AntiCan Cancer Research Results

AntiCan, Anticancer Effect: Click to Expand ⟱
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Anticancer Effect


Scientific Papers found: Click to Expand⟱
4481- Chit,    Antioxidant Properties and Redox-Modulating Activity of Chitosan and Its Derivatives: Biomaterials with Application in Cancer Therapy
- Review, Var, NA
*BioAv↑, *toxicity↓, *antiOx↑, AntiCan↑, *Inflam↓, *ROS↓, *lipid-P↓, MDA↓, selectivity↑, MMP↓, ROS↑, TumCCA↑, MDA↑, GSH↓, ChemoSen↑,
6072- CHL,    Low-dose dietary chlorophyll inhibits multi-organ carcinogenesis in the rainbow trout
- in-vivo, Var, NA
AntiCan↑, AntiTum↑, chemoPv↑,
6081- CHL,    Enhancing Health Benefits through Chlorophylls and Chlorophyll-Rich Agro-Food: A Comprehensive Review
- Review, Nor, NA
*antiOx↑, *toxicity↓, *BioAv↓, *BioAv↑, *neuroP↑, *Obesity↓, *AntiCan↑, *TumCP↓, *PhotoS↑, *neuroP↑,
2780- CHr,    Anti-cancer Activity of Chrysin in Cancer Therapy: a Systematic Review
- Review, Var, NA
*antiOx↑, Inflam↓, *hepatoP↑, AntiCan↑, Cyt‑c↑, Casp3↑, XIAP↓, p‑Akt↓, PI3K↑, Apoptosis↑, COX2↓, FAK↓, AMPK↑, STAT3↑, MMP↓, DNAdam↑, BAX↑, Bak↑, Casp9↑, p38↑, MAPK↑, TumCCA↑, ChemoSen↑, HDAC8↓, Wnt↓, NF-kB↓, angioG↓, BioAv↓,
4762- CoQ10,    The role of coenzyme Q10 as a preventive and therapeutic agent for the treatment of cancers
- Review, Var, NA
*AntiCan↓, *ROS↓, chemoPv↑, TumCCA↑, Apoptosis↑, TumCP↓, angioG↓, MMPs↓, ChemoSen∅,
4768- CoQ10,    Role of coenzymes in cancer metabolism
- Review, Var, NA
Risk↓, *ROS↓, AntiCan↑, TumMeta↓, ROS↑, TumCG↓, Apoptosis↑, TumMeta↓, Wnt↓, β-catenin/ZEB1↓, TumCG↓, selectivity↑, RadioS↑, ChemoSen↑, H2O2↓, MMP2↓, cardioP↑, ChemoSen∅, Dose↝,
4776- CoQ10,    Antitumor properties of Coenzyme Q0 against human ovarian carcinoma cells via induction of ROS-mediated apoptosis and cytoprotective autophagy
- vitro+vivo, Ovarian, SKOV3
ROS↑, eff↓, AntiCan↑, Apoptosis↑, tumCV↓, TumCG↓, TumCCA↑, LC3s↑, ERStress↑, Beclin-1↑, Bax:Bcl2↑, HER2/EBBR2↓, Akt↓, mTOR↓,
5810- CPT,  CPT-11,    Camptothein-Based Anti-Cancer Therapies and Strategies to Improve Their Therapeutic Index
- Review, NA, NA
AntiCan↑, BioAv↓, toxicity⇅, TOP1↓, Apoptosis↑, TumCP↓, other↝, BioAv↑, other↝, eff↑,
5808- CPT,    Repair of Topoisomerase I-Mediated DNA Damage
- Review, Var, NA
TOP1↓, AntiCan↑, Dose?, CHK1↑, Chk2↑,
5780- CRMs,  HCAs,  RES,  Sper,  ASA  Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential
- Review, Var, NA
*OS↑, *AntiAge↑, *cardioP↑, *neuroP↑, AntiCan↑, *TNF-α↓, *Weight↓, *BP↓, *Inflam↓, *Insulin↓, *ROS↓, *AMPK↑, *mTOR↓, *SIRT1↑, CRM↑,
4654- CUR,    Stem Cell Therapy: Curcumin Does the Trick
- Review, Var, NA
*antiOx↑, *Inflam↓, AntiCan↑, chemoPv↑, *AntiAge↑, *neuroP↑, *Wound Healing↑,
4673- CUR,    Curcumin and colorectal cancer: An update and current perspective on this natural medicine
- Review, CRC, NA
