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| Risk: by definition reduces risk of disease or cancer. Down Target direction of risk indicates lower cancer risk. ChemoPreventive also mean lower cancer risk. But for Chemopreventive an up arrow indicates more preventive.
Cancer Risk Impact Score (CRIS)
CRIS scale:
–5 = very strong risk reduction
–4 = strong risk reduction
–3 = moderate risk reduction
–2 = modest risk reduction
–1 = weak / context-dependent
0 = neutral
|
| 2852- | FIS, | A comprehensive view on the fisetin impact on colorectal cancer in animal models: Focusing on cellular and molecular mechanisms |
| - | Review, | CRC, | NA |
| 2172- | iod, | A prospective study of iodine status, thyroid function, and prostate cancer risk: follow-up of the First National Health and Nutrition Examination Survey |
| - | Study, | Pca, | NA |
| 4010- | K+, | Potassium-sparing diuretics might reduce risk of Alzheimer's disease |
| - | Review, | AD, | NA |
| 4005- | K+, | Potassium |
| - | Review, | Nor, | NA | - | Review, | Stroke, | NA |
| 1789- | LEC, | Risk.33.aspx">Lecithin Supplements and Breast Cancer Risk |
| - | Analysis, | NA, | NA |
| 4195- | Lut, | Zeax, | Low Xanthophylls, Retinol, Lycopene, and Tocopherols in Grey and White Matter of Brains with Alzheimer’s Disease |
| - | Human, | AD, | NA |
| 3816- | Lyco, | Lut, | Zeax, | Serum lycopene, lutein and zeaxanthin, and the risk of Alzheimer's disease mortality in older adults |
| - | Review, | AD, | NA |
| 4786- | Lyco, | Anti-proliferative and apoptosis-inducing activity of lycopene against three subtypes of human breast cancer cell lines |
| - | in-vitro, | BC, | MDA-MB-468 | - | in-vitro, | BC, | MCF-7 | - | in-vitro, | BC, | SkBr3 |
| 4791- | Lyco, | Investigating into anti-cancer potential of lycopene: Molecular targets |
| - | Review, | Var, | NA |
| 4799- | Lyco, | Anticancer Properties of Lycopene |
| - | Review, | Var, | NA |
| - | Review, | Var, | NA |
| 4797- | Lyco, | A mechanistic updated overview on lycopene as potential anticancer agent |
| - | Review, | Var, | NA |
| 4796- | Lyco, | The Anti-proliferation Effects of Lycopene on Breast Cancer Cells |
| - | in-vitro, | BC, | MCF-7 | - | in-vitro, | Nor, | MCF10 |
| 4793- | Lyco, | Lycopene treatment inhibits activation of Jak1/Stat3 and Wnt/β-catenin signaling and attenuates hyperproliferation in gastric epithelial cells |
| - | in-vitro, | GC, | AGS |
| 4792- | Lyco, | A Comprehensive Review on the Molecular Mechanism of Lycopene in Cancer Therapy |
| - | Review, | Var, | NA |
| 1786- | MEL, | What is known about melatonin, chemotherapy and altered gene expression in breast cancer (Review) |
| - | Review, | NA, | NA |
| 1779- | MEL, | Therapeutic Potential of Melatonin Counteracting Chemotherapy-Induced Toxicity in Breast Cancer Patients: A Systematic Review |
| - | Review, | BC, | NA |
| 5785- | MET, | Metformin improves healthspan and lifespan in mice |
| - | in-vivo, | Nor, | NA |
| 5796- | MET, | Tumor, whole blood, plasma, and tissue concentrations of metformin in lung cancer patients |
| - | Human, | Lung, | NA |
| 5795- | MET, | Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes |
| - | Review, | AD, | NA | - | Review, | Park, | NA | - | Review, | Diabetic, | NA |
| 769- | Mg, | Magnesium and cancer: more questions than answers |
| - | Review, | NA, | NA |
| 770- | Mg, | Magnesium and cancer: a dangerous liason |
| - | Analysis, | NA, | NA |
| 783- | Mg, | Magnesium intake and incidence of pancreatic cancer: the VITamins and Lifestyle study |
| 784- | Mg, | Direct and indirect associations between dietary magnesium intake and breast cancer risk |
| - | Analysis, | NA, | NA |
