Cancer Research Results

, aggregation: Click to Expand ⟱
Source:
Type:
Beta-Amyloid (): In Alzheimer’s disease, peptides tend to misfold and aggregate into oligomers and fibrils.


Scientific Papers found: Click to Expand⟱
3898- MCT,    Potential of coconut oil and medium chain triglycerides in the prevention and treatment of Alzheimer's disease
- Review, AD, NA
*neuroP↑, *cognitive↑, *↓, *Inflam↓, *ROS↓,
4106- MF,    Cognitive Decline: Current Intervention Strategies and Integrative Therapeutic Approaches for Alzheimer's Disease
- Review, AD, NA
*cognitive↑, *memory↑, *↓, *neuroP↑,
4118- MF,    Effects of transcranial magnetic stimulation on neurobiological changes in Alzheimer's disease
- Review, AD, NA
*cognitive↑, *BDNF↑, *neuroP↑, *memory↑, *ROS↓, *antiOx↑, *↓, *eff↑,
4119- MF,    Therapeutic potential and mechanisms of repetitive transcranial magnetic stimulation in Alzheimer’s disease: a literature review
- Review, AD, NA
*cognitive↑, *memory↑, *motorD↑, *eff↑, *eff↑, *Dose↝, *Dose↝, *Dose↝, *BDNF↑, *↓, *eff↑,
3735- MF,    Examining the effects of extremely low-frequency magnetic fields on cognitive functions and functional brain markers in aged mice
- in-vivo, AD, NA
*APP∅, *∅, *Inflam∅, *memory∅,
3740- MF,    Gamma rhythm low field magnetic stimulation alleviates neuropathologic changes and rescues memory and cognitive impairments in a mouse model of Alzheimer's disease
- in-vivo, AD, NA
*cognitive↑, *Dose↝, *↓, *PSD95↑,
3739- MF,    Early intervention using long-term rhythmic pulsed magnetic stimulation alleviates cognitive decline in a 5xFAD mouse model of Alzheimer's disease
- in-vivo, AD, NA
*memory↑, *cognitive↑, *↓, *FGF↑,
3725- MF,    Short-term effects of extremely low frequency electromagnetic fields exposure on Alzheimer's disease in rats
- in-vivo, AD, NA
*Weight∅, *memory∅, *cognitive∅, *∅,
212- MFrot,  MF,    Rotating magnetic field inhibits protein aggregation and alleviates cognitive impairment in Alzheimer’s disease mice
- in-vivo, AD, SH-SY5Y
*β-Amyloid↓, *cognitive↑, *motorD↑, *ROS↓, *memory↑, *?,
204- MFrot,  MF,    Rotating magnetic field improved cognitive and memory impairments in a sporadic ad model of mice by regulating microglial polarization
- in-vivo, AD, NA
*NF-kB↓, *MAPK↓, *TLR4↓, *memory↑, *cognitive↑, *TGF-β1↑, *ARG1/2↑, *IL4↑, *IL10↑, *IL6↓, *IL1↓, *TNF-α↓, *iNOS↓, *ROS↓, *NO↓, *MyD88↓, *p‑IKKα↓, *p‑IκB↓, *p‑p65↓, *p‑JNK↓, *p‑p38↓, *ERK↓, *neuroP↑, *↓,
3488- MFrot,  MF,    Rotating magnetic field improves cognitive and memory impairments in APP/PS1 mice by activating autophagy and inhibiting the PI3K/AKT/mTOR signaling pathway
- in-vivo, AD, NA
*cognitive↑, *memory↑, *neuroP↑, *↓, *PI3K↓, *Akt↓, *mTOR↓,
3489- MFrot,  MF,    Rotating magnetic field inhibits protein aggregation and alleviates cognitive impairment in Alzheimer's disease mice.
- in-vivo, AD, NA
*↓, *motorD↑, *cognitive↑, *memory↑, *ROS↓,
3745- MFrot,  MF,    The neurobiological foundation of effective repetitive transcranial magnetic brain stimulation in Alzheimer's disease
- Review, AD, NA
*neuroP↑, *ROS↓, *Inflam↓, *5HT↑, *cFos↑, *↓, *memory↑, *BDNF↑, *Ach↑, *AChE↓, *cognitive↑, *BDNF↑, *NGF↑, *β-catenin/ZEB1↑, *p‑Akt↓, *mTOR↓, *MMP1↓, *MMP9↓, *MMP-10↓, *TIMP1↑, *TIMP2↑,
3834- Moringa,    Moringa Oleifera Alleviates Homocysteine-Induced Alzheimer's Disease-Like Pathology and Cognitive Impairments
- in-vivo, AD, NA
*antiOx↑, *Inflam↓, *neuroP↑, *↓, *BACE/β-secretase↓, *cal2↓, *p‑tau↓, *ROS↓, *SOD↑, *MDA↓, *cognitive↑, *memory↑,
3835- Moringa,    Moringa Oleifera Alleviates Burden and Improves Synaptic Plasticity and Cognitive Impairments in APP/PS1 Mice
- in-vivo, AD, NA
*antiOx↑, *Inflam↓, *AChE↓, *neuroP↑, *Mood↑, *cognitive↑, *memory↑, *↓, *BACE/β-secretase↓, *AEP↓, *IDE↑, *NEP↑, *LRP1↑, *PSD95↑, *STEP↓, *APP↓,
3848- MSM,    Modulatory effect of methylsulfonylmethane against BPA/γ-radiation induced neurodegenerative alterations in rats: Influence of TREM-2/DAP-12/Syk pathway
- in-vitro, AD, NA
*ROS↓, *Inflam↓, *neuroP↑, *ER(estro)↑, *NRF2↑, *HO-1↑, *Trx1↑, *TXNIP↓, *MDA↓, *NOX↓, *GSH↑, *GPx↑, *SOD↑, *Catalase↑, *BDNF↑, *AChE↓, *p‑tau↓, *↓,
3810- mushLions,    Key Mechanisms and Potential Implications of Hericium erinaceus in NLRP3 Inflammasome Activation by Reactive Oxygen Species during Alzheimer’s Disease
- Review, NA, NA
*neuroP↑, *p‑tau↓, *APP↓, *↓, *ROS↓, *Inflam↓, *NLRP3↓,
3814- mushLions,    Lion's Mane (Hericium erinaceus) Exerts Anxiolytic Effects in the rTg4510 Tau Mouse Model
- in-vitro, AD, NA
*neuroP↑, *cognitive↑, *cognitive∅, *BBB↑, *NGF↑, *BDNF↑, *NO↓, *memory↑, *↓,
3813- mushLions,    Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer's disease-related pathologies in APPswe/PS1dE9 transgenic mice
- in-vitro, AD, NA
*↓, *cognitive↑, *neuroP↑,
3812- mushLions,    Structural characterization of polysaccharide purified from Hericium erinaceus fermented mycelium and its pharmacological basis for application in Alzheimer's disease: Oxidative stress related calcium homeostasis
- in-vitro, AD, NA
*cognitive↑, *↓, *p‑tau↓, *ROS↓, *NRF2↓, *Ca+2↝,
3809- mushLions,    The Monkey Head Mushroom and Memory Enhancement in Alzheimer's Disease
- Review, NA, NA
