Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
6090- CHOC,    Cocoa Flavanol Intake and Biomarkers for Cardiometabolic Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- Review, Nor, NA
*Dose↝, *cardioP↑,
6091- CHOC,    Chocolate Consumption in Relation to All-Cause and Cause-Specific Mortality in Women: The Women's Health Initiative
- Study, Nor, NA
*Risk↓, *cardioP↑, *OS↑,
6092- CHOC,    Long-term effect of cocoa extract supplementation on incident hypertension
- Review, Nor, NA
BP↝,
6107- Chol,    Choline supplements: An update
- Review, AD, NA
*memory↑, *cognitive↑, *Dose↝, *BBB↑, *cardioP↑, *ROS↓, *TMAO↑, *memory∅, *eff↑,
6111- Chol,    The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer’s disease
- Human, AD, NA
*Risk↑, *TMAO↑, *Dose↝, *eff↑,
6113- Chol,    Association between choline supplementation and Alzheimer’s disease risk: a systematic review protocol
- Review, AD, NA
*cognitive↑, *eff↑, *Dose↝, *Dose↓,
6112- Chol,    Trimethylamine N-oxide induced cognitive impairment through disruption of blood-brain barrier by inhibiting TGF-β pathway
- in-vivo, AD, NA
*TMAO↑, *cognitive↓, *BBB↝, *TJ↝,
6151- Chol,    Effect of Choline Alphoscerate on the Survival of Glioblastoma Patients: A Retrospective, Single-Center Study
- Study, GBM, NA
OS↑,
6150- Chol,    Effects of choline alfoscerate on cognitive function and quality of life in type 2 diabetes: A double-blind, randomized, placebo-controlled trial
- Trial, AD, NA
*cognitive↑,
6108- Chol,    Trimethylamine-N-Oxide (TMAO) as a Rising-Star Metabolite: Implications for Human Health
- Review, Nor, NA - Review, AD, NA
*TMAO↑, *ROS↑, *NADPH↑, *Ca+2↑, *AntiAg↓, *cognitive↓, *TJ↓, *CLDN1↓, *ZO-1↓, *Inflam↑, *NLRP3↑, *ER Stress↑, *cognitive↓, *Dose↝, *eff↑, *other↝, *other↝, *other↝,
6121- Chol,    Dietary Choline Supplements, but Not Eggs, Raise Fasting TMAO Levels in Participants with Normal Renal Function: A Randomized Clinical Trial
- Human, AD, NA
*TMAO⇅, *eff↑,
6114- Chol,    Dietary Choline Intake and Risk of Alzheimer's Dementia in Older Adults
- Study, AD, NA
*Risk↓, *Dose↝,
6115- Chol,    Association of dietary choline intake with incidence of dementia, Alzheimer disease, and mild cognitive impairment: a large population-based prospective cohort study
- Study, AD, NA
*Risk↓, *cognitive↑, *Dose↝, *TMAO↑,
6116- Chol,    Is dietary choline intake related to dementia and Alzheimer’s disease risks? Results from the Framingham Heart Study
- Study, AD, NA
*Risk↓, *TMAO↑,
6117- Chol,    Citicoline and Memory Function in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
- Trial, AD, NA
*memory↑, *TMAO∅, *Dose↝,
6118- Chol,    Comparison of the effects of choline alphoscerate and citicoline in patients with dementia disorders: a systematic review and meta-analysis
- Review, NA, NA
*eff↑, *cognitive↑, *BBB↑, *Ach↑,
6119- Chol,    Is Citicoline Effective in Preventing and Slowing Down Dementia?—A Systematic Review and a Meta-Analysis
- Review, AD, NA - Review, Stroke, NA
*cognitive↑, *Ach↑, *Apoptosis↓, *neuroP↑, *memory↑,
6120- Chol,    Citicoline: A Cholinergic Precursor with a Pivotal Role in Dementia and Alzheimer’s Disease
- Trial, AD, NA
*Dose↝, *cognitive↑, *QoL?,
6106- Chol,    Serum choline is associated with hepatocellular carcinoma survival: a prospective cohort study
- Study, HCC, NA
OS↑,
6105- Chol,    Choline supplementation protects against liver damage by normalizing cholesterol metabolism in Pemt/Ldlr knockout mice fed a high-fat diet
- in-vivo, Nor, NA
*hepatoP↑,
6104- Chol,    Dietary choline intake and colorectal cancer: a cross-sectional study of 2005–2018 NHANES cycles
- Study, HCC, NA
Risk∅, Risk⇅,
6103- Chol,    Dietary Choline Supplementation Attenuates High-Fat-Diet-Induced Hepatocellular Carcinoma in Mice
- in-vivo, HCC, NA
AntiTum↑, eff↑,
6102- Chol,    Higher dietary choline intake is associated with increased risk of all-cause and cause-specific mortality: A systematic review and dose-response meta-analysis of cohort studies
- Analysis, CardioV, NA
*Risk↑,
6101- Chol,    Effect of Choline Forms and Gut Microbiota Composition on Trimethylamine-N-Oxide Response in Healthy Men
- Human, Nor, NA
*TMAO↑, *Dose↝, *GutMicro↝, *TMAO∅,
6100- Chol,    Phosphatidylcholine-Derived Lipid Mediators: The Crosstalk Between Cancer Cells and Immune Cells
- Review, Var, NA
other↑, other↝, other↝, other↝, other↝,
6099- Chol,    Choline metabolism-based molecular diagnosis of cancer: an update
- Review, Var, NA
other↝, other↝,
6098- Chol,    Choline
- Review, Nor, NA - Review, AD, NA
*BioAv↝, *Dose↝, *cardioP↑, *BP↓, *cognitive↑, *memory↑, eff∅,
6097- Chol,    Choline intake and risk of lethal prostate cancer: incidence and survival
- Study, Pca, NA
Risk↑, other↝,
6096- Chol,    Plasma methionine, choline, betaine, and dimethylglycine in relation to colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)
- Study, CRC, NA
Risk↓, other↑,
6095- Chol,    Choline metabolism and its implications in cancer
- Review, Var, NA
BioAv↑, other↑, other↑, other↝,
6149- Chol,    Prostate cancer progression and mortality: a review of diet and lifestyle factors
- Review, Var, NA
Risk↑,
3699- Chol,    Association of dietary cholesterol and egg intakes with the risk of incident dementia or Alzheimer disease: the Kuopio Ischaemic Heart Disease Risk Factor Study
- Study, AD, NA
*other∅, *cognitive↑,
3700- Chol,    Eggs and Health Special Issue
- Review, Nor, NA
*other↑, *other↑, *Inflam↓, *ROS↓, *antiOx↑, *Iron↑, *cardioP∅,
3701- Chol,    Lifelong choline supplementation ameliorates Alzheimer's disease pathology and associated cognitive deficits by attenuating microglia activation
- in-vivo, AD, NA
*Ach↑, *Aβ↓, *memory↑, *APP↓, *eff↑, *neuroP↑, *Dose↑,
3702- Chol,    Alzheimer's Disease: Targeting the Cholinergic System
- NA, AD, NA
*memory↑, *Sleep↑, *Ach↑,
3703- Chol,    Alzheimer's disease. Correlation of cortical choline acetyltransferase activity with the severity of dementia and histological abnormalities
- Human, AD, NA
*ChAT↑,
3704- Chol,    Acetylcholine, aging, and Alzheimer's disease
- Review, AD, NA
*memory↑, *eff↑, *eff↑,
3705- Chol,  LEC,    Effects of consumption of choline and lecithin on neurological and cardiovascular systems
- Review, AD, NA
*memory↑, *cognitive↑,
4262- Chol,    Choline up-regulates BDNF and down-regulates TrkB neurotrophin receptor in rat cortical cell culture
- in-vitro, NA, NA
*TrkB↑, *BDNF↑,
4261- Chol,  VitB12,  FA,  VitB2,    B-Vitamin and Choline Supplementation Changes the Ischemic Brain
- Study, Stroke, NA
*BDNF↑, *Hcy/homoC↓,
8180- Chol,    Unlocking choline's potential in Alzheimer's disease: A narrative review exploring the neuroprotective and neurotrophic role of phosphatidylcholine and assessing its impact on memory and learning
- Review, AD, NA
Aβ↓, cognitive↑,
6133- CHr,    Chrysin in PI3K/AKT and other apoptosis signalling pathways, and its effect on HeLa cells.
- Review, Var, NA
TumCP↓, Apoptosis↑, angioG↓, eff↑, CYP19↓, Hif1a↓, VEGF↓, NF-kB↓, PI3K↓, Akt↓,
6132- CHr,  MET,    Synergistic Growth Inhibitory Effects of Chrysin and Metformin Combination on Breast Cancer Cells through hTERT and Cyclin D1 Suppression
- in-vitro, BC, T47D
eff↑, cycD1/CCND1↓, hTERT/TERT↓, TumCP↓, Apoptosis↑, TumCI↓, TumMeta↓, angioG↓, selectivity↑,
6130- CHr,    Anticancer Properties of Chrysin on Colon Cancer Cells, In vitro and In vivo with Modulation of Caspase-3, -9, Bax and Sall4
- vitro+vivo, Colon, CT26
tumCV↓, Apoptosis↑, TumVol↓, BAX↑, SALL4↓, Casp3↑, Casp9↑, ChemoSen↑, GSH↓,
6131- CHr,  Bor,  Z,    Fabrication of phenyl boronic acid modified pH-responsive zinc oxide nanoparticles as targeted delivery of chrysin on human A549 cells
- in-vitro, Lung, A549
*BioAv↑, ROS↑, TumCD↑, TumCCA↑, MMP2↓, TumMeta↓, TumCI↓, GSH↓, eff↑,
6139- CHr,    Chrysin and its nanoformulations in cancer therapy: A systematic review of their radiosensitizing, phototherapy-enhancing potentials
- Review, Var, NA
RadioS↑, PhotoS↑, ROS↑, DNAdam↑, TumCCA↑, TumCD↑, selectivity↑, *ROS↓, *Inflam↓, *DNAdam↓, *antiOx↑, *lipid-P↓, *BioAv↑, eff↑, GSH↓, Catalase↓, ALAT↓, Ca+2↓, MDA↑,
6134- CHr,  QC,  RT,    Comparative Pharmacokinetics and Safety of a Micellar Chrysin–Quercetin–Rutin Formulation: A Randomized Crossover Trial
- Trial, Nor, NA
Dose↝, BioAv↑, MPT↑, eff↑, Half-Life↑,
6135- CHr,    Chrysin as a Multifunctional Therapeutic Flavonoid: Emerging Insights in Pathogenesis Management: A Narrative Review
- Review, Var, NA - Review, AD, NA
Inflam↓, angioG↓, Apoptosis↑, TumAuto↑, TumCCA↑, BioAv↓, Half-Life↓, BioAv↓, *ROS↓, *hepatoP↑, *RenoP↑, TET1↑, MMP9↓, cMyc↓, Ki-67↓, CBR1↓, ROS↑, ChemoSen↑, Bax:Bcl2↑, PUMA↑, NOTCH1↑, *AntiDiabetic↑, *neuroP↑, *GABA↑, *DNAdam↓, *BDNF↑, *memory↑, *AGEs↓, *Aβ↓, *cardioP↑, *AntiArt↑, eff↑, eff↑, *eff↑, RadioS↑, eff↑, ChemoSen↑, eff↑,
6136- CHr,  Tras,    Synergistic anticancer effects of Chrysin and trastuzumab in HER2-Positive breast cancer cells
- in-vitro, BC, SkBr3 - in-vitro, BC, BT474 - in-vitro, Nor, MCF10
eff↑, HER2/EBBR2↓, p‑STAT3↓, PD-L1↓, ChemoSen↑,
6137- CHr,    Effects of Chrysin and Its Major Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide on Cytochrome P450 Enzymes and on OATP, P-gp, BCRP, and MRP2 Transporters
- in-vitro, NA, NA
CYP2C9↓, OATPs↓, ABCG2↓, BioEnh↝,

Showing Research Papers: 2301 to 2350 of 8269
Prev Page 47 of 166 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 8269

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0)

CBR1↓, 1,   SALL4↓, 1,  

Redox & Oxidative Stress(tgid=1)

Catalase↓, 1,   GSH↓, 3,   MDA↑, 1,   ROS↑, 3,  

Mitochondria & Bioenergetics(tgid=3)

MPT↑, 1,  

Core Metabolism/Glycolysis(tgid=4)

ALAT↓, 1,   cMyc↓, 1,  

Cell Death(tgid=5)

Akt↓, 1,   Apoptosis↑, 4,   BAX↑, 1,   Bax:Bcl2↑, 1,   Casp3↑, 1,   Casp9↑, 1,   hTERT/TERT↓, 1,   PUMA↑, 1,   TumCD↑, 2,  

Kinase & Signal Transduction(tgid=6)

HER2/EBBR2↓, 1,  

Transcription & Epigenetics(tgid=7)

other↑, 4,   other↝, 8,   PhotoS↑, 1,   tumCV↓, 1,  

Autophagy & Lysosomes(tgid=9)

TumAuto↑, 1,  

DNA Damage & Repair(tgid=10)

DNAdam↑, 1,  

Cell Cycle & Senescence(tgid=11)

cycD1/CCND1↓, 1,   TumCCA↑, 3,  

Proliferation, Differentiation & Cell State(tgid=12)

NOTCH1↑, 1,   PI3K↓, 1,   p‑STAT3↓, 1,  

Migration(tgid=13)

Ca+2↓, 1,   Ki-67↓, 1,   MMP2↓, 1,   MMP9↓, 1,   TET1↑, 1,   TumCI↓, 2,   TumCP↓, 2,   TumMeta↓, 2,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 3,   Hif1a↓, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15)

OATPs↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

Inflam↓, 1,   NF-kB↓, 1,   PD-L1↓, 1,  

Protein Aggregation(tgid=19)

Aβ↓, 1,  

Hormonal & Nuclear Receptors(tgid=20)

CYP19↓, 1,  

Drug Metabolism & Resistance(tgid=21)

ABCG2↓, 1,   BioAv↓, 2,   BioAv↑, 2,   BioEnh↝, 1,   ChemoSen↑, 4,   CYP2C9↓, 1,   Dose↝, 1,   eff↑, 11,   eff∅, 1,   Half-Life↓, 1,   Half-Life↑, 1,   RadioS↑, 2,   selectivity↑, 2,  

Clinical Biomarkers(tgid=22)

ALAT↓, 1,   BP↝, 1,   HER2/EBBR2↓, 1,   hTERT/TERT↓, 1,   Ki-67↓, 1,   PD-L1↓, 1,  

Functional Outcomes(tgid=23)

AntiTum↑, 1,   cognitive↑, 1,   OS↑, 2,   Risk↓, 1,   Risk↑, 2,   Risk⇅, 1,   Risk∅, 1,   TumVol↓, 1,  
Total Targets: 74

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0)

AntiArt↑, 1,   TMAO↑, 7,   TMAO⇅, 1,   TMAO∅, 2,  

Redox & Oxidative Stress(tgid=1)

antiOx↑, 2,   Iron↑, 1,   lipid-P↓, 1,   ROS↓, 4,   ROS↑, 1,  

Core Metabolism/Glycolysis(tgid=4)

NADPH↑, 1,  

Cell Death(tgid=5)

Apoptosis↓, 1,  

Transcription & Epigenetics(tgid=7)

Ach↑, 4,   other↑, 2,   other↝, 3,   other∅, 1,  

Protein Folding & ER Stress(tgid=8)

ER Stress↑, 1,  

DNA Damage & Repair(tgid=10)

DNAdam↓, 2,  

Migration(tgid=13)

AntiAg↓, 1,   APP↓, 1,   Ca+2↑, 1,   CLDN1↓, 1,   TJ↓, 1,   TJ↝, 1,   ZO-1↓, 1,  

Barriers & Transport(tgid=15)

BBB↑, 2,   BBB↝, 1,  

Immune & Inflammatory Signaling(tgid=16)

Inflam↓, 2,   Inflam↑, 1,  

Synaptic & Neurotransmission(tgid=18)

BDNF↑, 3,   ChAT↑, 1,   GABA↑, 1,   TrkB↑, 1,  

Protein Aggregation(tgid=19)

AGEs↓, 1,   Aβ↓, 2,   NLRP3↑, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↑, 2,   BioAv↝, 1,   Dose↓, 1,   Dose↑, 1,   Dose↝, 11,   eff↑, 10,  

Clinical Biomarkers(tgid=22)

BP↓, 1,   GutMicro↝, 1,   Hcy/homoC↓, 1,  

Functional Outcomes(tgid=23)

AntiDiabetic↑, 1,   cardioP↑, 5,   cardioP∅, 1,   cognitive↓, 3,   cognitive↑, 10,   hepatoP↑, 2,   memory↑, 9,   memory∅, 1,   neuroP↑, 3,   OS↑, 1,   QoL?, 1,   RenoP↑, 1,   Risk↓, 4,   Risk↑, 2,   Sleep↑, 1,  
Total Targets: 59

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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