Cancer Research Results

, aggregation: Click to Expand ⟱
Source:
Type:
Beta-Amyloid (): In Alzheimer’s disease, peptides tend to misfold and aggregate into oligomers and fibrils.


Scientific Papers found: Click to Expand⟱
3232- EGCG,    (−)-Epigallocatechin-3-gallate attenuates cognitive deterioration in Alzheimer׳s disease model mice by upregulating neprilysin expression
- in-vivo, AD, NA
HDAC1↓, *HDAC1↓, *↓, *cognitive↑,
3237- EGCG,    (-)-Epigallocatechin-3-gallate attenuates cognitive deterioration in Alzheimer's disease model mice by upregulating neprilysin expression
- in-vivo, AD, NA
*HDAC↓, *↓, cognitive↑,
3591- EGCG,    Epigallocatechin-3-Gallate Provides Protection Against Alzheimer's Disease-Induced Learning and Memory Impairments in Rats
- in-vivo, AD, NA
*p‑tau↓, *BACE/β-secretase↓, *↓, *Ach↑, *AChE↓, *antiOx↑, *memory↑, *hepatoP↑, *ROS↓, *GPx↑, *SOD↑,
3593- EGCG,    Epigallocatechin Gallate (EGCG)
- Review, AD, NA
AntiTum↑, *Inflam↓, *neuroP↑, *↓, *BioAv↝, cognitive↑,
6784- EGCG,    Dietary (−)-Epigallocatechin Gallate (EGCG): State-of-the-Art Advances in Bioactivities, Bioavailability Enhancement Strategies, and Applications in Nutrition and Health
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiCan↑, *cardioP↑, *neuroP↑, *GutMicro↑, *AntiBio↑, *ROS↓, *TNF-α↓, *IL6↓, TumCP↓, *LDL↓, *NO↓, *Obesity↓, *p‑tau↓, *↓, *NRF2↑, *SOD↑, *Catalase↑, *GPx↑, *NLRP3↓, *mTOR↓, TumCCA↑, NRF2↓, Apoptosis↑, SIRT1↓, miR-25-5p↓, PARP↑, Casp3↑, Casp9↑, ER Stress↑, TumAuto↑, EMT↓, TumCI↓, TumCMig↓, TGF-β↓, Smad1↓, STAT3↓, VEGF↓, angioG↓, Imm↑, EGFR↓, *GutMicro↑, *Bacteria↓, *AntiViral↑, *BioAv↓, *BioAv↑, *eff↑, *BioAv↑, eff↑, ChemoSen↑, *toxicity↝,
6049- EGCG,  SeNPs,    Epigallocatechin-3-gallate (EGCG)-stabilized selenium nanoparticles coated with Tet-1 peptide to reduce amyloid-β aggregation and cytotoxicity
- Study, AD, PC12
*↓, *Dose↝, *BioAv↑, *ROS↓,
6824- EMD,    Neuroprotective, Anti-Inflammatory and Antifibrillogenic Offerings by Emodin against Alzheimer’s Dementia: A Systematic Review
- Review, AD, NA
*Inflam?, *antiOx↑, *tau↓, *↓, *neuroP↑, *ROS↓, *memory↑, *cognitive↑, *other↝, *AChE↓, *BACE/β-secretase↓, *LC3II↓, *Beclin-1/ATG6↓, *p‑tau↓, *CREB↑, *HNE↓, *BioAv↓, *BioAv↝, *BioAv↑, *BioAv↑, *BioAv↑, *BioAv↑, BioAv↑, *HO-1↑, *PKCδ↑, *Akt↑, *NLRP3↓, *NF-kB↓, *TLR3↓,
6816- EMD,    Emodin attenuates Alzheimer's disease by activating the protein kinase C signaling pathway
- in-vivo, AD, NA
*cognitive↑, *↓, *p‑PKCδ↑, *ROS↓,
6817- EMD,    Emodin inhibits aggregation of amyloid-β peptide 1–42 and improves cognitive deficits in Alzheimer's disease transgenic mice
- in-vivo, AD, NA
*↓, *tau↓, *ROS↓, *Inflam↓, *cognitive↑,
6818- EMD,    Emodin Rescued Hyperhomocysteinemia-Induced Dementia and Alzheimer's Disease-Like Features in Rats
- in-vivo, AD, NA
*↓, *p‑tau↓, *PP2A↑, *cAMP↑, *5LO↓, *IL6↓, *TNF-α↓, *ROS↓, *DNMT1↓,
6821- EMD,    Emodin derivatives as promising multi-aspect intervention agents for amyloid aggregation: molecular docking/dynamics simulation, bioactivities evaluation, and cytoprotection
- Study, AD, NA
