AntiCan Cancer Research Results

AntiCan, Anticancer Effect: Click to Expand ⟱
Source:
Type: general indicator
Anticancer Effect


Scientific Papers found: Click to Expand⟱
7005- Fuc,    Fucoidan and cancer: a multifunctional molecule with anti-tumor potential
- Review, Var, NA
AntiCan↑, TumCCA↑, cycD1/CCND1↓, CDK4↓, MMP↓, Casp9↑, survivin↓, IAP1↓, Cyt‑c↑, Diablo↑, Bak↑, XIAP↓, VEGF↓, angioG↓, MMP2↓, MMP9↓, Akt↓, eff↝, TumMeta↓,
7006- Fuc,    Seaweeds in the Oncology Arena: Anti-Cancer Potential of Fucoidan as a Drug—A Review
- Review, Var, NA
*toxicity↓, *AntiViral↑, *antiOx↑, *Imm⇅, AntiCan↑, TumCCA↑, Apoptosis↑, TumMeta↓, angioG↓, antiNeop↑, VEGF↓, MMPs↓, BioAv↑, BioAv↑, ROS⇅, cl‑PARP↑, Casp3↑, Casp7↑, ROS↑, GSH↓, MMP↓, PI3K↓, ERK↓, MAPK↑, TumCP↓, Bax:Bcl2↑, TJ↑, ZO-1↑, OCLN↑, CLDN1↑, IBI↑, GutMicro↑, NK cell↑, STAT3↓, eff↑,
1773- GA,    Impact of Gallic Acid on Gut Health: Focus on the Gut Microbiome, Immune Response, and Mechanisms of Action
- Review, Var, NA
antiOx↑, AntiCan↑, Inflam↓, GutMicro↑, BioAv↝, BioAv↓, BioAv↑, TumMeta↓,
7048- GA,    Natural bioactive gallic acid shows potential anticancer effects by inhibiting the proliferation and invasiveness behavior in human embryonic carcinoma cells
- in-vitro, Var, NA
AntiCan↑, TumCCA↑, angioG↓, TumCMig↓, TumMeta↓, CSCs↓, Apoptosis↑, P21↑, P53↑, p27/CDKN1B↑, CDK4↓, cycE/CCNE↓, cycD1/CCND1↓, SOX2↓, Nanog↓, OCT4↓, ROS↑, DNAdam↑, BRCA1↑, ATM↑, CHK1↑, Chk2↑, Histones↑, TumCI↓, MMPs↓, EGFR↓, JAK2↓, STAT5↓,
7027- GA,    Pharmacokinetics of gallic acid and its relative bioavailability from tea in healthy humans
- Human, Nor, NA
AntiCan↑, *Inflam↓, *BioAv↑, *Half-Life↓, *eff↝,
7069- GABA,    United States Pharmacopeia (USP) Safety Review of Gamma-Aminobutyric Acid (GABA)
- Review, Nor, NA
*toxicity↓, *BP↓, *AntiDiabetic↑, *AntiCan↑, *antiOx↑, *Inflam↓, *AntiBio↑, *other↝, *cognitive↑, *GH↑, *Sleep↑, *BioAv↑, *Half-Life↝, *BBB↓, *eff↑,
5152- GamB,    Gambogic Acid as a Candidate for Cancer Therapy: A Review
- Review, Var, NA
AntiCan↑, Apoptosis↑, TumAuto↑, TumCCA↑, TumCI↓, TumMeta↓, angioG↓, eff↑, NF-kB↓, P53↑, P21↑, MDM2↓, HSP90↓, Bcl-2↓, Cyt‑c↑, Casp↑, MMP↓, Casp3↑, Casp9↑, cl‑PARP↑, Bax:Bcl2↑, ROS↑, SIRT1↓, TrxR1↓, Fas↓, FasL↑, FADD↑, APAF1↑, DNAdam↑, NF-kB↓, STAT3↓, MAPK↓, cFos↓, EGFR↓, Akt↓, mTOR↓, AMPK↑, TumCCA↑, ChemoSen↑, P-gp/ABCB1↓, survivin↓,
5148- GamB,    Gambogic acid: A shining natural compound to nanomedicine for cancer therapeutics
- Review, Var, NA
AntiCan↑, angioG↓, ChemoSen↑, RadioS↑, VEGF↓, MMP2↓, MMP9↓, Telomerase↓, TrxR↓, ERK↓, HSP90↓, ROS↑, SIRT1↑, survivin↓, cFLIP↓, Casp3↑, Casp8↑, Casp9↑, BAD↓, BID↓, Bcl-2↓, BAX↑, STAT3↓, hTERT/TERT↓, NF-kB↓, Myc↓, Hif1a↓, FOXD3↑, BioAv↓, BioAv↑, P53↑, eff↓, OCR↓, MMP↓, PI3K↓, Akt↓, BBB↑, TumCG↓, TumMeta↓, BioAv↑,
1957- GamB,    Nanoscale Features of Gambogic Acid Induced ROS-Dependent Apoptosis in Esophageal Cancer Cells Imaged by Atomic Force Microscopy
- in-vitro, ESCC, EC9706
AntiCan↑, toxicity↓, TumCP↓, Apoptosis↑, TumCCA↑, MMP↓, ROS↑, eff↓, RadioS↑,
1958- GamB,    Gambogenic acid induces apoptosis and autophagy through ROS-mediated endoplasmic reticulum stress via JNK pathway in prostate cancer cells
- in-vitro, Pca, NA - in-vivo, NA, NA
AntiCan↑, TumCP↓, TumAuto↑, eff↑, JNK↑, ROS↑, ER Stress↑, eff↓, TumCG↓,
1959- GamB,    Gambogic acid induces GSDME dependent pyroptotic signaling pathway via ROS/P53/Mitochondria/Caspase-3 in ovarian cancer cells
- in-vitro, Ovarian, NA - in-vivo, NA, NA
AntiCan↑, Pyro↑, tumCV?, CellMemb↓, cl‑Casp3↑, GSDME-N↑, ROS?, p‑P53↑, eff↓, MMP↓, Bcl-2↓, BAX↑, mtDam↑, Cyt‑c↑, TumCG↓, CD4+↑, CD8+↑,
1965- GamB,  doxoR,    Gambogic acid sensitizes ovarian cancer cells to doxorubicin through ROS-mediated apoptosis
- in-vitro, Ovarian, SKOV3
eff↑, AntiCan↑, ROS↑, ChemoSen↑,
7060- GamB,    New targets for the antitumor activity of gambogic acid in hematologic malignancies