*cognitive↑, *Apoptosis↓, *↓, *AChE↓, *BACE/β-secretase↓,
7828- Myr,  MBS,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*BBB↑, *neuroP↑, *cognitive↑, *↓, *ADAM10↑, *BACE/β-secretase↝, *IronCh↑, *Iron↓, *AChE↓, *ROS↓,
6486- Nimb,    Nimbolide: promising agent for prevention and treatment of chronic diseases
- Review, Var, NA - Review, AD, NA
*other↝, *Inflam↓, AntiCan↑, *Bacteria↓, *AntiViral↑, *neuroP↑, *hepatoP↑, *ROS?, *NRF2↑, *HO-1↑, *TLR4↓, *NF-kB↓, *AChE↓, *↓, *GSK‐3β↓, *LDL↓, *DNAdam↓, *lipid-P↓, *antiOx↑, *SOD1↑, *GSH↑, *IL6↓, *IL1β↓, *STAT3↓, *GPx↑, *Catalase↑, *MDA↓, *AntiDiabetic↑, *HDL↓, *MCP1/CCL2↓, *VEGF↓, *MMP9↓, *GutMicro↑, TumCP↓, TumCCA↑, TumCMig↓, NF-kB↓, ROS↑, PI3K↓, Akt↓, mTOR↓, ERK↓, EMT↓, TumMeta↓, ChemoSen↑, eff↑, selectivity↑, CDK4↓, CDK6↓, Wnt↓, β-catenin/ZEB1↓, STAT3↓, MMP2↓, Sp1/3/4↓, AP-1↓, P21↑, *AntiArt↑, *IL23↓, *IL17↓, *IFN-γ↓, *HSP70/HSPA5↓,
7831- PCA,  MBS,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*BBB↑, *neuroP↑, *↓, *p‑tau↓, *autophagy↓, *GSK‐3β↓, *NeuroI↓, *iNOS↓, *COX2/PTGS2↓, *BDNF↑, *MEF2D↑, *cognitive↑, *memory↑,
3598- PI,    Piperine attenuates cognitive impairment in an experimental mouse model of sporadic Alzheimer's disease
- in-vivo, AD, NA
*ROS↓, *Inflam↓, *cognitive↑, *↓, *tau↓,
2963- PL,    Piperlongumine activates Sirtuin1 and improves cognitive function in a murine model of Alzheimer’s disease
- in-vitro, AD, HEK293
*SIRT1↑, *cognitive↑, *↓, *Inflam↓, *neuroP↑, memory↑, Dose↓, NAD↑,
3605- QC,    Protective effect of quercetin in primary neurons against (1–42): relevance to Alzheimer's disease
- Review, AD, NA
*↓, *ROS↓, *lipid-P↓, *Apoptosis↓,
3380- QC,    Quercetin as a JAK–STAT inhibitor: a potential role in solid tumors and neurodegenerative diseases
- Review, Var, NA - Review, Park, NA - Review, AD, NA
JAK↓, STAT↓, Inflam↓, NO↓, COX2/PTGS2↓, CRP↓, selectivity↑, *neuroP↑, STAT3↓, cycD1/CCND1↓, MMP2↓, STAT4↓, JAK2↓, TumCP↓, Diff↓, *eff↑, *IL6↓, *TNF-α↓, *IL1β↓, *↓,
3343- QC,    Quercetin, a Flavonoid with Great Pharmacological Capacity
- Review, Var, NA - Review, AD, NA - Review, Arthritis, NA
*antiOx↑, *ROS↓, *angioG↓, *Inflam↓, *BioAv↓, *Half-Life↑, *GSH↑, *SOD↑, *Catalase↑, *Nrf1↑, *BP↓, *cardioP↑, *IL10↓, *TNF-α↓, *↓, *GSK‐3β↓, *tau↓, *neuroP↑, *Pain↓, *COX2/PTGS2↓, *NRF2↑, *HO-1↑, *IL1β↓, *IL17↓, *MCP1/CCL2↓, PKCδ↓, ERK↓, BAX↓, cMyc↓, KRAS↓, ROS↓, selectivity↑, tumCV↓, Apoptosis↑, TumCCA↑, eff↑, P-gp/ABCB1↓, eff↑, eff↑, eff↑, eff↑, CycB/CCNB1↓, CDK1↓, CDK4↓, CDK2↓, TOP2↓, Cyt‑c↑, cl‑PARP↑, MMP↓, HSP70/HSPA5↓, HSP90↓, MDM2↓, RAS↓, eff↑,
3336- QC,    Neuroprotective Effects of Quercetin in Alzheimer’s Disease
