Imm Cancer Research Results

Imm, immunostimulatory: Click to Expand ⟱
Source:
Type:
Enhance the immune response in patients.
Scientific Papers found: Click to Expand⟱
6609- Ech,  Cic,    Echinacea purpurea Extract Enhances Natural Killer Cell Activity In Vivo by Upregulating MHC II and Th1-type CD4+ T Cell Responses
- in-vivo, Nor, NA
*Dose↝, *CD4+↑, *Th1 response↑, *NK cell↑, *Imm↑,
6610- Ech,  Cic,    A standardized extract of Echinacea purpurea containing higher chicoric acid content enhances immune function in murine macrophages and cyclophosphamide-induced immunosuppression mice
- in-vivo, Nor, NA
*NK cell↑, *Imm↑, Dose↝,
6634- Ech,    Echinacea purpurea: Pharmacology, phytochemistry and analysis methods
- Review, Var, NA
AntiArt↑, *Imm↑, *Neut↑, *NK cell↑, *COX1↓, *COX2/PTGS2↓, *Inflam↓, TumCG↑, *toxicity↓,
6620- Ech,    Echinacea purpurea diminishes neovascular reaction induced in mice skin by human cancer cells and stimulates non-specific cellular immunity in humans
- in-vivo, Var, NA
angioG↓, *NK cell↑, Imm↑, Inflam↓, tumCV↓, Apoptosis↑, Casp3↑, Casp7↑, DNAdam↑, MMPs↓, other↑,
6619- Ech,    Echinacea Reduces Antibiotics by Preventing Respiratory Infections: A Meta-Analysis (ERA-PRIMA)
- Review, Nor, NA
*eff↑, *Imm↑, *AntiViral↑,
6777- EGCG,    Health Benefits and Chemical Composition of Matcha Green Tea: A Review
- Review, Nor, NA
*antiOx↑, *Inflam↓, AntiCan↑, Risk↓, TumCG↓, Apoptosis↑, *ROS↓, *cardioP↑, *Imm↑, *AntiViral↑, *cognitive↑,
6784- EGCG,    Dietary (−)-Epigallocatechin Gallate (EGCG): State-of-the-Art Advances in Bioactivities, Bioavailability Enhancement Strategies, and Applications in Nutrition and Health
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiCan↑, *cardioP↑, *neuroP↑, *GutMicro↑, *AntiBio↑, *ROS↓, *TNF-α↓, *IL6↓, TumCP↓, *LDL↓, *NO↓, *Obesity↓, *p‑tau↓, *Aβ↓, *NRF2↑, *SOD↑, *Catalase↑, *GPx↑, *NLRP3↓, *mTOR↓, TumCCA↑, NRF2↓, Apoptosis↑, SIRT1↓, miR-25-5p↓, PARP↑, Casp3↑, Casp9↑, ER Stress↑, TumAuto↑, EMT↓, TumCI↓, TumCMig↓, TGF-β↓, Smad1↓, STAT3↓, VEGF↓, angioG↓, Imm↑, EGFR↓, *GutMicro↑, *Bacteria↓, *AntiViral↑, *BioAv↓, *BioAv↑, *eff↑, *BioAv↑, eff↑, ChemoSen↑, *toxicity↝,
6825- EMD,    Advances in the pharmacological effects and molecular mechanisms of emodin in the treatment of metabolic diseases
- Review, Nor, NA
*Inflam↓, *AntiTum↑, *Bacteria↓, *Imm↑, *glucose↓, *RenoP↑, *TLR4↓, *MyD88↓, *NLRP3↓, *NF-kB↓, *PI3K↓, *mTOR↓, *GSK‐3β↓, *Hif1a↓, *VEGF↓, *GutMicro↑, *Obesity↓, *AntiDiabetic↑, *AMPK↑, *PPARγ↑, *PPARγ↓, *toxicity↝, *hepatoP↑, *AST↓, *ALAT↓,
6819- EMD,    Recent advances in the therapeutic potential of emodin for human health
- Review, Nor, NA
AntiCan↑, *AntiDiabetic↑, *neuroP↑, *Inflam↓, *antiOx↑, *BioAv↓, *BioAv↑, *SOD↑, *GPx↑, *GSH↑, *NRF2↑, *ROS↓, *lipid-P↓, *Cyt‑c↓, *BAX↓, *Bcl-2↓, *iNOS↓, *NO↓, *IL6↓, *IL10↓, *IL17↓, *IFN-γ↓, *NF-kB↓, *LC3II↓, *Akt↓, *Beclin-1/ATG6↓, *AMPK↓, *TNF-α↓, *PGE2↓, *Apoptosis↓, *Casp3↓, *Casp9↓, *P53↓, *P21↓, *NAD↓, *ATP↓, *CHOP/DDIT3↓, *GADD34↓, *ATF4↓, tumCV↓, Apoptosis↑, TumCG↓, TumCI↓, TumMeta↓, CSCs↓, NOTCH1↓, STAT3↓, eff↑, miR-34a↓, *neuroP↑, *BDNF↓, *hepatoP↑, *ALAT↓, *AST↓, TG/TAG↓, ROS↑, Slug↓, EMT↓, Glycolysis↓, ChemoSen↑, P-gp/ABCB1↓, Ki-67↓, PCNA↓, ER Stress↑, TRIB3↑, NF-kB↑, TumMeta↑, *Imm↓, *toxicity↝,
5256- EP,    Pulsed electric fields: a sharp sword in the battle against cancers
- Review, Var, NA
BioAv↑, TumCD↑, MMP↓, Apoptosis↑, TumCCA↑, Imm↑, RadioS↑, ChemoSen↑,
5487- EP,    High-frequency irreversible electroporation improves survival and immune cell infiltration in rodents with malignant gliomas
- in-vivo, GBM, NA
OS↑, CellMemb↑, Imm↑, Inflam↓, necrosis↑, Pyro↑, eff↑, IL2↑, IL6↑, IL17↑, IFN-γ↓,
5490- EP,    Application of Pulsed Electric Fields to Cancer Therapy
- Review, Var, NA
CellMemb↑, Ca+2↑, Imm↑, TumMeta↓,
5492- EP,    Nano-Pulse Stimulation Therapy in Oncology
- in-vivo, PC, Panc02 - in-vivo, BC, 4T1
CellMemb↑, Ca+2↑, DNAdam↑, eff↝, Imm↑,
5493- EP,    Schottky nanodiodes array enabled triboelectric nanosecond pulse generator for ultralow-cost tumor therapy
- Review, Var, NA
other↝, other↝, Ca+2↑, TumCD↑, Imm↑, TumCG↓, other↓,
5519- EP,    Nanosecond Pulsed Electric Fields (nsPEFs) for Precision Intracellular Oncotherapy: Recent Advances and Emerging Directions
- Review, Var, NA
MMP↓, Ca+2↑, eff↑, ER Stress↑, selectivity↑, CSCs↓, CD44↓, CD133↓, ROS↑, Imm↑, DNAdam↑, MOMP↑, Cyt‑c↑, Casp9↑, Casp3↑, Casp9↑, TumCD↑, Fas↑, UPR↑, Dose↝, Dose↝, Dose↓, Dose↑, HMGB1↓, eff↑, EPR↑, ChemoSen↑, ETC↝, *AntiAge↑, *Hif1a↑, *SIRT1↑,
6923- Flav,    Flavonoids: an overview
- Review, Nor, NA
*antiOx↑, AntiCan↑, *cardioP↑, *XO↓, *COX2/PTGS2↓, *5LO↓, *PI3K↓, *AChE↓, *Imm⇅, *BP↓, TumCCA↑, *Aβ↓, *BACE/β-secretase↓, *NF-kB↓, *ROS↓, *neuroP↑, *AntiAg↑, *AntiThr↑,
7013- Fuc,    Fucoidan-based nanoparticles for colorectal cancer therapy: Mechanisms and preclinical insights
- Review, CRC, NA
*Inflam↓, *antiOx↑, AntiCan↑, BioAv↑, Apoptosis↑, angioG↓, Imm↝, ChemoSen↑, chemoP↑,
7006- Fuc,    Seaweeds in the Oncology Arena: Anti-Cancer Potential of Fucoidan as a Drug—A Review
- Review, Var, NA
*toxicity↓, *AntiViral↑, *antiOx↑, *Imm⇅, AntiCan↑, TumCCA↑, Apoptosis↑, TumMeta↓, angioG↓, antiNeop↑, VEGF↓, MMPs↓, BioAv↑, BioAv↑, ROS⇅, cl‑PARP↑, Casp3↑, Casp7↑, ROS↑, GSH↓, MMP↓, PI3K↓, ERK↓, MAPK↑, TumCP↓, Bax:Bcl2↑, TJ↑, ZO-1↑, OCLN↑, CLDN1↑, IBI↑, GutMicro↑, NK cell↑, STAT3↓, eff↑,
7008- Fuc,    Ten Years of Research on Fucoidan and Cancer: Focus on Its Antiangiogenic and Antimetastatic Effects
- Review, Var, NA
antiOx↑, AntiViral↑, Imm↝, *AntiThr↑, *AntiDiabetic↑, AntiTum↑, TumMeta↑, angioG↓, Hif1a↓, VEGF↓, MMPs↓, EMT↓, N-cadherin↓, E-cadherin↑, TIMP1↑, PI3K↓, Akt↓, mTOR↓, MMP2↓, ChemoSen↑, OS↑, fatigue↓, CD31/PECAM-1↓,