| 785- | Mg, | Magnesium: The overlooked electrolyte in blood cancers? |
| - | Analysis, | NA, | NA |
| 786- | Mg, | VitC, | A narrative review on the role of magnesium in immune regulation, inflammation, infectious diseases, and cancer |
| 4626- | OLE, | A Comprehensive Review on the Anti-Cancer Effects of Oleuropein |
| - | Review, | Var, | NA |
| 4921- | PEITC, | The Potential Use of Phenethyl Isothiocyanate for Cancer Prevention |
| - | Review, | Var, | NA |
| 4922- | PEITC, | Phenethyl Isothiocyanate: A comprehensive review of anti-cancer mechanisms |
| - | Review, | Var, | NA |
| 4928- | PEITC, | Dietary phytochemical PEITC restricts tumor development via modulation of epigenetic writers and erasers |
| - | vitro+vivo, | Colon, | SW-620 |
| 4931- | PEITC, | Phenethyl isothiocyanate (PEITC) suppresses prostate cancer cell invasion epigenetically through regulating microRNA-194 |
| - | in-vitro, | Pca, | LNCaP | - | in-vitro, | Pca, | PC3 |
| 4938- | PEITC, | Clinical Trial of 2-Phenethyl Isothiocyanate as an Inhibitor of Metabolic Activation of a Tobacco-Specific Lung Carcinogen in Cigarette Smokers |
| - | Trial, | Nor, | NA |
| 4939- | PEITC, | Phenethyl Isothiocyanate Inhibits Angiogenesis In vitro and Ex vivo |
| - | in-vitro, | Pca, | PC3 | - | ex-vivo, | Nor, | HUVECs |
| 911- | QC, | SFN, | Pilot study evaluating broccoli sprouts in advanced pancreatic cancer (POUDER trial) - study protocol for a randomized controlled trial |
| 2141- | Se, | Selenium and cancer risk: Wide-angled Mendelian randomization analysis |
| - | Review, | NA, | NA |
| 2140- | Se, | Selenium Exposure and Cancer Risk: an Updated Meta-analysis and Meta-regression |
| - | Review, | Var, | NA |
| 2142- | Se, | A U-shaped association between selenium intake and cancer risk |
| - | Review, | NA, | NA |
| 1695- | Se, | Serum Selenium Concentration as a Potential Diagnostic Marker for Early-Stage Colorectal Cancer: A Comparative Study |
| - | Trial, | CRC, | NA |
| 1691- | Se, | The influence of selenium and selenoprotein gene variants on colorectal cancer risk |
| - | Analysis, | CRC, | NA |
| 1692- | Se, | Association of Selenoprotein and Selenium Pathway Genotypes with Risk of Colorectal Cancer and Interaction with Selenium Status |
| - | Analysis, | CRC, | NA |
| 1693- | Se, | Prediagnostic selenium status, selenoprotein gene variants and association with breast cancer risk in a European cohort study |
| - | Analysis, | BC, | NA |
| 1704- | Se, | Prospective study of toenail selenium levels and cancer among women |
| - | Study, | Var, | NA |
| 1703- | Se, | An Assessment of Serum Selenium Concentration in Women with Endometrial Cancer |
| - | Study, | EC, | NA |
| 1702- | Se, | Supplemental Selenium May Decrease Ovarian Cancer Risk in African-American Women |
| - | Human, | Ovarian, | NA |
| 1701- | Se, | An Assessment of Serum Selenium Concentration in Women with Ovarian Cancer |
| - | Human, | Ovarian, | NA |
| 1700- | Se, | Metabolism of Selenium, Selenocysteine, and Selenoproteins in Ferroptosis in Solid Tumor Cancers |
| - | Review, | Var, | NA |
| 1698- | Se, | Association between Dietary Zinc and Selenium Intake, Oxidative Stress-Related Gene Polymorphism, and Colorectal Cancer Risk in Chinese Population - A Case-Control Study |
| - | Human, | CRC, | NA |
| 4485- | Se, | Selenium stimulates the antitumour immunity: Insights to future research |
| - | Review, | NA, | NA |
| 4486- | Se, | Chit, | Selenium-Modified Chitosan Induces HepG2 Cell Apoptosis and Differential Protein Analysis |
| - | in-vitro, | Liver, | HepG2 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:785 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid