiCan↑, chemoPv↑, Risk↓, lipid-P↓, Pain↓, BioAv↑, Dose↝,
5417- ASTX,    Comparative Pharmacokinetic Study of Standard Astaxanthin and its Micellar Formulation in Healthy Male Volunteers
- Study, Nor, NA
*antiOx↑, *BioAv↓, *Dose↝, *BioAv↑,
5447- ATV,    The Mevalonate Pathway, a Metabolic Target in Cancer Therapy
- Review, Var, NA
Risk↓, Dose↑, ChemoSen↑, chemoP↑, HMG-CoA↓, EMT↓, CSCs↓, HH↝, YAP/TEAD↝,
5445- ATV,    Atorvastatin
- NA, Nor, NA
*cardioP↑, *LDL↓, HMG-CoA↓, Half-Life↝, BioAv↓, Dose↝,
5366- AV,    Aloe vera: A review of toxicity and adverse clinical effects
- Review, Var, NA
*Dose↝, *toxicity↝, tumCV↓, *AntiAg↑,
5367- AV,  Rad,    Aloe vera for prevention of radiation-induced dermatitis: a self-controlled clinical trial
- Trial, Var, NA
radioP↑, Dose↝, eff↑,
5370- AV,    The Effect of Aloe Vera Solution on Chemotherapy-Induced Stomatitis in Clients with Lymphoma and Leukemia: A Randomized Controlled Clinical Trial
- Trial, AML, NA
Dose↝, stomatitis↓, Pain↓,
5572- B-Gluc,    The Effects of Orally Administered Beta-Glucan on Innate Immune Responses in Humans, a Randomized Open-Label Intervention Pilot-Study
- Study, Nor, NA
Imm↑, *Dose↝, *BioAv↓, *toxicity↑,
5570- B-Gluc,    Immunomodulation of Fungal β-Glucan in Host Defense Signaling by Dectin-1
- Review, Var, NA
Imm↑, BioAv↝, eff↑, AntiCan↑, Dectin1↝, Dose↝, BioAv↓,
5567- B-Gluc,    Trained immunity: A new player in cancer immunotherapy
- Review, Var, NA
Imm↑, ROS↑, Apoptosis↑, OS↑, TumMeta↓, Dose↝,
5498- Ba,    Inhibition of 12-lipoxygenase during baicalein-induced human lung nonsmall carcinoma H460 cell apoptosis
- in-vitro, Lung, H460
12LOX↓, Dose↝, TumCCA↑, CDK1↓, CycB/CCNB1↓, Apoptosis↑, Bcl-2↓, P53↑, BAX↑, TumCP↓,
5500- Ba,    Safety, tolerability, and pharmacokinetics of oral baicalein tablets in healthy Chinese subjects: A single‐center, randomized, double‐blind, placebo‐controlled multiple‐ascending‐dose study
- Trial, Nor, NA
*toxicity↓, *BioAv↑, *Half-Life↝, *Dose↝,
4304- Ba,    Baicalein inhibits heparin-induced Tau aggregation by initializing non-toxic Tau oligomer formation
- in-vitro, AD, NA
*tau↓, *Dose↝, *BioAv↓,
1520- Ba,    Baicalein Induces G2/M Cell Cycle Arrest Associated with ROS Generation and CHK2 Activation in Highly Invasive Human Ovarian Cancer Cells
- in-vitro, Ovarian, SKOV3 - in-vitro, Ovarian, TOV-21G
TumCG↓, TumCCA↑, ROS↑, DNAdam↑, Chk2↑, Dose∅, p‑γH2AX↑, CDC25↓, CHK1↓, cycD1/CCND1↓, eff↓, 12LOX↓,
1519- Ba,    Baicalein inhibits KB oral cancer cells by inducing apoptosis via modulation of ROS
- in-vitro, Oral, KB
Apoptosis↑, Dose∅, ROS↑,
2481- Ba,  Rad,    Radiotherapy Increases 12-LOX and CCL5 Levels in Esophageal Cancer Cells and Promotes Cancer Metastasis via THP-1-Derived Macrophages
- in-vitro, ESCC, Eca109 - in-vitro, ESCC, KYSE150
12LOX↓, RadioS↑, Dose↝, RANTES↓, MCP1/CCL2↓,
2605- Ba,  BA,    Potential therapeutic effects of baicalin and baicalein
- Review, Var, NA - Review, Stroke, NA - Review, IBD, NA - Review, Arthritis, NA - Review, AD, NA - Review, Park, NA
cardioP↑, Inflam↓, cognitive↑, *hepatoP↑, *ROS?, *SOD↑, *GSH↑, *MMP↑, *GutMicro↑, ChemoSen↑, *TNF-α↓, *IL10↑, *IL6↓, *eff↑, *ROS↓, *COX2/PTGS2↓, *NF-kB↓, *STAT3↓, *PGE2↓, *MPO↓, *IL1β↓, *MMP2↓, *MMP9↓, *β-Amyloid↓, *neuroP↑, *Dose↝, *BioAv↝, *BioAv↝, *BBB↑, *BDNF↑,