7117- Ge-132,    Organogermanium suppresses cell death due to oxidative stress in normal human dermal fibroblasts
- in-vitro, Nor, NA
*IL6↓, *Apoptosis↓, *toxicity↓, Imm↑, IFN-γ↑, NK cell↑, AntiTum↑, Pain↓, *Wound Healing↑,
7126- Ge-132,    Immune activation of Bio-Germanium in a randomized, double-blind, placebo-controlled clinical trial with 130 human subjects: Therapeutic opportunities from new insights
- Trial, Nor, NA
AntiTum↑, AntiCan↑, *AntiAge↑, *AntiViral↑, *Inflam↓, *NK cell↑, *Imm↑, *TNF-α↑,
7125- Ge-132,    A review of public and environmental consequences of organic germanium
- Review, Nor, NA
*toxicity↓, other↝, Imm↑, anemia↓,
6771- GI,    A glimpse on influences of ginger and its derivatives as a feed additive in finfish farming: A mini-review
- Review, Nor, NA
*AntiBio↓, *Imm↑, *Inflam↓, *antiOx↑, *SOD↓, *Catalase↓, *GSH↓,
7250- Gink,    Ginkgetin from Ginkgo biloba: mechanistic insights into anticancer efficacy
- Review, Var, NA
AntiCan↑, toxicity↓, ChemoSen↑, chemoP↑, TumCCA↑, TumCD↑, TumCI↓, angioG↓, Ferroptosis↑, Imm↑, MOMP↑, Cyt‑c↑, Casp↑, cl‑Casp3↑, cl‑Casp9↑, cl‑PARP↑, Apoptosis↑, ROS↑, TumAuto↑, GPx4↓, xCT/SLC7A11↓, RadioS↑, NRF2↓, HO-1↓, HSP90↓, Dose↝, Dose↝, BioAv↓, BioAv↝, CYP3A4↓, *toxicity↑, *toxicity↝,
7321- Gos,    The potential roles of gossypol as anticancer agent: advances and future directions
- Review, Var, NA
other↝, BioAv↑, Bcl-2↓, Casp3↑, Casp9↑, MOMP↑, ROS↑, ATP↓, mtDam↑, Apoptosis↑, hTERT/TERT↓, Akt↓, TumAuto↑, LC3‑Ⅱ/LC3‑Ⅰ↑, NRF2↓, ARE↓, ICAM-1↓, CX43/GJA1↓, NF-kB↓, TLR4↓, IL6↓, Inflam↓, CUL5↝, CUL1↝, NOXA↑, TumCI↓, TumCMig↓, TumCA↓, FAK↓, MDM2↓, VEGF↓, angioG↓, HLA-I/II↑, Imm↑, Dose↝, Glycolysis↓, OXPHOS↓,
7482- H2,    Molecular Hydrogen Therapy: Mechanisms, Delivery Methods, Preventive, and Therapeutic Application
- Review, Var, NA - Review, IBD, NA - Review, Stroke, NA - Review, Sepsis, NA - Review, AD, NA
Dose↝, *Inflam↓, *IL1β↓, *IL6↓, *TNF-α↓, *neuroP↑, *mTOR↓, *IL10↑, *TGF-β↑, *Sepsis↓, *NRF2↑, *antiOx↑, *Catalase↑, *SOD↑, *GPx↑, *ROS↓, *HO-1↑, *PI3K↑, *Akt↑, *hepatoP↑, *MPO↓, *cardioP↑, CDK4↓, CDK6↑, CD47↓, PI3K↓, Akt↓, Hif1a↓, selectivity↑, *MMP↑, *ATP↑, *ER Stress↓, *CHOP/DDIT3↓, *Casp12↓, *GRP78/BiP↓, *p38↓, *p‑JNK↓, *LC3‑Ⅱ/LC3‑Ⅰ↑, *p‑eIF2α↓, *ATF4↓, *XBP-1↓, *Imm↑, *IFN-γ↓, *IL4↓, *GranB/GZMB↓, NK cell↑, radioP↑, *CD4+↑, CD8+↑, *Dose↝, *other↑, *Dose↝, *antiPs↑, *BioAv↝, *GutMicro↑, Dose↝, *IBI↑, TumCP↓, TumCI↓, TumCMig↓, CD8+↑, PGC-1α↑, Akt↓, SCD1↓, *MDA↓, eff↑, *APP↓, *BACE/β-secretase↓, *Aβ↓, *cognitive↑, *neuroP↑, NP/CIPN↓, *Stroke↓, *NLRP3↓, *ALAT↓, *AST↓, *LPS↓, *hepatoP↑, chemoP↑, *creat↓, *Urea↓, *RenoP↑, *eff↑, Apoptosis↑, XIAP↓, IAP2/BIRC3↓, TumVol↓, MALAT1↓, EZH2↓, miR-124-3p↓, eff↑, ChemoSen↑, *compII↑, *compIII↑, *LDL↓, *Obesity↓, QoL↑, PFS↑,
7505- HCQ,  GEM,  PacT,    A Randomized Phase II Preoperative Study of Autophagy Inhibition with High-Dose Hydroxychloroquine and Gemcitabine/Nab-Paclitaxel in Pancreatic Cancer Patients
- Trial, PC, NA
eff↑, TumAuto↓, Imm↑, CA19-9↓, OS↑,
7341- Hne,    Preclinical evaluation of safety and potential of black hellebore extracts for cancer treatment
- Review, Var, NA
angioG↓, TumCP↓, *Inflam↓, *Bacteria↓, *glucose↓, *neuroP↓, *hepatoP↓, *Imm↝,
7455- HNK,    Honokiol in cancer: Roles in enhancing combination therapy efficacy and preventing post-transplant malignancies
- Review, Var, NA
ChemoSen↑, Imm↝, *hepatoP↑, *cardioP↑, *neuroP↑, *AntiCan↑, *Inflam↓, *antiOx↑, eff↑, *TNF-α↓, *IL1?, *IL6?,
7599- HPT,  Rad,    Recent development on hyperthermia: An effective cotreatment improving radiotherapy outcome
- Review, Var, NA
NA↑, RadioS↑, DNArepair↓, Hypoxia↓, EPR↑, LC↑, OS↑, *toxicity↓, Dose↝, BloodF↑, pH↝, Imm↑, HSP70/HSPA5↑,
7619- HPT,    The role of hyperthermia in the treatment of tumor
Imm↑, RadioS↑, ChemoSen↑, EPR↑,
7620- HPT,    Hyperthermia and radiotherapy: physiological basis for a synergistic effect
- Review, Var, NA
RadioS↑, DNArepair↓, Hypoxia↓, CSCs↓, Imm↑, pH↝, HSPs↑, ROS↑, eff↑,
7575- HPT,  Rad,  Chemo,  immuno,    From Localized Mild Hyperthermia to Improved Tumor Oxygenation: Physiological Mechanisms Critically Involved in Oncologic Thermo-Radio-Immunotherapy
RadioS↑, ChemoSen↑, Imm↑, BloodF↑, Hypoxia↓, Dose↝, DNArepair↓, e-pH↓,
7572- HPT,  Rad,    The effect of thermal dose on hyperthermia-mediated inhibition of DNA repair through homologous recombination
- in-vitro, Cerv, HeLa - in-vitro, Laryn, FaDu
RadioS↑, TumCD↑, BRCA2↓, Dose↝, BloodF↑, ROS↑, Imm↑,
7600- I3C,    Indole-3-Carbinol (I3C) and its Major Derivatives: Their Pharmacokinetics and Important Roles in Hepatic Protection
- Review, Nor, NA
*ROS↓, *hepatoP↑, *AntiTum↑, *Imm↑, *Inflam↓,
7767- IBC,    Isobavachalcone exerts anti-gastric cancer effects by targeting dihydroorotate dehydrogenase to induce ROS release and activating the STING pathway
- vitro+vivo, GC, NA
TumCG↓, ROS↑, DHODH↓, MMP↓, cGAS–STING↑, Imm↑, mtDam↑,
7776- IBC,    Isobavachalcone Activates Antitumor Immunity on Orthotopic Pancreatic Cancer Model: A Screening and Validation
- vitro+vivo, PC, Panc02
TumCP↓, Apoptosis↑, ROS↑, TumW↓, CD8+↑, M2 MC↓, CSCs↓, antiNeop↑, Imm↑, eff↓, Bcl-2↓, BAX↑,
7635- Ins,    The Role of Inositols in Endocrine and Neuroendocrine Tumors
- Review, Thyroid, NA
*Dose↝, VEGF↓, Imm↑, NK cell↑, eff↑, PI3K↓, Akt↓, EMT↓, MAPK↓, Wnt↓, NF-kB↓, IRes↓, *ROS↓, TumVol↓, *TSHR↓,
7643- Ins,  IP6,    Efficacy of IP6 + inositol in the treatment of breast cancer patients receiving chemotherapy: prospective, randomized, pilot clinical stud
- Trial, BC, NA
RBC↑, QoL↑, eff↑, Imm↑, ChemoSen↑, chemoP↑, Dose↝,
7631- Ins,  IP6,    Broad Spectrum Anticancer Activity of Myo-Inositol and Inositol Hexakisphosphate
- Review, Var, NA
other↑, p‑pRB↓, TumCCA↑, PI3K↓, Akt↓, ERK↓, NF-kB↓, COX2/PTGS2↓, PGE2↓, PSEN1/PS1↓, EMT↓, Wnt↓, β-catenin/ZEB1↓, NOTCH1↓, N-cadherin↓, Snail↓, E-cadherin↑, fascin↓, Cofilin↓, MMPs↓, ROCK1↓, Dose↝, other↝, selectivity↑, *ROS↓, *lipid-P↓, ROS↑, NK cell↑, Imm↑, TNF-α↓, ChemoSen↑, Dose↑, toxicity↓, QoL↑, chemoP↑, OS↑, Dose↝, Insulin↓, glucose↝, lipoGen↓, eff↑,
7681- iod,  metroC,    Molecular Iodine Improves the Efficacy and Reduces the Side Effects of Metronomic Cyclophosphamide Treatment against Mammary Cancer Progression
- in-vivo, BC, NA
tumCV↓, Imm↑, chemoP↑, Weight↑, TumCG↓, VEGF↓, survivin↓, ChemoSen↑,
7652- IP,    Inulin prebiotic reinforces host cancer immunosurveillance via ɣδ T cell activation
- in-vivo, Melanoma, B16-F10
GutMicro↑, Imm↑, CD4+↑, CD8+↑, TumCG↓,
7667- IP,  H2,    Molecular hydrogen as a potential mediator of the antitumor effect of inulin consumption
*AntiTum↑, *other↑, *NA↝, *CD4+↑, *CD8+↑, TumCG↓, Imm↑,
7722- IP6,    Cancer inhibition by inositol hexaphosphate (IP6) and inositol: from laboratory to clinic
- Review, Var, NA
eff↑, TumCP↓, Diff↑, TumCCA↑, Imm↑, antiOx↑, BioAv↑, toxicity↓, ChemoSen↑, TumMeta↓, QoL↑,
7646- IP6,  Ins,    Protection against cancer by dietary IP6 and inositol
- Review, Var, NA
*antiOx↑, TumCG↓, TumMeta↓, Imm↑, kidSt↓, LDL↓, TumCCA↑, TumCP↓, Diff↑, ChemoSen↑, QoL↑,
7690- IP6,  Ins,    Inositol Hexaphosphate (IP6) and Colon Cancer: From Concepts and First Experiments to Clinical Application
- Review, Colon, NA
AntiCan↑, Imm↑, antiOx↑, TumCP↓, Diff↑, TumCG↓, eff↑, P21↓, p27/CDKN1B↓, pRB↓, TumCCA↑, PI3K↓, Akt↓, PKCδ↓, RAS↓, ERK↓, NF-kB↓, Inflam↓, MMP9↓, IronCh↑, NK cell↑, selectivity↑, ChemoSen↑, chemoP↑, toxicity↓, Remission↑,
7699- IP6,    IP6: From Seeds to Science—A Natural Compound’s Path to Clinical Promise
- Review, Var, NA
*Iron∅, ChemoSen↑, *cardioP↑, neuroP↑, IronCh∅, P21↓, p27/CDKN1B↓, p‑pRB↓, PI3K↓, Akt↓, NF-kB↓, Inflam↓, TumW↓, TumCI↓, TumMeta↓, Imm↑, Diff↑, selectivity↑, toxicity↓, RenoP↑, QoL↑,
8031- IVM,    Antiparasitic agents in oncology: Innovative mechanisms, emerging evidence and clinical potential in cancer treatment
*AntiP↑, Wnt↓, β-catenin/ZEB1↓, PI3K↓, Akt↓, mTOR↓, HH↓, Imm↑, CSCs↓, P-gp/ABCB1↓, Chl↓, angioG↓,
8026- IVM,  immuno,    Ivermectin converts cold tumors hot and synergizes with immune checkpoint blockade for treatment of breast cancer
- vitro+vivo, BC, 4T1
ICD↑, Imm↝, eff↑, TumVol↓,
7900- IVT,    Isovitexin: A Promising Active Compound Found in Nature's Bounty
- in-vivo, Nor, NA
*BioAv↓, *Imm↝, *antiOx↑, *AntiCan↑, *neuroP↑, *hepatoP↑, *Inflam↓, *NF-kB↓, *MAPK↓, *MPO↓, *ROS↓, TumAuto↑, Apoptosis↑,

