tumCV Cancer Research Results

tumCV, Cell Viability: Click to Expand ⟱
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Cell Viability
Scientific Papers found: Click to Expand⟱
5836- CAP,    In vitro and in vivo induction of apoptosis by capsaicin in pancreatic cancer cells is mediated through ROS generation and mitochondrial death pathway
- vitro+vivo, PC, AsPC-1 - in-vitro, PC, Bxpc-3
tumCV↓, Apoptosis↑, ROS↑, MMP↓, eff↓, BAX↑, Bcl-2↓, survivin↓, Cyt‑c↑, AIF↑, selectivity↑, JNK↑, TumCG↓,
5835- CAP,    Capsaicin and dihydrocapsaicin induce apoptosis in human glioma cells via ROS and Ca2+-mediated mitochondrial pathway
- in-vitro, GBM, U251
tumCV↓, Apoptosis↑, selectivity↑, ROS↑, Ca+2↑, MMP↓, Cyt‑c↑, Casp↑, eff↑, MPT↑, ETC↓, Casp3↑, Casp9↑,
5832- CAP,    Capsaicin induces cell cycle arrest and apoptosis in human KB cancer cells
- in-vitro, Oral, KB
TumCP↓, tumCV↓, TumCCA↑, Apoptosis↑, MMP↓, Casp9↑, Casp3↑, PARP↑, Inflam↓, Pain↓,
5826- CAP,    Capsaicin induces mitochondrial dysfunction and apoptosis in anaplastic thyroid carcinoma cells via TRPV1-mediated mitochondrial calcium overload
- in-vitro, Thyroid, NA
TRPV1↑, tumCV↓, Ca+2↑, mtDam↑, ROS↑, MMP↓, MPT↑, Cyt‑c↑, Casp↑, Apoptosis↑,
5203- CAP,    Capsaicin Promotes Apoptosis and Inhibits Cell Migration via the Tumor Necrosis Factor-Alpha (TNFα) and Nuclear Factor Kappa B (NFκB) Signaling Pathway in Oral Cancer Cells
- in-vitro, OS, KB
tumCV↓, TNF-α↓, NF-kB↓, selectivity↑, Apoptosis↑, TumCMig↓,
5198- CAP,    Capsaicin induces apoptosis by generating reactive oxygen species and disrupting mitochondrial transmembrane potential in human colon cancer cell lines
- in-vitro, CRC, LoVo - in-vitro, CRC, Colo320
tumCV↓, DNAdam↑, Apoptosis↑, ROS↑, MMP↑, Casp3↑, chemoPv↑,
5769- CAPE,    Caffeic Acid Phenethyl Ester Inhibits the Proliferation of HEp2 Cells by Regulating Stat3/Plk1 Pathway and Inducing S Phase Arrest
- in-vitro, Laryn, HEp2
tumCV↓, STAT3↓, TumCCA↑,
5767- CAPE,    Caffeic Acid Phenethyl Ester Is a Potential Therapeutic Agent for Oral Cancer
- Review, Oral, NA
TumCP↓, tumCV↓, TumMeta↓, Akt↓, NF-kB↓, MMPs↓, EGFR↓, COX2/PTGS2↓, TumCCA?,
5754- CAPE,  Rad,    The radiosensitizing effect of Caffeic Acid Phenethyl Ester in breast cancer is dependent on p53 status
- in-vivo, BC, MDA-MB-231
tumCV↓, eff⇅, RadioS↑, OS↑,
5885- CAR,    Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion
- in-vitro, GBM, U87MG - in-vitro, Nor, HEK293
TRPM7↓, tumCV↓, TumCMig↓, TumCI↓, MMP2↓, toxicity↓, *Inflam↓, AntiDiabetic↑, cardioP↑, neuroP↑, selectivity↑, Apoptosis↑, p‑Cofilin↑, F-actin↓, PI3K↓, Akt↓, MEK↓, MAPK↓,
