Imm Cancer Research Results

Imm, immunostimulatory: Click to Expand ⟱
Source:
Type:
Enhance the immune response in patients.
Scientific Papers found: Click to Expand⟱
8005- JG,    Immunomodulation by juglone alleviates acute graft-versus-host disease without compromising the graft-versus-leukaemia activity in mice
- in-vivo, AML, NA
DCells↓, CD4+↓, OS↑, Imm↝,
8055- KAE,    Molecular Mechanisms of the Anticancer Activity of the Flavonoid Kaempferol: A Comprehensive Review
- Review, Var, NA
antiNeop↑, *toxicity↓, TumCCA↑, ROS↑, ER Stress↑, TumAuto↑, Pyro↑, Ferroptosis↑, angioG↓, Imm↝, eff↑, ChemoSen↑, MPT↑, MMP↓, mtDam↑, Cyt‑c↑, Bax:Bcl2↑, Fas↑, DR4↑, DR5↑, JNK↑, ERK↑, CHOP/DDIT3↑, ER Stress↑, UPR↑, Ca+2↑, PI3K↓, Akt↓, mTOR↓, AMPK↑, *Ferroptosis↓, *antiOx↑, *NRF2↑, *GPx4↑, *ROS↓, *MDA↓, *i-Iron↓, *xCT/SLC7A11↑, VEGF↓, Wnt↓, β-catenin/ZEB1↓, EMT↓, STAT3↓, M2 MC↓, MCP1/CCL2↓, MMP9↓, MMP2↓, TIMP2↓, ChemoSen↑, PKM2↑, Glycolysis↓, CSCs↓, SOX4↓, OCT4↓, CD44↓, Nanog↓, MDR1↓, *GutMicro↑,
8122- LA,  ProBio,    Probiotics in colorectal cancer: mechanisms, biomarkers, and adjunct strategies
- Review, CRC, NA
GutMicro↑, IBI↑, TumCG↓, Inflam↓, Imm↝, eff↑,
8163- LapC,    Lapachol, a compound targeting pyrimidine metabolism, ameliorates experimental autoimmune arthritis
- in-vivo, Arthritis, NA
*DHODH↓, *Imm↓, AntiArt↑, antiPs↑, BioAv↝,
8235- LCA,    Anticancer effects of licochalcones: A review of the mechanisms
- Review, Var, NA
mt-Apoptosis↑, TumAuto↑, TumCMig↓, LC3‑Ⅱ/LC3‑Ⅰ↑, ATG5↑, ATG7↑, p62↑, CHOP/DDIT3↑, ER Stress↑, UPR↑, ATG3↑, Beclin-1/ATG6↑, ATG16L1↑, PERK↑, ATF4↑, ATP↓, Hif1a↓, GLUT1↓, PDK1 / PDPK1↓, Bcl-xL↓, Bcl-2↓, BAD↑, BAX↑, Casp3↑, survivin↓, EGFR↓, ERK↓, Akt↓, mtDam↑, MMP↓, Cyt‑c↑, Casp↑, MDM2↓, CycB/CCNB1↓, CDC2↓, CDC25↓, TumCCA↑, TumCP↓, Wnt↓, β-catenin/ZEB1↓, Sp1/3/4↓, MMP-10↓, MMP3↓, TumCI↓, Imm↑, PD-L1↓, ROS↑, 4E-BP1↓, eIF2α↓, PI3K↓, mTOR↓, p‑cMET↑, Ca+2↑, RUBCN↓, ATG13↑, TSC1↑, TSC2↑, PRAS40↑, PP2A↑, ULK1/ATG1↑, THEM4/CTMP↑, DR5↑, Fas↑, TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, PKCδ↓, P70S6K↓, VEGF↓, angioG↓, HK2↓, Glycolysis↓, TrxR1↓, APAF1↑, cl‑PARP↑, Bax:Bcl2↑, ABCG2↓, BioEnh↑,
8237- LCA,    Role of Licochalcone A in Potential Pharmacological Therapy: A Review
- Review, Var, NA
*other↝, *Inflam↓, *Bacteria↓, *antiOx↑, *AntiP↑, *neuroP↑, *glucose↝, *lipid-P↓, PKCδ↓, P70S6K↓, Akt↓, ER Stress↑, Apoptosis↑, Ca+2↑, PI3K↓, mTOR↓, Casp3↑, Bcl-2↓, Cyt‑c↑, BAX↑, cl‑PARP↑, cycD1/CCND1↑, ROS↑, CHOP/DDIT3↑, ERK↑, p38↑, JNK↓, IAP1↓, XIAP↓, survivin↓, cFLIP↓, RIP1↓, EGFR↓, MET↓, HER2/EBBR2↓, p‑4E-BP1↓, PERK↑, eIF2α↑, PD-L1↓, HK2↓, Glycolysis↓, Sp1/3/4↓, FasL↑, MMP↓, ATP↓, TumAuto↑, WEE1↑, P21↑, CDK1↓, TumCCA↑, TumCMig↓, TumCI↓, ABCG2↓, HSP90↓, T-Cell↑, CD4+↑, CD25+↑, FOXP3↑, Imm↝, *Inflam↓, *NF-kB↓, *NRF2↑, *AntiArt↑,
8145- LF,    Neuroprotective Effects of Lactoferrin in Alzheimer's and Parkinson's Diseases: A Narrative Review
- Review, AD, NA - Review, Park, NA
*AntiBio↑, *Imm↑, *AntiCan↑, *neuroP↑, *BBB↑, *APOE4↓, *ROS↓, *Inflam↓, *Apoptosis↓, *Learn↑, *memory↑, *ADAM10↑, *PSEN1/PS1↑, *cl‑APP↑, *BACE/β-secretase↓, *cognitive↑, *MDA↓, *IL6↓, *TNF-α↓, *neuroP↑, *Dose↝, *IronCh↑, *SOD↑, *BioAv↝,
8124- LF,    Inhibition of intestinal polyp growth by oral ingestion of bovine lactoferrin and immune cells in the large intestine
- Trial, CRC, NA
Risk↓, Dose↝, NK cell↑, Neut↑, CD4+↑, Imm↑, APG↓,
8127- LF,    Phase I trial of oral talactoferrin alfa in refractory solid tumors
- Trial, Var, NA
Imm↑, NK cell↑, Dose↝, toxicity↓, IL18↑, SD↑, TumCG↓, OS↑,
8128- LF,    Phase 2 trial of talactoferrin in previously treated patients with metastatic renal cell carcinoma
- Trial, RCC, NA
Imm↑, NK cell↑, Dose↝, toxicity↓, PFS↑,
8129- LF,    Study on the Therapeutic Benefit on Lactoferrin in Patients with Colorectal Cancer Receiving Chemotherapy
- Trial, CRC, NA
Dose↝, toxicity↓, INF-γ↝, other↑, *ROS↓, Imm↑, WBC↑, Neut↑, T-Cell↑, *antiOx↑, *GSH↑, *chemoP↑, *RenoP↑, *hepatoP↑, BUN↓, creat↓, ALAT↓, AST↓, RBC↑, PC↑, Mucositis↓, *AntiBio↑, *AntiViral↑, *AntiFungal↑, *Inflam↓,
8135- LF,    Lactoferrin-A Regulator of Iron Homeostasis and Its Implications in Cancer
- Review, Var, NA - Review, AD, NA
IronCh↑, ROS↓, Imm↑, Inflam↓, *BBB↑, Iron↝, *Fenton↓, *ROS↓, *TAC↑, *SOD↑, *GPx↑, *GSH↑, *TBARS↓, *PTEN↓, *tau↓, *MAPK↓, *Aβ42↓, *Apoptosis↓, *Casp3↓, *Akt↑, *GutMicro↑, *Sepsis↓, *anemia↓, *IL6↓, *FPN↑, *TfR1/CD71↑, *Ferritin↓, *HemoG↑, *RBC↑, *eff↑, *BioAv↓, *BioAv↑, *BioAv↝, *ChemoSen↑, *BioAv↑, Ferroptosis↑,
8141- LF,    Controversial role of lactoferrin in cancer: A narrative review
- Review, Var, NA
*AntiBio↑, *antiOx↑, *Inflam↓, *Imm↑, *AntiCan↑, TumMeta↑,
8137- LF,    Lactoferrin delivery systems: approaches for its more effective use
- Review, IBD, NA
*Imm↑, *BioAv↓, *BioAv↑,
7824- MBS,  IVT,  VT,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA - Review, Stroke, NA - Review, Park, NA
*neuroP↑, *Aβ↓, *p‑tau↓, *ROS↓, *Inflam↓, *AChE↓, *BBB↑, *memory↑, *hepatoP↑, *Imm↑, *hyperG↓, *AntiCan↑, *eff↑, *Stroke↓, *BACE/β-secretase↓, *PI3K↓, *Akt↓, *mTOR↓, *Dose↓,