AntiCan↑, GutMicro↝,
4708- CUR,    Molecular mechanisms underlying curcumin-mediated microRNA regulation in carcinogenesis; Focused on gastrointestinal cancers
- Review, GC, NA
chemoPv↑, AntiCan↑, *antiOx↑, *Inflam↓, miR-21↓, miR-34a↑, miR-200b↑, miR-27a-3p↓,
2814- CUR,    Curcumin in Cancer and Inflammation: An In-Depth Exploration of Molecular Interactions, Therapeutic Potentials, and the Role in Disease Management
- Review, Var, NA
*BioAv↓, *Inflam↓, *antiOx↑, AntiCan↑, CK2↓, GSK‐3β↓, EGFR↓, TOP1↓, TOP2↓, NF-kB↓, COX2↓, CRP↓,
1875- DCA,    Dichloroacetate inhibits neuroblastoma growth by specifically acting against malignant undifferentiated cells
- in-vitro, neuroblastoma, NA - in-vivo, NA, NA
selectivity↑, AntiCan↑, TumVol↓, PDKs↓, mt-OXPHOS↑, MMP↓, Glycolysis↓, toxicity↓, Warburg↓, ROS↑, eff↑,
1865- DCA,    Reversal of the glycolytic phenotype by dichloroacetate inhibits metastatic breast cancer cell growth in vitro and in vivo
- in-vivo, BC, NA - in-vitro, BC, MCF-7 - in-vitro, BC, T47D
TumCG↓, TumCP↓, AntiCan↑,
1841- dietFMD,    Fasting-Mimicking Diet Is Safe and Reshapes Metabolism and Antitumor Immunity in Patients with Cancer
- Trial, Var, NA
BG↓, AntiCan↑, IFN-γ↑, eff↑, Dose↝, CD14↓, IGF-1↓, IGFR↓, CD8+↑, NK cell↑,
2263- dietMet,    Methionine Restriction and Cancer Biology
- Review, Var, NA
AntiCan↑, TumCP↓, TumCG↓, selectivity↑, ChemoSen↓, RadioS↑, Insulin↓, *GlucoseCon↑, *ROS↓, *antiOx↑, *GSH↑, GSH↑, eff↑, polyA↓, TS↓, Raf↓, Akt↓, Casp9↑, Bak↑, P21↑, p27↑, Insulin↓, IGF-1↓,
2155- dietP,    Transepithelial Anti-Neuroblastoma Response to Kale among Four Vegetable Juices Using In Vitro Model Co-Culture System
- in-vivo, neuroblastoma, Caco-2 - NA, NA, SH-SY5Y
AntiCan↑, ROS↑, eff↑, eff↑, eff↑,
4253- EA,    The effects of Ellagic acid supplementation on neurotrophic, inflammation, and oxidative stress factors, and indoleamine 2, 3-dioxygenase gene expression in multiple sclerosis patients with mild to moderate depressive symptoms: A randomized, triple-blind, placebo-controlled trial
- Human, MS, NA - NA, IBD, NA
*Mood↑, *BDNF↑, *5HT↑, *antiOx↑, *Inflam↓, *AntiCan↑, *QoL↑, *neuroP↑, *cognitive↑, *memory↑,
4832- EA,    Experimental Evidence of the Antitumor, Antimetastatic and Antiangiogenic Activity of Ellagic Acid
*antiOx↑, *AntiCan↑, TumCMig↓, angioG↓, ChemoSen↑, RadioS↑, *chemoP↑, *BioAv↓, eff↓, selectivity↑, MMP2↓, MMP9↓, VEGF↓, TumCCA↑, Apoptosis↑, ROS↑, BioAv↑,
1621- EA,    The multifaceted mechanisms of ellagic acid in the treatment of tumors: State-of-the-art
- Review, Var, NA
AntiCan↑, Apoptosis↑, TumCP↓, TumMeta↓, TumCI↓, TumAuto↑, VEGFR2↓, MAPK↓, PI3K↓, Akt↓, PD-1↓, NOTCH↓, PCNA↓, Ki-67↓, cycD1/CCND1↓, CDK2↑, CDK6↓, Bcl-2↓, cl‑PARP↑, BAX↑, Casp3↑, DR4↑, DR5↑, Snail↓, MMP2↓, MMP9↓, TGF-β↑, PKCδ↓, β-catenin/ZEB1↓, SIRT1↓, HO-1↓, ROS↑, CHOP↑, Cyt‑c↑, MMP↓, OCR↓, AMPK↑, Hif1a↓, NF-kB↓, E-cadherin↑, Vim↓, EMT↓, LC3II↑, CIP2A↓, GLUT1↓, PDH↝, MAD↓, LDH↓, GSTs↑, NOTCH↓, survivin↓, XIAP↓, ER Stress↑, ChemoSideEff↓, ChemoSen↑,
3201- EGCG,    Epigallocatechin Gallate (EGCG): Pharmacological Properties, Biological Activities and Therapeutic Potential
- Review, NA, NA
*AntiCan↑, *cardioP↑, *neuroP↑, *BioAv↝, *BioAv↓, *BioAv↓, *Dose↝, *Half-Life↝, *BioAv↑, *BBB↑, *hepatoP↓, *other↓, *Inflam↓, *NF-kB↓, *AP-1↓, *iNOS↓, *COX2↓, *ROS↓, *RNS↓, *IL8↓, *JAK↓, *PDGFR-BB↓, *IGF-1R↓, *MMP2↓, *P53↓, *NRF2↑, *TNF-α↓, *IL6↓, *E2Fs↑, *SOD1↑, *SOD2↑, Casp3↑, Cyt‑c↑, PARP↑, DNMTs↓, Telomerase↓, Hif1a↓, MMPs↓, BAX↑, Bak↑, Bcl-2↓, Bcl-xL↓, P53↑, PTEN↑, TumCP↓, MAPK↓, HGF/c-Met↓, TIMP1↑, HDAC↓, MMP9↓, uPA↓, GlutMet↓, ChemoSen↑, chemoP↑,
5522- EP,    Nanosecond pulsed electric field suppresses growth and reduces multi-drug resistance effect in pancreatic cancer
- in-vitro, PC, NA
AntiCan↑, Dose↝, CellMemb↑, ChemoSen↑, MMP↓,
1654- FA,    Molecular mechanism of ferulic acid and its derivatives in tumor progression
- Review, Var, NA
AntiCan↑, Inflam↓, RadioS↑, ROS↑, Apoptosis↑, TumCCA↑, TumCMig↑, TumCI↓, angioG↓, ChemoSen↑, ChemoSideEff↓, P53↑, cycD1/CCND1↓, CDK4↓, CDK6↓, TumW↓, miR-34a↑, Bcl-2↓, Casp3↑, BAX↑, β-catenin/ZEB1↓, cMyc↓, Bax:Bcl2↑, SOD↓, GSH↓, LDH↓, ERK↑, eff↑, JAK2↓, STAT6↓, NF-kB↓, PYCR1↓, PI3K↓, Akt↓, mTOR↓, Ki-67↓, VEGF↓, FGFR1↓, EMT↓, CAIX↓, LC3II↑, p62↑, PKM2↓, Glycolysis↓, *BioAv↓,
3710- FA,    Therapeutic Potential of Ferulic Acid in Alzheimer's Disease
- Review, AD, NA
*antiOx↑, *AntiCan↑, *Inflam↓, *hepatoP↑, *cardioP↑, *neuroP↑, *Aβ↓, *ROS↓, *AChE↓,
1773- GA,    Impact of Gallic Acid on Gut Health: Focus on the Gut Microbiome, Immune Response, and Mechanisms of Action
- Review, Var, NA
antiOx↑, AntiCan↑, Inflam↑, GutMicro↑, BioAv↝, BioAv↓, BioAv↑, TumMeta↓,
5152- GamB,    Gambogic Acid as a Candidate for Cancer Therapy: A Review
- Review, Var, NA
AntiCan↑, Apoptosis↑, TumAuto↑, TumCCA↑, TumCI↓, TumMeta↓, angioG↓, eff↑, NF-kB↓, P53↑, P21↑, MDM2↓, HSP90↓, Bcl-2↓, Cyt‑c↑, Casp↑, MMP↓, Casp3↑, Casp9↑, cl‑PARP↑, Bax:Bcl2↑, ROS↑, SIRT1↓, TrxR1↓, Fas↓, FasL↑, FADD↑, APAF1↑, DNAdam↑, NF-kB↓, STAT3↓, MAPK↓, cFos↓, EGFR↓, Akt↓, mTOR↓, AMPK↑, TumCCA↑, ChemoSen↑, P-gp↓, survivin↓,
5148- GamB,    Gambogic acid: A shining natural compound to nanomedicine for cancer therapeutics
- Review, Var, NA
AntiCan↑, angioG↓, ChemoSen↑, RadioS↑, VEGF↓, MMP2↓, MMP9↓, Telomerase↓, TrxR↓, ERK↓, HSP90↓, ROS↑, SIRT1↑, survivin↓, cFLIP↓, Casp3↑, Casp8↑, Casp9↑, BAD↓, BID↓, Bcl-2↓, BAX↑, STAT3↓, hTERT/TERT↓, NF-kB↓, Myc↓, Hif1a↓, FOXD3↑, BioAv↓, BioAv↑, P53↑, eff↓, OCR↓, MMP↓, PI3K↓, Akt↓, BBB↑, TumCG↓, TumMeta↓, BioAv↑,
1957- GamB,    Nanoscale Features of Gambogic Acid Induced ROS-Dependent Apoptosis in Esophageal Cancer Cells Imaged by Atomic Force Microscopy