*ROS↓, *↓,
6822- EMD,    Behavioral, Histopathological, and Biochemical Implications of Aloe Emodin in Copper--Induced Alzheimer's Disease-like Model Rats
- in-vivo, AD, NA
*Copper↓, *↓, *memory↑, *cognitive↑, *Apoptosis↓, *TAC↑, *Inflam↓,
6826- EMD,    Exploring the therapeutic potential of natural compounds for Alzheimer's disease: Mechanisms of action and pharmacological properties
*AntiCan↑, *hepatoP↑, *Inflam↓, *antiOx↑, *Bacteria↓, *↓, *p‑tau↓, *BACE/β-secretase↓, *PP2A↑,
6828- EMD,    Neuroprotective effect of emodin against Alzheimer's disease via Nrf2 signaling in U251 cells and APP/PS1 mice
- in-vitro, AD, U251
*MMP↑, *ROS↓, *NRF2↑, *HO-1↑, *SOD↑, *Bcl-2↑, *Catalase↑, *BAX↓, *memory↑, *ANXi↓, *↓, *antiOx↑, *MDA↓,
3830- EMD,    Traditional Chinese Medicine: Role in Reducing β-Amyloid, Apoptosis, Autophagy, Neuroinflammation, Oxidative Stress, and Mitochondrial Dysfunction of Alzheimer’s Disease
- Review, AD, NA
*neuroP↑, *↓, *p‑tau↓, *BACE/β-secretase↓,
6378- Eug,    Effects of Eugenol on the Central Nervous System: Its Possible Application to Treatment of Alzheimer's Disease, Depression, and Parkinson's Disease
- Review, AD, NA
*other↑, *↓, *BDNF↑, *MAOA↑, *toxicity↓, *Ca+2↓, *antiOx↑, *ROS↓, *lipid-P↓, *neuroP↑, *PGE2↓, *COX2/PTGS2↓, *5LO↓,
6377- Eug,    Pharmacological Properties and Health Benefits of Eugenol: A Comprehensive Review
- Review, Var, NA - Review, AD, NA
*Inflam↓, *Bacteria↓, ChemoSen↑, *selectivity↑, ROS⇅, TumCG↓, MMP↓, antiOx⇅, *antiOx↑, *BBB↑, *neuroP↑, *BDNF↑, *↓, *Ca+2↓, *5LO↓, *MAOA↓, other↑,
4068- FA,    Hyperhomocysteinemia in Alzheimer's disease: the hen and the egg?
- in-vivo, AD, NA
*Hcy/homoC↓, *↓,
4070- FA,    Folic Acid Supplementation Mitigates Alzheimer's Disease by Reducing Inflammation: A Randomized Controlled Trial
- Trial, AD, NA
*cognitive↑, *↓, *TNF-α↓, *Inflam↓,
4071- FA,    Folate and Alzheimer: when time matters
- Review, AD, NA
*cognitive↑, *ROS↓, *Ca+2↓, *p‑tau↓, *↓,
3710- FA,    Therapeutic Potential of Ferulic Acid in Alzheimer's Disease
- Review, AD, NA
*antiOx↑, *AntiCan↑, *Inflam↓, *hepatoP↑, *cardioP↑, *neuroP↑, *↓, *ROS↓, *AChE↓,
3711- FA,    A review on ferulic acid and analogs based scaffolds for the management of Alzheimer's disease
- Review, AD, NA
*antiOx↑, *neuroP↑, *↓, *Inflam↓, *AChE↓, *IronCh↑,
3712- FA,    Ferulic Acid: A Hope for Alzheimer’s Disease Therapy from Plants
- Review, AD, NA
*antiOx↑, *Inflam↓, *ROS↓, *↓, *HO-1↑, *HSP70/HSPA5↑, *ERK↑, *Akt↑, *iNOS↓, *COX2/PTGS2↓, *cardioP↑, *memory↑, *IL2↓, *cognitive↑, *APP↓, *SOD↑, *Catalase↑, *Akt↑, *BioAv↑,
3713- FA,    Protective Effect of Ferulic Acid on Acetylcholinesterase and Amyloid Beta Peptide Plaque Formation in Alzheimer’s Disease: An In Vitro Study
- Review, AD, NA
*AChE↓, *antiOx↑, *neuroP↑, *↓, *MMP↓, *XO↓, *SOD↑, *lipid-P↑, *ROS↓,
3714- FA,    Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer's Disease: A Narrative Review
- Review, AD, NA