5884- CAR,    Carvacrol affects breast cancer cells through TRPM7 mediated cell cycle regulation
- in-vitro, BC, BT474 - in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-453
TRPM7↓, tumCV↓, TumCCA↑,
5882- CAR,    Carvacrol Promotes Cell Cycle Arrest and Apoptosis through PI3K/AKT Signaling Pathway in MCF-7 Breast Cancer Cells
- in-vitro, BC, MCF7
tumCV↓, TumCCA↑, pRB↓, cycD1/CCND1↓, CDK4↓, CDK6↓, PI3K↓, p‑Akt↓, Apoptosis↑, Bcl-2↓, BAX↑,
5905- CAR,  HCQ,    Synergistic inhibition of metastatic melanoma by carvacrol and chloroquine: an in vitro and in silico investigation of apoptosis and molecular targets
- in-vitro, Melanoma, NA
eff↑, tumCV↑, IGF-1R↓, SIRT2↓, HSP90↓, TumCP↓, Akt↓,
5906- CAR,    Screening and Validation of a Carvacrol-Targeting Viability-Regulating Protein, SLC6A3, in Liver Hepatocellular Carcinoma
- in-vitro, HCC, NA
tumCV↓, SLC6A3?,
5912- CAR,    Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation migration and invasion
- in-vitro, GBM, U87MG - in-vitro, Nor, HEK293
TRPM7↓, tumCV↓, TumCMig↓, TumCI↓, MMP2↓, p‑Cofilin↑, RAS↓, MEK↓, MAPK↓, PI3K↓, Akt↓,
1104- CAR,    Carvacrol Ameliorates Transforming Growth Factor-β1-Induced Extracellular Matrix Deposition and Reduces Epithelial-Mesenchymal Transition by Regulating The Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway In Hk-2 Cells
- in-vitro, Kidney, HK-2
tumCV↓, COL4↓, COL1↓, Fibronectin↓, E-cadherin↑, Snail↑, Vim↑, α-SMA↑, PI3K↓, Akt↓,
939- Catechins,  5-FU,    Targeting Lactate Dehydrogenase A with Catechin Resensitizes SNU620/5FU Gastric Cancer Cells to 5-Fluorouracil
- vitro+vivo, GC, SNU620
lactateProd↓, ROS↑, tumCV↓, LDHA↓, mt-ROS↑, proApCas↑,
5817- CBD,    COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells
- vitro+vivo, Lung, A549
AntiTum⇅, tumCV↓, Apoptosis↑, eff↓, COX2/PTGS2↑, PPARγ↑,
6652- Cen,    AA-PMe, a novel asiatic acid derivative, induces apoptosis and suppresses proliferation, migration, and invasion of gastric cancer cells
- in-vitro, GC, SGC-7901 - in-vitro, GC, HGC27
TumCP↓, selectivity↑, TumCCA↑, cycD1/CCND1↓, CDK4↓, Apoptosis↑, Bcl-2↓, BAX↑, cMyc↓, Casp3↑, TumCMig↓, TumCI↓, MMP2↓, MMP9↓, tumCV↓,
6643- Cen,    Asiaticoside inhibits epithelial-mesenchymal transition and stem cell-like properties of pancreatic cancer PANC-1 cells by blocking the activation of p65 and p38MAPK
- vitro+vivo, PC, PANC1
tumCV↓, Ki-67↓, PCNA↓, N-cadherin↓, Vim↓, SOX2↓, OCT4↓, p65↓, MAPK↓, CD44↓, CD133↓, E-cadherin↑, TumVol↓, TumCP↓, EMT↓, CSCsMark↓,
6017- CGA,    Therapeutic Potential of Chlorogenic Acid in Chemoresistance and Chemoprotection in Cancer Treatment