5800- MET,    Metformin as anticancer agent and adjuvant in cancer combination therapy: Current progress and future prospect
- Review, Var, NA
ChemoSen↑, RadioS↑, Imm↑, *AntiDiabetic↑, *AMPK↑, TumCP↓, hepatoP↑, ATP↓, AMP↑, glucoNG↓, ROS↑, compI↓, DNAdam↑, CSCs↓, NP/CIPN↓, chemoP↑, toxicity↓, Trx↓, eff↑, cycD1/CCND1↓, CDK4↓, CDK6↓, cycE/CCNE↓, CDK2↓,
4092- MF,    Mechanisms and therapeutic effectiveness of pulsed electromagnetic field therapy in oncology
- Review, Var, NA
Apoptosis↑, selectivity↑, ROS↑, Catalase↓, TumVol↓, angioG↓, Ca+2↝, eff↝, angioG↓, Imm↝, TNF-α↑, Casp8↑,
200- MFrot,  MF,    Moderate intensity low frequency rotating magnetic field inhibits breast cancer growth in mice
- in-vivo, BC, MDA-MB-231 - in-vivo, BC, MCF7
ALAT↓, TumVol↓, TumCCA↑, TumCG↓, TumMeta↓, Imm↑, P53↑, ALAT↓, AST↓,
198- MFrot,  MF,    Biological effects of rotating magnetic field: A review from 1969 to 2021
- Review, Var, NA
AntiCan↑, breath↑, Pain↓, Appetite↑, Strength↑, BowelM↑, TumMeta↓, TumCCA↑, ETC↓, MMP↓, TumCD↑, selectivity↑, ROS↑, Casp3↑, TumCG↓, TumCCA↑, ChrMod↑, TumMeta↓, Imm↑, DCells↑, Akt↓, OS⇅, toxicity↓, QoL↑, hepatoP↑, Pain↓, Weight↑, Strength↑, Sleep↑, IL6↓, CD4+↑, CD8+↑, Ca+2↑, radioP↑, chemoP↑, *BMD↑, *AntiAge↑, *AMPK↑, *P21↓, *P53↓, *mTOR↓, *OS↑, *β-Endo↑, *5HT↓,
5611- NaHCO3,    NaHCO3 enhances the antitumor activities of cytokine-induced killer cells against hepatocellular carcinoma HepG2 cells
- vitro+vivo, HCC, HepG2
tumCV↓, TumCG↓, pH↑, eff↑, Imm↑,
5617- NaHCO3,    Microenvironmental alkalization promotes the therapeutic effects of MSLN-CAR-T cells
- vitro+vivo, NA, NA
Imm↑, eff↑, pH↑,
5612- NaHCO3,  immuno,    Neutralization of tumor acidity improves anti-tumor responses to immunotherapies
- vitro+vivo, Var, B16-F10
Imm↑, eff↑, e-pH↑, TumCG↓, TumMeta↓, eff↑,
5610- NaHCO3,  doxoR,    Sodium bicarbonate nanoparticles modulate the tumor pH and enhance the cellular uptake of doxorubicin
- vitro+vivo, BC, 4T1
pH↑, Imm↑, eff↑, ChemoSen↑, TumVol↓, eff↑,
5608- NaHCO3,    Sodium Bicarbonate Nanoparticles for Amplified Cancer Immunotherapy by Inducing Pyroptosis and Regulating Lactic Acid Metabolism
- Study, Var, NA
TumCG↓, TumMeta↓, e-pH↑, Pyro↑, Imm↑, Na+↑,
5604- NaHCO3,    Mitochondrial metabolic reprogramming of macrophages and T cells enhances CD47 antibody-engineered oncolytic virus antitumor immunity
- vitro+vivo, Melanoma, B16-BL6 - in-vitro, BC, 4T1
eff↑, eff↑, TumMeta↓, pH↑, CaMKII ↑, CREB↑, PGC-1α↑, AntiTum↑, Imm↑, CD8+↑, TAMS↑,