2597- Ba,    Baicalein – An Intriguing Therapeutic Phytochemical in Pancreatic Cancer
- Review, PC, NA
chemoP↑, ChemoSen↑, 12LOX?, Bcl-2↓, BAX↑, Mcl-1↓, ERK↓, Prx6↑, Dose↝, BioAv↓, eff↑,
2612- Ba,  MF,    The effect of a static magnetic field and baicalin or baicalein interactions on amelanotic melanoma cell cultures (C32)
- in-vitro, Melanoma, NA
SOD1↑, SOD2↑, GPx1↑, Dose?, eff↝, SOD1↓, SOD2↓, GPx1↓,
2689- BBR,    Berberine protects against glutamate-induced oxidative stress and apoptosis in PC12 and N2a cells
- in-vitro, Nor, PC12 - in-vitro, AD, NA - in-vitro, Stroke, NA
*ROS↓, *lipid-P↓, *DNAdam↓, *GSH↑, *SOD↑, *eff↑, *cl‑Casp3↓, *BAX↓, *neuroP↑, *Dose↝, *Ca+2↓,
2692- BBR,    Berberine affects osteosarcoma via downregulating the caspase-1/IL-1β signaling axis
- in-vitro, OS, MG63 - in-vitro, OS, SaOS2 - in-vivo, NA, NA
Casp1↓, IL1β↓, TumCG↓, Dose↝, Apoptosis↑, Inflam↓,
2686- BBR,    Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs
- Review, Nor, NA
Inflam↓, IL6↓, MCP1/CCL2↓, COX2/PTGS2↓, PGE2↓, MMP2↓, MMP9↓, DNAdam↑, eff↝, Telomerase↓, Bcl-2↓, AMPK↑, ROS↑, MMP↓, ATP↓, p‑mTORC1↓, p‑S6K↓, ERK↓, PI3K↓, PTEN↑, Akt↓, Raf↓, MEK↓, Dose↓, Dose↑, selectivity↑, TumCCA↑, eff↑, EGFR↓, Glycolysis↓, Dose?, p27/CDKN1B↑, CDK2↓, CDK4↓, cycD1/CCND1↓, cycE/CCNE↓, Bax:Bcl2↑, Casp3↑, Casp9↑, VEGFR2/KDR/Flk1↓, ChemoSen↑, eff↑, eff↑, PGE2↓, JAK2↓, STAT3↓, CXCR4↓, CCR7↓, uPA↓, CSCs↓, EMT↓, Diff↓, CD133↓, Nestin↓, n-MYC↓, NOTCH↓, SOX2↓, Hif1a↓, VEGF↓, RadioS↑,
3677- BBR,    Berberine: A Potential Multipotent Natural Product to Combat Alzheimer’s Disease
- Review, AD, NA
*antiOx↑, *AChE↓, *BChE↓, *MAOA↓, *Aβ↓, *LDL↓, *ROS↓, *RNS↓, *lipid-P↓, *Dose↝, *MAOB↓, *memory↑, *toxicity↓, *BBB↑,
5631- BCA,    Perspectives Regarding the Role of Biochanin A in Humans
- Review, Var, NA - Review, AD, NA
*BioAv↓, *Inflam↓, AntiCan↑, *neuroP↑, chemoPv↑, Dose↝, *SOD↑, *MDA↓, *BAX↓, *HSP70/HSPA5↑, *AntiDiabetic↑, *Insulin↑, *TNF-α↓, *IL1β↓, *IL6↓, *iNOS↓, *COX2/PTGS2↓, *MMP9↓, *ROS↓, *PGE2↓, *BACE/β-secretase↓, *BioAv↑, P-gp/ABCB1⇅,
6518- BCP,    beta-Caryophyllene Induces Apoptosis and Inhibits Angiogenesis in Colorectal Cancer Models
- vitro+vivo, CRC, HCT116
angioG↓, VEGF↓, TumVol↓, HSP60/HSPD1↓, HTRA↓, survivin↓, XIAP↓, P21↑, TumCP↓, TumCMig↓, TumCG↓, Dose↝,
6503- BCP,    The Potential Therapeutic Role of Beta-Caryophyllene as a Chemosensitizer and an Inhibitor of Angiogenesis in Cancer
- Review, Var, NA
ChemoSen↑, angioG↓, TumCI↓, TumMeta↓, ROS↑, *ROS↓, chemoP↑, CB2 / CNR2↑, Inflam↓, AntiTum↑, *BioAv↑, *BBB↑, Apoptosis↑, TumCP↑, TumCCA↑, RadioS↑, DNArepair↓, ROS↑, STAT3↓, *BioEnh↑, Pain↓, AntiBio↓, ROS↑, Dose↝, NF-kB↓, MAPK↓, TNF-α↓, IL1β↓, IL6↓, cl‑PARP↑, Casp↑, BAX↑, Bcl-2↓, VEGF↓, VEGFR2/KDR/Flk1↓, MMP2↓, p‑p38↓, p‑ERK↓, EPR↑, P-gp/ABCB1↓, MRP1/ABCC1↓, *NRF2↑, *antiOx↑,
5514- bemA,    Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients
- Trial, Nor, NA
*ACLY↓, *LDL↓, *MusCon↓, Dose↝, cardioP↑,
2721- BetA,    Proteomic Investigation into Betulinic Acid-Induced Apoptosis of Human Cervical Cancer HeLa Cells
- in-vitro, Cerv, HeLa
ROS↑, Dose↝, Bcl-2↓, BAX↑, ER Stress↑,
2734- BetA,    Betulinic Acid Modulates the Expression of HSPA and Activates Apoptosis in Two Cell Lines of Human Colorectal Cancer