Showing Research Papers: 101 to 150 of 191
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 191

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

anemia↓, 1,   AntiArt↑, 1,   CD47↓, 1,   CUL1↝, 1,   CUL5↝, 1,   CX43/GJA1↓, 1,   DHODH↓, 1,   HLA-I/II↑, 1,   IRes↓, 1,   kidSt↓, 1,   LC↑, 1,   miR-124-3p↓, 1,   NA↑, 1,   PFS↑, 1,   PSEN1/PS1↓, 1,   RBC↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 3,   ARE↓, 1,   Ferroptosis↑, 1,   GPx4↓, 1,   GSH↓, 1,   HO-1↓, 1,   ICD↑, 1,   NRF2↓, 3,   OXPHOS↓, 1,   ROS↑, 10,   ROS⇅, 1,   xCT/SLC7A11↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,   IronCh∅, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 1,   ETC↝, 1,   Insulin↓, 1,   MMP↓, 4,   mtDam↑, 2,   PGC-1α↑, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

CYP3A4↓, 1,   glucose↝, 1,   Glycolysis↓, 2,   LDL↓, 1,   lipoGen↓, 1,   SCD1↓, 1,   SIRT1↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 9,   Apoptosis↑, 12,   BAX↑, 1,   Bax:Bcl2↑, 1,   Bcl-2↓, 2,   Casp↑, 1,   Casp3↑, 5,   cl‑Casp3↑, 1,   Casp7↑, 2,   Casp9↑, 4,   cl‑Casp9↑, 1,   Cyt‑c↑, 2,   Fas↑, 1,   Ferroptosis↑, 1,   hTERT/TERT↓, 1,   IAP2/BIRC3↓, 1,   MAPK↓, 1,   MAPK↑, 1,   MDM2↓, 1,   MOMP↑, 3,   necrosis↑, 1,   NOXA↑, 1,   p27/CDKN1B↓, 2,   Pyro↑, 1,   survivin↓, 1,   TumCD↑, 5,  

Kinase & Signal Transduction(tgid=6) ⓘ

miR-25-5p↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

EZH2↓, 1,   other↓, 1,   other↑, 2,   other↝, 5,   pRB↓, 1,   p‑pRB↓, 2,   tumCV↓, 3,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↑, 3,   HSP70/HSPA5↑, 1,   HSP90↓, 1,   HSPs↑, 1,   UPR↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   TumAuto↓, 1,   TumAuto↑, 4,  

DNA Damage & Repair(tgid=10) ⓘ

BRCA2↓, 1,   DNAdam↑, 3,   DNArepair↓, 3,   PARP↑, 1,   cl‑PARP↑, 2,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK4↓, 1,   P21↓, 2,   TumCCA↑, 9,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD133↓, 1,   CD44↓, 1,   CSCs↓, 5,   Diff↑, 4,   EMT↓, 5,   ERK↓, 3,   HH↓, 1,   miR-34a↓, 1,   mTOR↓, 2,   NOTCH1↓, 2,   PI3K↓, 8,   RAS↓, 1,   STAT3↓, 3,   TumCG↓, 9,   TumCG↑, 1,   Wnt↓, 3,  