*antiOx↑, *Inflam↓, *neuroP↑, *NF-kB↓, *NLRP3↓, *iNOS↓, *COX2/PTGS2↓, *TNF-α↓, *IL1β↓, *VCAM-1↓, *ICAM-1↓, *p‑MAPK↓, *p38↓, *JNK↓, *IL6↓, *IL8↓, *hepatoP↑, *RenoP↑, *Catalase↑, *PPARγ↑, *ROS↓, *Fenton↓, *IronCh↑, *SOD↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *ARE↑, *Bil↑, *radioP↑, *GCLC↑, *GCLM↑, *NQO1↑, *Half-Life↝, *GutMicro↑, *↓, *BDNF↑, *Ca+2↓, *lipid-P↓, *PGE2↓, *cognitive↑, *ChAT↑, *memory↑, *Dose↝, *toxicity↓,
3715- FA,  CUR,  PS,    The Additive Effects of Low Dose Intake of Ferulic Acid, Phosphatidylserine and Curcumin, Not Alone, Improve Cognitive Function in APPswe/PS1dE9 Transgenic Mice
- in-vivo, AD, NA
*cognitive↑, *IL1β↓, *Ach↑, *↓, *p‑tau↓, *BDNF↑, *APP↓,
3717- FA,    Neuroprotective Properties of Ferulic Acid in Preclinical Models of Alzheimer's Disease: A Systematic Literature Review
- Review, AD, NA
*toxicity↓, *BBB↑, *↓, *antiOx↑, *Inflam↓, *neuroP↑,
3783- FA,    Design, Synthesis, and Biological Evaluation of Ferulic Acid-Piperazine Derivatives Targeting Pathological Hallmarks of Alzheimer’s Disease
- NA, AD, NA
*ROS↓, *IronCh↑, *NLRP3↓, *↓, *AChE↓, *BChE↓, *antiOx↑, *BBB↑, *MMP↑, *memory↑, *SOD↑, *Catalase↑,
3782- FA,    Ferulic acid ameliorates bisphenol A (BPA)-induced Alzheimer’s disease-like pathology through Akt-ERK crosstalk pathway in male rats
- in-vivo, AD, NA
*cognitive↑, *ERK↓, *p‑Akt↓, *AChE↓, *BACE/β-secretase↓, *neuroP↑, *ROS↓, *MDA↓, *GSH↑, *GSSG↓, *p‑tau↓, *lipid-P↓, *↓,
3779- FA,    A review on ferulic acid and analogs based scaffolds for the management of Alzheimer’s disease
- Review, AD, NA
*antiOx↑, *neuroP↑, *↓, *Inflam↓, *COX2/PTGS2↓, *Casp↓, *NOS2↓, *HO-1↑, *AChE∅, *BChE∅, *memory↑,
3778- FA,    Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer’s Disease: A Narrative Review
- Review, AD, NA
*neuroP↑, *↓, *antiOx↑, *Inflam↓, *ROS↓, *NF-kB↓, *NLRP3↓, *iNOS↓, *COX2/PTGS2↓, *TNF-α↓, *IL1β↓, *VCAM-1↓, *ICAM-1↓, *p‑MAPK?, *hepatoP↑, *TLR4↓, *PPARγ↑, *NRF2↑, *Fenton↓, *IronCh↑, *MDA↓, *HO-1↑, *Bil↑, *GCLC↑, *GCLM↑, *NQO1↑, *GutMicro↑, *SOD↑, *Ca+2↓, *lipid-P↓, *PGE2↓,
6884- FA,    Effects of folic acid supplementation on cognitive function and -related biomarkers in mild cognitive impairment: a randomized controlled trial
- Trial, AD, NA
*cognitive↑, *↓, *BP↓, *SAM-e↓, *DNMT3A↑,
6867- FA,  Ang,    Effect of Feru-guard 100M on amyloid-beta deposition in individuals with mild cognitive impairment
- Trial, AD, NA
*∅, *BrainVol∅, *cognitive∅,
6866- FA,  Ang,    Effects of Ferulic Acid and Angelica archangelica Extract (Feru-guard ®) on Mild Cognitive Impairment: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Prospective Trial
- Trial, AD, NA
*cognitive↑, *neuroP↑, *AChE↓, *Dose↝, *↓,
6954- FA,    Folic acid as a potential therapeutic agent for Alzheimer's disease: Effects on inflammatory cytokines, amyloid deposition, and neurotransmitter metabolism
- Trial, AD, NA
*Inflam↓, *↓, *IL1β↓, *IL6↓, *TNF-α↓, *tau↓, *GABA↑, *5HT↑, *Ach↑, *Albumin↑, *HemoG↑, *neuroP↑, *Hcy/homoC↓,
7829- FA,  MBS,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*BioAv↑, *cognitive↓, *Dose↝, *neuroP↑, *↓, *BACE/β-secretase↓, *ADAM10↑, *Ac-histone H3↑, *BloodF↑, *IRes↑, *memory↑, *Dose↝,