- in-vitro, CRC, HCT116 - in-vitro, CRC, SW480
tumCV↓, HSP70/HSPA5⇅, ROS↑, cl‑Casp3↑, mt-Apoptosis↑, Dose↝,
1566- betaCar,  Lyco,    Antioxidant and pro-oxidant effects of lycopene in comparison with beta-carotene on oxidant-induced damage in Hs68 cells
- in-vitro, Nor, HS68
*ROS↑, *ROS⇅, *Dose?,
5557- betaCar,    The Effect of Beta-Carotene on Cognitive Function: A Systematic Review
- Review, Nor, NA
*antiOx↑, *cognitive↑, *Dose↝, *eff↑,
5518- BEV,  Chemo,    Bevacizumab
- Review, Var, NA - Review, AMD, NA
Dose↝, other↑, VEGF↓, eff↑, Half-Life↑,
5716- BF,    Pilot Study of Huachansu in Patients with Hepatocellular Carcinoma, Non-Small Cell Lung Cancer, or Pancreatic Cancer
- Trial, NSCLC, NA - Trial, PC, NA - Trial, HCC, NA
Dose↝, toxicity↓, other↓, QoL↑, OS?,
5597- Bical,    Bicalutamide: clinical pharmacokinetics and metabolism
- Review, Pca, NA
Dose↝, BioAv↑, Half-Life↑, CYP3A4↓, PSA↓,
2502- Bical,    Complete Response of Metastatic Androgen Receptor–Positive Breast Cancer to Bicalutamide: Case Report and Review of the Literature
- Case Report, BC, NA
Dose↝, Remission↑,
5692- BJ,    Seed oil of Brucea javanica induces apoptosis through the PI3K/Akt signaling pathway in acute lymphocytic leukemia Jurkat cells
- vitro+vivo, AML, NA
Apoptosis↑, Akt↓, P53↑, FOXO1↑, GSK‐3β↑, TumVol↓, QoL↑, BBB↑, OS↑, Dose↝, MMP↓, ROS↑, XIAP↑, Casp9↑, Casp8↑, Casp3↑, cl‑PARP↑, TumCCA↑,
5473- BM,    Bacopa monnieri: Preclinical and Clinical Evidence of Neuroactive Effects, Safety of Use and the Search for Improved Bioavailability
- in-vivo, AD, NA - in-vivo, Park, NA
*neuroP↑, *toxicity∅, *AChE↓, *ROS↓, *antiOx↑, *lipid-P↓, *cognitive↑, *memory↑, *Dose↝, *BioAv↓, *TumCCA↑, *BBB↝,
5680- BML,    Anticancer properties of bromelain: State-of-the-art and recent trends
- Review, Var, NA
*Inflam↓, *Bacteria↓, *Pain↓, *Diar↓, *Wound Healing↑, ERK↓, JNK↓, XIAP↓, HSP27↓, β-catenin/ZEB1↓, HO-1↓, lipid-P↓, ACSL4↑, ROS↑, SOD↑, Catalase↓, GSH↓, MDA↓, Casp3↓, Casp9↑, DNAdam↑, Apoptosis↑, NF-kB↓, P53↑, MAPK↓, APAF1↑, Cyt‑c↓, CD44↓, Imm↑, ATG5↑, LC3I↑, Beclin-1/ATG6↑, IL2↓, IL4↓, IFN-γ↓, COX2/PTGS2↓, iNOS↓, ChemoSen↑, RadioS↑, Dose↝, other↓,
5676- BML,    Intestinal absorption of undegraded proteins in men: presence of bromelain in plasma after oral intake
- in-vivo, NA, NA
Half-Life↝, Dose↝, Dose↝,
5682- BML,    A novel treatment of bromelain and acetylcysteine (BromAc) in patients with peritoneal mucinous tumours: A phase I first in man study
- Human, Var, NA
Dose↝, toxicity↝, eff↑,
5649- BNL,    Borneol, a novel agent that improves central nervous system drug delivery by enhancing blood–brain barrier permeability
- Review, Nor, NA
*BBB↑, *other↑, *P-gp/ABCB1↓, *toxicity⇅, *BioAv⇅, *Dose↑, *ABC↓, *MRP1/ABCC1↓, *5HT↑, *GABA↑, *eff↑,
5650- BNL,    Borneol Depresses P-Glycoprotein Function by a NF-κB Signaling Mediated Mechanism in a Blood Brain Barrier in Vitro Model
- in-vivo, Nor, NA
*P-gp/ABCB1↓, *NF-kB↑, *eff↓, *Dose↝,
5666- BNL,    Exploring the potential to enhance drug distribution in the brain subregion via intranasal delivery of nanoemulsion in combination with borneol as a guider
- in-vivo, AD, NA
*BioAv↑, *eff↑, *Dose↝, *P-gp/ABCB1↓, *BBB↑, *NF-kB↓, *IL1β↓, *MMP9↓,

