| Source: |
| Type: |
| Drug dosage vs efficacy, and actual dosage number of research papers. |
| 5908- | CAR, | Carvacrol improves neurological function by inhibiting TRPM7-mediated BBB disruption and hemorrhage after TBI |
| - | in-vivo, | Nor, | NA |
| 5910- | CAR, | Oregano Phytocomplex Induces Programmed Cell Death in Melanoma Lines via Mitochondria and DNA Damage |
| - | in-vitro, | Melanoma, | B16-F10 | - | NA, | NA, | A375 |
| 5894- | CAR, | Targeting Gastrointestinal Cancers with Carvacrol: Mechanistic Insights and Therapeutic Potential |
| - | Review, | Var, | NA |
| 5892- | CAR, | SRF, | Carvacrol potentiates immunity and sorafenib anti-cancer efficacy by targeting HIF-1α/STAT3/ FGL1 pathway: in silico and in vivo study |
| - | in-vivo, | HCC, | NA |
| 5891- | CAR, | SRF, | Carvacrol enhances anti-tumor activity and mitigates cardiotoxicity of sorafenib in thioacetamide-induced hepatocellular carcinoma model through inhibiting TRPM7 |
| - | in-vivo, | HCC, | NA |
| 5889- | CAR, | Effect of carvacrol on pulmonary function tests, and total and differential white blood cell counts in healthy volunteers: A randomized clinical trial |
| - | Trial, | Nor, | NA |
| 5929- | Catechins, | Phase I trial of oral green tea extract in adult patients with solid tumors |
| - | Trial, | Var, | NA |
| 5916- | Cats, | Chemo, | Uncaria tomentosa—Adjuvant Treatment for Breast Cancer: Clinical Trial |
| - | Trial, | BC, | NA |
| 5917- | Cats, | Uncaria tomentosa for Reducing Side Effects Caused by Chemotherapy in CRC Patients: Clinical Trial |
| - | Trial, | CRC, | NA |
| 5918- | Cats, | Uncaria tomentosa (cat's claw) improves quality of life in patients with advanced solid tumors |
| - | Trial, | Var, | NA |
| 6253- | CBC/D, | The SHH/GLI signaling pathway: a therapeutic target for medulloblastoma |
| - | Review, | MB, | NA |
| 5813- | CBD, | Pharmacokinetics of Cannabidiol: A Systematic Review and Meta-Regression Analysis |
| - | Review, | Var, | NA |
| 5960- | CEL, | Phase II, Randomized, Placebo-Controlled Trial of Neoadjuvant Celecoxib in Men With Clinically Localized Prostate Cancer: Evaluation of Drug-Specific Biomarkers |
| - | Trial, | Pca, | NA |
| 5959- | CEL, | Celecoxib induces apoptosis in cervical cancer cells independent of cyclooxygenase using NF-κB as a possible target |
| - | in-vitro, | Cerv, | HeLa |
| 5953- | Cela, | CUR, | The Combination of Celastrol and Curcumin Enhances the Antitumor Effect in Nasopharyngeal Carcinoma by Inducing Ferroptosis |
| - | vitro+vivo, | NPC, | NA |
| 5940- | Cela, | Celastrol Suppresses Angiogenesis-Mediated Tumor Growth through Inhibition of AKT/Mammalian Target of Rapamycin Pathway |
| - | in-vivo, | Pca, | PC3 |
| 5952- | Cela, | Celastrol attenuates Alzheimer’s disease-mediated learning and memory impairment by inhibiting endoplasmic reticulum stress-induced inflammation and oxidative stress |
| - | in-vivo, | AD, | NA |
| 5943- | Cela, | Celastrol: A Spectrum of Treatment Opportunities in Chronic Diseases |
| - | Review, | Arthritis, | NA | - | Review, | IBD, | NA | - | Review, | AD, | NA | - | Review, | Park, | NA |
| 6615- | Cen, | Asiaticoside suppresses cell proliferation by inhibiting the NF-κB signaling pathway in colorectal cancer |
| - | vitro+vivo, | CRC, | HCT116 | - | in-vitro, | CRC, | SW480 | - | in-vitro, | CRC, | LoVo |
| 6636- | Cen, | Pharmacokinetics and Pharmacodynamics of Key Components of a Standardized Centella asiatica Product in Cognitively Impaired Older Adults: A Phase 1, Double-Blind, Randomized Clinical Trial |
| - | Trial, | AD, | NA |
| 6637- | Cen, | Effects of Centella asiatica (L.) Urb. on cognitive function and mood related outcomes: A Systematic Review and Meta-analysis |
| - | Review, | AD, | NA |
| 6659- | Cen, | Effect of Centella asiatica on mild cognitive impairment (MCI) and other common age-related clinical problems |
| - | Trial, | AD, | NA |
| 6657- | Cen, | Safety and Target Engagement of Centella Asiatica in Cognitive Impairment |
| - | Trial, | AD, | NA |
| 6655- | Cen, | Centella asiatica improves cognitive function and alters the hippocampal metabolome of aged Tg2576 and wild-type mice |
| - | in-vivo, | AD, | NA |
