Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
7946- BuckWS,    Extract of buckwheat sprouts scavenges oxidation and inhibits pro-inflammatory mediators in lipopolysaccharide-stimulated macrophages (RAW264.7)
- Study, Nor, NA
*ROS↓, *IronCh↑, *IL6↓, *TNF-α↓, *iNOS↓, *COX2/PTGS2↓,
7948- BuckWS,    Blood pressure-lowering peptides from neo-fermented buckwheat sprouts: a new approach to estimating ACE-inhibitory activity
- in-vivo, Nor, NA
*ACE/ACE1↓, *BP↓,
7949- BuckWS,    Producing High-Quality Buckwheat Sprouts: The Combined Effects of Melatonin and UV-B Treatment
- Study, Nor, NA
*eff↑, *SOD↑, *GPx↑, *Catalase↑, *other↑,
7950- BuckWS,    Optimization of Ultraviolet-B Treatment for Enrichment of Total Flavonoids in Buckwheat Sprouts Using Response Surface Methodology and Study on Its Metabolic Mechanism
- Study, Nor, NA
*eff↑, *eff↝, *other↑,
7952- BuckWS,  RT,  QC,    Pasta containing tartary buckwheat sprouts prevents DNA damage in spontaneously hypertensive rats
*DNAdam↓, *DNArepair↑, *Dose?,
7953- BuckWS,  RT,    Review of the protective effects of rutin on the metabolic function as an important dietary flavonoid
- Review, Nor, NA
*GastroP↑, *hepatoP↑, *AntiDiabetic↑, *Inflam↓, *BioAv↓, *LDL↓, *Fenton↓, *AGEs↓, *GSH↑, *Dose↝,
7955- BuckWS,    Buckwheat (Fagopyrum esculentum M.) Sprout Treated with Methyl Jasmonate (MeJA) Improved Anti-Adipogenic Activity Associated with the Oxidative Stress System in 3T3-L1 Adipocytes
- in-vitro, Nor, 3T3
*eff↑, *ROS↓, *lipid-P↓,
7956- BuckWS,    Aqua-culture improved buckwheat sprouts with more abundant precious nutrients and hypolipidemic activity
- in-vitro, Nor, NA
*Stroke↓, *cardioP↑, *eff↑, *Dose↑,
7957- BuckWS,    Improving the antioxidant activity of buckwheat (Fagopyrum tataricm Gaertn) sprout with trace element water
- Study, Nor, NA
*Dose↑, *eff↑, *eff↝, *ROS↓, *IronCh↑, *SOD↑, *lipid-P↓,
7958- BuckWS,    A new "functional" pasta containing tartary buckwheat sprouts as an ingredient improves the oxidative status and normalizes some blood pressure parameters in spontaneously hypertensive rats
- in-vivo, Nor, NA
*Dose↝, *antiOx↑, *BP↓,
7959- BuckWS,    Impact of Tartary Buckwheat Sprout Flour on Dough Rheological Properties and Quality of Cooked Noodles
- Study, Nor, NA
*Dose↝,
7960- BuckWS,    Tartary buckwheat sprout powder lowers plasma cholesterol level in rats
- in-vivo, Nor, NA
*LDL↓, *Dose↑, *cardioP↑,
7922- BuckWS,  isoO,  VT,  IVT,  RT  Comparison of phenolic compositions between common and tartary buckwheat (Fagopyrum) sprouts
- Review, Nor, NA
*Dose↝, *eff↝, *antiOx↑,
7924- BuckWS,    Antioxidant activity of tartary (Fagopyrum tataricum (L.) Gaertn.) and common (Fagopyrum esculentum moench) buckwheat sprouts
- Review, Nor, NA
*eff↑, *IronCh↑, *H2O2↓,
7923- BuckWS,  isoO,  VT,  IVT,  RT  Flavonoid analysis of buckwheat sprouts
- Review, Nor, NA
*Dose↝,
7967- BUL,    Mode of action of bullatacin: a potent antitumor and pesticidal annonaceous acetogenin
- in-vivo, Ovarian, A2780S - in-vivo, AML, L1210
compI↓, ETC↓,
7971- BUL,    Annonacin, a lipophilic inhibitor of mitochondrial complex I, induces nigral and striatal neurodegeneration in rats: possible relevance for atypical parkinsonism in Guadeloupe
- in-vivo, Park, NA
*Risk↑,
7970- BUL,    Bullatacin triggers immunogenic cell death of colon cancer cells by activating endoplasmic reticulum chaperones
- in-vitro, Colon, SW480 - in-vitro, Colon, HT-29
