BDNF Cancer Research Results

BDNF, brain-derived neurotrophic factor: Click to Expand ⟱
Source:
Type:
Brain-Derived Neurotrophic Factor (BDNF) is a key neurotrophin (a type of growth factor) involved in brain health, and its role in Alzheimer’s Disease (AD) has been extensively studied.
-AD patients often have lower BDNF levels in key brain regions, such as the hippocampus and cortex.
-This reduction correlates with cognitive decline and brain atrophy.
-BDNF normally protects neurons from Aβ toxicity
-Exercise and cognitive training have been shown to boost BDNF levels and may slow cognitive decline.
- natural compounds (like curcumin or flavonoids) may also upregulate BDNF.
Scientific Papers found: Click to Expand⟱
4878- Uro,    Activation of the Gut–Brain Interaction by Urolithin A and Its Molecular Basis
- Review, AD, NA
*memory↑, *SIRT1↑, *cognitive↑, *BDNF↑, *Apoptosis↓, *neuroG↑,
4880- Uro,    Urolithins: A Prospective Alternative against Brain Aging
- Review, AD, NA
*cognitive↑, *memory↑, *antiOx↑, *BBB↑, *ROS↓, *lipid-P↓, *Catalase↑, *SOD↑, *GSR↑, *GPx↑, *CREB↑, *BDNF↑, *neuroP↑, *Inflam↓, *MitoP↑, *Aβ↓, *tau↓, *NLRP3↓, *SIRT1↑, *SIRT3↑,
4181- VitB6,    Vitamin B6 prevents cognitive impairment in experimental pneumococcal meningitis
- in-vivo, NA, NA
*BDNF↑, *memory↑,
4183- VitD3,  Ex,    Combined Exercise and Vitamin D on Brain-Derived Neurotrophic Factor
- Review, NA, NA
*BDNF↑, *Inflam↓, *other↝,
4184- VitD3,    Neuroplasticity-related effects of vitamin D relevant to its neuroprotective effects: A narrative review
- Review, NA, NA
*BDNF↑, *cognitive↑,
4185- VitD3,    Effects of vitamin D supplementation on neuroplasticity in older adults: a double-blinded, placebo-controlled randomised trial
- Study, NA, NA
*other↑, *BDNF∅,
4186- VitD3,    The Association of Vitamin D, Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF), and Glial Cell-Derived Neurotrophic Factor (GDNF) with Development in Children
- Study, NA, NA
*BDNF∅,
4187- VitD3,    Protective effects of vitamin D on neurophysiologic alterations in brain aging: role of brain-derived neurotrophic factor (BDNF)
- in-vivo, NA, NA
*BDNF↑, *MDA↓, *Casp3↓,
4182- VitD3,    The association between vitamin D and BDNF on cognition in older adults in Southern Brazil
- Study, AD, NA
*cognitive↑, *BDNF↑,
4179- VitE,    Vitamin E protects against oxidative damage and learning disability after mild traumatic brain injury in rats
- in-vivo, NA, NA
*BDNF↑,
4188- VitK2,    Vitamin K2 protects against aluminium chloride-mediated neurodegeneration
- in-vivo, NA, NA
*BDNF↑, *Aβ↓, *cognitive↑, *Ach↑, *Inflam↓,
7902- VT,    Vitexin Protects Against Scopolamine-Induced Cognitive Impairment by Preserving Synaptic Integrity and Modulating Nrf2/HO-1 and NF-κB Signaling Pathways
- in-vivo, AD, NA
*Dose↝, *Learn↑, *memory↑, *AChE↓, *lipid-P↓, *TOS↓, *MDA↓, *ONOO↓, *NO↓, *NOS2↓, *TAC↑, *BDNF↑, *GDNF↑, *PSD95↑, *GFAP↓, *NF-kB↓, *COX2/PTGS2↓, *NRF2↑, *HO-1↑, *neuroP↑, *NeuroI↓,
4196- Z,    The effect of zinc supplementation on brain derived neurotrophic factor: A meta-analysis
- Review, NA, NA
*BDNF∅,
4197- Z,    The Effect of Zinc Supplementation on Circulating Levels of Brain-Derived Neurotrophic Factor (BDNF): A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- Review, NA, NA
*BDNF↑, *other↓, *eff↑, *Inflam↓, *antiOx↑,
4166- Z,    Zinc monotherapy increases serum brain-derived neurotrophic factor (BDNF) levels and decreases depressive symptoms in overweight or obese subjects: a double-blind, randomized, placebo-controlled trial
- Trial, Obesity, NA
*BDNF↑, *Mood↑,
4165- Z,    Antidepressant-like activity of zinc: further behavioral and molecular evidence
- in-vivo, AD, NA
*BDNF↑,
4164- Z,    Zinc treatment induces cortical brain-derived neurotrophic factor gene expression
- Review, AD, NA
*BDNF↑,
4191- Zeax,  Lut,    Effects of macular xanthophyll supplementation on brain-derived neurotrophic factor, pro-inflammatory cytokines, and cognitive performance
- Trial, AD, NA
*BDNF↑, *IL1β↓, *cognitive↑, *memory↑,

Showing Research Papers: 201 to 218 of 218
Prev Page 5 of 5

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 218

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

GDNF↑, 1,   GFAP↓, 1,   Learn↑, 1,   NeuroI↓, 1,   ONOO↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 2,   Catalase↑, 1,   GPx↑, 1,   GSR↑, 1,   HO-1↑, 1,   lipid-P↓, 2,   MDA↓, 2,   NRF2↑, 1,   ROS↓, 1,   SIRT3↑, 1,   SOD↑, 1,   TAC↑, 1,   TOS↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

CREB↑, 1,   SIRT1↑, 2,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,   Casp3↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ach↑, 1,   other↓, 1,   other↑, 1,   other↝, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

MitoP↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

neuroG↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   IL1β↓, 1,   Inflam↓, 4,   NF-kB↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   BDNF↑, 15,   BDNF∅, 3,   PSD95↑, 1,   tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 2,   NLRP3↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 1,   eff↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

NOS2↓, 1,  

Functional Outcomes(tgid=23) ⓘ

cognitive↑, 6,   memory↑, 5,   Mood↑, 1,   neuroP↑, 2,  
Total Targets: 48

Scientific Paper Hit Count for: BDNF, brain-derived neurotrophic factor
11 Exercise
10 Hydrogen Gas
9 Magnetic Fields
6 Curcumin
6 Lycopene
6 Silymarin (Milk Thistle) silibinin
6 Vitamin D3
5 Apigenin (mainly Parsley)
5 Sulforaphane (mainly Broccoli)
5 Zinc
4 Ellagic acid
4 Ginseng
4 Honokiol
4 Huperzine A/Huperzia serrata
4 isoorientin
4 Lutein
4 Resveratrol
3 Carnosic acid
3 Caffeine
3 Cysteamine
3 Ferulic acid
3 Ginkgolide B
3 Naringin
3 Piperine
3 Urolithin
2 flavonoids
2 Aromatherapy
2 Baicalin
2 Berberine
2 Boron
2 Boswellia (frankincense)
2 Centella asiatica / Gotu kola → asiaticoside
2 Choline
2 Folic Acid, Vit B9
2 Chrysin
2 Cichoric acid / Chicoric acid
2 Coenzyme Q10
2 Crocetin
2 Docosahexaenoic Acid
2 diet Short Term Fasting
2 Eugenol
2 Ginkgo biloba
2 Ginger/6-Shogaol/Gingerol
2 Hyperoside
2 Kaempferol
2 Mung Bean Sprouts
2 Luteolin
2 Zeaxanthin
2 Magnesium
2 Phenylbutyrate
2 Propolis -bee glue
2 Quercetin
2 Sesame seeds and Oil
2 Taurine
2 Thymoquinone
2 Ursolic acid
1 Annona atemoya Leaf Extract
1 isoquercitrin
1 Rutin
1 Anthocyanins
1 Alpha-Lipoic-Acid
1 Acetyl-l-carnitine
1 alpha Linolenic acid
1 Artemisinin
1 Astaxanthin
1 Baicalein
1 Beta-Caryophyllene
1 Betulinic acid
1 Bacopa monnieri
1 Caffeic acid
1 Capsaicin
1 Carvacrol
1 Carnosine
1 chitosan
1 Vitamin B12
1 Vitamin B2,Riboflavin
1 Echinacea
1 Cinnamon
1 Cynara scolymus/Globe Artichoke/Artichoke Extract
1 dietMediterranean
1 2-DeoxyGlucose
1 Calorie Restriction Mimetics
1 EGCG (Epigallocatechin Gallate)
1 Emodin
1 Phosphatidylserine
1 Fisetin
1 Formononetin
1 Gallic acid
1 Galantamine
1 Bifidobacterium animalis subsp. lactis GCL2505
1 Isoliquiritigenin
1 Licochalcone A
1 Lecithin
1 Magnolol
1 Magnetic Field Rotating
1 Moringa oleifera
1 Methylsulfonylmethane
1 Mushroom Lion’s Mane
1 nicotinamide adenine dinucleotide
1 Protocatechuic acid
1 Polyphenols
1 probiotics
1 Pterostilbene
1 Salvia officinalis
1 Rosmarinic acid
1 Selenium
1 Shikonin
1 Selenite (Sodium)
1 Safflower yellow
1 Turmerones
1 Vitamin B6,pyridoxine
1 Vitamin E
1 Vitamin K2
1 Vitexin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1356  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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