Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
1852- dietFMD,  Chemo,    Starvation Based Differential Chemotherapy: 
A Novel Approach for Cancer Treatment
- Review, Var, NA
ChemoSideEff↓, *toxicity↓, mTOR↓, IGF-1↓, IGFBP1↑, BG↓, ROS↑,
1846- dietFMD,  VitC,    A fasting-mimicking diet and vitamin C: turning anti-aging strategies against cancer
- Study, Var, NA
TumCG↓, ChemoSen↑, ChemoSideEff↓, ROS↑, Fenton↑, H2O2↑, eff↑, HO-1↓, DNAdam↑, eff↑,
1853- dietFMD,    Impact of Fasting on Patients With Cancer: An Integrative Review
- Review, Var, NA
*toxicity∅, QoL∅, eff↑, eff↝, ChemoSideEff↓, TumCG↓, Dose↑, toxicity↝, eff↑, IGF-1↑, *OXPHOS↑, BG↓, Insulin↓, RadioS↑,
1854- dietFMD,    How Far Are We from Prescribing Fasting as Anticancer Medicine?
- Review, Var, NA
ChemoSideEff↓, ChemoSen↑, IGF-1↓, IGFBP1↑, adiP↑, glyC↓, E-cadherin↑, MMPs↓, Casp3↑, ROS↑, ATP↓, AMPK↑, mTOR↓, ROS↑, Glycolysis↓, NADPH↓, OXPHOS↝, eff↑, eff↑, *RAS↓, *MAPK↓, *PI3K↓, *Akt↓, eff↑, ROS↑, Akt↑, Casp3↑,
1855- dietFMD,    Impact of modified short-term fasting and its combination with a fasting supportive diet during chemotherapy on the incidence and severity of chemotherapy-induced toxicities in cancer patients - a controlled cross-over pilot study
- Trial, NA, NA
ChemoSideEff↓, QoL↑, IGF-1↓, Insulin↓,
1857- dietFMD,    Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy
- in-vitro, BC, 4T1 - in-vivo, NA, NA
TumCG↓, ChemoSen↑, OS↑,
1858- dietFMD,  Chemo,    Effect of short-term fasting on the cisplatin activity in human oral squamous cell carcinoma cell line HN5 and chemotherapy side effects
- in-vitro, HNSCC, HN5
Apoptosis↑, necrosis↑,
1859- dietFMD,  Chemo,    Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity
- in-vitro, BC, 4T1 - in-vivo, Melanoma, B16-BL6
CLP↑, CD8+↑, TumCG↓, HO-1↓, TILs↑,
1860- dietFMD,  Chemo,    Fasting-mimicking diet blocks triple-negative breast cancer and cancer stem cell escape
- in-vitro, BC, SUM159 - in-vitro, BC, 4T1
PI3K↑, Akt↑, mTOR↑, CDK4↑, CDK6↑, hyperG↓, TumCG↓, TumVol↓, Casp3↑, BG↓, eff↑, eff∅, PKA↓, KLF5↓, p‑GSK‐3β↑, Nanog↓, OCT4↓, KLF2↓, eff↑, ROS↑, BIM↑, ASK1↑, PI3K↑, Akt↑, mTOR↑, CDK1↓, CDK4↑, CDK6↑, eff↑,
1861- dietFMD,  Chemo,    Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models
- in-vitro, Colon, CT26 - in-vivo, NA, NA
selectivity↑, ChemoSen↑, BG↓, AminoA↓, Warburg↓, OCR↑, ATP↓, ROS↑, Apoptosis↑, GlucoseCon↓, PI3K↓, PTEN↑, GLUT1↓, GLUT2↓, HK2↓, PFK1↓, PKA↓, ATP:AMP↓, Glycolysis↓, lactateProd↓,
1862- dietFMD,    Exceptional tumour responses to fasting-mimicking diet combined with standard anticancer therapies: A sub-analysis of the NCT03340935 trial
- Trial, Var, NA
OS↑,
1843- dietFMD,  BTZ,    Cyclic Fasting–Mimicking Diet Plus Bortezomib and Rituximab Is an Effective Treatment for Chronic Lymphocytic Leukemia
- in-vivo, CLL, NA
AntiTum↓, Apoptosis↑, IGF-1↓, eff↑, OS↑, eff↑,
1842- dietFMD,    Safety and Feasibility of Fasting-Mimicking Diet and Effects on Nutritional Status and Circulating Metabolic and Inflammatory Factors in Cancer Patients Undergoing Active Treatment
- Trial, Var, NA
Strength∅, Weight∅, IGF-1↓, IGFBP3↑, IGFBP1↑, eff↑,
1841- dietFMD,    Fasting-Mimicking Diet Is Safe and Reshapes Metabolism and Antitumor Immunity in Patients with Cancer
- Trial, Var, NA
BG↓, AntiCan↑, IFN-γ↑, eff↑, Dose↝, CD14↓, IGF-1↓, IGFR↓, CD8+↑, NK cell↑,
5067- dietFMD,    Fasting-mimicking diet potentiates anti-tumor effects of CDK4/6 inhibitors against breast cancer by suppressing NRAS- and IGF1-mediated mTORC1 signaling
- in-vitro, BC, NA
mTORC1↓, IGF-1↓, RAS↓,
1810- dietKeto,  Oxy,    The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice with Systemic Metastatic Cancer
- in-vivo, Var, NA
BG↓, TumCG↓, OS↑, eff↑, Dose∅, KeyT↑, eff↑, cachexia↓, ChemoSen↑, *ROS↓, ROS↑, lipid-P↑, selectivity↑, toxicity∅,
4256- dietMed,    Association between Mediterranean dietary pattern with sleep duration, sleep quality and brain derived neurotrophic factor (BDNF) in Iranian adults
- Study, Nor, NA
*Sleep↑, *BDNF↑,
1897- dietMet,    Methionine metabolism in health and cancer: a nexus of diet and precision medicine
- Review, Var, NA
OS↑, TumCG↓, TumCCA↑, ChemoSen↑, RadioS↑,
1896- dietMet,    Dietary methionine links nutrition and metabolism to the efficacy of cancer therapies
- in-vivo, CRC, NA
TumCG↓, *GSH↓, RadioS↑, eff↑,
1895- dietMet,    Altering Diet Enhances Response to Cancer Treatments in Mice
- Review, Var, NA
ChemoSen↑,
1894- dietMet,    Long term methionine restriction: Influence on gut microbiome and metabolic characteristics
- in-vivo, Nor, NA
*GutMicro↓, *OS↑, Weight↓, BG↓,
1893- dietMet,    Clinical Studies of Methionine-Restricted Diets for Cancer Patients
- Review, Var, NA
TumCG↓, ChemoSen↑, MATs↓,
2170- dietMet,    Low Protein Intake is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population
- Study, Var, NA
OS↑, eff↝, other↝,
2273- dietMet,    Methionine and cystine double deprivation stress suppresses glioma proliferation via inducing ROS/autophagy
- in-vitro, GBM, U87MG - in-vitro, GBM, U251 - in-vivo, NA, NA
ROS↑, GSH↓, TumCP↓, TumAuto↑, LC3II↑,
2272- dietMet,    Methionine restriction - Association with redox homeostasis and implications on aging and diseases
- Review, Nor, NA
*OS↑, *mt-ROS↓, *H2S↑, *FGF21↑, *cognitive↑, *GutMicro↑, *IGF-1↓, *mTOR↓, *GSH↑, *SOD↑, *MDA↓, *NRF2↑, *HO-1↑, *NQO1↑, *GLUT4↑, *Glycolysis↑, *HK2↑, *PFK↑, *PKM2↑, *GlucoseCon↑, *ATF4↑, *PPARα↑, GSH↓, GSTs↑, ROS↑, *neuroP↑,
2271- dietMet,    A review of methionine dependency and the role of methionine restriction in cancer growth control and life-span extension
- Review, Nor, NA
*eff↑, *OS↓, *ROS↓, *Weight↓,
2269- dietMet,    Mechanisms of Increased In Vivo Insulin Sensitivity by Dietary Methionine Restriction in Mice
- in-vivo, Nor, NA
*adiP↑, *FGF↑, *Insulin↓, *glucose↓, *Akt↑, *GSH↓, *PTEN↓, *FGF21↑, *PIP3↑,
2268- dietMet,    Methionine dependency and cancer treatment
- Review, Var, NA
ChemoSen↑, *eff↑, selectivity↑, eff↑,
2263- dietMet,    Methionine Restriction and Cancer Biology
- Review, Var, NA
AntiCan↑, TumCP↓, TumCG↓, selectivity↑, ChemoSen↓, RadioS↑, Insulin↓, *GlucoseCon↑, *ROS↓, *antiOx↑, *GSH↑, GSH↑, eff↑, polyA↓, TS↓, Raf↓, Akt↓, Casp9↑, Bak↑, P21↑, p27↑, Insulin↓, IGF-1↓,
2264- dietMet,    Methionine restriction for cancer therapy: From preclinical studies to clinical trials
- Review, Var, NA
TumCP↓, *ROS?, ChemoSen↑, RadioS↑, eff↑, ROS↑, selectivity↑, TS↓, eff↑,
2265- dietMet,    Cysteine supplementation reverses methionine restriction effects on rat adiposity: significance of stearoyl-coenzyme A desaturase
- in-vivo, Nor, NA
*SCD1↓, *Weight↓, *Insulin↓, *IGF-1↓, *adiP↑, *eff↓,
2266- dietMet,    Cysteine dietary supplementation reverses the decrease in mitochondrial ROS production at complex I induced by methionine restriction
- in-vivo, Nor, NA
*ROS↓, eff↓,
2267- dietMet,    Role of amino acids in regulation of ROS balance in cancer
- Review, Var, NA
TumCG↓, GSH↓, ROS↑,
2270- dietMet,    Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cycle inhibitors in athymic nude mice
- in-vivo, Var, NA
Weight↓, TumVol↓, P21↑, p27↑, *adiP↑, *glucose↓, *IGF-1↓, *FGF21↑, *OS↑, Ki-67↓, Casp3↑, cycD1/CCND1↓,
5188- dietMet,    Dietary methionine links nutrition and metabolism to the efficacy of cancer therapies
- in-vivo, Var, NA
AntiAge↑, MethCyc↓, TumCG↓, ChemoSen↑, RadioS↑, OS↑, GSH↓,
5193- dietMet,  Rad,    A Phase I Trial of a Methionine Restricted Diet with Concurrent Radiation Therapy
- Trial, Var, NA
toxicity↝, other↝,
5192- dietMet,    Intermittent methionine restriction reduces IGF‐1 levels and produces similar healthspan benefits to continuous methionine restriction
OS↑, eff↝, IGF-1↓, adiP↑, Leptin↓, Weight↓,
5191- dietMet,    Intermittent dietary methionine deprivation facilitates tumoral ferroptosis and synergizes with checkpoint blockade
- in-vitro, Colon, HT29
ChemoSen↑, RadioS↑, Ferroptosis↑, eff↑, eff↑, GSH↓, eff↓,
5190- dietMet,    Methionine restriction activates the integrated stress response in triple-negative breast cancer cells by a GCN2- and PERK-independent mechanism
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-468
p‑eIF2α↑, ATF4↑, SESN2↑, TumCCA↑, Apoptosis↑, other↑,
5189- dietMet,    Mechanism of Activation of Mechanistic Target of Rapamycin Complex 1 by Methionine
- Review, Var, NA
OS↑, mTORC1↓, TumAuto↑,
2161- dietP,    Plant-Based Diets and Cancer Prognosis: a Review of Recent Research
- Review, NA, NA
OS↑, eff↑, eff↑,
2165- dietP,  SFN,    Broccoli sprout supplementation in patients with advanced pancreatic cancer is difficult despite positive effects—results from the POUDER pilot study
- Trial, PC, NA
Dose↝, OS↑, eff↝,
2163- dietP,  SFN,    Intake of Cruciferous Vegetables Modifies Bladder Cancer Survival
- Human, Bladder, NA
OS↑, OS∅,
2162- dietP,    Effect of low-fat diet on breast cancer survival: a meta-analysis
- Analysis, BC, NA
Risk↓, OS↑,
2160- dietP,    Dietary proteins and protein sources and risk of death: the Kuopio Ischaemic Heart Disease Risk Factor Study
- Trial, Heart, NA
Risk↓,
2159- dietP,    Postdiagnostic Fruit and Vegetable Consumption and Breast Cancer Survival: Prospective Analyses in the Nurses' Health Studies
- Human, BC, NA
Risk↑, Risk∅, OS↑, OS↓,
2158- dietP,    Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality in a Japanese Cohort
- Human, Nor, NA
OS↓, Risk↓,
2157- dietP,    Plant-Based Diets and Disease Progression in Men With Prostate Cancer
- Study, Pca, NA
TumCG↓, Risk↓, eff↑,
2156- dietP,    Phytochemical-rich vegetable and fruit juice alleviates oral mucositis during concurrent chemoradiotherapy in patients with locally advanced head and neck cancer
- Human, HNSCC, NA
chemoP↑, radioP↑, eff↑,
2155- dietP,    Transepithelial Anti-Neuroblastoma Response to Kale among Four Vegetable Juices Using In Vitro Model Co-Culture System
- in-vivo, neuroblastoma, Caco-2 - NA, NA, SH-SY5Y
AntiCan↑, ROS↑, eff↑, eff↑, eff↑,