- Review, Var, NA
AntiCan↑, *chemoP↑, TNF-α↓, COX2/PTGS2↓, IL6↓, eff↑, PD-L1↓, *cognitive↓, *Aβ↓, *TAC↑, *SOD↑, *eff↑, *eff↑, ChemoSen↑, tumCV↓, Apoptosis↑, ERK↓, chemoP↑, *GPx↑, *GSTs↑, *GSH↑, *SOD↑, *Catalase↑, *ROS↓, *lipid-P↓, *MDA↓, *Casp3↓, *HO-1↓, cardioP↑, radioP↑,
6030- CGA,    Chlorogenic acid induces apoptosis, inhibits metastasis and improves antitumor immunity in breast cancer via the NF‑κB signaling pathway
- vitro+vivo, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-453 - in-vitro, Nor, MCF10
NF-kB↓, AntiTum↑, tumCV↓, TumCP↓, Apoptosis↑, TumCMig↓, TumCI↓, EMT↓, TumCG↓, OS↑, TumMeta↓, CD4+↑, CD8+↑, Imm↑,
6630- CGA,    In Vitro and In Silico Study on the Impact of Chlorogenic Acid in Colorectal Cancer Cells: Proliferation, Apoptosis, and Interaction with β-Catenin and LRP6
- in-vitro, CRC, HT29 - in-vitro, CRC, SW480
tumCV↓, DNAdam↑, mt-ROS↑, MMP↓, Casp3↑, eff↝,
7177- CHA,    Chaetocin inhibits the progression of neuroblastoma by targeting JAK2/STAT3 signaling pathway in SH-SY5Y cells
- NA, neuroblastoma, SH-SY5Y
AntiCan↑, Inflam↓, tumCV↓, Apoptosis↑, TumCMig↓, TumCI↓, JAK2↓, STAT3↓,
7178- CHA,    SUV39H1 Regulates Gastric Cancer Progression via the H3K9me3/ALDOB Axis
- in-vitro, GC, NA
tumCV↓, TumCG↓, SUV39H↓,
7181- CHA,    Chaetocin induces cell cycle arrest and apoptosis by regulating the ROS-mediated ASK-1/JNK signaling pathways
TumCCA↑, ROS↑, ASK1↑, JNK↑, HMTs↓, Trx↓, tumCV↓, TumCI↓,
7166- CHA,    Anti-leukemia activity of chaetocin via death receptor-dependent apoptosis and dual modulation of the histone methyl-transferase SUV39H1
- vitro+vivo, AML, U937
SUV39H↓, Apoptosis↑, ROS↑, TumCCA↑, tumCV↓, Casp3↑, Casp9↑, Fas↑, FasL↑, DR4↑, P21↑, eff↓, eff↑,
7164- CHA,    Chaetocin induces apoptosis in human melanoma cells through the generation of reactive oxygen species and the intrinsic mitochondrial pathway, and exerts its anti-tumor activity in vivo
- vitro+vivo, Melanoma, A375
TumCP↓, Apoptosis↑, ROS↑, eff↓, MMP↓, Cyt‑c↑, BAX↑, cl‑Casp3↑, cl‑Casp9↑, Bcl-2↓, TumCG↓, PCNA↓, tumCV↓, NRF2↑, SOD2↑, Catalase↑, NRF2↓, SOD2↓, Catalase↓, TrxR↓,
4493- Chit,  Selenate,  Se,    A novel synthetic chitosan selenate (CS) induces apoptosis in A549 lung cancer cells via the Fas/FasL pathway
- in-vitro, Lung, A549
tumCV↓, Apoptosis↑, TumCCA↑, Fas↑, FasL↑, FADD↑, Casp↑,
6130- CHr,    Anticancer Properties of Chrysin on Colon Cancer Cells, In vitro and In vivo with Modulation of Caspase-3, -9, Bax and Sall4
- vitro+vivo, Colon, CT26
tumCV↓, Apoptosis↑, TumVol↓, BAX↑, SALL4↓, Casp3↑, Casp9↑, ChemoSen↑, GSH↓,
6128- CHr,    Chrysin: A Comprehensive Review of Its Pharmacological Properties and Therapeutic Potential
- Review, Nor, NA - Review, Var, NA - Review, AD, NA
*antiOx↑, *Inflam↓, AntiCan↑, *neuroP↑, *ROS↓, *BioAv↓, *BioAv↑, *cardioP↑, *COX2/PTGS2↓, *TNF-α↓, *IL1β↓, *NF-kB↓, *lipid-P↓, *Apoptosis↓, *NRF2↑, *HO-1↑, *MDA↓, *GSH↑, *SOD↑, *GPx↑, *GSR↑, *Catalase↑, *5HT↑, *Casp3↓, *Casp9↓, TumCCA↑, MAPK↓, PI3K↓, Akt↓, TumCP↓, TET1↑, TLR4↓, HER2/EBBR2↓, HK2↓, Glycolysis↓, glucose↓, lactateProd↓, ROS↑, mTOR↓, TumAuto↑, tumCV↓, ER Stress↑, UPR↑, PERK↑, ATF4↑, eIF2α↑, BioAv↑,
6126- CHr,    Chrysin induces cell apoptosis in human uveal melanoma cells via intrinsic apoptosis
- in-vitro, Melanoma, NA
tumCV↓, selectivity↑, MPT↑, Cyt‑c↑, Casp3↑, Casp9↑, Apoptosis↑, mtDam↑, chemoPv↑,
2797- CHr,    A flavonoid chrysin suppresses hypoxic survival and metastatic growth of mouse breast cancer cells
- in-vivo, BC, NA - in-vitro, BC, 4T1
tumCV↓, p‑STAT3↓, VEGF↓, Weight∅, angioG↓,
2787- CHr,    Network pharmacology unveils the intricate molecular landscape of Chrysin in breast cancer therapeutics
- Analysis, Var, MCF7
TumCP↓, angioG↓, TumCI↓, TumMeta↓, TP53↑, Akt↓, Casp3↑, tumCV↓, TNF-α↓, BioAv↑, BioAv↑, AKT1↓,
1145- CHr,    Chrysin inhibits propagation of HeLa cells by attenuating cell survival and inducing apoptotic pathways
- in-vitro, Cerv, HeLa
tumCV↓, BAX↑, BID↑, BOK↑, APAF1↑, TNF-α↑, FasL↑, Fas↑, FADD↑, Casp3↑, Casp7↑, Casp8↑, Casp9↑, Mcl-1↓, NAIP↓, Bcl-2↓, CDK4↓, CycB/CCNB1↓, cycD1/CCND1↓, cycE1↓, TRAIL↑, p‑Akt↓, Akt↓, mTOR↓, PDK1 / PDPK1↓, BAD↓, GSK‐3β↑, AMPK↑, p27/CDKN1B↑, P53↑,
6628- Cic,    The Prevention and Treatment of Colorectal Cancer by Traditional Plants
- Review, CRC, NA
tumCV↓, Telomerase↓, Casp9↑, cl‑PARP↑, TumCP↓, β-catenin/ZEB1↓,
6633- Cic,    Chicoric acid (Synonyms: Cichoric acid; Dicaffeoyltartaric acid)
- Review, NA, NA
ROS↑, tumCV↓,
1593- Citrate,    Citrate Induces Apoptotic Cell Death: A Promising Way to Treat Gastric Carcinoma?
- in-vitro, GC, BGC-823 - in-vitro, GC, SGC-7901
PFK↓, Glycolysis↓, tumCV↓, cl‑Casp3↑, cl‑PARP↑, Apoptosis↑, ATP↓, ChemoSen↑, Mcl-1↓, glucoNG↑, FBPase↑, OXPHOS↓, TCA↓, β-oxidation↓, HK2↓, PDH↓, ROS↑,
1592- Citrate,    Inhibition of Mcl-1 expression by citrate enhances the effect of Bcl-xL inhibitors on human ovarian carcinoma cells
- in-vitro, Ovarian, SKOV3 - in-vitro, Ovarian, IGROV1
eff↑, tumCV↓, Mcl-1↓, eff↑,
1584- Citrate,    Anticancer effects of high-dose extracellular citrate treatment in pancreatic cancer cells under different glucose concentrations