- Review, Melanoma, RPMI-8226
AntiCan↑, TumCP↓, Apoptosis↑, SRC3↓, DIDO1/DIO-1↑, KCNH2/hERG↓, ROS↑, Bcl-2↓, P53↑, cMyc↓, VEGF↓, Casp3↑, cl‑PARP1↑, eff↓,
7086- GAR,    Garcinol: An emerging epigenetic modifier with versatile anticancer properties
- Review, Var, NA
AntiCan↑, TumCG↓, TumMeta↓, toxicity↓, Apoptosis↑, angioG↓, *BioAv↝, HATs↓, p300↓, CBP↓, PI3K↓, Akt↓, NF-kB↓, STAT↓, mTOR↓, DFF45↓, survivin↓, N-cadherin↓, Twist↓, MMP2↓, MMP3↓, MMP9↓, Mcl-1↓, EZH2↓, NOTCH↓, CXCR4↓, PGE2↓, VEGF↓, mPGES-1↓, CycB/CCNB1↓, CDK2↓, CDK4/6↓, iNOS↓, COX2/PTGS2↓, IL1↓, TNF-α↓, PARP↑, Bcl-2↓,
7092- GAR,    Garcinol and Its Role in Chronic Diseases
- Review, Var, NA
antiOx↑, Inflam↓, AntiCan↑, NF-kB↓, STAT3↓, antiNeop↑, 5LO↓, eff↑, HATs↓, p300↓, PCAF↓, miR-200c↑, NOTCH1↓, CSCs↓, COX2/PTGS2↓, cycD1/CCND1↓, VEGF↓, PI3K↓, Akt↓, Wnt↑, β-catenin/ZEB1↓, ROS↑, CHOP/DDIT3↑, Bax:Bcl2↑, Casp8↑, FAK↓, *neuroP↑, PCNA↓, *GSTs↑,
7093- GAR,    Garcinol
- Review, AD, NA
*AChE↓, *BChE↓, *HATs↓, *Inflam↓, AntiCan↑,
7215- GBE,  Cisplatin,    Ginkgetin derived from Ginkgo biloba leaves enhances the therapeutic effect of cisplatin via ferroptosis-mediated disruption of the Nrf2/HO-1 axis in EGFR wild-type non-small-cell lung cancer
- vitro+vivo, NSCLC, NA
AntiCan↑, TumAuto↑, ChemoSen↑, Iron↑, lipid-P↑, Ferroptosis↑, xCT/SLC7A11↓, GPx4↓, GSH/GSSG↓, ROS↑, NRF2↓, HO-1↓, MMP↓,
7126- Ge-132,    Immune activation of Bio-Germanium in a randomized, double-blind, placebo-controlled clinical trial with 130 human subjects: Therapeutic opportunities from new insights
- Trial, Nor, NA
AntiTum↑, AntiCan↑, *AntiAge↑, *AntiViral↑, *Inflam↓, *NK cell↑, *Imm↑, *TNF-α↑,
7124- Ge-132,    Physiological Activity of Trace Element Germanium including Anticancer Properties
- Review, Var, NA
*toxicity↓, Risk↓, Dose↝, AntiCan↑, AntiTum↑, Inflam↓, OXPHOS↝, *toxicity↓, *toxicity↓, other↑, eff↑, *Bacteria↓, *AntiFungal↑, eff↑, eff↑, ROS↑, eff↑, toxicity↝, *H2O2↓, *ROS↓, Warburg↓,
7101- Geld,    Reactive oxygen species mediate hepatotoxicity induced by the Hsp90 inhibitor geldanamycin and its analogs
- in-vitro, Nor, NA
*toxicity↑, *AntiBio↑, HSP90↓, AntiCan↑,
7103- GEN,    A Comprehensive Review of Genistein's Effects in Preclinical Models of Cervical Cancer
- Review, Cerv, NA
TumCP↓, Apoptosis↑, RadioS↑, ChemoSen↑, *antiOx↑, *Inflam↓, *Bacteria↓, *AntiViral↑, *AntiDiabetic↑, *neuroP↑, AntiCan↑, TumCG↓, TumCI↓, TumCCA↑, cl‑PARP↑, selectivity↑, CycB/CCNB1↓, CDK1↓, p‑cDC2↓, p‑ERK↓, p‑p38↑, p‑JNK↑, MMP9↓, TIMP1↑, BioAv↓, BioAv↑, Half-Life↑,
6562- Ger,    Potential Effects of Geraniol on Cancer and Inflammation-Related Diseases: A Review of the Recent Research Findings
- Review, Var, NA - Review, AD, NA
*Inflam↓, *AntiCan↑, *AntiBio↑, *antiOx↑, *neuroP↑, ROS↓, Apoptosis↑, TumCCA↑, P53↝, STAT3↓, Casp↝, *Catalase↑, *GSTs↑, *GPx↑, *AChE↓, *GSH↑, *SOD↑, *TBARS↓, *NO↓, *XO↓, *memory↑, *IL1β↓, *iNOS↓, *NF-kB↓, *COX2/PTGS2↓, *NRF2↑, *HO-1↑, *survivin↓, TumCP↓, TumCMig↓, TumCG↑, selectivity↑, TumMeta↓, angioG↓, Hif1a↓, Beclin-1/ATG6↓,
6565- Ger,    Geraniol and geranyl acetate induce potent anticancer effects in colon cancer Colo-205 cells by inducing apoptosis, DNA damage and cell cycle arrest
- in-vitro, CRC, COLO205
AntiCan↑, mt-Apoptosis↑, BAX↑, Bcl-2↓, DNAdam↑, TumCCA↑,
6570- Ger,    Apoptosis-Mediated Anticancer Activity of Geraniol Inhibits NF-κB, MAPK, and JAK-STAT-3 Signaling Pathways in Human Thyroid Cancer Cells
- in-vitro, Thyroid, TPC-1
*Inflam↓, AntiCan↑, *neuroP↑, tumCV↓, TumCP↓, ROS↑, Apoptosis?, MMP↓, Bcl-2↓, cycD1/CCND1↓, cMyc↓, COX2/PTGS2↓, TNF-α↓, NF-kB↓, IL6↓, survivin↓, BAX↑, Casp3↑, JAK2↓, STAT3↓, ERK↓,
7142- GI,    Phase II study of the Effects of Ginger Root Extract on Eicosanoids in Colon Mucosa in People at Normal Risk for Colorectal Cancer
- Trial, Nor, NA
COX2/PTGS2↓, *PGE2↓, *5-HETE↓, *12-HETE↓, *Eic↓, *AntiCan↑, *antiOx↑, *Inflam↓, 5LO↓, eff↝,
7250- Gink,    Ginkgetin from Ginkgo biloba: mechanistic insights into anticancer efficacy
- Review, Var, NA
AntiCan↑, toxicity↓, ChemoSen↑, chemoP↑, TumCCA↑, TumCD↑, TumCI↓, angioG↓, Ferroptosis↑, Imm↑, MOMP↑, Cyt‑c↑, Casp↑, cl‑Casp3↑, cl‑Casp9↑, cl‑PARP↑, Apoptosis↑, ROS↑, TumAuto↑, GPx4↓, xCT/SLC7A11↓, RadioS↑, NRF2↓, HO-1↓, HSP90↓, Dose↝, Dose↝, BioAv↓, BioAv↝, CYP3A4↓, *toxicity↑, *toxicity↝,
7251- Gink,    Ginkgetin: A Promising Multitarget Agent for Diverse Diseases
- Review, Var, NA
*Inflam↓, *antiOx↓, AntiCan↑, *neuroP↑, *cardioP↑, *Bacteria↓, *ROS↓, *lipid-P↓, *NRF2↓, *Keap1↓, *NF-kB↓, *MAPK↓, MMP2↓, M2 MC↓, JAK2↓, STAT3↓, TumCP↓, Casp↑, ChemoSen↑, *BMD↑, *Aβ↓, *Stroke↓, *BioAv↓,
7260- Gink,    Ginkgetin: A natural biflavone with versatile pharmacological activities
- Review, Var, NA - Review, Stroke, NA - Review, AD, NA
*AntiCan↑, *Inflam↓, *AntiBio↑, *neuroP↑, *TumCCA↑, Apoptosis↑, TumAuto↑, iNOS↓, COX2/PTGS2↓, PGE2↓, NF-kB↓, PLA2↓, *neuroP↑, *Stroke↓, *AntiFungal↓, *Bacteria↓, Bcl-xL↓, Bcl-2↓, Casp9↑, Casp3↑, cl‑PARP↑, IL6↓, STAT3↓, JAK1↓, survivin↓, COX2/PTGS2↓, IAP1↓, MMP2↓, MMP9↓, PTEN↑, SHP1↑, eff↑, TumVol↓, TumW↓, *toxicity↓, *ROS↓,
4508- GLA,  aLinA,    α-Linolenic and γ-linolenic acids exercise differential antitumor effects on HT-29 human colorectal cancer cells
- in-vitro, Colon, HT29
Apoptosis↑, *Inflam↓, AntiCan↑, lipid-P↑, COX2/PTGS2↝, MKP1↝,
7338- Gra,    Pharmacological Activities of Soursop (Annona muricata Lin.)
- Review, Var, NA
AntiCan↑, *AntiDiabetic↑, *Diar↓, *Bacteria↓, *AntiViral↑, *Wound Healing↑, MMP2↓, MMP9↓, MMP↓, ROS↑, TumCCA↑, BAX↑, Bcl-2↓, Casp3↑, *BAX↓, *MDA↓, *Catalase↑, *SOD↑, *GSH↑, *NO↑, *PGE2↑, *HSP70/HSPA5↑,
7330- GSE,    Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention
- Review, Var, NA
*BioAv↑, *ROS↓, AntiCan↑, selectivity↑, RenoP↑, *hepatoP↑, *DNAdam↓, *Stroke↓, *Bcl-2↑, cMyc↓,
6561- GSL,    Geraniol Pharmacokinetics, Bioavailability and Its Multiple Effects on the Liver Antioxidant and Xenobiotic-Metabolizing Enzymes
- in-vivo, Nor, NA
*Inflam↓, *antiOx↑, *neuroP↑, *AntiCan↑, *BioAv↝, *Dose↝, *toxicity↓, *Catalase↑, *NADPH↑, *GSR↑, *ALAT∅, *AST∅,
7492- H2,  Chemo,    Molecular Hydrogen Protects against Various Tissue Injuries from Side Effects of Anticancer Drugs by Reducing Oxidative Stress and Inflammation
- Review, Var, NA
*ROS↓, *antiOx↑, *Inflam↓, *chemoP↑, AntiCan↑, ChemoSen↑, chemoP↑, *BUN↓, *creat↓, *TUNEL↓, *MDA↓, *SOD↑, *Catalase↑, *NRF2↑, *BNP↓, *AST↓, *ALAT↓, *TNF-α↓, *IL1β↓, *IL6↓, *Casp3↓, *Casp9↓, *GPx↑, *E-cadherin↑, *Vim↓, *α-SMA↓, *COL1↓, *cardioP↑, *hepatoP↑, *p‑mTOR↓, *EMT↓, eff∅, *LPS↓, *TLR4↓, radioP↑,
3771- H2,    Molecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer’s Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation—Fantasy or Reality?
- Review, AD, NA - Review, Stroke, NA
*cognitive↑, AntiCan↑, *Inflam↓, *antiOx↑, *ROS↓, *neuroP↑, *SOD↑, *GPx↑, *MDA↑, *BBB↑, *OS↑, *Ca+2↓, *APP↓, *p‑tau↓,
1641- HCAs,    Lung cancer induced by Benzo(A)Pyrene: ChemoProtective effect of sinapic acid in swiss albino mice
- in-vitro, Lung, A549 - in-vivo, Lung, NA
AntiCan↑, Igs↓, lipid-P↓, ROS↑, Casp3↑, Casp9↑, ChemoSideEff↓, Dose∅,
7359- HibSad,    Novel Insight into the Cellular and Molecular Signalling Pathways on Cancer Preventing Effects of Hibiscus sabdariffa: A Review - PubMed
- Review, Var, NA
AntiCan↑, TumCP↓, Apoptosis↑, TumCCA↑, P53↑, P21↑, p27/CDKN1B↑, BAD↑, BAX↑, Casp3↑, Casp7↑, Casp8↑, Casp9↑, *AntiBio↑, *Inflam↓, *antiOx↑, *BP↓, *AntiDiabetic↑, HDAC1↓, HDAC3↓, tumCV↓, LDL↓, DNAdam↑, MMP↓, *Catalase↑, *SOD↑, *GPx↑, *GSH↑, *antiOx↑, *ROS↓, TumCMig↓, TumCI↓, selectivity↑, RAS↓, Akt↓, NF-kB↓, MMP2↓, PI3K↓, Bcl-2↓, Bcl-xL↓, PCNA↓, cycA1/CCNA1↓, cycD1/CCND1↓, cycE/CCNE↓,
7356- HibSad,    Hibiscus flower extract selectively induces apoptosis in breast cancer cells and positively interacts with common chemotherapeutics
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231
AntiCan↑, Apoptosis↑, selectivity↑, ChemoSen↑, ROS↑, MMP↓, eff↑,
7455- HNK,    Honokiol in cancer: Roles in enhancing combination therapy efficacy and preventing post-transplant malignancies
- Review, Var, NA
ChemoSen↑, Imm↝, *hepatoP↑, *cardioP↑, *neuroP↑, *AntiCan↑, *Inflam↓, *antiOx↑, eff↑, *TNF-α↓, *IL1?, *IL6?,
7454- HNK,    Updated progression of honokiol in lung cancer treatment
- Review, Lung, NA
AntiCan↑, eff↑,
2891- HNK,    Honokiol, an Active Compound of Magnolia Plant, Inhibits Growth, and Progression of Cancers of Different Organs
- Review, Var, NA
AntiCan↑, Inflam↓, antiOx↑, selectivity↑, *toxicity↓, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓, CDK4↓, TumMeta↓, NADPH↓, MMP2↓, MMP9↓, p‑mTOR↓, EGFR↓, EMT↓, SIRT1↑, SIRT3↑, EZH2↓, Snail↓, Vim↓, N-cadherin↓, E-cadherin↑, COX2/PTGS2↓, NF-kB↓, *ROS↓, Ca+2↑, ROS↑,
2082- HNK,    Revealing the role of honokiol in human glioma cells by RNA-seq analysis
- in-vitro, GBM, U87MG - in-vitro, GBM, U251
AntiCan↑, TumCP↑, TumAuto↑, Apoptosis↑, *BioAv↑, *neuroP↑, *NF-kB↑, MAPK↑, GPx4↑, Tf↑, BAX↑, Bcl-2↓, antiOx↑, Hif1a↓, Ferroptosis↑,
4523- HNK,  MAG,  BA,    Honokiol-Magnolol-Baicalin Possesses Synergistic Anticancer Potential and Enhances the Efficacy of Anti-PD-1 Immunotherapy in Colorectal Cancer by Triggering GSDME-Dependent Pyroptosis
- in-vitro, CRC, HCT116 - in-vitro, CRC, LoVo - in-vivo, CRC, HCT116
AntiCan↑, eff↑, TumCP↓, TumCCA↓, cycD1/CCND1↓, Pyro↑, Apoptosis↑, cl‑GSDME↑, Bcl-2↓, Cyt‑c↑, Casp9↑, TumCG↓,
4522- HNK,  MAG,    Honokiol Is More Potent than Magnolol in Reducing Head and Neck Cancer Cell Growth
- in-vitro, HNSCC, FaDu
AntiCan↑, tumCV↓, eff↑, survivin↓, RadioS↑,
7371- HOO,    Phytochemical characterization of peanut oil and its ozonized form to explore biological activities in vitro
Dose↝, AntiBio↑, antiOx↑, AntiCan↑, selectivity↑,
7472- Hops,    Modulation of breast cancer cell survival by aromatase inhibiting hop (Humulus lupulus L.) flavonoids
- in-vitro, BC, SkBr3
CYP19↓, TumCP↓, Apoptosis↑, AntiCan↑,
7528- HT,    Involvement of the PI3K/AKT Intracellular Signaling Pathway in the AntiCancer Activity of Hydroxytyrosol, a Polyphenol from Olea europaea, in Hematological Cells and Implication of HSP60 Levels in Its Anti-Inflammatory Activity
- NA, NA, Jurkat - NA, NA, HL-60 - NA, NA, RAW264.7
*antiOx↑, *Inflam↓, *AntiBio↑, *cardioP↑, AntiCan↑, TumCCA↑, PI3K↓, MAPK↑, ROS↑, Apoptosis↑, Casp9↑, Bcl-2↓, p‑P53↓,
4634- HT,    Hydroxytyrosol in cancer research: recent and historical insights on discoveries and mechanisms of action
- Review, Var, NA
*antiOx↑, *Inflam↓, AntiCan↑, ChemoSen↑, chemoP↑,
4633- HT,    Unlocking the effective alliance of β-lapachone and hydroxytyrosol against triple-negative breast cancer cells
- in-vitro, BC, NA
AntiCan↑, CSCs↓, antiOx↑, NQO1↑, TumCCA↑, ER Stress↑, Apoptosis↑, UPR↑,
7567- HYP,    Hyperoside: A review on its sources, biological activities, and molecular mechanisms
- Review, Var, NA
*AntiCan↑, *Bacteria↓, *AntiViral↑, *antiD↓, *RenoP↑, *hepatoP↑, *eff↑, *Sepsis↓, *AntiArt↑, *Stroke↓, TumCMig↓, TumCI↓, MTA1↓, TIMP2↓, MMP2↓, MMP↓, Cyt‑c↑, Akt↓, mTOR↓, P70S6K↓, TumAuto↑, PD-L1↓, TNF-α↓, IL1β↓, IL6↓, IL8↓, Bcl-2↓, Bcl-xL↓, BAX↑, BAD↑, Bak↑, VEGF↓, Casp3↑, Casp8↑, P53↑, GSH↓, SOD↓, Catalase↓, TAC↓, XIAP↓, ROS↓, NF-kB↓, TLR4↓, P-gp/ABCB1↓, LRP1↓, Fas↑, p27/CDKN1B↑, *cardioP↑, *AntiThr↑, *PAI-1/SERPINE1↓, *BUN↓, *ALAT↓, *AST↓, *neuroP?,
7550- HYP,    Hyperoside Induces Breast Cancer Cells Apoptosis via ROS-Mediated NF-κB Signaling Pathway
- in-vitro, BC, MCF7 - in-vitro, BC, 4T1
*Inflam↓, AntiCan↑, tumCV↓, TumCMig↓, Apoptosis↑, Bcl-2↓, XIAP↓, BAX↑, cl‑Casp3↑, ROS↓, NF-kB↓, TumVol↓,