Migration(tgid=13) ⓘ

Ca+2↑, 4,   CD31/PECAM-1↓, 1,   Chl↓, 1,   CLDN1↑, 1,   Cofilin↓, 1,   E-cadherin↑, 2,   FAK↓, 1,   fascin↓, 1,   Ki-67↓, 1,   MALAT1↓, 1,   MMP2↓, 1,   MMP9↓, 1,   MMPs↓, 4,   N-cadherin↓, 2,   PKCδ↓, 1,   ROCK1↓, 1,   Slug↓, 1,   Smad1↓, 1,   Snail↓, 1,   TGF-β↓, 1,   TIMP1↑, 1,   TJ↑, 1,   TRIB3↑, 1,   TumCA↓, 1,   TumCI↓, 6,   TumCMig↓, 3,   TumCP↓, 8,   TumMeta↓, 6,   TumMeta↑, 2,   ZO-1↑, 1,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 9,   EGFR↓, 1,   EPR↑, 3,   Hif1a↓, 2,   Hypoxia↓, 3,   VEGF↓, 6,  

Barriers & Transport(tgid=15) ⓘ

CellMemb↑, 3,   IBI↑, 1,   OCLN↑, 1,   P-gp/ABCB1↓, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   COX2/PTGS2↓, 1,   HMGB1↓, 1,   ICAM-1↓, 1,   IFN-γ↓, 1,   IFN-γ↑, 1,   IL17↑, 1,   IL2↑, 1,   IL6↓, 1,   IL6↑, 1,   Imm↑, 31,   Imm↝, 4,   Inflam↓, 5,   M2 MC↓, 1,   NF-kB↓, 5,   NF-kB↑, 1,   NK cell↑, 6,   PGE2↓, 1,   TLR4↓, 1,   TNF-α↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

cGAS–STING↑, 1,   pH↝, 2,   e-pH↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CDK6↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 6,   BioAv↝, 1,   ChemoSen↑, 18,   Dose↓, 1,   Dose↑, 2,   Dose↝, 14,   eff↓, 1,   eff↑, 17,   eff↝, 1,   RadioS↑, 7,   selectivity↑, 5,  

Clinical Biomarkers(tgid=22) ⓘ

BloodF↑, 3,   CA19-9↓, 1,   EGFR↓, 1,   EZH2↓, 1,   GutMicro↑, 2,   hTERT/TERT↓, 1,   IL6↓, 1,   IL6↑, 1,   Ki-67↓, 1,   TG/TAG↓, 1,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 8,   antiNeop↑, 2,   AntiTum↑, 3,   chemoP↑, 7,   fatigue↓, 1,   neuroP↑, 1,   NP/CIPN↓, 1,   OS↑, 5,   Pain↓, 1,   QoL↑, 6,   radioP↑, 1,   Remission↑, 1,   RenoP↑, 1,   Risk↓, 1,   toxicity↓, 5,   TumVol↓, 3,   TumW↓, 2,   Weight↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 1,   CD8+↑, 4,  
Total Targets: 219

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↓, 1,   AntiBio↑, 1,   AntiP↑, 1,   compII↑, 1,   NA↝, 1,   Stroke↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 11,   Catalase↓, 1,   Catalase↑, 2,   GPx↑, 3,   GSH↓, 1,   GSH↑, 1,   HO-1↑, 1,   Iron∅, 1,   lipid-P↓, 2,   MDA↓, 1,   MPO↓, 2,   NRF2↑, 3,   ROS↓, 9,   SOD↓, 1,   SOD↑, 3,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 1,   ATP↑, 1,   compIII↑, 1,   MMP↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 3,   AMPK↓, 1,   AMPK↑, 1,   glucose↓, 2,   LDL↓, 2,   NAD↓, 1,   PPARγ↓, 1,   PPARγ↑, 1,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   Akt↑, 1,   Apoptosis↓, 2,   BAX↓, 1,   Bcl-2↓, 1,   Casp12↓, 1,   Casp3↓, 1,   Casp9↓, 1,   Cyt‑c↓, 1,   GADD34↓, 1,   GranB/GZMB↓, 1,   iNOS↓, 1,   p‑JNK↓, 1,   MAPK↓, 1,   p38↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 2,   other↑, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 2,   p‑eIF2α↓, 1,   ER Stress↓, 1,   GRP78/BiP↓, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3II↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

P53↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

P21↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

GSK‐3β↓, 1,   mTOR↓, 3,   PI3K↓, 2,   PI3K↑, 1,  

Migration(tgid=13) ⓘ

5LO↓, 1,   AntiAg↑, 1,   APP↓, 1,   TGF-β↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

ATF4↓, 2,   Hif1a↓, 1,   Hif1a↑, 1,   NO↓, 2,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