- in-vitro, PC, MIA PaCa-2 - in-vitro, PC, PANC1
tumCV↓, i-Ca+2↓, TumCMig↓, CD133↓, pH↑, eff↑, Ki-67↓, eff↑,
4764- CoQ10,  VitE,    Auxiliary effect of trolox on coenzyme Q10 restricts angiogenesis and proliferation of retinoblastoma cells via the ERK/Akt pathway
- in-vitro, RPE, Y79 - in-vitro, Nor, ARPE-19 - in-vivo, NA, NA
tumCV↓, Apoptosis↑, ROS↑, MMP↓, TumCCA↑, VEGF↓, ERK↓, Akt↓, ChemoSen↑, chemoP↑, toxicity↓, angioG↓,
4776- CoQ10,    Antitumor properties of Coenzyme Q0 against human ovarian carcinoma cells via induction of ROS-mediated apoptosis and cytoprotective autophagy
- vitro+vivo, Ovarian, SKOV3
ROS↑, eff↓, AntiCan↑, Apoptosis↑, tumCV↓, TumCG↓, TumCCA↑, LC3s↑, ERStress↑, Beclin-1/ATG6↑, Bax:Bcl2↑, HER2/EBBR2↓, Akt↓, mTOR↓,
6312- Cro,    Crocin from Crocus Sativus Possesses Significant Anti-Proliferation Effects on Human Colorectal Cancer Cells
- in-vitro, CRC, HCT116 - in-vitro, CRC, SW48 - in-vitro, CRC, HT29
tumCV↓, TumCG↓, selectivity↑,
6309- Cro,    Crocin exerts anti-tumor effect in colon cancer cells via repressing the JaK pathway
- in-vitro, CRC, HCT116
tumCV↓, TumCP↓, Ki-67↓, Apoptosis↓, Inflam↓, ROS↑, MMP↓, JAK2↓, STAT3↓, ERK↓, MIP2↓, IL6↓, MCP1/CCL2↓, IL8↓, IL1β↓, TNF-α↓, SOD↓, Catalase↓, GSH↓, ROS↑, mtDam↑,
6304- Cro,    Crocin attenuates NF-κB-mediated inflammation and proliferation in breast cancer cells by down-regulating PRKCQ
- in-vitro, BC, NA
NF-kB↓, tumCV↓, TumCP↓, TNF-α↓, IL1β↓, Inflam↓, PRKCQ/PKCθ↓,
6334- Cro,  Eug,  Rad,    Crocin and eugenol enhance radiosensitivity in oral squamous cell carcinoma cells via apoptotic pathways and cell cycle regulation. Type of study: in vitro
- in-vitro, OS, NA
tumCV↓, RadioS↑, TumCCA↑, BAX↑, Casp3↑, Bcl-2↓, cycA1/CCNA1↓, CycB/CCNB1↓,
6301- Cro,    Crocin Inhibits Angiogenesis and Metastasis in Colon Cancer via TNF-α/NF-kB/VEGF Pathways
- vitro+vivo, Colon, HT29 - in-vitro, Colon, Caco-2
tumCV↓, selectivity↑, TumCMig↓, TumCI↓, angioG↓, TNF-α↓, NF-kB↓, VEGF↓, TumMeta↓,
6525- CRV,    D-carvone induced ROS mediated apoptotic cell death in human leukemic cell lines (Molt-4)
- in-vitro, AML, NA
tumCV↓, ROS↑, antiOx↓, MMP↓, Apoptosis↑, Casp8↑, Casp9↑, Casp3↑, *neuroP↑, AntiCan↑, *AntiArt↑, TBARS↑, SOD↓, GSH↓, Catalase↓,
6533- CRV,    Potential anticancer activity of carvone in N2a neuroblastoma cell line
- in-vitro, neuroblastoma, N9
*antiOx↑, tumCV↓,
6532- CRV,  doxoR,    R-(-)-carvone Attenuated Doxorubicin Induced Cardiotoxicity In Vivo and Potentiated Its Anticancer Toxicity In Vitro
- in-vivo, BC, MCF7 - in-vivo, Nor, H9c2
tumCV↓, ChemoSen↑, cardioP↑, *Catalase↑,

Showing Research Papers: 101 to 150 of 520
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 520

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

PRKCQ/PKCθ↓, 1,   SALL4↓, 1,   SUV39H↓, 2,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   Catalase↓, 3,   Catalase↑, 1,   GSH↓, 3,   NRF2↓, 1,   NRF2↑, 1,   OXPHOS↓, 1,   ROS↑, 16,   mt-ROS↑, 2,   SOD↓, 2,   SOD2↓, 1,   SOD2↑, 1,   TBARS↑, 1,   Trx↓, 1,   TrxR↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 1,   ATP↓, 1,   BOK↑, 1,   ETC↓, 1,   MEK↓, 2,   MMP↓, 9,   MMP↑, 1,   MPT↑, 3,   mtDam↑, 3,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AKT1↓, 1,   AMPK↑, 1,   cMyc↓, 1,   FBPase↑, 1,   glucoNG↑, 1,   glucose↓, 1,   Glycolysis↓, 2,   HK2↓, 2,   lactateProd↓, 2,   LDHA↓, 1,   PDH↓, 1,   PDK1 / PDPK1↓, 1,   PFK↓, 1,   PPARγ↑, 1,   SIRT2↓, 1,   TCA↓, 1,   β-oxidation↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 10,   p‑Akt↓, 2,   APAF1↑, 1,   Apoptosis↓, 1,   Apoptosis↑, 22,   ASK1↑, 1,   BAD↓, 1,   BAX↑, 7,   Bax:Bcl2↑, 1,   Bcl-2↓, 6,   BID↑, 1,   Casp↑, 3,   Casp3↑, 12,   cl‑Casp3↑, 2,   Casp7↑, 1,   Casp8↑, 2,   Casp9↑, 8,   cl‑Casp9↑, 1,   Cyt‑c↑, 5,   DR4↑, 1,   FADD↑, 2,   Fas↑, 3,   FasL↑, 3,   JNK↑, 2,   MAPK↓, 4,   Mcl-1↓, 3,   NAIP↓, 1,   p27/CDKN1B↑, 1,   proApCas↑, 1,   survivin↓, 1,   Telomerase↓, 1,   TRAIL↑, 1,   TRPV1↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HER2/EBBR2↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

pRB↓, 1,   tumCV↓, 49,   tumCV↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

eIF2α↑, 1,   ER Stress↑, 1,   ERStress↑, 1,   HSP90↓, 1,   PERK↑, 1,   UPR↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↑, 1,   LC3s↑, 1,   TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 2,   P53↑, 1,   PARP↑, 1,   cl‑PARP↑, 2,   PCNA↓, 2,   TP53↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK4↓, 3,   cycA1/CCNA1↓, 1,   CycB/CCNB1↓, 2,   cycD1/CCND1↓, 3,   cycE1↓, 1,   P21↑, 1,   TumCCA?, 1,   TumCCA↑, 12,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD133↓, 2,   CD44↓, 1,   CSCsMark↓, 1,   EMT↓, 2,   ERK↓, 3,   GSK‐3β↑, 1,   HMTs↓, 1,   IGF-1R↓, 1,   mTOR↓, 3,   OCT4↓, 1,   PI3K↓, 5,   RAS↓, 1,   SOX2↓, 1,   STAT3↓, 3,   p‑STAT3↓, 1,   TRPM7↓, 3,   TumCG↓, 6,  

Migration(tgid=13) ⓘ

Ca+2↑, 2,   i-Ca+2↓, 1,   p‑Cofilin↑, 2,   COL1↓, 1,   COL4↓, 1,   E-cadherin↑, 2,   F-actin↓, 1,   Fibronectin↓, 1,   Ki-67↓, 3,   MMP2↓, 3,   MMP9↓, 1,   MMPs↓, 1,   N-cadherin↓, 1,   Snail↑, 1,   TET1↑, 1,   TumCI↓, 8,   TumCMig↓, 8,   TumCP↓, 12,   TumMeta↓, 4,   Vim↓, 1,   Vim↑, 1,   α-SMA↑, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 4,   ATF4↑, 1,   EGFR↓, 1,   VEGF↓, 3,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   COX2/PTGS2↓, 2,   COX2/PTGS2↑, 1,   IL1β↓, 2,   IL6↓, 2,   IL8↓, 1,   Imm↑, 1,   Inflam↓, 4,   JAK2↓, 2,   MCP1/CCL2↓, 1,   MIP2↓, 1,   NF-kB↓, 5,   p65↓, 1,   PD-L1↓, 1,   TLR4↓, 1,   TNF-α↓, 6,   TNF-α↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

pH↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CDK6↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 3,   ChemoSen↑, 5,   eff↓, 5,   eff↑, 8,   eff⇅, 1,   eff↝, 1,   RadioS↑, 2,   selectivity↑, 8,  

Clinical Biomarkers(tgid=22) ⓘ

EGFR↓, 1,   HER2/EBBR2↓, 2,   IL6↓, 2,   Ki-67↓, 3,   PD-L1↓, 1,   SLC6A3?, 1,   TP53↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 5,   AntiDiabetic↑, 1,   AntiTum↑, 1,   AntiTum⇅, 1,   cardioP↑, 3,   chemoP↑, 2,   chemoPv↑, 2,   neuroP↑, 1,   OS↑, 2,   Pain↓, 1,   radioP↑, 1,   toxicity↓, 2,   TumVol↓, 2,   Weight∅, 1,  

Infection & Microbiome(tgid=24) ⓘ

CD8+↑, 1,  
Total Targets: 197

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiArt↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 2,   Catalase↑, 3,   GPx↑, 2,   GSH↑, 2,   GSR↑, 1,   GSTs↑, 1,   HO-1↓, 1,   HO-1↑, 1,   lipid-P↓, 2,   MDA↓, 2,   NRF2↑, 1,   ROS↓, 2,   SOD↑, 3,   TAC↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,   Casp3↓, 2,   Casp9↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   IL1β↓, 1,   Inflam↓, 2,   NF-kB↓, 1,   TNF-α↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 1,   eff↑, 2,  