Showing Research Papers: 201 to 250 of 440
Prev Page 5 of 9 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 440

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 1,   DIDO1/DIO-1↑, 1,   KCNH2/hERG↓, 1,   MTA1↓, 1,   PLA2↓, 1,   SRC3↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 6,   Catalase↓, 1,   Ferroptosis↑, 3,   GPx4↓, 2,   GPx4↑, 1,   GSH↓, 2,   GSH/GSSG↓, 1,   HO-1↓, 2,   Iron↑, 1,   lipid-P↓, 1,   lipid-P↑, 2,   NQO1↑, 1,   NRF2↓, 2,   OXPHOS↝, 1,   ROS?, 1,   ROS↓, 3,   ROS↑, 18,   ROS⇅, 1,   SIRT3↑, 1,   SOD↓, 1,   TAC↓, 1,   TrxR↓, 1,   TrxR1↓, 1,   xCT/SLC7A11↓, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

Tf↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↓, 12,   mtDam↑, 1,   OCR↓, 1,   XIAP↓, 3,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 1,   cMyc↓, 3,   CYP3A4↓, 1,   Histones↑, 1,   LDL↓, 1,   NADPH↓, 1,   SIRT1↓, 1,   SIRT1↑, 2,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 7,   APAF1↑, 1,   Apoptosis?, 1,   Apoptosis↑, 19,   mt-Apoptosis↑, 1,   BAD↓, 1,   BAD↑, 2,   Bak↑, 2,   BAX↑, 9,   Bax:Bcl2↑, 3,   Bcl-2↓, 15,   Bcl-xL↓, 3,   BID↓, 1,   Casp↑, 3,   Casp↝, 1,   Casp3↑, 10,   cl‑Casp3↑, 3,   Casp7↑, 2,   Casp8↑, 4,   Casp9↑, 8,   cl‑Casp9↑, 1,   CBP↓, 1,   cFLIP↓, 1,   Chk2↑, 1,   Cyt‑c↑, 6,   Diablo↑, 1,   FADD↑, 1,   Fas↓, 1,   Fas↑, 1,   FasL↑, 1,   Ferroptosis↑, 3,   cl‑GSDME↑, 1,   GSDME-N↑, 1,   hTERT/TERT↓, 1,   IAP1↓, 2,   iNOS↓, 2,   JNK↑, 1,   p‑JNK↑, 1,   MAPK↓, 1,   MAPK↑, 3,   Mcl-1↓, 1,   MDM2↓, 1,   MKP1↝, 1,   MOMP↑, 1,   Myc↓, 1,   p27/CDKN1B↑, 3,   p‑p38↑, 1,   Pyro↑, 2,   survivin↓, 7,   Telomerase↓, 1,   TumCD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

FOXD3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

EZH2↓, 2,   HATs↓, 2,   other↑, 1,   PCAF↓, 1,   tumCV?, 1,   tumCV↓, 4,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,   ER Stress↑, 2,   HSP90↓, 4,   UPR↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   TumAuto↑, 7,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 1,   BRCA1↑, 1,   CHK1↑, 1,   DFF45↓, 1,   DNAdam↑, 4,   P53↑, 6,   P53↝, 1,   p‑P53↓, 1,   p‑P53↑, 1,   PARP↑, 1,   cl‑PARP↑, 5,   cl‑PARP1↑, 1,   PCNA↓, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK2↓, 2,   CDK4↓, 3,   cycA1/CCNA1↓, 1,   CycB/CCNB1↓, 2,   cycD1/CCND1↓, 7,   cycE/CCNE↓, 3,   P21↑, 3,   TumCCA↓, 1,   TumCCA↑, 14,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

p‑cDC2↓, 1,   cFos↓, 1,   CSCs↓, 3,   EMT↓, 1,   ERK↓, 3,   p‑ERK↓, 1,   HDAC1↓, 1,   HDAC3↓, 1,   mTOR↓, 3,   p‑mTOR↓, 1,   Nanog↓, 1,   NOTCH↓, 1,   NOTCH1↓, 1,   OCT4↓, 1,   p300↓, 2,   P70S6K↓, 1,   PI3K↓, 6,   PTEN↑, 1,   RAS↓, 1,   SHP1↑, 1,   SOX2↓, 1,   STAT↓, 1,   STAT3↓, 8,   STAT5↓, 1,   TumCG↓, 6,   TumCG↑, 1,   Wnt↑, 1,  

Migration(tgid=13) ⓘ

5LO↓, 2,   Ca+2↑, 1,   CDK4/6↓, 1,   CLDN1↑, 1,   E-cadherin↑, 1,   FAK↓, 1,   LRP1↓, 1,   miR-200c↑, 1,   MMP2↓, 9,   MMP3↓, 1,   MMP9↓, 7,   MMPs↓, 2,   N-cadherin↓, 2,   Snail↓, 1,   TIMP1↑, 1,   TIMP2↓, 1,   TJ↑, 1,   TumCI↓, 6,   TumCMig↓, 5,   TumCP↓, 11,   TumCP↑, 1,   TumMeta↓, 9,   Twist↓, 1,   Vim↓, 1,   ZO-1↑, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 8,   EGFR↓, 3,   Hif1a↓, 3,   VEGF↓, 7,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   CellMemb↓, 1,   IBI↑, 1,   OCLN↑, 1,   P-gp/ABCB1↓, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   COX2/PTGS2↓, 7,   COX2/PTGS2↝, 1,   CXCR4↓, 1,   Igs↓, 1,   IL1↓, 1,   IL1β↓, 1,   IL6↓, 3,   IL8↓, 1,   Imm↑, 1,   Imm↝, 1,   Inflam↓, 4,   JAK1↓, 1,   JAK2↓, 3,   M2 MC↓, 1,   mPGES-1↓, 1,   NF-kB↓, 11,   NK cell↑, 1,   PD-L1↓, 1,   PGE2↓, 2,   TLR4↓, 1,   TNF-α↓, 3,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CYP19↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 4,   BioAv↑, 6,   BioAv↝, 2,   ChemoSen↑, 11,   Dose↝, 4,   Dose∅, 1,   eff↓, 5,   eff↑, 15,   eff↝, 2,   eff∅, 1,   Half-Life↑, 1,   RadioS↑, 5,   selectivity↑, 7,  

Clinical Biomarkers(tgid=22) ⓘ

BRCA1↑, 1,   EGFR↓, 3,   EZH2↓, 2,   GutMicro↑, 2,   hTERT/TERT↓, 1,   IL6↓, 3,   Myc↓, 1,   PD-L1↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 43,   antiNeop↑, 2,   AntiTum↑, 2,   chemoP↑, 3,   ChemoSideEff↓, 1,   radioP↑, 1,   RenoP↑, 1,   Risk↓, 1,   toxicity↓, 3,   toxicity↝, 1,   TumVol↓, 2,   TumW↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

CD8+↑, 1,  
Total Targets: 250

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

12-HETE↓, 1,   5-HETE↓, 1,   AntiArt↑, 1,   AntiBio↑, 6,   antiD↓, 1,   Eic↓, 1,   Stroke↓, 4,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 13,   Catalase↑, 5,   GPx↑, 4,   GSH↑, 3,   GSR↑, 1,   GSTs↑, 2,   H2O2↓, 1,   HO-1↑, 1,   Keap1↓, 1,   lipid-P↓, 1,   MDA↓, 2,   MDA↑, 1,   NRF2↓, 1,   NRF2↑, 2,   ROS↓, 8,   SOD↑, 5,   TBARS↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 2,   ALAT∅, 1,   BUN↓, 2,   NADPH↑, 1,  

Cell Death(tgid=5) ⓘ

BAX↓, 1,   Bcl-2↑, 1,   Casp3↓, 1,   Casp9↓, 1,   iNOS↓, 1,   MAPK↓, 1,   survivin↓, 1,   TUNEL↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   HATs↓, 1,   other↝, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

HSP70/HSPA5↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

EMT↓, 1,   GH↑, 1,   p‑mTOR↓, 1,  

Migration(tgid=13) ⓘ

APP↓, 1,   Ca+2↓, 1,   COL1↓, 1,   E-cadherin↑, 1,   PAI-1/SERPINE1↓, 1,   Vim↓, 1,   α-SMA↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 1,   NO↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   IL1?, 1,   IL1β↓, 2,   IL6?, 1,   IL6↓, 1,   Imm↑, 1,   Imm⇅, 1,   Inflam↓, 19,   LPS↓, 1,   NF-kB↓, 2,   NF-kB↑, 1,   NK cell↑, 1,   PGE2↓, 1,   PGE2↑, 1,   TLR4↓, 1,   TNF-α↓, 2,   TNF-α↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 2,   BChE↓, 1,   p‑tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,   XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

BNP↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 4,   BioAv↝, 2,   Dose↝, 1,   eff↑, 2,   eff↝, 1,   Half-Life↓, 1,   Half-Life↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   ALAT∅, 1,   AST↓, 2,   AST∅, 1,   BMD↑, 1,   BP↓, 2,   creat↓, 1,   IL6?, 1,   IL6↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↑, 7,   AntiDiabetic↑, 4,   cardioP↑, 5,   chemoP↑, 1,   cognitive↑, 2,   hepatoP↑, 4,   memory↑, 1,   neuroP?, 1,   neuroP↑, 11,   OS↑, 1,   RenoP↑, 1,   Sleep↑, 1,   toxicity↓, 8,   toxicity↑, 2,   toxicity↝, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↓, 1,   AntiFungal↑, 1,   AntiViral↑, 5,   Bacteria↓, 6,   Diar↓, 1,   Sepsis↓, 1,  
Total Targets: 120