Showing Research Papers: 2601 to 2650 of 6149
Prev Page 53 of 123 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 6149

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Fenton↑, 1,   Ferroptosis↑, 1,   GSH↓, 5,   GSH↑, 1,   GSTs↑, 1,   H2O2↑, 1,   HO-1↓, 2,   hyperG↓, 1,   lipid-P↑, 1,   OXPHOS↝, 1,   ROS↑, 13,  

Metal & Cofactor Biology ⓘ

KLF5↓, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↓, 2,   Insulin↓, 4,   OCR↑, 1,   Raf↓, 1,  

Core Metabolism/Glycolysis ⓘ

adiP↑, 2,   AminoA↓, 1,   AMPK↑, 1,   ATP:AMP↓, 1,   GlucoseCon↓, 1,   GLUT2↓, 1,   glyC↓, 1,   Glycolysis↓, 2,   HK2↓, 1,   KeyT↑, 1,   lactateProd↓, 1,   MATs↓, 1,   MethCyc↓, 1,   NADPH↓, 1,   PFK1↓, 1,   polyA↓, 1,   TS↓, 2,   Warburg↓, 1,  

Cell Death ⓘ

Akt↓, 1,   Akt↑, 3,   Apoptosis↑, 4,   ASK1↑, 1,   Bak↑, 1,   BIM↑, 1,   Casp3↑, 4,   Casp9↑, 1,   Ferroptosis↑, 1,   necrosis↑, 1,   p27↑, 2,  

Transcription & Epigenetics ⓘ

other↑, 1,   other↝, 2,  

Protein Folding & ER Stress ⓘ

p‑eIF2α↑, 1,  

Autophagy & Lysosomes ⓘ

LC3II↑, 1,   SESN2↑, 1,   TumAuto↑, 2,  

DNA Damage & Repair ⓘ

DNAdam↑, 1,  

Cell Cycle & Senescence ⓘ

CDK1↓, 1,   CDK4↑, 2,   cycD1/CCND1↓, 1,   P21↑, 2,   TumCCA↑, 2,  

Proliferation, Differentiation & Cell State ⓘ

p‑GSK‐3β↑, 1,   IGF-1↓, 9,   IGF-1↑, 1,   IGFBP1↑, 3,   IGFBP3↑, 1,   IGFR↓, 1,   mTOR↓, 2,   mTOR↑, 2,   mTORC1↓, 2,   Nanog↓, 1,   OCT4↓, 1,   PI3K↓, 1,   PI3K↑, 2,   PTEN↑, 1,   RAS↓, 1,   TumCG↓, 13,  

Migration ⓘ

E-cadherin↑, 1,   Ki-67↓, 1,   KLF2↓, 1,   MMPs↓, 1,   PKA↓, 2,   TumCP↓, 3,  

Angiogenesis & Vasculature ⓘ

ATF4↑, 1,  

Barriers & Transport ⓘ

GLUT1↓, 1,  

Immune & Inflammatory Signaling ⓘ

CD14↓, 1,   CLP↑, 1,   IFN-γ↑, 1,   NK cell↑, 1,   TILs↑, 1,  

Hormonal & Nuclear Receptors ⓘ

CDK6↑, 2,   Leptin↓, 1,  

Drug Metabolism & Resistance ⓘ

ChemoSen↓, 1,   ChemoSen↑, 12,   Dose↑, 1,   Dose↝, 2,   Dose∅, 1,   eff↓, 2,   eff↑, 30,   eff↝, 4,   eff∅, 1,   RadioS↑, 7,   selectivity↑, 5,  

Clinical Biomarkers ⓘ

BG↓, 7,   Ki-67↓, 1,  

Functional Outcomes ⓘ

AntiAge↑, 1,   AntiCan↑, 3,   AntiTum↓, 1,   cachexia↓, 1,   chemoP↑, 1,   ChemoSideEff↓, 5,   OS↓, 2,   OS↑, 14,   OS∅, 1,   QoL↑, 1,   QoL∅, 1,   radioP↑, 1,   Risk↓, 4,   Risk↑, 1,   Risk∅, 1,   Strength∅, 1,   toxicity↝, 2,   toxicity∅, 1,   TumVol↓, 2,   Weight↓, 3,   Weight∅, 1,  

Infection & Microbiome ⓘ

CD8+↑, 2,  
Total Targets: 123

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,   GSH↓, 2,   GSH↑, 2,   HO-1↑, 1,   MDA↓, 1,   NQO1↑, 1,   NRF2↑, 1,   OXPHOS↑, 1,   ROS?, 1,   ROS↓, 4,   mt-ROS↓, 1,   SOD↑, 1,  

Mitochondria & Bioenergetics ⓘ

Insulin↓, 2,  

Core Metabolism/Glycolysis ⓘ

adiP↑, 3,   FGF21↑, 3,   glucose↓, 2,   GlucoseCon↑, 2,   Glycolysis↑, 1,   H2S↑, 1,   HK2↑, 1,   PFK↑, 1,   PIP3↑, 1,   PKM2↑, 1,   PPARα↑, 1,   SCD1↓, 1,  

Cell Death ⓘ

Akt↓, 1,   Akt↑, 1,   MAPK↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

FGF↑, 1,   IGF-1↓, 3,   mTOR↓, 1,   PI3K↓, 1,   PTEN↓, 1,   RAS↓, 1,  

Angiogenesis & Vasculature ⓘ

ATF4↑, 1,  

Barriers & Transport ⓘ

GLUT4↑, 1,  

Synaptic & Neurotransmission ⓘ

BDNF↑, 1,  

Drug Metabolism & Resistance ⓘ

eff↓, 1,   eff↑, 2,  

Clinical Biomarkers ⓘ

GutMicro↓, 1,   GutMicro↑, 1,  

Functional Outcomes ⓘ

cognitive↑, 1,   neuroP↑, 1,   OS↓, 1,   OS↑, 3,   Sleep↑, 1,   toxicity↓, 1,   toxicity∅, 1,   Weight↓, 2,  
Total Targets: 49

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
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