- in-vitro, ESCC, EC9706
AntiCan↑, toxicity↓, TumCP↓, Apoptosis↑, TumCCA↑, MMP↓, ROS↑, eff↓, RadioS↑,
1958- GamB,    Gambogenic acid induces apoptosis and autophagy through ROS-mediated endoplasmic reticulum stress via JNK pathway in prostate cancer cells
- in-vitro, Pca, NA - in-vivo, NA, NA
AntiCan↑, TumCP↓, TumAuto↑, eff↑, JNK↑, ROS↑, ER Stress↑, eff↓, TumCG↓,
1959- GamB,    Gambogic acid induces GSDME dependent pyroptotic signaling pathway via ROS/P53/Mitochondria/Caspase-3 in ovarian cancer cells
- in-vitro, Ovarian, NA - in-vivo, NA, NA
AntiCan↑, Pyro↑, tumCV?, CellMemb↓, cl‑Casp3↑, GSDME-N↑, ROS?, p‑P53↑, eff↓, MMP↓, Bcl-2↓, BAX↑, mtDam↑, Cyt‑c↑, TumCG↓, CD4+↑, CD8+↑,
1965- GamB,  doxoR,    Gambogic acid sensitizes ovarian cancer cells to doxorubicin through ROS-mediated apoptosis
- in-vitro, Ovarian, SKOV3
eff↑, AntiCan↑, ROS↑, ChemoSen↑,
4508- GLA,  aLinA,    α-Linolenic and γ-linolenic acids exercise differential antitumor effects on HT-29 human colorectal cancer cells
- in-vitro, Colon, HT29
Apoptosis↑, *Inflam↓, AntiCan↑, lipid-P↑, COX2↝, MKP1↝,
3771- H2,    Molecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer’s Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation—Fantasy or Reality?
- Review, AD, NA - Review, Stroke, NA
*cognitive↑, AntiCan↑, *Inflam↓, *antiOx↑, *ROS↓, *neuroP↑, *SOD↑, *GPx↑, *MDA↑, *BBB↑, *OS↑, *Ca+2↓, *APP↓, *p‑tau↓,
1641- HCAs,    Lung cancer induced by Benzo(A)Pyrene: ChemoProtective effect of sinapic acid in swiss albino mice
- in-vitro, Lung, A549 - in-vivo, Lung, NA
AntiCan↑, Igs↓, lipid-P↓, ROS↑, Casp3↑, Casp9↑, ChemoSideEff↓, Dose∅,
2082- HNK,    Revealing the role of honokiol in human glioma cells by RNA-seq analysis
- in-vitro, GBM, U87MG - in-vitro, GBM, U251
AntiCan↑, TumCP↑, TumAuto↑, Apoptosis↑, *BioAv↑, *neuroP↑, *NF-kB↑, MAPK↑, GPx4↑, Tf↑, BAX↑, Bcl-2↓, antiOx↑, Hif1a↓, Ferroptosis↑,
4523- HNK,  MAG,  BA,    Honokiol-Magnolol-Baicalin Possesses Synergistic Anticancer Potential and Enhances the Efficacy of Anti-PD-1 Immunotherapy in Colorectal Cancer by Triggering GSDME-Dependent Pyroptosis
- in-vitro, CRC, HCT116 - in-vitro, CRC, LoVo - in-vivo, CRC, HCT116
AntiCan↑, eff↑, TumCP↓, TumCCA↓, cycD1/CCND1↓, Pyro↑, Apoptosis↑, cl‑GSDME↑, Bcl-2↓, Cyt‑c↑, Casp9↑, TumCG↓,
4522- HNK,  MAG,    Honokiol Is More Potent than Magnolol in Reducing Head and Neck Cancer Cell Growth
- in-vitro, HNSCC, FaDu
AntiCan↑, tumCV↓, eff↑, survivin↓, RadioS↑,
2891- HNK,    Honokiol, an Active Compound of Magnolia Plant, Inhibits Growth, and Progression of Cancers of Different Organs
- Review, Var, NA
AntiCan↑, Inflam↓, antiOx↑, selectivity↑, *toxicity↓, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓, CDK4↓, TumMeta↓, NADPH↓, MMP2↓, MMP9↓, p‑mTOR↓, EGFR↓, EMT↓, SIRT1↑, SIRT3↑, EZH2↓, Snail↓, Vim↓, N-cadherin↓, E-cadherin↑, COX2↓, NF-kB↓, *ROS↓, Ca+2↑, ROS↑,