6913- FIS,    Fisetin inhibits tau aggregation by interacting with the protein and preventing the formation of β-strands
- in-vitro, AD, NA
*↓,
6917- FIS,    Dietary flavonoid fisetin regulates aluminium chloride-induced neuronal apoptosis in cortex and hippocampus of mice brain
- in-vivo, AD, NA - in-vivo, Park, NA
*neuroP↑, *Dose↝, *↓, *ASK1↓, *p‑JNK↓, *P53↓, *Cyt‑c↓, *Casp9↓, *Bax:Bcl2↝,
2861- FIS,    The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress
- Review, Nor, NA - Review, Stroke, NA - Review, Park, NA
*antiOx↑, *ROS↓, *neuroP↑, *NO↑, BioAv↝, *BBB↑, *toxicity↑, *eff↑, *GSH↑, *SOD↑, *↓, *12LOX↓, *COX2/PTGS2↓, *Catalase↑, *Inflam↓, *TNF-α↓, *IL6↑, *lipid-P↓, NF-kB↓, IL1β↓, NRF2↑, HO-1↑, GSTs↑, cognitive↑, *BDNF↑,
6923- Flav,    Flavonoids: an overview
- Review, Nor, NA
*antiOx↑, AntiCan↑, *cardioP↑, *XO↓, *COX2/PTGS2↓, *5LO↓, *PI3K↓, *AChE↓, *Imm⇅, *BP↓, TumCCA↑, *↓, *BACE/β-secretase↓, *NF-kB↓, *ROS↓, *neuroP↑, *AntiAg↑, *AntiThr↑,
4107- FLS,  Ex,    Combined effects of aerobic exercise and 40-Hz light flicker exposure on early cognitive impairments in Alzheimer's disease of 3×Tg mice
- in-vivo, AD, NA
*↓, *cognitive↑, *Inflam↓, *eff↑,
6929- FLS,  AudGS,    Multisensory gamma stimulation promotes glymphatic clearance of amyloid
- in-vivo, AD, NA
*pol-AQPs↑, *↓, *GlyFlow↑,
6931- FLS,    Gamma frequency sensory stimulation in mild probable Alzheimer's dementia patients: Results of feasibility and pilot studies
- Trial, AD, NA
*tau↓, *↓, *other↝, *other↑, *memory↑, *other↑,
7016- Fuc,    Therapies from Fucoidan: New Developments
- Review, Var, NA
*Bacteria↓, *BioAv↓, *Dose↝, *GutMicro↑, PD-1↝, ROS⇅, cl‑Casp↑, cl‑PARP↑, RadioS↑, *radioP↑, *neuroP↑, *↓,
4018- FulvicA,  Fe,    Inhibitory Impacts of Fulvic Acid-Coated Iron Oxide Nanoparticles on the Amyloid Fibril Aggregations
- in-vivo, AD, NA
*Inflam↓, *↓,
7833- GA,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*neuroP↑, *Dose↝, *ADAM10↝, *BACE/β-secretase↓, *cl‑APP↓, *↓, *Ca+2↓, *ROS↓, *NeuroI↓,
7212- GBE,    The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease
- Review, AD, NA
*antiOx↑, *ROS↓, *mitResp↑, *Casp9↓, *Casp3↓, *Apoptosis↓, *ATP↑, *neuroP↑, *IL1β↓, *IL6↓, *TNF-α↓, *PGE2↓, *memory↑, *cognitive↑, *BloodF↑, *lipid-P↓, *↓, *MAOA↓, *DA↑, *Dose↝, *toxicity↓,
3723- GBE,    Can We Use Ginkgo biloba Extract to Treat Alzheimer’s Disease? Lessons from Preclinical and Clinical Studies
- Review, AD, NA
*memory↑, *antiOx↑, *Casp3↓, *APP↓, *AChE↓, *↓, *5HT↑, *SOD↓, *MDA↓, *NO↓, *GSH↑, *Bcl-2↑, *BAX↑, *TNF-α↓, *IL1β↑, *iNOS↓, *IL10↓, *p‑tau↓, *ROS↓, *MAOB↓, *cognitive↑, *neuroP↑, *Apoptosis↓,
7278- GGB,    Ginkgolide B: mechanisms of neurobiological effects, prospects for use in the therapy of Alzheimer's disease
- Review, AD, NA
*neuroP↑, *↓, *BDNF↑, *cognitive↑, *memory↑,
7251- Gink,    Ginkgetin: A Promising Multitarget Agent for Diverse Diseases
- Review, Var, NA
*Inflam↓, *antiOx↓, AntiCan↑, *neuroP↑, *cardioP↑, *Bacteria↓, *ROS↓, *lipid-P↓, *NRF2↓, *Keap1↓, *NF-kB↓, *MAPK↓, MMP2↓, M2 MC↓, JAK2↓, STAT3↓, TumCP↓, Casp↑, ChemoSen↑, *BMD↑, *↓, *Stroke↓, *BioAv↓,