IBI↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 3,   COX1↓, 1,   COX2/PTGS2↓, 2,   IFN-γ↓, 2,   IL1?, 1,   IL10↓, 1,   IL10↑, 1,   IL17↓, 1,   IL1β↓, 1,   IL4↓, 1,   IL6?, 1,   IL6↓, 4,   Imm↓, 1,   Imm↑, 10,   Imm⇅, 2,   Imm↝, 2,   Inflam↓, 13,   LPS↓, 1,   MyD88↓, 1,   Neut↑, 1,   NF-kB↓, 4,   NK cell↑, 5,   PGE2↓, 1,   Th1 response↑, 1,   TLR4↓, 1,   TNF-α↓, 4,   TNF-α↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   BDNF↓, 1,   p‑tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 3,   BACE/β-secretase↓, 2,   NLRP3↓, 3,   XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

TSHR↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 3,   BioAv↑, 3,   BioAv↝, 1,   Dose↝, 4,   eff↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 3,   AST↓, 3,   BP↓, 1,   creat↓, 1,   GutMicro↑, 4,   IL6?, 1,   IL6↓, 4,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   AntiCan↑, 3,   AntiDiabetic↑, 3,   antiPs↑, 1,   AntiTum↑, 3,   cardioP↑, 6,   cognitive↑, 2,   hepatoP↓, 1,   hepatoP↑, 7,   neuroP↓, 1,   neuroP↑, 8,   Obesity↓, 3,   RenoP↑, 2,   toxicity↓, 5,   toxicity↑, 1,   toxicity↝, 4,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 5,   Bacteria↓, 3,   CD8+↑, 1,   Sepsis↓, 1,  
Total Targets: 144

Scientific Paper Hit Count for: Imm, immunostimulatory
14 Echinacea
13 beta-glucans
9 chitosan
8 immunotherapy
8 Lactoferrin/Talactoferrin
6 Dandelion Root
6 Electrical Pulses
6 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
6 Bicarbonate(Sodium)
5 Hyperthermia
5 Inositol
5 Selenite (Sodium)
4 Astragalus
4 Curcumin
4 Radiotherapy/Radiation
3 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
3 Bifidobacterium
3 Chemotherapy
3 Centella asiatica / Gotu kola → asiaticoside
3 Chyawanprash
3 Cichoric acid / Chicoric acid
3 diet Fermented Foods
3 Fucoidan
3 Germanium Organic/Ge-132 / propagermanium (organogermanium)
3 Magnetic Fields
2 Aloe anthraquinones
2 Butyrate
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Cat’s Claw
2 Chlorogenic acid
2 Carica papaya leaf extract
2 Cucurbitacin
2 Date Fruit Extract
2 Docosahexaenoic Acid
2 diet Short Term Fasting
2 Disulfiram
2 doxorubicin
2 EGCG (Epigallocatechin Gallate)
2 Emodin
2 Hydrogen Gas
2 Isobavachalcone
2 Inulin Prebiotic
2 Ivermectin
2 Isovitexin
2 Licochalcone A
2 Magnetic Field Rotating
2 Selenium
2 Selenium NanoParticles
1 5-Aminolevulinic acid
1 Photodynamic Therapy
1 Anethole/trans-Anethole
1 Aspirin
1 Astaxanthin
1 Bevacizumab (brand Avastin)
1 Bromelain
1 Boswellia (frankincense)
1 Black phosphorus
1 Bruteridin(bergamot juice)
1 α-Bisabolol / Chamomile oil
1 Caffeic acid
1 Capsaicin
1 Carvacrol
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Celastrol
1 Chlorophyllin
1 Chocolate
1 Carvone
1 diet FMD Fasting Mimicking Diet
1 D-limonene
1 Copper and Cu NanoParticles
1 flavonoids
1 Ginger/6-Shogaol/Gingerol
1 Ginkgetin
1 Gossypol/AT-101
1 hydroxychloroquine
1 Gemcitabine (Gemzar)
1 Paclitaxel/Taxol
1 Helleborus niger extracts – Christmas Rose
1 Honokiol
1 Indole-3-carbinol
1 iodine
1 metronomic chemo
1 Juglone
1 Kaempferol
1 Lactobacillus
1 probiotics
1 Lapachol
1 Mung Bean Sprouts
1 Vitexin
1 Metformin
1 Neem
1 Nimbolide
1 Peppermint
1 Piperine
1 Thyme
1 Thymol-Thymus vulgaris
1 Urolithin
1 Zerumbone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1332  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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