- Review, AD, NA
*neuroP↑, *lipid-P↓, *antiOx↑, *↓, *Inflam↓, *BBB↝, *NF-kB↓, *iNOS↓, *memory↑, *cognitive↑, *AChE↓, *MMP↑, *ROS↓, *ATP↑, *AMPK↑, *NADPH↓, *p‑tau↓,
3374- QC,    Therapeutic effects of quercetin in oral cancer therapy: a systematic review of preclinical evidence focused on oxidative damage, apoptosis and anti-metastasis
- Review, Oral, NA - Review, AD, NA
α-SMA↓, α-SMA↑, TumCP↓, tumCV↓, TumVol↓, TumCI↓, TumMeta↓, TumCMig↓, ROS↑, Apoptosis↑, BioAv↓, *neuroP↑, *antiOx↑, *Inflam↓, *↓, *cardioP↑, MMP↓, Cyt‑c↑, MMP2↓, MMP9↓, EMT↓, MMPs↓, Twist↓, Slug↓, Ca+2↑, AIF↑, Endon↑, P-gp/ABCB1↓, LDH↑, HK2↓, PKA↓, Glycolysis↓, GlucoseCon↓, lactateProd↓, GRP78/BiP↑, Casp12↑, CHOP/DDIT3↑,
3604- QC,    Quercetin enrich diet during the early-middle not middle-late stage of alzheimer’s disease ameliorates cognitive dysfunction
- in-vivo, AD, NA
*cognitive↑, *↓, *neuroP↑, *BACE/β-secretase↓, *p‑SMAD2↓, *p‑STAT3↓, *SPARC↓,
6056- RES,  SeNPs,    A comparative study of resveratrol and resveratrol-functional selenium nanoparticles: Inhibiting amyloid β aggregation and reactive oxygen species formation properties
- Study, AD, NA
*antiOx↑, *eff↑, *ROS↓, *Apoptosis↓, *↓,
6051- RES,  SeNPs,  Chit,    Resveratrol-loaded selenium/chitosan nano-flowers alleviate glucolipid metabolism disorder-associated cognitive impairment in Alzheimer's disease
- in-vivo, AD, NA
*Inflam↓, *ROS↓, *GutMicro↑, *lipid-P↓, *↓, *tau↓, *cognitive↑,
6054- RES,  SeNPs,    Oral Administration of Resveratrol-Selenium-Peptide Nanocomposites Alleviates Alzheimer's Disease-like Pathogenesis by Inhibiting Aggregation and Regulating Gut Microbiota
- in-vivo, AD, NA
*Dose↝, *cognitive↑, *↓, *ROS↓, *TAC↑, *GutMicro↑, *BBB↑,
3612- RES,    Resveratrol in Alzheimer's disease: a review of pathophysiology and therapeutic potential
- Review, AD, NA
*other↑, *↓, *Inflam↓, *NF-kB↓, *neuroP↑, *HO-1↑, *lipid-P↓, *COX2/PTGS2↓, *AMPK↑, *Catalase↑, *SOD↑, *GSR↑, *ROS↓, *MMP9↓, *cognitive↑, *SIRT1↑, *IL1β↓, *IL6↓,
3613- RES,    Resveratrol for Alzheimer's disease
- Review, AD, NA
*SIRT1↑, *BioAv↝, *toxicity↓, *ROS↓, *antiOx↑, *↓, *MMP9↓, *TNF-α↓,
4286- RES,    Neuroprotective Properties of Resveratrol and Its Derivatives—Influence on Potential Mechanisms Leading to the Development of Alzheimer’s Disease
- Review, AD, NA
*neuroP↑, *Inflam↓, *antiOx↑, *GSH↑, *HO-1↑, *iNOS↓, *BDNF↑, *p‑CREB↑, *PKA↑, *Bcl-2↑, *BAX↓, *IL1β↓, *IL6↓, *MMP9↓, *memory↑, *AMPK↑, *PGC-1α↓, *NF-kB↓, *↓, *SIRT1↑, *p‑tau↓, *PP2A↑, *lipid-P↓, *NLRP3↓, *BACE/β-secretase↓,
4284- RES,    Resveratrol induces dephosphorylation of Tau by interfering with the MID1-PP2A complex
- in-vitro, AD, HEK293 - NA, Stroke, NA - in-vivo, AD, NA
*p‑tau↓, *PP2A↑, *neuroP↑, *antiOx↑, COX2/PTGS2↓, *AntiAg↑, *SIRT1↑, *AMPK↑, *Acetyl-CoA↓, *FAO↑, *ADAM10↑, *BACE/β-secretase↓, *↓, *memory↑, *Inflam↓, *ROS↓,
6417- RES,  CUR,    Curcumin and Resveratrol Synergy: A Multi-Target Strategy Against Neurodegenerative Disease Pathology
- Review, AD, NA
*neuroP↑, *NRF2↝, *ARE↝, *NF-kB↓, *↓, *ROS↓, *Inflam↓, *BioAv↓,
3080- RES,    Resveratrol: A miraculous natural compound for diseases treatment
- Review, Var, NA
SIRT1↑, ROCK1↓, AMPK↑, *lipid-P↓, ↓, COX2/PTGS2↓, angioG↓, Hif1a↓, VEGF↓,
3100- RES,    Neuroprotective effects of resveratrol in Alzheimer disease pathology
- Review, AD, NA
*neuroP↑, *BioAv↓, *Half-Life↓, *BioAv↑, *BBB↑, *NRF2↑, *BioAv↓, *BioAv↑, *SIRT1↑, *cognitive↑, *lipid-P↓, *HO-1↑, *SOD↑, *GSH↑, *GPx↑, *G6PD↑, *PPARγ↑, *AMPK↑, *↓,
3057- RES,    The therapeutic effect of resveratrol: Focusing on the Nrf2 signaling pathway
- Review, Var, NA - Review, AD, NA - Review, Stroke, NA
*NRF2↑, *Keap1↓, *ROS↓, *Apoptosis↓, *Inflam↓, *antiOx↑, *hepatoP↑, *neuroP↑, *cardioP↑, *RenoP↑, *AntiCan↑, *memory↑, *SOD↑, *GPx↑, *Catalase↑, *MDA↓, *NRF2↑, *HO-1↑, *ROS↓, *↓, *iNOS↓, *COX2/PTGS2↓, *GSH↑, *HO-1⇅, *SIRT1↑,
3729- RF,    Review of the Evidence that Transcranial Electromagnetic Treatment will be a Safe and Effective Therapeutic Against Alzheimer's Disease
- in-vivo, AD, NA
*cognitive↑, *↓, *ROS↓, *ATP↑,
3730- RF,    Transcranial electromagnetic treatment against Alzheimer's disease: why it has the potential to trump Alzheimer's disease drug development
- Review, AD, NA
*cognitive↑, *↓,
3731- RF,    Electromagnetic field treatment protects against and reverses cognitive impairment in Alzheimer's disease mice
- in-vivo, AD, NA
*cognitive↑, *↓, *neuroP↑, *memory↑,
3732- RF,    Electromagnetic treatment to old Alzheimer's mice reverses β-amyloid deposition, modifies cerebral blood flow, and provides selected cognitive benefit
- in-vivo, AD, NA
*cognitive↑, *↓,
3733- RF,    Long-term electromagnetic field treatment enhances brain mitochondrial function of both Alzheimer's transgenic mice and normal mice: a mechanism for electromagnetic field-induced cognitive benefit?
- in-vivo, AD, NA
*↓, *cognitive↑, *mt-ROS↓, *ATP↑,
3738- RF,    Electromagnetic Field Stimulation Therapy for Alzheimer's Disease
- Review, AD, NA
*cognitive↑, *↓, *ROS↓, *memory↑, *Inflam∅,
3743- RF,    Repeated electromagnetic field stimulation lowers amyloid-β peptide levels in primary human mixed brain tissue cultures
- in-vitro, AD, NA
*↓, *toxicity∅, *APP∅,

Showing Research Papers: 201 to 250 of 334
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 334

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1)

ROS↓, 1,   ROS↑, 2,  

Mitochondria & Bioenergetics(tgid=3)

AIF↑, 1,   MMP↓, 2,  

Core Metabolism/Glycolysis(tgid=4)

AMPK↑, 1,   cMyc↓, 1,   GlucoseCon↓, 1,   Glycolysis↓, 1,   HK2↓, 1,   lactateProd↓, 1,   LDH↑, 1,   NAD↑, 1,   SIRT1↑, 1,  

Cell Death(tgid=5)

Akt↓, 1,   Apoptosis↑, 2,   BAX↓, 1,   Casp12↑, 1,   Cyt‑c↑, 2,   Endon↑, 1,   MDM2↓, 1,  

Kinase & Signal Transduction(tgid=6)

Sp1/3/4↓, 1,  

Transcription & Epigenetics(tgid=7)

tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8)

CHOP/DDIT3↑, 1,   GRP78/BiP↑, 1,   HSP70/HSPA5↓, 1,   HSP90↓, 1,  

DNA Damage & Repair(tgid=10)

cl‑PARP↑, 1,  

Cell Cycle & Senescence(tgid=11)

CDK1↓, 1,   CDK2↓, 1,   CDK4↓, 2,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 1,   P21↑, 1,   TumCCA↑, 2,  

Proliferation, Differentiation & Cell State(tgid=12)

Diff↓, 1,   EMT↓, 2,   ERK↓, 2,   mTOR↓, 1,   PI3K↓, 1,   RAS↓, 1,   STAT↓, 1,   STAT3↓, 2,   STAT4↓, 1,   TOP2↓, 1,   Wnt↓, 1,  

Migration(tgid=13)

AP-1↓, 1,   Ca+2↑, 1,   KRAS↓, 1,   MMP2↓, 3,   MMP9↓, 1,   MMPs↓, 1,   PKA↓, 1,   PKCδ↓, 1,   ROCK1↓, 1,   Slug↓, 1,   TumCI↓, 1,   TumCMig↓, 2,   TumCP↓, 3,   TumMeta↓, 2,   Twist↓, 1,   α-SMA↓, 1,   α-SMA↑, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 1,   Hif1a↓, 1,   NO↓, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15)

P-gp/ABCB1↓, 2,  

Immune & Inflammatory Signaling(tgid=16)

COX2/PTGS2↓, 3,   CRP↓, 1,   Inflam↓, 1,   JAK↓, 1,   JAK2↓, 1,   NF-kB↓, 1,  

Protein Aggregation(tgid=19)

↓, 1,  

Hormonal & Nuclear Receptors(tgid=20)

CDK6↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 1,   ChemoSen↑, 1,   Dose↓, 1,   eff↑, 7,   selectivity↑, 3,  

Clinical Biomarkers(tgid=22)

CRP↓, 1,   KRAS↓, 1,   LDH↑, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 1,   memory↑, 1,   TumVol↓, 1,  
Total Targets: 87

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0)

AntiArt↑, 1,   autophagy↓, 1,   MEF2D↑, 1,   NeuroI↓, 1,  

Redox & Oxidative Stress(tgid=1)

antiOx↑, 12,   ARE↝, 1,   Catalase↑, 5,   GPx↑, 4,   GSH↑, 6,   GSR↑, 1,   HDL↓, 1,   HO-1↑, 7,   HO-1⇅, 1,   Iron↓, 1,   Keap1↓, 1,   lipid-P↓, 8,   MDA↓, 4,   Nrf1↑, 1,   NRF2↓, 1,   NRF2↑, 6,   NRF2↝, 1,   ROS?, 1,   ROS↓, 26,   mt-ROS↓, 1,   SOD↑, 6,   SOD1↑, 1,   TAC↑, 1,   Trx1↑, 1,  