Showing Research Papers: 101 to 150 of 334
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 334

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1)

antiOx⇅, 1,   GSTs↑, 1,   HO-1↑, 1,   NRF2↓, 1,   NRF2↑, 1,   ROS⇅, 2,  

Mitochondria & Bioenergetics(tgid=3)

MMP↓, 1,  

Core Metabolism/Glycolysis(tgid=4)

SIRT1↓, 1,  

Cell Death(tgid=5)

Apoptosis↑, 1,   Casp↑, 1,   cl‑Casp↑, 1,   Casp3↑, 1,   Casp9↑, 1,  

Kinase & Signal Transduction(tgid=6)

miR-25-5p↓, 1,  

Transcription & Epigenetics(tgid=7)

other↑, 1,  

Protein Folding & ER Stress(tgid=8)

ER Stress↑, 1,  

Autophagy & Lysosomes(tgid=9)

TumAuto↑, 1,  

DNA Damage & Repair(tgid=10)

PARP↑, 1,   cl‑PARP↑, 1,  

Cell Cycle & Senescence(tgid=11)

TumCCA↑, 2,  

Proliferation, Differentiation & Cell State(tgid=12)

EMT↓, 1,   HDAC1↓, 1,   STAT3↓, 2,   TumCG↓, 1,  

Migration(tgid=13)

MMP2↓, 1,   Smad1↓, 1,   TGF-β↓, 1,   TumCI↓, 1,   TumCMig↓, 1,   TumCP↓, 2,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 1,   EGFR↓, 1,   VEGF↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

IL1β↓, 1,   Imm↑, 1,   JAK2↓, 1,   M2 MC↓, 1,   NF-kB↓, 1,   PD-1↝, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↑, 1,   BioAv↝, 1,   ChemoSen↑, 3,   eff↑, 1,   RadioS↑, 1,  

Clinical Biomarkers(tgid=22)

EGFR↓, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 2,   AntiTum↑, 1,   cognitive↑, 3,  
Total Targets: 48

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0)

AntiBio↑, 1,   DA↑, 1,   GlyFlow↑, 1,   IRes↑, 1,   NeuroI↓, 1,   Stroke↓, 1,  

Redox & Oxidative Stress(tgid=1)

antiOx↓, 1,   antiOx↑, 20,   ARE↑, 1,   Bil↑, 2,   Catalase↑, 6,   Copper↓, 1,   Fenton↓, 2,   GCLC↑, 2,   GCLM↑, 2,   GPx↑, 2,   GSH↑, 3,   GSSG↓, 1,   HNE↓, 1,   HO-1↑, 6,   Keap1↓, 1,   lipid-P↓, 8,   lipid-P↑, 1,   MDA↓, 5,   NQO1↑, 2,   NRF2↓, 1,   NRF2↑, 4,   ROS↓, 24,   SAM-e↓, 1,   SOD↓, 1,   SOD↑, 9,   TAC↑, 1,  

Metal & Cofactor Biology(tgid=2)

IronCh↑, 4,  

Mitochondria & Bioenergetics(tgid=3)

ATP↑, 1,   mitResp↑, 1,   MMP↓, 1,   MMP↑, 2,  

Core Metabolism/Glycolysis(tgid=4)

12LOX↓, 1,   Ac-histone H3↑, 1,   cAMP↑, 1,   CREB↑, 1,   LDL↓, 1,   PPARγ↑, 2,  

Cell Death(tgid=5)

Akt↑, 3,   p‑Akt↓, 1,   Apoptosis↓, 3,   ASK1↓, 1,   BAX↓, 1,   BAX↑, 1,   Bax:Bcl2↝, 1,   Bcl-2↑, 2,   Casp↓, 1,   Casp3↓, 2,   Casp9↓, 2,   Cyt‑c↓, 1,   iNOS↓, 4,   JNK↓, 1,   p‑JNK↓, 1,   MAPK↓, 1,   p‑MAPK?, 1,   p‑MAPK↓, 1,   p38↓, 1,  

Transcription & Epigenetics(tgid=7)

Ach↑, 3,   AntiThr↑, 1,   other↑, 3,   other↝, 2,  

Protein Folding & ER Stress(tgid=8)

HSP70/HSPA5↑, 1,  

Autophagy & Lysosomes(tgid=9)

Beclin-1/ATG6↓, 1,   LC3II↓, 1,  

DNA Damage & Repair(tgid=10)

DNMT1↓, 1,   DNMT3A↑, 1,   P53↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

ERK↓, 1,   ERK↑, 1,   HDAC↓, 1,   HDAC1↓, 1,   mTOR↓, 1,   PI3K↓, 1,  

Migration(tgid=13)

5LO↓, 4,   AntiAg↑, 1,   APP↓, 3,   cl‑APP↓, 1,   Ca+2↓, 6,   PKCδ↑, 1,   p‑PKCδ↑, 1,   VCAM-1↓, 2,  

Angiogenesis & Vasculature(tgid=14)

NO↓, 2,   NO↑, 1,  

Barriers & Transport(tgid=15)

pol-AQPs↑, 1,   BBB↑, 4,  

Immune & Inflammatory Signaling(tgid=16)

COX2/PTGS2↓, 7,   ICAM-1↓, 2,   IL10↓, 1,   IL1β↓, 5,   IL1β↑, 1,   IL2↓, 1,   IL6↓, 5,   IL6↑, 1,   IL8↓, 1,   Imm⇅, 1,   Inflam?, 1,   Inflam↓, 19,   NF-kB↓, 5,   PGE2↓, 4,   TLR3↓, 1,   TLR4↓, 1,   TNF-α↓, 9,  

Synaptic & Neurotransmission(tgid=18)

5HT↑, 2,   AChE↓, 10,   AChE∅, 1,   ADAM10↑, 1,   ADAM10↝, 1,   BChE↓, 1,   BChE∅, 1,   BDNF↑, 6,   BrainVol∅, 1,   ChAT↑, 1,   GABA↑, 1,   MAOA↓, 2,   MAOA↑, 1,   tau↓, 4,   p‑tau↓, 10,  

Protein Aggregation(tgid=19)

↓, 49,   ∅, 1,   BACE/β-secretase↓, 8,   MAOB↓, 1,   NLRP3↓, 5,   PP2A↑, 2,   XO↓, 2,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 4,   BioAv↑, 9,   BioAv↝, 2,   Dose↝, 9,   eff↑, 3,   Half-Life↝, 1,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22)