Apoptosis↑, ICD↑, e-CRT↑, e-HSP90↑, ER Stress↑, e-HMGB1↑, e-HSP70/HSPA5↑, e-HSP90↑, CHOP/DDIT3↑, eff↑,
7972- BUL,    Mode of action of bullatacin, a potent antitumor acetogenin: inhibition of NADH oxidase activity of HeLa and HL-60, but not liver, plasma membranes
- vitro+vivo, Cerv, HeLa - vitro+vivo, AML, HL-60
NADH↓, selectivity↑,
7973- BUL,    Bullatacin, a potent antitumor annonaceous acetogenin, inhibits proliferation of human hepatocarcinoma cell line 2.2.15 by apoptosis induction
- in-vitro, Liver, HepG2
Apoptosis↑, TumCP↓,
7974- BUL,    Selective action of acetogenin mitochondrial complex I inhibitors
- in-vitro, Colon, SW480
compI↓, NADH↓,
7975- BUL,    Bullatacin--in vivo and in vitro experience in an ovarian cancer model
- in-vitro, Ovarian, OVCAR-3
toxicity↝, TumCD↑,
7976- BUL,    Antitumor activity and toxicity relationship of annonaceous acetogenins
- in-vitro, HCC, H22
toxicity↓, TumCG↓, *toxicity↑, *ROS↑, *Ca+2↑, *BAX↑,
7977- BUL,    Mitochondria-mediated apoptosis induced by acetogenins from Porcelia macrocarpa (Annonaceae) in K562 chronic myeloid leukemia cells
- in-vitro, AML, K562
compI↓, tumCV↓, SOD2↑, MMP↓, Ca+2↝, Casp3↑, Casp9↑,
7978- BUL,    Synthesis and Cytotoxic Property of Annonaceous Acetogenin Glycoconjugates
- in-vitro, Cerv, HeLa - in-vitro, Lung, A549 - in-vitro, Liver, HepG2
*toxicity↑, *BioAv↑,
7969- BUL,    Bullatacin triggered ABCB1-overexpressing cell apoptosis via the mitochondrial-dependent pathway
- NA, Cerv, KBv200
ROS↑, MMP↓, cl‑Casp3↑, cl‑Casp9↓, cl‑PARP↑, Cyt‑c↑, eff↓,
7968- BUL,    The Annonaceous acetogenin bullatacin is cytotoxic against multidrug-resistant human mammary adenocarcinoma cells
- in-vitro, BC, MCF7
eff↑, ATP↓,
5745- Buty,    Microbial Oncotarget: Bacterial-Produced Butyrate, Chemoprevention and Warburg Effect
- Review, Var, NA
selectivity↑, HDAC↓, TumCP↓, Apoptosis↑, Warburg↓, chemoPv↑,
5744- Buty,  PacT,    Oral sodium butyrate supplementation ameliorates paclitaxel-induced behavioral and intestinal dysfunction
- in-vivo, Var, NA
chemoP↑, neuroP↑, Inflam↓, GutMicro↑, *ROS↓, Dose↝,
5743- Buty,    Regulation of Intestinal Butyrate Transporters by Oxidative and Inflammatory Status
- Review, Var, NA
*GutMicro↑, *other↑, *Inflam↓, *ROS↓, AntiCan↑, HCAR2↑, HDAC↓,
5742- Buty,    Butyrate: A Double-Edged Sword for Health?
- Review, Var, NA
HCAR2↑, Inflam↓, HDAC↓, *IFN-γ↓, *TNF-α↓, *IL1β↓, *IL6↓, *IL8↓, *IL10↑, *LTA/TNF-β↑, *NF-kB↓, *ROS↓, PPARγ↓, Weight↓,
5741- Buty,  Rad,    Microencapsulated Sodium Butyrate in the Prevention of Acute Radiotherapy Proctitis: Single-Center Prospective Study
- in-vivo, Pca, NA
Dose↝, radioP↑, Pain↓,
5740- Buty,    A Review of Nutritional Regulation of Intestinal Butyrate Synthesis: Interactions Between Dietary Polysaccharides and Proteins
- Review, RCC, NA
*eff↓, Dose↝, eff↑, HDAC↓, ac‑H3↓, ac‑H4↓, *HCAR2↑, *Inflam↓, *ROS↓, *NRF2↑, *GSH↑, *CLDN1↑, *ZO-1↑, IL1β↓, IL6↓, COX2/PTGS2↓, eff↝, eff↑, other↝,
5739- Buty,    Butyrate as a promising therapeutic target in cancer: From pathogenesis to clinic (Review)
- Review, Var, NA
GutMicro↑, *Inflam↓, *IL6↓, *TNF-α↓, *IL17↓, *IL10↑, *ROS↝, COX2/PTGS2↓, NLRP3↓, Imm↑, HDAC↓, TumCCA↑, Apoptosis↑, ROS↑, Casp↑, mtDam↑, Cyt‑c↑, eff↑, chemoP↑, ChemoSen↑, eff↑, RadioS↑, HCAR2↑,
5736- Buty,    Clinical and pharmacologic study of tributyrin: an oral butyrate prodrug
- Trial, Var, NA
Dose↝, BioAv↝, toxicity↓, OS↝,
5738- Buty,    Butyrate’s role in human health and the current progress towards its clinical application to treat gastrointestinal disease
- Review, Nor, NA
*GutMicro↑, *Risk↓,
5735- Buty,    Butyrate and the Intestinal Epithelium: Modulation of Proliferation and Inflammation in Homeostasis and Disease
- Study, Nor, NA
*Inflam↓, GutMicro↑, Imm↑,
5734- Buty,    Enhanced production of IL-18 in butyrate-treated intestinal epithelium by stimulation of the proximal promoter region
- vitro+vivo, Nor, NA
*IL18↑,
5733- Buty,  VitB3,    Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis
- in-vivo, CRC, NA
GutMicro↑, HCAR2↑, AntiCan↑, Inflam↓, IL18↑,
5732- Buty,    GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon
- Study, CRC, NA
HCAR2↑, other↓, Apoptosis↑, HDAC↓, Bcl-2↓, Bcl-xL↓, cycD1/CCND1↓, DR5↑, NF-kB↓, GutMicro↑, SLC12A5↝,
5731- Buty,    The Warburg Effect Dictates the Mechanism of Butyrate Mediated Histone Acetylation and Cell Proliferation
- in-vitro, CRC, HCT116 - in-vitro, CRC, HT29
HDAC↓, Warburg↓, TumCP⇅, HATs↑, BioAv↓, other↝, Risk↓,
5737- Buty,    Butyrate Suppresses the Proliferation of Colorectal Cancer Cells via Targeting Pyruvate Kinase M2 and Metabolic Reprogramming
- in-vitro, CRC, HCT116
HDAC↓, TumCP↓, PKM2↑, Warburg↓,
1080- Buty,    Butyrate suppresses Cox-2 activation in colon cancer cells through HDAC inhibition
- in-vitro, CRC, HT-29
HDAC↓, TNF-α↓, COX2/PTGS2↓,
1032- Buty,    Gut microbiome-derived butyrate inhibits the immunosuppressive factors PD-L1 and IL-10 in tumor-associated macrophages in gastric cancer
- in-vivo, GC, AGS
GutMicro↑, PD-L1↓, IL10↓, TumCG↓,
2050- Buty,    The Role of Sodium Phenylbutyrate in Modifying the Methylome of Breast Cancer Cells
- in-vitro, BC, MCF7
eff↑, HDAC↓, TumCG↓,
2047- Buty,    Sodium butyrate inhibits migration and induces AMPK-mTOR pathway-dependent autophagy and ROS-mediated apoptosis via the miR-139-5p/Bmi-1 axis in human bladder cancer cells
- in-vitro, CRC, T24/HTB-9 - in-vitro, Nor, SV-HUC-1 - in-vitro, Bladder, 5637 - in-vivo, NA, NA
HDAC↓, AntiTum↑, TumCMig↓, AMPK↑, mTOR↑, TumAuto↑, ROS↑, miR-139-5p↑, BMI1↓, TumCI?, E-cadherin↑, N-cadherin↓, Vim↓, Snail↓, cl‑PARP↑, cl‑Casp3↑, BAX↑, Bcl-2↓, Bcl-xL↓, MMP↓, PINK1↑, PARK2↑, TumMeta↓, TumCG↓, LC3II↑, p62↓, eff↓,
1224- Buty,    Intratumor microbiome-derived butyrate promotes lung cancer metastasis
- in-vivo, Lung, NA
TumCG↑, H19↑, HDAC2↓,
1230- CA,  Caff,    Caffeine and Caffeic Acid Inhibit Growth and Modify Estrogen Receptor and Insulin-like Growth Factor I Receptor Levels in Human Breast Cancer
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231 - Human, NA, NA
TumVol↓, TumCG↓, ER(estro)↓, cycD1/CCND1↓, IGF-1R↓, p‑Akt↓,
1207- CA,  PacT,    Caffeine inhibits the anticancer activity of paclitaxel via down-regulation of α-tubulin acetylation
- in-vitro, Lung, A549 - in-vitro, Cerv, HeLa
TumCG↑, TumCMig↓, Apoptosis↓, ac‑α-tubulin↑,
1651- CA,  PBG,    Caffeic acid and its derivatives as potential modulators of oncogenic molecular pathways: New hope in the fight against cancer
- Review, Var, NA
Apoptosis↑, TumCCA↓, TumCMig↓, TumMeta↓, ChemoSen↑, eff↑, eff↑, eff↓, eff↝, Dose∅, AMPK↑, p62↓, LC3II↑, Ca+2↑, Bax:Bcl2↑, CDK4↑, CDK6↑, RB1↑, EMT↓, E-cadherin↑, Vim↓, β-catenin/ZEB1↓, NF-kB↓, angioG↑, VEGF↓, TSP-1↑, MMP9↓, MMP2↓, ChemoSen↑, eff↑, ROS↑, CSCs↓, Fas↑, P53↑, BAX↑, Casp↑, β-catenin/ZEB1↓, NDRG1↑, STAT3↓, MAPK↑, ERK↑, eff↑, eff↑, eff↑,

Showing Research Papers: 1801 to 1850 of 8263
Prev Page 37 of 166 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 8263

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

compI↓, 3,   ICD↑, 1,   NADH↓, 2,   PARK2↑, 1,   ROS↑, 4,   SOD2↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 1,   ETC↓, 1,   MMP↓, 3,   mtDam↑, 1,   PINK1↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 2,   PKM2↑, 1,   PPARγ↓, 1,   Warburg↓, 3,  

Cell Death(tgid=5) ⓘ

p‑Akt↓, 1,   Apoptosis↓, 1,   Apoptosis↑, 6,   BAX↑, 2,   Bax:Bcl2↑, 1,   Bcl-2↓, 2,   Bcl-xL↓, 2,   Casp↑, 2,   Casp3↑, 1,   cl‑Casp3↑, 2,   Casp9↑, 1,   cl‑Casp9↓, 1,   Cyt‑c↑, 2,   DR5↑, 1,   Fas↑, 1,   MAPK↑, 1,   TumCD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HCAR2↑, 5,  

Transcription & Epigenetics(tgid=7) ⓘ

H19↑, 1,   ac‑H3↓, 1,   ac‑H4↓, 1,   HATs↑, 1,   other↓, 1,   other↝, 2,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,   e-CRT↑, 1,   ER Stress↑, 1,   e-HSP70/HSPA5↑, 1,   e-HSP90↑, 2,  

Autophagy & Lysosomes(tgid=9) ⓘ

LC3II↑, 2,   p62↓, 2,   TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

P53↑, 1,   cl‑PARP↑, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK4↑, 1,   cycD1/CCND1↓, 2,   RB1↑, 1,   TumCCA↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMI1↓, 1,   CSCs↓, 1,   EMT↓, 1,   ERK↑, 1,   HDAC↓, 11,   HDAC2↓, 1,   IGF-1R↓, 1,   mTOR↑, 1,   STAT3↓, 1,   TumCG↓, 5,   TumCG↑, 2,  

Migration(tgid=13) ⓘ

Ca+2↑, 1,   Ca+2↝, 1,   E-cadherin↑, 2,   miR-139-5p↑, 1,   MMP2↓, 1,   MMP9↓, 1,   N-cadherin↓, 1,   Snail↓, 1,   TSP-1↑, 1,   TumCI?, 1,   TumCMig↓, 3,   TumCP↓, 3,   TumCP⇅, 1,   TumMeta↓, 2,   Vim↓, 2,   ac‑α-tubulin↑, 1,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

SLC12A5↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 3,   HCAR2↑, 5,   e-HMGB1↑, 1,   IL10↓, 1,   IL18↑, 1,   IL1β↓, 1,   IL6↓, 1,   Imm↑, 2,   Inflam↓, 3,   NF-kB↓, 2,   PD-L1↓, 1,   TNF-α↓, 1,  

Protein Aggregation(tgid=19) ⓘ

NLRP3↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CDK6↑, 1,   ER(estro)↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↝, 1,   ChemoSen↑, 3,   Dose↝, 4,   Dose∅, 1,   eff↓, 3,   eff↑, 13,   eff↝, 2,   RadioS↑, 1,   selectivity↑, 2,  

Clinical Biomarkers(tgid=22) ⓘ

GutMicro↑, 6,   IL6↓, 1,   PD-L1↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 2,   AntiTum↑, 1,   chemoP↑, 2,   chemoPv↑, 1,   NDRG1↑, 1,   neuroP↑, 1,   OS↝, 1,   Pain↓, 1,   radioP↑, 1,   Risk↓, 1,   toxicity↓, 2,   toxicity↝, 1,   TumVol↓, 1,   Weight↓, 1,  
Total Targets: 128

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

ACE/ACE1↓, 1,   Stroke↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 2,   Catalase↑, 1,   Fenton↓, 1,   GPx↑, 1,   GSH↑, 2,   H2O2↓, 1,   lipid-P↓, 2,   NRF2↑, 1,   ROS↓, 7,   ROS↑, 1,   ROS↝, 1,   SOD↑, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 3,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

LDL↓, 2,  

Cell Death(tgid=5) ⓘ

BAX↑, 1,   iNOS↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HCAR2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 3,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,   DNArepair↑, 1,  

Migration(tgid=13) ⓘ

Ca+2↑, 1,   CLDN1↑, 1,   ZO-1↑, 1,  

Barriers & Transport(tgid=15) ⓘ

GastroP↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   HCAR2↑, 1,   IFN-γ↓, 1,   IL10↑, 2,   IL17↓, 1,   IL18↑, 1,   IL1β↓, 1,   IL6↓, 3,   IL8↓, 1,   Inflam↓, 5,   LTA/TNF-β↑, 1,   NF-kB↓, 1,   TNF-α↓, 3,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 1,   Dose?, 1,   Dose↑, 3,   Dose↝, 5,   eff↓, 1,   eff↑, 6,   eff↝, 3,  

Clinical Biomarkers(tgid=22) ⓘ

BP↓, 2,   GutMicro↑, 2,   IL6↓, 3,  

Functional Outcomes(tgid=23) ⓘ

AntiDiabetic↑, 1,   cardioP↑, 2,   hepatoP↑, 1,   Risk↓, 1,   Risk↑, 1,   toxicity↑, 2,  
Total Targets: 57

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
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