Scientific Paper Hit Count for: AntiCan, Anticancer Effect
18 Silver-NanoParticles
12 Lycopene
10 Thymoquinone
10 Selenium NanoParticles
9 Emodin
9 Inositol
9 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
8 Capsaicin
8 Magnolol
7 Allicin (mainly Garlic)
7 Curcumin
7 Gambogic Acid
7 Kaempferol
7 Phenethyl isothiocyanate
7 Quercetin
7 Sulforaphane (mainly Broccoli)
6 Vitamin C (Ascorbic Acid)
6 Astaxanthin
6 Baicalein
6 Eugenol
6 Honokiol
6 Isoliquiritigenin
6 Selenite (Sodium)
5 Coenzyme Q10
5 Artemisinin
5 EGCG (Epigallocatechin Gallate)
5 Lactoferrin/Talactoferrin
4 chitosan
4 Apigenin (mainly Parsley)
4 Boron
4 Carvacrol
4 Chlorogenic acid
4 Crocetin
4 Dandelion Root
4 Ferulic acid
4 Isovitexin
4 Naringin
4 Selenium
3 Cisplatin
3 Melatonin
3 Aloe anthraquinones
3 beta-glucans
3 Biochanin A
3 α-Bisabolol / Chamomile oil
3 Hydroxycinnamic-acid
3 Resveratrol
3 Spermidine
3 Carvone
3 Cynara scolymus/Globe Artichoke/Artichoke Extract
3 Cucurbitacin
3 Date Fruit Extract
3 Lemongrass Extract/Citral
3 Ellagic acid
3 flavonoids
3 Formononetin
3 Fucoidan
3 Gallic acid
3 Garcinol
3 Geraniol
3 Ginkgetin
3 HydroxyTyrosol
3 Hyperoside
3 Isobavachalcone
3 Licochalcone A
3 Propolis -bee glue
3 Pterostilbene
3 salinomycin
3 Silymarin (Milk Thistle) silibinin
3 Vitamin D3
3 Vitamin K2
2 3-bromopyruvate
2 5-fluorouracil
2 Auranofin
2 doxorubicin
2 Alpha-Lipoic-Acid
2 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
2 Anethole/trans-Anethole
2 Baicalin
2 Beta-Caryophyllene
2 Boswellia (frankincense)
2 Butyrate
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Thymol-Thymus vulgaris
2 Chlorophyllin
2 Chrysin
2 Cinnamon
2 Camptothecin
2 Dichloroacetate
2 diet Fermented Foods
2 Ginkgo biloba-EGb 761
2 Germanium Organic/Ge-132 / propagermanium (organogermanium)
2 Hydrogen Gas
2 Hibiscus sabdariffa
2 iodine
2 isoquercitrin
2 Ivermectin
2 Juglone
2 Vitexin
2 Magnetic Fields
2 Bicarbonate(Sodium)
2 Piperine
2 Rosmarinic acid
2 Rauwolfia serpentina/Indian Snakeroot
2 Shikonin
2 Ursolic acid
2 Urolithin
2 VitK3,menadione
1 1,8-Cineole
1 Astragalus
1 Citric Acid
1 Ashwagandha(Withaferin A)
1 Ascorbyl Palmitate
1 Berberine
1 Betulinic acid
1 Bromelain
1 borneol
1 Bruteridin(bergamot juice)
1 Vitamin B3,Niacin
1 Caffeic acid
1 Caffeine
1 urea
1 Celastrol
1 Centella asiatica / Gotu kola → asiaticoside
1 chaetocin
1 Carica papaya leaf extract
1 irinotecan
1 Calorie Restriction Mimetics
1 Aspirin
1 Polyphenols
1 Diclofenac
1 diet FMD Fasting Mimicking Diet
1 diet Methionine-Restricted Diet
1 diet Plant based
1 Electrical Pulses
1 Eurycomanone
1 Evodiamine
1 ferumoxytol
1 Fisetin
1 Paclitaxel/Taxol
1 Gamma-aminobutyric acid
1 Ginkgo biloba
1 Geldanamycin
1 Genistein (soy isoflavone)
1 Ginger/6-Shogaol/Gingerol
1 γ-linolenic acid (Borage Oil)
1 alpha Linolenic acid
1 Graviola
1 Grapeseed extract
1 Germacranolide sesquiterpene lactone
1 Chemotherapy
1 High-Ozonide Oil
1 Hops (Humulus lupulus)
1 Indole-3-carbinol
1 isoorientin
1 itraconazole
1 Laetrile B17 Amygdalin
1 lambertianic acid
1 Licorice
1 Lecithin
1 Luteolin
1 Methylene blue
1 Photodynamic Therapy
1 Mung Bean Sprouts
1 mebendazole
1 Metformin
1 Magnetic Field Rotating
1 Methylglyoxal
1 Nimbolide
1 Oleocanthal
1 Oregano
1 Piperlongumine
1 Psoralidin
1 Parthenolide
1 Gold NanoParticles
1 Salvia officinalis
1 Radiotherapy/Radiation
1 α-Santalol/Sandalwood oil
1 Calcium
1 Aflavin-3,3′-digallate
1 Magnesium
1 Zerumbone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:813  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page