6775- Neem,  Nimb,    Therapeutics Role of Azadirachta indica (Neem) and Their Active Constituents in Diseases Prevention and Treatment
- Review, Nor, NA
*antiOx↑, P53↑, PTEN↑, NF-kB↓, PI3K↓, Akt↓, Bcl-2↓, VEGF↓, *Inflam↓, *COX2/PTGS2↓, *5LO↝, *Wound Healing↑, *Imm↑, *hepatoP↑, *AntiDiabetic↑, *neuroP↑, *AntiViral↑, *Bacteria↑, *AntiBio↑, *AntiFungal↑, cMyc↓, BAX↓, IAP1↓, IAP2/BIRC3↓, Bcl-xL↓, survivin↓, XIAP↓, angioG↓,
5936- P,    The impact of peppermint oil on the irritable bowel syndrome: a meta-analysis of the pooled clinical data
- Review, IBD, NA
*Pain↓, *other↝, *Bacteria↓, *Inflam↓, *Imm↑, *eff↑, *toxicity↓,
5209- PI,    Piperine depresses the migration progression via downregulating the Akt/mTOR/MMP-9 signaling pathway in DU145 cells
- in-vitro, Pca, DU145
TumCP↓, TumCMig↓, Apoptosis↑, p‑Akt↓, MMP9↓, p‑mTOR↓, TumMeta↓, *antiOx↓, *Inflam↓, *hepatoP↑, *Imm↑, *AntiCan↑,
6220- Se,  CUR,  Rad,    Selenium-Curcumin-PEG Nanoparticles Radiosensitization for Intensity-Modulated Radiation Therapy of Lung Tumor Cells: In Vitro Synergistic Combination Therapy
- in-vitro, Lung, A549
RadioS↑, TumCD↑, ROS↑, Imm↑, angioG↓, BioAv↑, TumCP↓, Apoptosis↓, TumMeta↓,
4485- Se,    Selenium stimulates the antitumour immunity: Insights to future research
- Review, NA, NA
*antiOx↑, chemoPv↑, ROS↑, Imm↑, selenoP↑, *IL2↑, *IL4↑, *TNF-α↓, *TGF-β↓, *EMT↓, Risk↓, *GPx↑, *TrxR↑,
4608- SeNPs,    Selenium Nanoparticles for Biomedical Applications: From Development and Characterization to Therapeutics
- Review, Var, NA - NA, AD, NA
*toxicity↝, *toxicity↓, *other↝, ROS↑, *Dose↝, *selenoP↑, AntiCan↑, AntiTum↑, *Bacteria↓, *radioP↑, *BioAv↑, *Inflam↓, *Imm↑, ChemoSen↑, *AntiAg↑, selectivity↑, eff↑, other↝, *eff↑, *Aβ↓, *eff↑,
4603- SeNPs,    Therapeutic applications of selenium nanoparticles
- Review, Var, NA
AntiCan↑, Imm↑, *AntiDiabetic↑, *antiOx↑, *Inflam↓, ROS↑, ER Stress↑, DNAdam↑, *toxicity↓, *eff↑, *BioAv↑, selectivity↑, TumCCA↑, Risk↓, *lipid-P↓, *TNF-α↓, *CRP↓, TumMeta↓, angioG↓, selectivity↑, eff↑, *eff↑,
4742- SSE,    Antitumor Effects of Selenium
- Review, Var, NA - Review, Arthritis, NA - Review, Sepsis, NA
*antiOx↓, *Inflam↓, Risk↓, TumCI↓, TumMeta↓, radioP↑, chemoP↑, Apoptosis↑, ROS↑, DNAdam↑, Dose↑, selectivity↑, *other↓, *BioAv↑, ROS↑, MMP↓, Casp↑, *Imm↑, *Pain↓, Sepsis↓, MMP2↓, MMP9↓, *Half-Life↓,
5074- SSE,    Application of Sodium Selenite in the Prevention and Treatment of Cancers
- Review, Var, NA
Imm↑, angioG↑, DNArepair↑, NK cell↑, ROS↑, AntiCan↑, selectivity↑, ER Stress↑, TumAuto↑, necrosis↑, toxicity↝, Dose↑,