Showing Research Papers: 101 to 150 of 1061
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1061

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↓, 1,   HSP60/HSPD1↓, 1,   HTRA↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   Catalase↓, 1,   GPx1↓, 1,   GPx1↑, 1,   GSH↓, 1,   HO-1↓, 1,   HO-1↑, 1,   lipid-P↓, 2,   MDA↓, 1,   NQO1↑, 1,   NRF2↑, 1,   OXPHOS↓, 1,   Prx6↑, 1,   ROS↓, 1,   ROS↑, 13,   ROS∅, 1,   SOD↑, 2,   SOD1↓, 1,   SOD1↑, 1,   SOD2↓, 1,   SOD2↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 1,   CDC25↓, 1,   MEK↓, 1,   MMP↓, 2,   Raf↓, 1,   XIAP↓, 3,   XIAP↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX?, 1,   12LOX↓, 3,   ACLY↓, 1,   ACSL4↑, 1,   AMPK↑, 2,   CYP3A4↓, 1,   FASN↓, 1,   Glycolysis↓, 1,   HMG-CoA↓, 2,   LDH↓, 1,   p‑S6K↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 3,   APAF1↑, 1,   Apoptosis↓, 1,   Apoptosis↑, 10,   mt-Apoptosis↑, 1,   BAX↑, 4,   Bax:Bcl2↑, 2,   Bcl-2↓, 7,   Casp↑, 1,   Casp1↓, 1,   Casp3↓, 1,   Casp3↑, 4,   cl‑Casp3↑, 1,   Casp8↑, 1,   Casp9↑, 3,   Chk2↑, 1,   Cyt‑c↓, 1,   DR5↑, 1,   iNOS↓, 1,   JNK↓, 1,   JNK↑, 1,   MAPK↓, 2,   Mcl-1↓, 1,   p27/CDKN1B↑, 1,   p‑p38↓, 1,   p‑RSK↑, 1,   survivin↓, 2,   Telomerase↓, 1,   TumCD↑, 2,   YAP/TEAD↝, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↓, 2,   other↑, 2,   tumCV↓, 3,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,   ER Stress↑, 1,   HSP27↓, 1,   HSP70/HSPA5⇅, 1,   HSP90↓, 1,   PERK↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   Beclin-1/ATG6↑, 1,   LC3I↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

CHK1↓, 1,   DNAdam↑, 4,   DNArepair↓, 1,   DNMTs↓, 1,   P53↓, 1,   P53↑, 4,   cl‑PARP↑, 2,   PCNA↓, 1,   p‑γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK1↑, 1,   CDK2↓, 1,   CDK4↓, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 2,   cycE/CCNE↓, 1,   P21↑, 2,   TumCCA↑, 6,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD133↓, 1,   CD44↓, 1,   CSCs↓, 3,   Diff↓, 1,   EMT↓, 3,   ERK↓, 3,   p‑ERK↓, 1,   FOXO1↑, 1,   FOXO3↑, 1,   GSK‐3β↑, 1,   HH↝, 1,   mTOR↓, 1,   p‑mTORC1↓, 1,   n-MYC↓, 1,   Nestin↓, 1,   NOTCH↓, 1,   NOTCH3↓, 1,   PI3K↓, 2,   PTEN↑, 1,   SOX2↓, 1,   STAT3↓, 3,   TumCG↓, 4,  

Migration(tgid=13) ⓘ

Ki-67↓, 1,   MMP2↓, 2,   MMP9↓, 1,   N-cadherin↓, 1,   TumCI↓, 1,   TumCMig↓, 1,   TumCP↓, 3,   TumCP↑, 1,   TumCP⇅, 1,   TumMeta↓, 2,   uPA↓, 1,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 2,   EGFR↓, 1,   EPR↑, 2,   Hif1a↓, 1,   VEGF↓, 4,   VEGFR2/KDR/Flk1↓, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   P-gp/ABCB1↓, 1,   P-gp/ABCB1⇅, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CB2 / CNR2↑, 1,   CCR7↓, 1,   COX2/PTGS2↓, 2,   CXCR4↓, 1,   Dectin1↝, 1,   IFN-γ↓, 1,   IL1β↓, 2,   IL2↓, 1,   IL4↓, 1,   IL6↓, 3,   Imm↑, 4,   Inflam↓, 5,   JAK2↓, 1,   MCP1/CCL2↓, 2,   NF-kB↓, 3,   PGE2↓, 2,   PSA↓, 1,   RANTES↓, 1,   TNF-α↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 4,   BioAv↑, 3,   BioAv↝, 1,   ChemoSen↑, 6,   Dose?, 3,   Dose↓, 2,   Dose↑, 3,   Dose⇅, 1,   Dose↝, 28,   Dose∅, 2,   eff↓, 1,   eff↑, 11,   eff↝, 3,   Half-Life↑, 2,   Half-Life↝, 2,   MRP1/ABCC1↓, 1,   RadioS↑, 5,   selectivity↑, 2,  

Clinical Biomarkers(tgid=22) ⓘ

BG↓, 1,   EGFR↓, 1,   IL6↓, 3,   Ki-67↓, 1,   LDH↓, 1,   PSA↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 3,   AntiTum↑, 2,   cardioP↑, 2,   chemoP↑, 4,   chemoPv↑, 2,   cognitive↑, 1,   neuroP↑, 1,   OS?, 1,   OS↑, 2,   Pain↓, 3,   QoL↑, 2,   radioP↑, 1,   Remission↑, 1,   Risk↓, 2,   stomatitis↓, 1,   toxicity↓, 2,   toxicity↝, 2,   TumVol↓, 2,   TumW↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

Dectin1↝, 1,  
Total Targets: 208

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 7,   GSH↑, 2,   lipid-P↓, 3,   MDA↓, 1,   MPO↓, 1,   NRF2↑, 2,   RNS↓, 1,   ROS?, 1,   ROS↓, 6,   ROS↑, 1,   ROS⇅, 1,   SOD↑, 3,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

Insulin↑, 1,   MMP↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACLY↓, 1,   AMPK↑, 1,   LDL↓, 3,   p‑PPARγ↓, 1,  

Cell Death(tgid=5) ⓘ

BAX↓, 2,   cl‑Casp3↓, 1,   iNOS↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

HSP70/HSPA5↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↓, 1,   STAT3↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   Ca+2↓, 1,   MMP2↓, 1,   MMP9↓, 3,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 5,   BBB↝, 1,   P-gp/ABCB1↓, 3,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 2,   IL10↑, 1,   IL18↓, 1,   IL1β↓, 4,   IL6↓, 3,   IL8↓, 1,   Inflam↓, 2,   NF-kB↓, 2,   NF-kB↑, 1,   PGE2↓, 2,   TNF-α↓, 3,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   AChE↓, 2,   BChE↓, 1,   BDNF↑, 1,   GABA↑, 1,   MAOA↓, 1,   tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,   BACE/β-secretase↓, 1,   MAOB↓, 1,   β-Amyloid↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABC↓, 1,   BioAv↓, 5,   BioAv↑, 5,   BioAv⇅, 1,   BioAv↝, 5,   BioEnh↑, 1,   Dose?, 1,   Dose↑, 2,   Dose↝, 12,   eff↓, 1,   eff↑, 5,   Half-Life↝, 3,   MRP1/ABCC1↓, 1,  

Clinical Biomarkers(tgid=22) ⓘ

GutMicro↑, 1,   IL6↓, 3,  

Functional Outcomes(tgid=23) ⓘ

AntiDiabetic↑, 1,   AntiTum↑, 1,   cardioP↑, 2,   chemoPv↑, 1,   cognitive↑, 2,   hepatoP↑, 1,   memory↑, 2,   MusCon↓, 1,   neuroP↑, 4,   Pain↓, 1,   toxicity↓, 2,   toxicity↑, 1,   toxicity⇅, 1,   toxicity↝, 1,   toxicity∅, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,   Diar↓, 1,  
Total Targets: 89