Albumin↑, 1,   Bil↑, 2,   BloodF↑, 2,   BMD↑, 1,   BP↓, 2,   GutMicro↑, 5,   Hcy/homoC↓, 2,   HemoG↑, 1,   IL6↓, 5,   IL6↑, 1,   NOS2↓, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 3,   ANXi↓, 1,   cardioP↑, 5,   cognitive↓, 1,   cognitive↑, 17,   cognitive∅, 1,   hepatoP↑, 5,   memory↑, 13,   neuroP↑, 26,   Obesity↓, 1,   radioP↑, 2,   RenoP↑, 1,   toxicity↓, 4,   toxicity↑, 1,   toxicity↝, 1,  

Infection & Microbiome(tgid=24)

AntiViral↑, 1,   Bacteria↓, 5,  
Total Targets: 164

Scientific Paper Hit Count for: , aggregation
19 Selenium NanoParticles
17 Curcumin
14 Resveratrol
14 Ferulic acid
14 Urolithin
12 Magnetic Fields
9 EGCG (Epigallocatechin Gallate)
9 Emodin
8 Berberine
8 Chlorogenic acid
8 Thymoquinone
7 Alpha-Lipoic-Acid
7 Mung Bean Sprouts
7 Hydrogen Gas
7 Quercetin
7 Rosmarinic acid
6 Rutin
6 Folic Acid, Vit B9
6 EMF
5 isoquercitrin
5 Ashwagandha(Withaferin A)
5 Carnosine
5 Crocetin
5 Magnetic Field Rotating
5 Mushroom Lion’s Mane
5 Sulforaphane (mainly Broccoli)
4 Apigenin (mainly Parsley)
4 Capsaicin
4 Cinnamon
4 Ginseng
4 Hyperoside
4 Luteolin
4 Silymarin (Milk Thistle) silibinin
4 Vitamin B1/Thiamine
3 beta-carotene(VitA)
3 Cichoric acid / Chicoric acid
3 Fisetin
3 Flickering Light Stimulation
3 Honokiol
3 HydroxyTyrosol
3 isoorientin
3 Kaempferol
3 Licochalcone A
3 Radio Frequency
3 Vitamin B3,Niacin
3 Vitamin B5,Pantothenic Acid
3 Vitamin D3
3 Vitamin K2
2 Aromatherapy
2 Huperzine A/Huperzia serrata
2 Bacopa monnieri
2 borneol
2 Boron
2 Boswellia (frankincense)
2 α-Bisabolol / Chamomile oil
2 Caffeic acid
2 Centella asiatica / Gotu kola → asiaticoside
2 Choline
2 Echinacea
2 Vitamin E
2 diet Short Term Fasting
2 D-limonene
2 Eugenol
2 Angelica archangelica / Garden Angelica
2 Ginkgo biloba
2 Ginkgetin
2 hydrogen sulfide
2 Isobavachalcone
2 Isovitexin
2 MCToil
2 Moringa oleifera
2 chitosan
2 Taurine
1 1,8-Cineole
1 Annona atemoya Leaf Extract
1 Anthocyanins
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Astaxanthin
1 Carnosic acid
1 Celastrol
1 Chrysin
1 Coenzyme Q10
1 Rivastigmine
1 Galantamine
1 Cysteamine
1 Date Fruit Extract
1 diet Fermented Foods
1 Ginkgo biloba-EGb 761
1 Phosphatidylserine
1 flavonoids
1 Exercise
1 Auditory Gamma Stimulation / 40 Hz Auditory Stimulation
1 Fucoidan
1 Shilajit/Fulvic Acid
1 Iron
1 Gallic acid
1 Ginkgolide B
1 Oleuropein
1 Isoliquiritigenin
1 isoflavones
1 Morin
1 Lutein
1 Zeaxanthin
1 Lycopene
1 Vitexin
1 Methylsulfonylmethane
1 Myricetin
1 Nimbolide
1 Protocatechuic acid
1 Piperine
1 Piperlongumine
1 Salvia officinalis
1 S-adenosyl-L-methionine
1 Carvacrol
1 Sesame seeds and Oil
1 Silicic Acid
1 Spermidine
1 Ursolic acid
1 Vanillic Acid
1 Vitamin A, Retinoic Acid
1 Vitamin B12
1 Vitamin B2,Riboflavin
1 probiotics
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1333  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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