5082- SSE,    Rationale for the treatment of cancer with sodium selenite
- Review, Var, NA
Risk↑, antiOx↑, ROS↑, Imm↑, NK cell↑, angioG↓, toxicity↓,
5087- SSE,    Sodium Selenite Alleviates Breast Cancer-Related Lymphedema Independent of Antioxidant Defense System
- Trial, BC, NA
eff↑, Inflam↓, Imm↑, ROS↑, *NK cell↑,
4498- SSE,    Selenium in Human Health and Gut Microflora: Bioavailability of Selenocompounds and Relationship With Diseases
- Review, Var, NA - Review, AD, NA - Review, IBD, NA
*Imm↑, *GutMicro↑, *BioAv↑, *Risk↓, *Dose↝, Risk↓, *CRP↓, *GPx↓, *Inflam↓, *selenoP↑, *Dose↝, *ROS↓, *MDA↓, *SOD↑, *GPx↑, *IL1↓, *MCP1/CCL2↓, *IL6↓, *TNF-α↓, Risk↓, *neuroP↑, *memory↑,
6767- Thyme,    Thymol, thyme, and other plant sources: Health and potential uses
- Review, Nor, NA
*AntiBio↑, *Inflam↓, *Imm↑, *other↝, *Half-Life↝, *Obesity↓, *GutMicro↑,
5904- TV,    Pharmacological Properties and Molecular Mechanisms of Thymol: Prospects for Its Therapeutic Potential and Pharmaceutical Development
- Review, Var, NA - Review, Stroke, NA - Review, Diabetic, NA - Review, Obesity, NA - Review, AD, NA - Review, Arthritis, NA
*antiOx↑, *ROS↓, *Inflam↓, *Bacteria↓, AntiTum↑, IronCh↑, *HDL↑, *LDL↓, *BioAv↝, *Half-Life↝, *BioAv↑, *SOD↑, *GPx↑, *GSTs↑, *eff↑, radioP↑, *MDA↓, *other↑, *COX1↓, *COX2/PTGS2↓, *AntiAg↑, *RNS↓, *NO↓, *H2O2↓, *NOS2↓, *NADH↓, *Imm↑, Apoptosis↑, TumCP↓, angioG↓, TumCMig↓, Ca+2↑, TumCCA↑, DNAdam↑, BAX↑, Casp9↑, Casp8↑, Casp3↑, cl‑PARP↑, AIF↑, i-ROS↑, MMP↓, Cyt‑c↑, APAF1↑, Ca+2↑, MMP9↓, MMP2↓, PKCδ↓, ERK↓, H2O2↑, BAX↑, Bcl-2↓, DNAdam↑, lipid-P↑, ChemoSen↑, chemoP↑, *cardioP↑, *SOD↑, *Catalase↑, *GPx↑, *GSH↑, *BP↓, *AntiDiabetic↑, *Obesity↓, RenoP↑, *GastroP↑, hepatoP↑, *AChE↓, *cognitive↑, *BChE↓, *other↓, *BioAv↑,
4833- Uro,    Unveiling the potential of Urolithin A in Cancer Therapy: Mechanistic Insights to Future Perspectives of Nanomedicine
- Review, Var, NA - Review, AD, NA - Review, IBD, NA
BioAv↝, TumAuto↝, TumCG↓, TumMeta↓, ChemoSen↑, Imm↑, RadioS↑, BioAv↑, other↝, eff↓, *antiOx↓, *Inflam↓, AntiCan↓, AntiAge↑, chemoP↑, *neuroP↑, *ROS↓, *cognitive↑, *lipid-P↓, *cardioP↑, *TNF-α↓, *IL6↓, GutMicro↑, TumCCA↑, Apoptosis↑, angioG↓, NF-kB↓, PI3K↓, Akt↓, Casp↑, survivin↓, TumCP↓, cycD1/CCND1↓, cMyc↑, BAX↑, Bcl-2↓, COX2/PTGS2↓, P53↑, p38↑, *ROS↓, *SOD↑, *GPx↑, SIRT1↑, FOXO1↑, eff↑, ChemoSen↑,
4885- ZER,    Anti-cancer potential of zerumbone in cancer and glioma: current trends and future perspectives
- Review, Var, NA
AntiTum↑, *Imm↑, AntiCan↑,

Showing Research Papers: 151 to 191 of 191
Prev Page 4 of 4

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 191

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

AntiArt↑, 1,   APG↓, 1,   ATG13↑, 1,   ATG16L1↑, 1,   Mucositis↓, 1,   PC↑, 1,   PFS↑, 1,   RBC↑, 1,   RUBCN↓, 1,   THEM4/CTMP↑, 1,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,   ULK1/ATG1↑, 1,   WBC↑, 1,   WEE1↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   Catalase↓, 1,   compI↓, 1,   Ferroptosis↑, 2,   H2O2↑, 1,   Iron↝, 1,   lipid-P↑, 1,   ROS↓, 1,   ROS↑, 15,   i-ROS↑, 1,   selenoP↑, 1,   Trx↓, 1,   TrxR1↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 1,   ATP↓, 3,   CDC2↓, 1,   CDC25↓, 1,   ETC↓, 1,   MMP↓, 6,   MPT↑, 1,   mtDam↑, 2,   PGC-1α↑, 1,   XIAP↓, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 3,   AMP↑, 1,   AMPK↑, 1,   ATG7↑, 1,   BUN↓, 1,   cMyc↓, 1,   cMyc↑, 1,   CREB↑, 1,   glucoNG↓, 1,   Glycolysis↓, 3,   HK2↓, 2,   PDK1 / PDPK1↓, 1,   PKM2↑, 1,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 6,   p‑Akt↓, 1,   APAF1↑, 2,   Apoptosis↓, 1,   Apoptosis↑, 6,   mt-Apoptosis↑, 1,   BAD↑, 1,   BAX↓, 1,   BAX↑, 5,   Bax:Bcl2↑, 2,   Bcl-2↓, 5,   Bcl-xL↓, 2,   Casp↑, 3,   Casp3↑, 4,   Casp8↑, 2,   Casp9↑, 1,   cFLIP↓, 1,   Cyt‑c↑, 4,   DR4↑, 1,   DR5↑, 2,   Fas↑, 2,   FasL↑, 1,   Ferroptosis↑, 2,   IAP1↓, 2,   IAP2/BIRC3↓, 1,   JNK↓, 1,   JNK↑, 1,   MDM2↓, 1,   necrosis↑, 1,   p38↑, 2,   Pyro↑, 2,   RIP1↓, 1,   survivin↓, 4,   TumCD↑, 2,  

Kinase & Signal Transduction(tgid=6) ⓘ

CaMKII ↑, 1,   HER2/EBBR2↓, 1,   Sp1/3/4↓, 2,   TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

BowelM↑, 1,   ChrMod↑, 1,   other↑, 1,   other↝, 2,   SD↑, 1,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 3,   eIF2α↓, 1,   eIF2α↑, 1,   ER Stress↑, 6,   HSP90↓, 1,   PERK↑, 2,   UPR↑, 2,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG3↑, 1,   ATG5↑, 1,   Beclin-1/ATG6↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   p62↑, 1,   TumAuto↑, 4,   TumAuto↝, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 5,   DNArepair↑, 1,   P53↑, 3,   cl‑PARP↑, 3,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK2↓, 1,   CDK4↓, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 2,   cycD1/CCND1↑, 1,   cycE/CCNE↓, 1,   P21↑, 1,   TumCCA↑, 9,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

4E-BP1↓, 1,   p‑4E-BP1↓, 1,   CD44↓, 1,   p‑cMET↑, 1,   CSCs↓, 2,   EMT↓, 1,   ERK↓, 2,   ERK↑, 2,   FOXO1↑, 1,   mTOR↓, 3,   p‑mTOR↓, 1,   Nanog↓, 1,   OCT4↓, 1,   P70S6K↓, 2,   PI3K↓, 5,   PTEN↑, 1,   STAT3↓, 1,   TumCG↓, 8,   Wnt↓, 2,  

Migration(tgid=13) ⓘ

Ca+2↑, 6,   Ca+2↝, 1,   MET↓, 1,   MMP-10↓, 1,   MMP2↓, 3,   MMP3↓, 1,   MMP9↓, 4,   Na+↑, 1,   PKCδ↓, 3,   SOX4↓, 1,   TIMP2↓, 1,   TSC1↑, 1,   TumCI↓, 3,   TumCMig↓, 4,   TumCP↓, 6,   TumMeta↓, 11,   TumMeta↑, 1,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 10,   angioG↑, 1,   ATF4↑, 1,   EGFR↓, 2,   Hif1a↓, 1,   TAMS↑, 1,   VEGF↓, 3,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↓, 1,   IBI↑, 1,   Na+↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD25+↑, 1,   CD4+↓, 1,   CD4+↑, 3,   COX2/PTGS2↓, 1,   DCells↓, 1,   DCells↑, 1,   FOXP3↑, 1,   IL18↑, 1,   IL6↓, 1,   Imm↑, 22,   Imm↝, 5,   INF-γ↝, 1,   Inflam↓, 3,   M2 MC↓, 1,   MCP1/CCL2↓, 1,   Neut↑, 2,   NF-kB↓, 2,   NK cell↑, 5,   PD-L1↓, 2,   T-Cell↑, 2,   TNF-α↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

pH↑, 4,   e-pH↑, 2,  

Protein Aggregation(tgid=19) ⓘ

PP2A↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CDK6↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 2,   BioAv↑, 2,   BioAv↝, 2,   BioEnh↑, 1,   ChemoSen↑, 8,   Dose↑, 2,   Dose↝, 4,   eff↓, 1,   eff↑, 15,   eff↝, 1,   MDR1↓, 1,   RadioS↑, 3,   selectivity↑, 7,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 3,   AST↓, 2,   creat↓, 1,   EGFR↓, 2,   GutMicro↑, 2,   HER2/EBBR2↓, 1,   IL6↓, 1,   PD-L1↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↓, 1,   AntiCan↑, 5,   antiNeop↑, 1,   antiPs↑, 1,   AntiTum↑, 4,   Appetite↑, 1,   breath↑, 1,   chemoP↑, 5,   chemoPv↑, 1,   hepatoP↑, 3,   NP/CIPN↓, 1,   OS↑, 2,   OS⇅, 1,   Pain↓, 2,   PRAS40↑, 1,   QoL↑, 1,   radioP↑, 3,   RenoP↑, 1,   Risk↓, 6,   Risk↑, 1,   Sleep↑, 1,   Strength↑, 2,   toxicity↓, 6,   toxicity↝, 1,   TumVol↓, 3,   Weight↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

CD8+↑, 2,   Sepsis↓, 1,  
Total Targets: 245

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

anemia↓, 1,   AntiArt↑, 1,   AntiBio↑, 5,   AntiP↑, 1,   APOE4↓, 1,   Aβ42↓, 1,   DHODH↓, 1,   FPN↑, 1,   Learn↑, 1,   PSEN1/PS1↑, 1,   RBC↑, 1,   Stroke↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 3,   antiOx↑, 8,   Catalase↑, 1,   Fenton↓, 1,   Ferroptosis↓, 1,   GPx↓, 1,   GPx↑, 6,   GPx4↑, 1,   GSH↑, 3,   GSTs↑, 1,   H2O2↓, 1,   HDL↑, 1,   hyperG↓, 1,   i-Iron↓, 1,   lipid-P↓, 3,   MDA↓, 4,   NADH↓, 1,   NRF2↑, 2,   RNS↓, 1,   ROS↓, 9,   selenoP↑, 2,   SOD↑, 6,   TAC↑, 1,   TBARS↓, 1,   TrxR↑, 1,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   IronCh↑, 1,   TfR1/CD71↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 2,   glucose↝, 1,   LDL↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   Akt↑, 1,   Apoptosis↓, 2,   Casp3↓, 1,   Ferroptosis↓, 1,   MAPK↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↓, 2,   other↑, 1,   other↝, 4,  

DNA Damage & Repair(tgid=10) ⓘ

P53↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

P21↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

EMT↓, 1,   mTOR↓, 2,   PI3K↓, 1,   PTEN↓, 1,  

Migration(tgid=13) ⓘ

5LO↝, 1,   AntiAg↑, 2,   cl‑APP↑, 1,   TGF-β↓, 1,   β-Endo↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 3,   GastroP↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 1,   COX2/PTGS2↓, 2,   CRP↓, 2,   IL1↓, 1,   IL2↑, 1,   IL4↑, 1,   IL6↓, 4,   Imm↓, 1,   Imm↑, 13,   Inflam↓, 16,   MCP1/CCL2↓, 1,   NF-kB↓, 1,   NK cell↑, 1,   TNF-α↓, 5,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   AChE↓, 2,   ADAM10↑, 1,   BChE↓, 1,   tau↓, 1,   p‑tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 2,   BACE/β-secretase↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↑, 9,   BioAv↝, 3,   ChemoSen↑, 1,   Dose↓, 1,   Dose↝, 4,   eff↑, 8,   Half-Life↓, 1,   Half-Life↝, 2,  

Clinical Biomarkers(tgid=22) ⓘ

BMD↑, 1,   BP↓, 1,   CRP↓, 2,   Ferritin↓, 1,   GutMicro↑, 4,   HemoG↑, 1,   IL6↓, 4,   NOS2↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↑, 4,   AntiDiabetic↑, 4,   cardioP↑, 2,   chemoP↑, 1,   cognitive↑, 3,   hepatoP↑, 4,   memory↑, 3,   neuroP↑, 7,   Obesity↓, 2,   OS↑, 1,   Pain↓, 2,   radioP↑, 1,   RenoP↑, 1,   Risk↓, 1,   toxicity↓, 4,   toxicity↝, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 2,   AntiViral↑, 2,   Bacteria↓, 4,   Bacteria↑, 1,   Sepsis↓, 1,  
Total Targets: 129

Scientific Paper Hit Count for: Imm, immunostimulatory
14 Echinacea
13 beta-glucans
9 chitosan
8 immunotherapy
8 Lactoferrin/Talactoferrin
6 Dandelion Root
6 Electrical Pulses
6 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
6 Bicarbonate(Sodium)
5 Hyperthermia
5 Inositol
5 Selenite (Sodium)
4 Astragalus
4 Curcumin
4 Radiotherapy/Radiation
3 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
3 Bifidobacterium
3 Chemotherapy
3 Centella asiatica / Gotu kola → asiaticoside
3 Chyawanprash
3 Cichoric acid / Chicoric acid
3 diet Fermented Foods
3 Fucoidan
3 Germanium Organic/Ge-132 / propagermanium (organogermanium)
3 Magnetic Fields
2 Aloe anthraquinones
2 Butyrate
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Cat’s Claw
2 Chlorogenic acid
2 Carica papaya leaf extract
2 Cucurbitacin
2 Date Fruit Extract
2 Docosahexaenoic Acid
2 diet Short Term Fasting
2 Disulfiram
2 doxorubicin
2 EGCG (Epigallocatechin Gallate)
2 Emodin
2 Hydrogen Gas
2 Isobavachalcone
2 Inulin Prebiotic
2 Ivermectin
2 Isovitexin
2 Licochalcone A
2 Magnetic Field Rotating
2 Selenium
2 Selenium NanoParticles
1 5-Aminolevulinic acid
1 Photodynamic Therapy
1 Anethole/trans-Anethole
1 Aspirin
1 Astaxanthin
1 Bevacizumab (brand Avastin)
1 Bromelain
1 Boswellia (frankincense)
1 Black phosphorus
1 Bruteridin(bergamot juice)
1 α-Bisabolol / Chamomile oil
1 Caffeic acid
1 Capsaicin
1 Carvacrol
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Celastrol
1 Chlorophyllin
1 Chocolate
1 Carvone
1 diet FMD Fasting Mimicking Diet
1 D-limonene
1 Copper and Cu NanoParticles
1 flavonoids
1 Ginger/6-Shogaol/Gingerol
1 Ginkgetin
1 Gossypol/AT-101
1 hydroxychloroquine
1 Gemcitabine (Gemzar)
1 Paclitaxel/Taxol
1 Helleborus niger extracts – Christmas Rose
1 Honokiol
1 Indole-3-carbinol
1 iodine
1 metronomic chemo
1 Juglone
1 Kaempferol
1 Lactobacillus
1 probiotics
1 Lapachol
1 Mung Bean Sprouts
1 Vitexin
1 Metformin
1 Neem
1 Nimbolide
1 Peppermint
1 Piperine
1 Thyme
1 Thymol-Thymus vulgaris
1 Urolithin
1 Zerumbone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1332  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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