Metal & Cofactor Biology(tgid=2)

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3)

ATP↑, 3,   MMP↑, 1,   PGC-1α↓, 1,  

Core Metabolism/Glycolysis(tgid=4)

Acetyl-CoA↓, 1,   AMPK↑, 5,   p‑CREB↑, 1,   FAO↑, 1,   G6PD↑, 1,   LDL↓, 1,   NADPH↓, 1,   PPARγ↑, 1,   SIRT1↑, 7,  

Cell Death(tgid=5)

Akt↓, 1,   p‑Akt↓, 1,   Apoptosis↓, 4,   BAX↓, 1,   Bcl-2↑, 1,   iNOS↓, 5,   p‑JNK↓, 1,   MAPK↓, 1,   p‑p38↓, 1,  

Transcription & Epigenetics(tgid=7)

Ach↑, 1,   other↑, 1,   other↝, 1,  

Protein Folding & ER Stress(tgid=8)

HSP70/HSPA5↓, 1,  

DNA Damage & Repair(tgid=10)

DNAdam↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

cFos↑, 1,   ERK↓, 1,   FGF↑, 1,   GSK‐3β↓, 3,   mTOR↓, 2,   PI3K↓, 1,   STAT3↓, 1,   p‑STAT3↓, 1,  

Migration(tgid=13)

AntiAg↑, 1,   APP↓, 2,   APP∅, 2,   ARG1/2↑, 1,   Ca+2↝, 1,   cal2↓, 1,   LRP1↑, 1,   MMP-10↓, 1,   MMP1↓, 1,   MMP9↓, 5,   PKA↑, 1,   p‑SMAD2↓, 1,   SPARC↓, 1,   TGF-β1↑, 1,   TIMP1↑, 1,   TIMP2↑, 1,   TXNIP↓, 1,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 1,   NO↓, 2,   VEGF↓, 1,  

Barriers & Transport(tgid=15)

BBB↑, 5,   BBB↝, 1,  

Immune & Inflammatory Signaling(tgid=16)

COX2/PTGS2↓, 4,   IFN-γ↓, 1,   p‑IKKα↓, 1,   IL1↓, 1,   IL10↓, 1,   IL10↑, 1,   IL17↓, 2,   IL1β↓, 5,   IL23↓, 1,   IL4↑, 1,   IL6↓, 5,   Inflam↓, 18,   Inflam∅, 2,   p‑IκB↓, 1,   MCP1/CCL2↓, 2,   MyD88↓, 1,   NF-kB↓, 6,   p‑p65↓, 1,   TLR4↓, 2,   TNF-α↓, 4,  

Cellular Microenvironment(tgid=17)

NOX↓, 1,  

Synaptic & Neurotransmission(tgid=18)

5HT↑, 1,   AChE↓, 7,   ADAM10↑, 2,   BDNF↑, 8,   NGF↑, 2,   PSD95↑, 2,   tau↓, 3,   p‑tau↓, 8,  

Protein Aggregation(tgid=19)

AEP↓, 1,   ?, 1,   ↓, 46,   ∅, 2,   BACE/β-secretase↓, 6,   BACE/β-secretase↝, 1,   IDE↑, 1,   NEP↑, 1,   NLRP3↓, 2,   PP2A↑, 2,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20)

ER(estro)↑, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 4,   BioAv↑, 2,   BioAv↝, 1,   Dose↝, 5,   eff↑, 6,   Half-Life↓, 1,   Half-Life↑, 1,  

Clinical Biomarkers(tgid=22)

BP↓, 1,   GutMicro↑, 3,   IL6↓, 5,  

Functional Outcomes(tgid=23)

AntiCan↑, 1,   AntiDiabetic↑, 1,   cardioP↑, 3,   cognitive↑, 33,   cognitive∅, 2,   hepatoP↑, 2,   memory↑, 19,   memory∅, 2,   Mood↑, 1,   motorD↑, 3,   neuroP↑, 28,   Pain↓, 1,   RenoP↑, 1,   STEP↓, 1,   toxicity↓, 1,   toxicity∅, 1,   Weight∅, 1,  

Infection & Microbiome(tgid=24)

AntiViral↑, 1,   Bacteria↓, 1,  
Total Targets: 156

Scientific Paper Hit Count for: , aggregation
19 Selenium NanoParticles
17 Curcumin
14 Resveratrol
14 Ferulic acid
14 Urolithin
12 Magnetic Fields
9 EGCG (Epigallocatechin Gallate)
9 Emodin
8 Berberine
8 Chlorogenic acid
8 Thymoquinone
7 Alpha-Lipoic-Acid
7 Mung Bean Sprouts
7 Hydrogen Gas
7 Quercetin
7 Rosmarinic acid
6 Rutin
6 Folic Acid, Vit B9
6 EMF
5 isoquercitrin
5 Ashwagandha(Withaferin A)
5 Carnosine
5 Crocetin
5 Magnetic Field Rotating
5 Mushroom Lion’s Mane
5 Sulforaphane (mainly Broccoli)
4 Apigenin (mainly Parsley)
4 Capsaicin
4 Cinnamon
4 Ginseng
4 Hyperoside
4 Luteolin
4 Silymarin (Milk Thistle) silibinin
4 Vitamin B1/Thiamine
3 beta-carotene(VitA)
3 Cichoric acid / Chicoric acid
3 Fisetin
3 Flickering Light Stimulation
3 Honokiol
3 HydroxyTyrosol
3 isoorientin
3 Kaempferol
3 Licochalcone A
3 Radio Frequency
3 Vitamin B3,Niacin
3 Vitamin B5,Pantothenic Acid
3 Vitamin D3
3 Vitamin K2
2 Aromatherapy
2 Huperzine A/Huperzia serrata
2 Bacopa monnieri
2 borneol
2 Boron
2 Boswellia (frankincense)
2 α-Bisabolol / Chamomile oil
2 Caffeic acid
2 Centella asiatica / Gotu kola → asiaticoside
2 Choline
2 Echinacea
2 Vitamin E
2 diet Short Term Fasting
2 D-limonene
2 Eugenol
2 Angelica archangelica / Garden Angelica
2 Ginkgo biloba
2 Ginkgetin
2 hydrogen sulfide
2 Isobavachalcone
2 Isovitexin
2 MCToil
2 Moringa oleifera
2 chitosan
2 Taurine
1 1,8-Cineole
1 Annona atemoya Leaf Extract
1 Anthocyanins
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Astaxanthin
1 Carnosic acid
1 Celastrol
1 Chrysin
1 Coenzyme Q10
1 Rivastigmine
1 Galantamine
1 Cysteamine
1 Date Fruit Extract
1 diet Fermented Foods
1 Ginkgo biloba-EGb 761
1 Phosphatidylserine
1 flavonoids
1 Exercise
1 Auditory Gamma Stimulation / 40 Hz Auditory Stimulation
1 Fucoidan
1 Shilajit/Fulvic Acid
1 Iron
1 Gallic acid
1 Ginkgolide B
1 Oleuropein
1 Isoliquiritigenin
1 isoflavones
1 Morin
1 Lutein
1 Zeaxanthin
1 Lycopene
1 Vitexin
1 Methylsulfonylmethane
1 Myricetin
1 Nimbolide
1 Protocatechuic acid
1 Piperine
1 Piperlongumine
1 Salvia officinalis
1 S-adenosyl-L-methionine
1 Carvacrol
1 Sesame seeds and Oil
1 Silicic Acid
1 Spermidine
1 Ursolic acid
1 Vanillic Acid
1 Vitamin A, Retinoic Acid
1 Vitamin B12
1 Vitamin B2,Riboflavin
1 probiotics
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1333  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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