| 6648- | Cen, | Centella asiatica (L.) Urban: From Traditional Medicine to Modern Medicine with Neuroprotective Potential |
| - | Review, | AD, | NA |
| 5970- | CET, | Cetuximab |
| - | Review, | CRC, | NA | - | Review, | HNSCC, | NA |
| 5967- | CET, | FDA grants accelerated approval to adagrasib with cetuximab for KRAS G12C-mutated colorectal cancer |
| - | Study, | CRC, | NA |
| 6022- | CGA, | Chlorogenic Acid: Recent Advances on Its Dual Role as a Food Additive and a Nutraceutical against Metabolic Syndrome |
| - | Review, | Nor, | NA |
| 6019- | CGA, | immuno, | Combination immunotherapy of chlorogenic acid liposomes modified with sialic acid and PD-1 blockers effectively enhances the anti-tumor immune response and therapeutic effects |
| - | in-vivo, | Melanoma, | NA |
| 6037- | CGA, | Pharmacokinetics and brain penetration study of chlorogenic acid in rats |
| - | in-vivo, | AD, | NA | - | in-vivo, | Stroke, | NA |
| 6040- | CGA, | Protective effect of chlorogenic acid on cognitive impairment in rats with early Alzheimer's disease via Wnt signaling pathway |
| - | in-vivo, | AD, | NA |
| 6041- | CGA, | Effect of Chlorogenic Acid Intake on Cognitive Function in the Elderly: A Pilot Study |
| - | Trial, | AD, | NA |
| 6043- | CGA, | SeNPs, | Enhanced Effect of Combining Chlorogenic Acid on Selenium Nanoparticles in Inhibiting Amyloid β Aggregation and Reactive Oxygen Species Formation In Vitro |
| - | in-vitro, | AD, | NA |
| 6035- | CGA, | Effect of Chlorogenic Acids on Cognitive Function in Mild Cognitive Impairment: A Randomized Controlled Crossover Trial |
| - | Trial, | Nor, | NA |
| 6029- | CGA, | Pharmacokinetics of chlorogenic acids absorbed in human plasma and their metabolites following oral ingestion of coffee drink |
| - | Trial, | Nor, | NA |
| 6028- | CGA, | Chlorogenic acids from green coffee extract are highly bioavailable in humans |
| - | Trial, | Nor, | NA |
| 7185- | CHA, | Chaetocin-induced ROS-mediated apoptosis involves ATM–YAP1 axis and JNK-dependent inhibition of glucose metabolism |
| - | vitro+vivo, | GBM, | A172 | - | in-vitro, | GBM, | T98G | - | in-vitro, | GBM, | U87MG |
| 7163- | CHA, | The anticancer effects of chaetocin are independent of programmed cell death and hypoxia, and are associated with inhibition of endothelial cell proliferation |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | OS, | U2OS | - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | HeLa | - | in-vivo, | Ovarian, | SKOV3 |
| 7161- | CHA, | Chaetocin is a nonspecific inhibitor of histone lysine methyltransferases |
| - | Review, | Var, | NA |
| 6001- | Chit, | Recent advances in engineering chitosan-based nanoplatforms in biotherapeutic multi-delivery for multi-targeted disease treatments: Promises and outlooks |
| - | Review, | Var, | HepG2 | - | Review, | AD, | NA |
| 6071- | CHL, | First-in-human clinical trial of high-dose sodium copper chlorophyllin: Pharmacology and efficacy as a dual immunomodulatory/antiviral agent |
| - | Trial, | Nor, | NA |
| 6083- | CHOC, | Preventive Effects of Cocoa and Cocoa Antioxidants in Colon Cancer |
| - | Review, | Colon, | NA |
| 6087- | CHOC, | Effect of cocoa flavanol supplementation for the prevention of cardiovascular disease events: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial |
| - | Trial, | Nor, | NA |
| - | Trial, | Nor, | NA |
| 6090- | CHOC, | Cocoa Flavanol Intake and Biomarkers for Cardiometabolic Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials |
| - | Review, | Nor, | NA |
| 6107- | Chol, | Choline supplements: An update |
| - | Review, | AD, | NA |
| 6111- | Chol, | The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer’s disease |
| - | Human, | AD, | NA |
| 6113- | Chol, | Association between choline supplementation and Alzheimer’s disease risk: a systematic review protocol |
| - | Review, | AD, | NA |
| 6108- | Chol, | Trimethylamine-N-Oxide (TMAO) as a Rising-Star Metabolite: Implications for Human Health |
| - | Review, | Nor, | NA | - | Review, | AD, | NA |
| 6114- | Chol, | Dietary Choline Intake and Risk of Alzheimer's Dementia in Older Adults |
| - | Study, | AD, | NA |
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:1114 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid