| Source: |
| Type: |
| MDA : malondialdehyde. The level of oxidative stress can be measured by assessing the MDA levels. Since MDA is highly cytotoxic and carcinogenic agent it is frequently used as a biomarker of oxidative stress during major health problems such as cancer, etc. Malondialdehyde (MDA) is the most widely used agent to estimate the extent of lipid peroxidation. Timely diagnosis of the condition followed by supplementation with antioxidants like beta-carotene, pro-vitamin A, vitamin A, vitamin C, vitamin E, lipoic acid, zinc, selenium, and spirulina can prevent potentially malignant disorders. MDA is a lipid peroxidation marker |
| 6981- | Form, | Formononetin: a review of its source, pharmacology, drug combination, toxicity, derivatives, and drug delivery systems |
| - | Review, | Var, | NA | - | Review, | AD, | NA | - | Review, | PSA, | NA |
| 7012- | Fuc, | Fucoidan: A promising natural therapeutic agent for protecting human kidney health |
| - | Review, | EC, | NA |
| 7040- | GA, | Effects of gallic acid on acrylamide-induced endoplasmic reticulum stress, neuroinflammation and neuronal apoptosis in rats |
| - | Trial, | AD, | NA |
| 7046- | GA, | Gallic acid: A promising anti-non-small cell lung cancer compound targeting early growth response protein-1 for apoptosis and ferroptosis |
| - | in-vitro, | NSCLC, | A549 | - | in-vitro, | NSCLC, | H1299 |
| 3723- | GBE, | Can We Use Ginkgo biloba Extract to Treat Alzheimer’s Disease? Lessons from Preclinical and Clinical Studies |
| - | Review, | AD, | NA |
| 7140- | GI, | Benefits of Ginger and Its Constituent 6-Shogaol in Inhibiting Inflammatory Processes |
| - | Review, | Var, | NA |
| - | in-vitro, | CRC, | HT-29 | - | in-vitro, | Nor, | CCD841 |
| 7338- | Gra, | Pharmacological Activities of Soursop (Annona muricata Lin.) |
| - | Review, | Var, | NA |
| 7482- | H2, | Molecular Hydrogen Therapy: Mechanisms, Delivery Methods, Preventive, and Therapeutic Application |
| - | Review, | Var, | NA | - | Review, | IBD, | NA | - | Review, | Stroke, | NA | - | Review, | Sepsis, | NA | - | Review, | AD, | NA |
| 7489- | H2, | Molecular Hydrogen in the Treatment of Respiratory Diseases |
| - | Review, | Asthma, | NA |
| 7492- | H2, | Chemo, | Molecular Hydrogen Protects against Various Tissue Injuries from Side Effects of Anticancer Drugs by Reducing Oxidative Stress and Inflammation |
| - | Review, | Var, | NA |
| 7925- | H2, | Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice |
| - | in-vivo, | Asthma, | NA |
| 7926- | H2, | Hydrogen gas inhalation enhances alveolar macrophage phagocytosis in an ovalbumin-induced asthma model |
| - | in-vivo, | Asthma, | NA |
| 7933- | H2, | Hydrogen inhalation ameliorates lung inflammation in mice with asthma |
| - | in-vivo, | Asthma, | NA |
| 2525- | H2, | Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis |
| - | in-vivo, | NA, | NA |
| 3770- | H2, | Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases |
| - | Review, | AD, | NA | - | Review, | Park, | NA |
| - | Review, | AD, | NA | - | Review, | Stroke, | NA |
| 3764- | H2, | Therapeutic Effects of Hydrogen Gas Inhalation on Trimethyltin-Induced Neurotoxicity and Cognitive Impairment in the C57BL/6 Mice Model |
| - | in-vivo, | AD, | NA |
| 3767- | H2, | The role of hydrogen therapy in Alzheimer's disease management: Insights into mechanisms, administration routes, and future challenges |
| - | Review, | AD, | NA |
| 1635- | HCA, | Hydroxycitric acid prevents hyperoxaluric-induced nephrolithiasis and oxidative stress via activation of the Nrf2/Keap1 signaling pathway |
| - | vitro+vivo, | Nor, | NA |
| 1633- | HCA, | Hydroxycitric Acid Alleviated Lung Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress and Ferroptosis through the Hif-1α Pathway |
| - | in-vivo, | NA, | NA | - | in-vitro, | Nor, | HUVECs |
| 4213- | Hup, | Huperzine A-Liposomes Efficiently Improve Neural Injury in the Hippocampus of Mice with Chronic Intermittent Hypoxia |
| - | in-vivo, | NA, | NA |
| 7565- | HYP, | Potential Implications of Hyperoside on Oxidative Stress-Induced Human Diseases: A Comprehensive Review |
| - | Review, | AD, | NA |
| 7562- | HYP, | doxoR, | Hyperoside Inhibits Doxorubicin-Induced Ferroptosis in Cardiomyocytes via the Nrf2/GPX4 Pathway |
| - | in-vivo, | Nor, | NA |
| 7561- | HYP, | Hyperoside Exerts Therapeutic Effects on Parkinson's Disease by Mitigating Oxidative Stress through Activation of Nrf2/HO-1 Pathway |
| - | in-vivo, | Park, | NA |
| 7560- | HYP, | Hyperoside: A Review of Its Structure, Synthesis, Pharmacology, Pharmacokinetics and Toxicity |
| - | Review, | Nor, | NA | - | Review, | AD, | NA |
| 7803- | IBC, | Isobavachalcone induces hepatotoxicity in zebrafish embryos and HepG2 cells via the System Xc--GSH-GPX4 signaling pathway in ferroptosis response |
| - | in-vivo, | Nor, | NA | - | in-vitro, | NA, | HepG2 |
| 7766- | ISL, | Isoliquiritigenin alleviates myocardial ischemia-reperfusion injury by regulating the Nrf2/HO-1/SLC7a11/GPX4 axis in mice |
| - | in-vivo, | Stroke, | NA |
| 7765- | ISL, | Isoliquiritigenin as a modulator of the Nrf2 signaling pathway: potential therapeutic implications |
| - | Review, | Var, | NA |
| 7881- | isoO, | Effects of Natural Flavonoid Isoorientin on Growth Performance and Gut Microbiota of Mice |
| - | in-vivo, | Nor, | NA |
| 7878- | isoO, | Cisplatin, | Isoorientin Attenuates Cisplatin-Induced Nephrotoxicity Through the Inhibition of Oxidative Stress and Apoptosis via Activating the SIRT1/SIRT6/Nrf-2 Pathway |
| - | in-vivo, | Nor, | NA |
| 7872- | isoO, | Isoorientin ameliorates H2O2-induced apoptosis and oxidative stress in chondrocytes by regulating MAPK and PI3K/Akt pathways |
| - | in-vivo, | Arthritis, | NA |
| 7871- | isoO, | Cisplatin, | Isoorientin reverses lung cancer drug resistance by promoting ferroptosis via the SIRT6/Nrf2/GPX4 signaling pathway |
| - | vitro+vivo, | Lung, | NA |
| - | vitro+vivo, | AD, | PC12 |
| 7813- | ISQ, | Isoquercitrin Played a Neuroprotective Role in Rats After Cerebral Ischemia/Reperfusion Through Up-Regulating Neuroglobin and Anti-Oxidative Stress |
| - | in-vivo, | Stroke, | NA |
| 8039- | IVM, | Ivermectin-Induced Apoptotic Cell Death in Human SH-SY5Y Cells Involves the Activation of Oxidative Stress and Mitochondrial Pathway and Akt/mTOR-Pathway-Mediated Autophagy |
| - | NA, | neuroblastoma, | SH-SY5Y |
| 7890- | IVT, | Isovitexin protects against cisplatin-induced kidney injury in mice through inhibiting inflammatory and oxidative responses |
| - | in-vivo, | Nor, | NA |
| 7888- | IVT, | Isovitexin Exerts Anti-Inflammatory and Anti-Oxidant Activities on Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting MAPK and NF-κB and Activating HO-1/Nrf2 Pathways |
| - | vitro+vivo, | Nor, | NA |
| 1924- | JG, | Juglone triggers apoptosis of non-small cell lung cancer through the reactive oxygen species -mediated PI3K/Akt pathway |
| - | in-vitro, | Lung, | A549 |
| 1921- | JG, | Juglone induces ferroptotic effect on hepatocellular carcinoma and pan-cancer via the FOSL1-HMOX1 axis |
| - | in-vitro, | PC, | NA | - | vitro+vivo, | PC, | NA |
| 8105- | KAE, | Chemo-preventive and therapeutic effect of the dietary flavonoid kaempferol: A comprehensive review |
| - | Review, | Var, | NA |
| 8069- | KAE, | Kaempferol attenuates cognitive deficit via regulating oxidative stress and neuroinflammation in an ovariectomized rat model of sporadic dementia |
| - | in-vivo, | AD, | NA |
| 8080- | KAE, | Hepatoprotective Effect of Kaempferol—A Review |
| - | Review, | Nor, | NA |
| 8054- | KAE, | Kaempferol Improves Alzheimer's Disease by Inhibiting Neuronal Ferroptosis via Activating GPX4/AKR1C3 Signaling Pathway |
| - | vitro+vivo, | AD, | NA |
| 8055- | KAE, | Molecular Mechanisms of the Anticancer Activity of the Flavonoid Kaempferol: A Comprehensive Review |
| - | Review, | Var, | NA |
| 8245- | LCA, | Licochalcone A Upregulates Nrf2 Antioxidant Pathway and Thereby Alleviates Acetaminophen-Induced Hepatotoxicity |
| - | in-vivo, | LiverDam, | NA |
| 8206- | LCA, | Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways |
| - | in-vivo, | GC, | BGC-823 |
| 8145- | LF, | Neuroprotective Effects of Lactoferrin in Alzheimer's and Parkinson's Diseases: A Narrative Review |
| - | Review, | AD, | NA | - | Review, | Park, | NA |
| 2921- | LT, | Luteolin as a potential hepatoprotective drug: Molecular mechanisms and treatment strategies |
| - | Review, | Nor, | NA |
| 1275- | LT, | Mechanism of luteolin induces ferroptosis in nasopharyngeal carcinoma cells |
| - | in-vitro, | Laryn, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:570 State#:% Dir#:%
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