4634- HT,    Hydroxytyrosol in cancer research: recent and historical insights on discoveries and mechanisms of action
- Review, Var, NA
*antiOx↑, *Inflam↓, AntiCan↑, ChemoSen↑, chemoP↑,
4633- HT,    Unlocking the effective alliance of β-lapachone and hydroxytyrosol against triple-negative breast cancer cells
- in-vitro, BC, NA
AntiCan↑, CSCs↓, antiOx↑, NQO1↑, TumCCA↑, ER Stress↑, Apoptosis↑, UPR↑,
1787- LE,    Licorice and cancer
- Review, Var, NA
Inflam↓, AntiCan↓, DNAdam↓, LOX1↓, COX2↓, PKCδ↓, EGFR↓,
1789- LEC,    Lecithin Supplements and Breast Cancer Risk
- Analysis, NA, NA
AntiCan↑, Risk↓,
2906- LT,    Luteolin, a flavonoid with potentials for cancer prevention and therapy
- Review, Var, NA
*Inflam↓, AntiCan↑, antiOx⇅, Apoptosis↑, TumCP↓, TumMeta↓, angioG↓, PI3K↓, Akt↓, NF-kB↓, XIAP↓, P53↑, *ROS↓, *GSTA1↑, *GSR↑, *SOD↑, *Catalase↑, *other↓, ROS↑, Dose↝, chemoP↑, NF-kB↓, JNK↑, p27↑, P21↑, DR5↑, Casp↑, Fas↑, BAX↑, MAPK↓, CDK2↓, IGF-1↓, PDGF↓, EGFR↓, PKCδ↓, TOP1↓, TOP2↓, Bcl-xL↓, FASN↓, VEGF↓, VEGFR2↓, MMP9↓, Hif1a↓, FAK↓, MMP1↓, Twist↓, ERK↓, P450↓, CYP1A1↓, CYP1A2↓, TumCCA↑,
3268- Lyco,    Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders
- Review, AD, NA
*BioAv↓, *AntiCan↑, *ROCK1↓, *Ki-67↓, *ICAM-1↓, *cardioP↑, *antiOx↑, *NQO1↑, *HO-1↑, *TNF-α↓, *IL22↓, *NRF2↑, *NF-kB↓, *MDA↓, *Catalase↑, *SOD↑, *GSH↑, *cognitive↑, *tau↓, *hepatoP↑, *MMP2↑, *AST↓, *ALAT↓, *P450↑, *DNAdam↓, *ROS↓, *neuroP↑, *memory↑, *Ca+2↓, *Dose↝, *Dose↑, *Dose↝, *toxicity∅, PGE2↓, CDK2↓, CDK4↓, STAT3↓, NOX↓, NOX4↓, ROS↓, *SREBP1↓, *FASN↓, *ACC↓,
1708- Lyco,    The Anti-Cancer Activity of Lycopene: A Systematic Review of Human and Animal Studies
- Review, Var, NA
OS↑, ChemoSen↑, QoL↑, PSA∅, eff↑, AntiCan↑, AntiCan↑, angioG↓, VEGF↓, Hif1a↓, SOD↑, Catalase↑, GPx↑, GSH↑, GPx↑, GR↑, MDA↓, NRF2↑, HO-1↑, COX2↓, PGE2↓, NF-kB↓, IL4↑, IL10↑, IL6↓, TNF-α↓, PPARγ↑, TumCCA↑, FOXO3↓, Casp3↑, IGF-1↓, p27↑, STAT3↓, CDK2↓, CDK4↓, P21↑, PCNA↓, MMP7↓, MMP9↓,
4229- Lyco,    Implicating the role of lycopene in restoration of mitochondrial enzymes and BDNF levels in β-amyloid induced Alzheimer׳s disease
- in-vivo, AD, NA
*antiOx↑, *neuroP↑, *AntiCan↑, *memory↑, *ROS↓, *BDNF↑, *cognitive↑,
4780- Lyco,    Potential inhibitory effect of lycopene on prostate cancer
- Review, Pca, NA
TumCP↓, TumCCA↑, Apoptosis↑, *neuroP↑, *NF-kB↓, *JNK↓, *NRF2↑, *BDNF↑, *Ca+2↝, *antiOx↑, *AntiCan↑, *Inflam↓, *IL1↓, *IL6↓, *IL8↓, *TNF-α↓, NF-kB↓, DNAdam↓, PSA↓, P53↓, cycD1/CCND1↓, NRF2↓, Akt2↓, PPARγ↓,
4782- Lyco,    New Insights into Molecular Mechanism behind Anti-Cancer Activities of Lycopene
- Review, Var, NA
AntiCan↑, TumCP↓, TumCMig↓, TumCI↓, TumCA↓, ROS↓, MMP2↓, MMP7↓, MMP9↓, VEGF↓, E-cadherin↑, TIMP1↑, TIMP2↑, BioAv↝, *IL12↓, *TNF-α↓, *IL1↓, *IL1β↓, *IL6↓, COX2↓, iNOS↓, *radioP↑, NF-kB↓, survivin↓, Casp3↑, Bax:Bcl2↑,

Showing Research Papers: 101 to 150 of 268
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 268

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 4,   antiOx⇅, 1,   Catalase↑, 1,   CYP1A1↓, 1,   Ferroptosis↑, 1,   GPx↑, 2,   GPx4↑, 1,   GSH↓, 2,   GSH↑, 2,   GSTs↑, 1,   H2O2↓, 1,   HO-1↓, 1,   HO-1↑, 1,   lipid-P↓, 1,   lipid-P↑, 1,   MAD↓, 1,   MDA↓, 2,   MDA↑, 1,   NOX4↓, 1,   NQO1↑, 1,   NRF2↓, 1,   NRF2↑, 1,   mt-OXPHOS↑, 1,   PYCR1↓, 1,   ROS?, 1,   ROS↓, 2,   ROS↑, 16,   SIRT3↑, 1,   SOD↓, 1,   SOD↑, 1,   TrxR↓, 1,   TrxR1↓, 1,  

Metal & Cofactor Biology ⓘ

Tf↑, 1,  

Mitochondria & Bioenergetics ⓘ

FGFR1↓, 1,   Insulin↓, 2,   MMP↓, 9,   mtDam↑, 1,   OCR↓, 2,   Raf↓, 1,   XIAP↓, 3,  

Core Metabolism/Glycolysis ⓘ

AMPK↑, 3,   CAIX↓, 1,   cMyc↓, 1,   CRM↑, 1,   FASN↓, 1,   GlutMet↓, 1,   Glycolysis↓, 2,   LDH↓, 2,   NADPH↓, 1,   PDH↝, 1,   PDKs↓, 1,   PKM2↓, 1,   polyA↓, 1,   PPARγ↓, 1,   PPARγ↑, 1,   SIRT1↓, 2,   SIRT1↑, 2,   TS↓, 1,   Warburg↓, 1,  

Cell Death ⓘ

Akt↓, 7,   p‑Akt↓, 1,   APAF1↑, 1,   Apoptosis↑, 16,   BAD↓, 1,   Bak↑, 3,   BAX↑, 8,   Bax:Bcl2↑, 4,   Bcl-2↓, 8,   Bcl-xL↓, 2,   BID↓, 1,   Casp↑, 2,   Casp3↑, 9,   cl‑Casp3↑, 1,   Casp8↑, 1,   Casp9↑, 6,   cFLIP↓, 1,   Chk2↑, 1,   CK2↓, 1,   Cyt‑c↑, 6,   DR4↑, 1,   DR5↑, 2,   FADD↑, 1,   Fas↓, 1,   Fas↑, 1,   FasL↑, 1,   Ferroptosis↑, 1,   cl‑GSDME↑, 1,   GSDME-N↑, 1,   HGF/c-Met↓, 1,   hTERT/TERT↓, 1,   iNOS↓, 1,   JNK↑, 2,   MAPK↓, 4,   MAPK↑, 2,   MDM2↓, 1,   MKP1↝, 1,   Myc↓, 1,   p27↑, 3,   p38↑, 1,   Pyro↑, 2,   survivin↓, 5,   Telomerase↓, 2,  

Kinase & Signal Transduction ⓘ

FOXD3↑, 1,   HER2/EBBR2↓, 1,  

Transcription & Epigenetics ⓘ

EZH2↓, 1,   miR-21↓, 1,   miR-27a-3p↓, 1,   other↝, 2,   tumCV?, 1,   tumCV↓, 2,  

Protein Folding & ER Stress ⓘ

CHOP↑, 1,   ER Stress↑, 3,   ERStress↑, 1,   HSP90↓, 2,   UPR↑, 1,  

Autophagy & Lysosomes ⓘ

Beclin-1↑, 1,   LC3II↑, 2,   LC3s↑, 1,   p62↑, 1,   TumAuto↑, 4,  

DNA Damage & Repair ⓘ

CHK1↑, 1,   DNAdam↓, 2,   DNAdam↑, 2,   DNMTs↓, 1,   P53↓, 1,   P53↑, 5,   p‑P53↑, 1,   PARP↑, 1,   cl‑PARP↑, 2,   PCNA↓, 2,  

Cell Cycle & Senescence ⓘ

CDK2↓, 4,   CDK2↑, 1,   CDK4↓, 4,   cycD1/CCND1↓, 5,   cycE/CCNE↓, 1,   P21↑, 4,   TumCCA↓, 1,   TumCCA↑, 13,  

Proliferation, Differentiation & Cell State ⓘ

cFos↓, 1,   CIP2A↓, 1,   CSCs↓, 1,   EMT↓, 3,   ERK↓, 2,   ERK↑, 1,   FOXO3↓, 1,   GSK‐3β↓, 1,   HDAC↓, 1,   HDAC8↓, 1,   IGF-1↓, 4,   IGFR↓, 1,   miR-34a↑, 2,   mTOR↓, 3,   p‑mTOR↓, 1,   NOTCH↓, 2,   PI3K↓, 4,   PI3K↑, 1,   PTEN↑, 1,   STAT3↓, 4,   STAT3↑, 1,   STAT6↓, 1,   TOP1↓, 4,   TOP2↓, 2,   TumCG↓, 9,   Wnt↓, 2,  

Migration ⓘ

Akt2↓, 1,   Ca+2↑, 1,   E-cadherin↑, 3,   FAK↓, 2,   Ki-67↓, 2,   miR-200b↑, 1,   MMP1↓, 1,   MMP2↓, 6,   MMP7↓, 2,   MMP9↓, 8,   MMPs↓, 2,   N-cadherin↓, 1,   PDGF↓, 1,   PKCδ↓, 3,   Snail↓, 2,   TGF-β↑, 1,   TIMP1↑, 2,   TIMP2↑, 1,   TumCA↓, 1,   TumCI↓, 4,   TumCMig↓, 2,   TumCMig↑, 1,   TumCP↓, 12,   TumCP↑, 1,   TumMeta↓, 8,   Twist↓, 1,   uPA↓, 1,   Vim↓, 2,   β-catenin/ZEB1↓, 3,  

Angiogenesis & Vasculature ⓘ

angioG↓, 8,   EGFR↓, 5,   Hif1a↓, 6,   LOX1↓, 1,   VEGF↓, 6,   VEGFR2↓, 2,  

Barriers & Transport ⓘ

BBB↑, 1,   CellMemb↓, 1,   CellMemb↑, 1,   GLUT1↓, 1,   P-gp↓, 1,  

Immune & Inflammatory Signaling ⓘ

CD14↓, 1,   CD4+↑, 1,   COX2↓, 6,   COX2↝, 1,   CRP↓, 1,   IFN-γ↑, 1,   Igs↓, 1,   IL10↑, 1,   IL4↑, 1,   IL6↓, 1,   Inflam↓, 4,   Inflam↑, 1,   JAK2↓, 1,   NF-kB↓, 13,   NK cell↑, 1,   PD-1↓, 1,   PGE2↓, 2,   PSA↓, 1,   PSA∅, 1,   TNF-α↓, 1,  

Cellular Microenvironment ⓘ

NOX↓, 1,  

Hormonal & Nuclear Receptors ⓘ

CDK6↓, 2,   GR↑, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 4,   BioAv↑, 5,   BioAv↝, 2,   ChemoSen↓, 1,   ChemoSen↑, 13,   ChemoSen∅, 2,   CYP1A2↓, 1,   Dose?, 1,   Dose↝, 4,   Dose∅, 1,   eff↓, 6,   eff↑, 14,   P450↓, 1,   RadioS↑, 7,   selectivity↑, 6,  

Clinical Biomarkers ⓘ

BG↓, 1,   CRP↓, 1,   EGFR↓, 5,   EZH2↓, 1,   GutMicro↑, 1,   GutMicro↝, 1,   HER2/EBBR2↓, 1,   hTERT/TERT↓, 1,   IL6↓, 1,   Ki-67↓, 2,   LDH↓, 2,   Myc↓, 1,   PSA↓, 1,   PSA∅, 1,  

Functional Outcomes ⓘ

AntiCan↓, 1,   AntiCan↑, 41,   AntiTum↑, 1,   cardioP↑, 1,   chemoP↑, 3,   chemoPv↑, 4,   ChemoSideEff↓, 3,   OS↑, 1,   QoL↑, 1,   Risk↓, 2,   toxicity↓, 2,   toxicity⇅, 1,   TumVol↓, 1,   TumW↓, 1,  

Infection & Microbiome ⓘ

CD8+↑, 2,  
Total Targets: 271

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 15,   Catalase↑, 2,   GPx↑, 1,   GSH↑, 2,   GSR↑, 1,   GSTA1↑, 1,   HO-1↑, 1,   lipid-P↓, 1,   MDA↓, 1,   MDA↑, 1,   NQO1↑, 1,   NRF2↑, 3,   RNS↓, 1,   ROS↓, 12,   SOD↑, 3,   SOD1↑, 1,   SOD2↑, 1,  

Mitochondria & Bioenergetics ⓘ

Insulin↓, 1,  

Core Metabolism/Glycolysis ⓘ

ACC↓, 1,   ALAT↓, 1,   AMPK↑, 1,   FASN↓, 1,   GlucoseCon↑, 1,   SIRT1↑, 1,   SREBP1↓, 1,  

Cell Death ⓘ

iNOS↓, 1,   JNK↓, 1,  

Transcription & Epigenetics ⓘ

other↓, 2,   PhotoS↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,   P53↓, 1,  

Cell Cycle & Senescence ⓘ

E2Fs↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

IGF-1R↓, 1,   mTOR↓, 1,  

Migration ⓘ

AP-1↓, 1,   APP↓, 1,   Ca+2↓, 2,   Ca+2↝, 1,   Ki-67↓, 1,   MMP2↓, 1,   MMP2↑, 1,   ROCK1↓, 1,   TumCP↓, 1,  

Angiogenesis & Vasculature ⓘ

PDGFR-BB↓, 1,  

Barriers & Transport ⓘ

BBB↑, 2,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   ICAM-1↓, 1,   IL1↓, 2,   IL12↓, 1,   IL1β↓, 1,   IL22↓, 1,   IL6↓, 3,   IL8↓, 2,   Inflam↓, 13,   JAK↓, 1,   NF-kB↓, 3,   NF-kB↑, 1,   TNF-α↓, 5,  

Synaptic & Neurotransmission ⓘ

5HT↑, 1,   AChE↓, 1,   BDNF↑, 3,   tau↓, 1,   p‑tau↓, 1,  

Protein Aggregation ⓘ

Aβ↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 7,   BioAv↑, 4,   BioAv↝, 1,   Dose↑, 1,   Dose↝, 3,   Half-Life↝, 1,   P450↑, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 1,   AST↓, 1,   BP↓, 1,   IL6↓, 3,   Ki-67↓, 1,  

Functional Outcomes ⓘ

AntiAge↑, 2,   AntiCan↓, 1,   AntiCan↑, 8,   cardioP↑, 4,   chemoP↑, 1,   cognitive↑, 4,   hepatoP↓, 1,   hepatoP↑, 3,   memory↑, 3,   Mood↑, 1,   neuroP↑, 12,   Obesity↓, 1,   OS↑, 2,   QoL↑, 1,   radioP↑, 1,   toxicity↓, 3,   toxicity∅, 1,   Weight↓, 1,   Wound Healing↑, 1,  
Total Targets: 95

Scientific Paper Hit Count for: AntiCan, Anticancer Effect
18 Silver-NanoParticles
12 Lycopene
10 Thymoquinone
10 Selenium NanoParticles
8 Capsaicin
8 Magnolol
7 Allicin (mainly Garlic)
7 Phenethyl isothiocyanate
7 Quercetin
7 Sulforaphane (mainly Broccoli)
6 Astaxanthin
6 Baicalein
6 Curcumin
6 Gambogic Acid
6 Selenite (Sodium)
5 Artemisinin
5 Vitamin C (Ascorbic Acid)
4 Coenzyme Q10
4 chitosan
4 Apigenin (mainly Parsley)
4 Boron
4 Carvacrol
4 Chlorogenic acid
4 Honokiol
4 Naringin
4 Selenium
3 Melatonin
3 Aloe anthraquinones
3 beta-glucans
3 Biochanin A
3 Resveratrol
3 Spermidine
3 Ellagic acid
3 Propolis -bee glue
3 Pterostilbene
3 salinomycin
3 Silymarin (Milk Thistle) silibinin
3 Vitamin D3
3 Vitamin K2
2 3-bromopyruvate
2 Auranofin
2 doxorubicin
2 Alpha-Lipoic-Acid
2 Baicalin
2 Boswellia (frankincense)
2 Butyrate
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Thymol-Thymus vulgaris
2 Chlorophyllin
2 Camptothecin
2 Hydroxycinnamic-acid
2 Dichloroacetate
2 Ferulic acid
2 HydroxyTyrosol
2 Magnetic Fields
2 Bicarbonate(Sodium)
2 Piperine
2 Rosmarinic acid
2 Shikonin
2 Ursolic acid
2 Urolithin
2 VitK3,menadione
1 5-fluorouracil
1 Astragalus
1 Citric Acid
1 Ashwagandha(Withaferin A)
1 Ascorbyl Palmitate
1 Berberine
1 Betulinic acid
1 Bromelain
1 borneol
1 Bruteridin(bergamot juice)
1 Vitamin B3,Niacin
1 Caffeic acid
1 Caffeine
1 urea
1 Celastrol
1 Chrysin
1 irinotecan
1 Calorie Restriction Mimetics
1 Aspirin -acetylsalicylic acid
1 diet FMD Fasting Mimicking Diet
1 diet Methionine-Restricted Diet
1 diet Plant based
1 EGCG (Epigallocatechin Gallate)
1 Electrical Pulses
1 Gallic acid
1 γ-linolenic acid (Borage Oil)
1 alpha Linolenic acid
1 Hydrogen Gas
1 Licorice
1 Lecithin
1 Luteolin
1 Methylene blue
1 Photodynamic Therapy
1 mebendazole
1 Metformin
1 Magnetic Field Rotating
1 Methylglyoxal
1 Oleocanthal
1 Piperlongumine
1 Psoralidin
1 Parthenolide
1 Salvia officinalis
1 Radiotherapy/Radiation
1 Date Fruit Extract
1 Calcium
1 Aflavin-3,3′-digallate
1 Magnesium
1 Zerumbone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:813  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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