Scientific Paper Hit Count for: Dose, Dosage
39 Magnetic Fields
31 Selenium NanoParticles
27 Hydrogen Gas
24 Radiotherapy/Radiation
22 Curcumin
19 Silver-NanoParticles
19 Resveratrol
19 Chemotherapy
17 Vitamin C (Ascorbic Acid)
16 EGCG (Epigallocatechin Gallate)
16 Selenium
16 Selenite (Sodium)
15 Ginkgo biloba-EGb 761
14 Apigenin (mainly Parsley)
14 Propolis -bee glue
14 Chlorogenic acid
12 Carvacrol
12 Ginger/6-Shogaol/Gingerol
12 Inositol
12 Kaempferol
11 buckwheat sprouts
11 Choline
11 Ellagic acid
11 Sulforaphane (mainly Broccoli)
11 Folic Acid, Vit B9
11 Hyperthermia
10 isoquercitrin
10 Lycopene
10 Hydroxycinnamic-acid
10 Lemongrass Extract/Citral
10 Lactoferrin/Talactoferrin
9 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
9 Baicalein
9 Dichloroacetate
9 Exercise
9 itraconazole
9 Magnetic Field Rotating
8 Rutin
8 Auranofin
8 Melatonin
8 Citric Acid
8 Dandelion Root
8 Ferulic acid
8 Fenbendazole
8 Fisetin
8 Fucoidan
8 Ginkgo biloba
8 Ginkgetin
8 HydroxyTyrosol
8 Silymarin (Milk Thistle) silibinin
7 3-bromopyruvate
7 α-Bisabolol / Chamomile oil
7 Quercetin
7 Mung Bean Sprouts
7 Capsaicin
7 Centella asiatica / Gotu kola → asiaticoside
7 chitosan
7 Echinacea
7 Electrical Pulses
7 Formononetin
7 Gamma-aminobutyric acid
7 Genistein (soy isoflavone)
7 Hibiscus sabdariffa
7 Indole-3-carbinol
7 Thymoquinone
7 Whole Body Vibration
6 5-Hydroxytryptophan
6 Metformin
6 Aspirin
6 Astaxanthin
6 Vitexin
6 Caffeic acid
6 immunotherapy
6 nicotinamide adenine dinucleotide
6 Copper and Cu NanoParticles
6 Eugenol
6 Ivermectin
6 Vitamin D3
6 Honokiol
6 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
6 iodine
6 Inulin Prebiotic
6 SonoDynamic Therapy UltraSound
6 Phenethyl isothiocyanate
5 Alpha-Lipoic-Acid
5 Cynara scolymus/Globe Artichoke/Artichoke Extract
5 Allicin (mainly Garlic)
5 Acetyl-l-carnitine
5 Paclitaxel/Taxol
5 Boron
5 isoorientin
5 Isovitexin
5 Chocolate
5 Spermidine
5 Oxygen, Hyperbaric
5 diet FMD Fasting Mimicking Diet
5 Vitamin B12
5 Gossypol/AT-101
5 Grapeseed extract
5 Isoliquiritigenin
5 Licorice
5 isoflavones
5 Licochalcone A
5 Bicarbonate(Sodium)
5 Phenylbutyrate
5 EMF
5 Rosmarinic acid
5 VitK3,menadione
4 cetuximab
4 Cisplatin
4 Ashwagandha(Withaferin A)
4 Berberine
4 Boswellia (frankincense)
4 Butyrate
4 Celastrol
4 Chrysin
4 Chyawanprash
4 Cichoric acid / Chicoric acid
4 Coenzyme Q10
4 HydroxyCitric Acid
4 Garcinol
4 Diclofenac
4 Docosahexaenoic Acid
4 eicosapentaenoic acid
4 Shilajit/Fulvic Acid
4 Gallic acid
4 capecitabine
4 probiotics
4 Propyl gallate
3 Astragalus
3 Fennel Oil/Foeniculum vulgare
3 Angelica archangelica / Garden Angelica
3 Artemisinin
3 Aloe anthraquinones
3 beta-glucans
3 Beta-Caryophyllene
3 Bromelain
3 borneol
3 Cat’s Claw
3 chaetocin
3 doxorubicin
3 Calorie Restriction Mimetics
3 Crocetin
3 Dasatinib/Phyrago
3 Disulfiram
3 Eurycomanone
3 Silicic Acid
3 Gambogic Acid
3 Huperzine A/Huperzia serrata
3 Isobavachalcone
3 Lapatinib
3 metronomic chemo
3 Methylsulfonylmethane
3 Oleuropein
3 Piperlongumine
3 Shikonin
3 Aflavin-3,3′-digallate
3 Turmerones
3 Urolithin
3 Vitamin B1/Thiamine
3 Vitamin E
3 Vitamin K2
2 1,8-Cineole
2 Photodynamic Therapy
2 Glucose
2 almonertinib
2 Bevacizumab (brand Avastin)
2 DTS(dibenzyl trisulphide) from Anamu
2 Anti-oxidants
2 Ascorbyl Palmitate
2 Atorvastatin
2 Betulinic acid
2 beta-carotene(VitA)
2 Bicalutamide
2 Bortezomib
2 Lecithin
2 Calcium
2 Sorafenib (brand name Nexavar)
2 Celecoxib
2 Cynaropicrin
2 diet Plant based
2 diet Short Term Fasting
2 D-limonene
2 Emodin
2 5-fluorouracil
2 Evodiamine
2 Vitamin B6,pyridoxine
2 Flickering Light Stimulation
2 Germanium Organic/Ge-132 / propagermanium (organogermanium)
2 Germanium inorganic
2 Geraniol
2 Ginkgolide B
2 Gold NanoParticles
2 Germacranolide sesquiterpene lactone
2 Helleborus niger extracts – Christmas Rose
2 Recombinant Methioninase
2 Juglone
2 Potassium
2 L-ornithine
2 Lactobacillus
2 Luteolin
2 nivolumab
2 Iron
2 Niclosamide (Niclocide)
2 Bifidobacterium
2 Phosphatidylserine
2 Rauwolfia serpentina/Indian Snakeroot
2 Vitamin B5,Pantothenic Acid
1 5-Aminolevulinic acid
1 Annona atemoya Leaf Extract
1 Anethole/trans-Anethole
1 Acer okamotoanum
1 Aromatherapy
1 Baicalin
1 Biochanin A
1 bempedoic acid
1 Bufalin/Huachansu
1 Brucea javanica
1 Bacopa monnieri
1 brusatol
1 Bruteridin(bergamot juice)
1 Black Seed Oil/Nigella sativa
1 urea
1 Catechins
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Cannabidiol
1 Chlorophyllin
1 Cinnamon
1 Carica papaya leaf extract
1 Camptothecin
1 CUSP9
1 Cysteamine
1 diet Ketogenic
1 Dipyridamole
1 Docetaxel
1 Zinc
1 Protocatechuic acid
1 Estragole
1 Aluminum
1 ferumoxytol
1 Auditory Gamma Stimulation / 40 Hz Auditory Stimulation
1 Arsenic trioxide
1 Vitamin A, Retinoic Acid
1 Bifidobacterium animalis subsp. lactis GCL2505
1 Glabrescione B
1 carboplatin
1 Graviola
1 hydrogen sulfide
1 High-Ozonide Oil
1 Hormone replacement therapy
1 Hyperoside
1 Extracorporeal Shock Wave Therapy
1 Anthocyanins
1 Gemcitabine (Gemzar)
1 lambertianic acid
1 Lapachol
1 Lasiodin
1 MCToil
1 Sulodexide
1 magnetic nanoparticles
1 Mistletoe/Viscum album Extracts
1 Mushroom Lion’s Mane
1 Naringin
1 Nimbolide
1 ipilimumab
1 Aidi injection
1 Phenolic Acids
1 Polyphenols
1 alpha Linolenic acid
1 Pterostilbene
1 Ramucirumab (CYRAMZA)
1 Radio Frequency
1 Sinapic acid
1 salinomycin
1 α-Santalol/Sandalwood oil
1 Sulfasalazine
1 irinotecan
1 Terpinen-4-ol / Tea Tree Oil
1 Taurine
1 Triphala
1 triptolide
1 Thymol-Thymus vulgaris
1 Ursolic acid
1 Vanillic Acid
1 Transarterial Chemoembolization
1 Xylitol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1114  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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