Functional Outcomes(tgid=23) ⓘ

cardioP↑, 1,   chemoP↑, 1,   cognitive↓, 1,   neuroP↑, 2,  
Total Targets: 32

Scientific Paper Hit Count for: tumCV, Cell Viability
22 Silver-NanoParticles
17 Quercetin
14 Thymoquinone
12 Curcumin
12 Sulforaphane (mainly Broccoli)
11 Cisplatin
11 Honokiol
10 Licochalcone A
9 Dandelion Root
9 Fisetin
9 Kaempferol
9 Phenethyl isothiocyanate
8 Betulinic acid
8 Magnetic Fields
7 SonoDynamic Therapy UltraSound
7 Berberine
7 Capsaicin
7 Carvacrol
7 Eugenol
7 Cynaropicrin
7 Gallic acid
7 Shikonin
6 Cynara scolymus/Globe Artichoke/Artichoke Extract
6 Allicin (mainly Garlic)
6 Radiotherapy/Radiation
6 Chrysin
6 Resveratrol
6 Emodin
6 Hyperoside
6 Ivermectin
5 chaetocin
5 Crocetin
5 doxorubicin
5 Formononetin
5 Ginkgetin
5 isoquercitrin
5 Rosmarinic acid
4 Apigenin (mainly Parsley)
4 Metformin
4 Artemisinin
4 Baicalein
4 Berbamine
4 Biochanin A
4 Gemcitabine (Gemzar)
4 Caffeic Acid Phenethyl Ester (CAPE)
4 5-fluorouracil
4 Chlorogenic acid
4 Carvone
4 Eurycomanone
4 Shilajit/Fulvic Acid
4 Graviola
4 iodine
4 Juglone
4 Propolis -bee glue
4 α-Santalol/Sandalwood oil
4 Silymarin (Milk Thistle) silibinin
4 Vitamin C (Ascorbic Acid)
4 Vitexin
3 Ashwagandha(Withaferin A)
3 Astaxanthin
3 Beta-Caryophyllene
3 Carnosic acid
3 chitosan
3 Selenium
3 Citric Acid
3 CUSP9
3 Dichloroacetate
3 Echinacea
3 eicosapentaenoic acid
3 Evodiamine
3 Fucoidan
3 Gambogic Acid
3 Hibiscus sabdariffa
3 Magnolol
3 Hyperthermia
3 HydroxyTyrosol
3 Lycopene
3 Methylene blue
3 Magnetic Field Rotating
3 Nimbolide
3 Piperlongumine
3 Plumbagin
3 Parthenolide
3 Selenite (Sodium)
3 Terpinen-4-ol / Tea Tree Oil
3 Urolithin
2 3-bromopyruvate
2 Alpha-Lipoic-Acid
2 Anethole/trans-Anethole
2 Aloe anthraquinones
2 Bacopa monnieri
2 Boswellia (frankincense)
2 brusatol
2 Caffeic acid
2 Centella asiatica / Gotu kola → asiaticoside
2 Cichoric acid / Chicoric acid
2 Coenzyme Q10
2 Polyphenols
2 Copper and Cu NanoParticles
2 Hydroxycinnamic-acid
2 D-limonene
2 tamoxifen
2 EGCG (Epigallocatechin Gallate)
2 Garcinol
2 Ginkgolic acids
2 Ginkgo biloba
2 Geraniol
2 Helleborus niger extracts – Christmas Rose
2 Rutin
2 isoorientin
2 Lasiodin
2 Luteolin
2 Iron
2 Gold NanoParticles
2 Methylsulfonylmethane
2 Naringin
2 Piperine
2 salinomycin
2 polyethylene glycol
2 Selenium NanoParticles
2 Chemotherapy
2 Photodynamic Therapy
2 Aflavin-3,3′-digallate
2 Ursolic acid
2 VitK3,menadione
2 Zerumbone
1 1,8-Cineole
1 Resiquimod
1 DTS(dibenzyl trisulphide) from Anamu
1 Andrographis
1 Ascorbyl Palmitate
1 Trastuzumab
1 Melatonin
1 Atorvastatin
1 Bevacizumab (brand Avastin)
1 borneol
1 Boron
1 α-Bisabolol / Chamomile oil
1 Bullatacin
1 hydroxychloroquine
1 Catechins
1 Cannabidiol
1 Selenate
1 Vitamin E
1 Docosahexaenoic Acid
1 Disulfiram
1 Ellagic acid
1 Cannabichromene
1 Ginkgo biloba-EGb 761
1 Electrical Pulses
1 Estrogen
1 Ferulic acid
1 Fenbendazole
1 Fennel Oil/Foeniculum vulgare
1 olaparib/LYNPARZA
1 Genistein (soy isoflavone)
1 Ginseng
1 γ-linolenic acid (Borage Oil)
1 Hydrogen Gas
1 HydroxyCitric Acid
1 Paclitaxel/Taxol
1 Indole-3-carbinol
1 Isobavachalcone
1 Inositol
1 metronomic chemo
1 Isoliquiritigenin
1 itraconazole
1 Lactobacillus
1 lambertianic acid
1 Lapachol
1 Licorice
1 Lemongrass Extract/Citral
1 Folic Acid, Vit B9
1 Methyl salicylate / Sweet Birch oil
1 Aspirin
1 immunotherapy
1 Mushroom Chaga
1 Bicarbonate(Sodium)
1 Niclosamide (Niclocide)
1 Oleuropein
1 Phenylbutyrate
1 Propyl gallate
1 Pterostilbene
1 Perilla
1 Scoulerine
1 acetazolamide
1 Triphala
1 triptolide
1 Turmerones
1 Vitamin D3
1 Vitamin K2
1 Whole Body Vibration
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:897  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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