Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
7480- Hup,    Pharmacokinetics of huperzine A following oral administration to human volunteers
- Trial, AD, NA
*Dose↝, *BioAv↝, *Half-Life↝,
7602- I3C,    Dose-ranging study of indole-3-carbinol for breast cancer prevention
- Trial, BC, NA
toxicity↓, Dose↝, 2/16-OHE1↑, chemoPv↑,
7611- I3C,    Long-term responses of women to indole-3-carbinol or a high fiber diet
- Trial, Nor, NA
*Dose↝, *2/16-OHE1↑,
7580- I3C,    Single-dose and multiple-dose administration of indole-3-carbinol to women: pharmacokinetics based on 3,3'-diindolylmethane
- Trial, NA, NA
Dose↝, BioAv↝, Dose↝,
7581- I3C,    A phase I study of indole-3-carbinol in women: tolerability and effects
- Trial, Nor, NA
CYP1A2↑, Dose↝,
7578- IMA,    Long-Term Outcomes of Imatinib Treatment for Chronic Myeloid Leukemia
- Trial, CML, NA
OS↑, toxicity↓, BCR-ABL↓,
7579- IMA,    One vs three years of adjuvant imatinib for operable gastrointestinal stromal tumor: a randomized trial
- Trial, GC, NA
RFS↑, OS↑,
7616- Ins,    A phase I study of myo-inositol for lung cancer chemoprevention
- Trial, Nor, NA
*Dose↝, *toxicity↝, *BP↓,
7634- Ins,    Risk of reduced intestinal absorption of myo-inositol caused by D-chiro-inositol or by glucose transporter inhibitors
- Trial, Nor, NA
*BioAv↓,
7643- Ins,  IP6,    Efficacy of IP6 + inositol in the treatment of breast cancer patients receiving chemotherapy: prospective, randomized, pilot clinical stud
- Trial, BC, NA
RBC↑, QoL↑, eff↑, Imm↑, ChemoSen↑, chemoP↑, Dose↝,
7633- Ins,    Myo-inositol in a new pharmaceutical form: a step forward to a broader clinical use
- Trial, Nor, NA
*BioAv↑, *toxicity↓,
7673- iod,  Chemo,    Adjuvant Effect of Molecular Iodine in Conventional Chemotherapy for Breast Cancer. Randomized Pilot Study
- Trial, BC, NA
Dose↝, *chemoP↑,
7672- iod,    Adjuvant Effect of Molecular Iodine in Conventional Chemotherapy for Breast Cancer. Randomized Pilot Study
- Trial, BC, NA
Dose↝, OS↑, TumCI↓, Apoptosis↑, EstroRS/ERS↑, eff↑, *cardioP↑, *antiOx↑, *Inflam↓,
7684- iod,    Molecular iodine impairs chemotherapy resistance and adverse effects in breast cancer treatments
- Trial, BC, NA
Dose↝, OS↑, antiNeop↑, eff↑,
7661- IP,    Enhancement of carbohydrate metabolism by probiotic and prebiotic intake promotes short-chain fatty acid production in the gut microbiome: a randomized, double-blind, placebo-controlled crossover trial
- Trial, Nor, NA
*PA↑, *Buty↑, *GutMicro↑, *SCFAs↑,
7662- IP,    Digestive tolerance of inulin-type fructans: a double-blind, placebo-controlled, cross-over, dose-ranging, randomized study in healthy volunteers
- Trial, Nor, NA
Dose↝, toxicity↓,
7664- IP,  GCL2505,    Administration of bifidobacteria and dietary fiber improves cognitive function by increasing short-chain fatty acid-producing bacteria and reducing inflammation
- Trial, AD, NA
*cognitive↑, *SCFAs↑, *GutMicro↑, *Buty↑, *AcOH↑, *neuroP↑,
7665- IP,    A Prebiotic-Supplemented Formula Improves Gut Microbiota and Intestinal Inflammatory Microenvironment in Patients with Colorectal Adenoma: A Double-Blind, Placebo-Controlled Trial
- Trial, Nor, NA
*GutMicro↑, *Inflam↓,
7666- IP,    Short-chain fatty acid kinetics and concentrations are higher after inulin supplementation in young and older adults: a randomized trial
- Trial, Nor, NA
*Dose↝, *Buty↑, *PA↑, *AcOH↑, *SCFAs↑,
7668- IP,    A phase 2 randomized, placebo-controlled trial of inulin for the prevention of gut pathogen colonization and infection among patients admitted to the intensive care unit for sepsis
- Trial, Sepsis, NA
*Dose↝, *SCFAs∅, *GutMicro∅, *other↝,
7640- IP6,  Ins,    Effects of Inositol Hexaphosphate and Myo-Inositol Administration in Breast Cancer Patients during Adjuvant Chemotherapy
- Trial, BC, NA
*antiOx↑, QoL↑, RBC↑, HemoG↑, WBC↑, chemoP↑, Dose↝,
7741- isoFl,  Lyco,  SIL,    Randomized, double-blind, placebo-controlled crossover study in men with prostate cancer and rising PSA: effectiveness of a dietary supplement
- Trial, Pca, NA
Dose↝, PSA↓,
7740- isoFl,    Effect of soy protein isolate supplementation on biochemical recurrence of prostate cancer after radical prostatectomy: a randomized trial
- Trial, Pca, NA
Dose↝, Risk∅,
7738- isoFl,    Consumption of soy isoflavone enriched bread in men with prostate cancer is associated with reduced pro-inflammatory cytokines and immune suppressive cells
- Trial, Pca, NA
Dose↝, CD4+↓, CD25+↓, FoxP3+↓, other↓, Inflam↓, CSCs↓, other↝,
7731- isoFl,    Long-term soy isoflavone supplementation and cognition in women: a randomized, controlled trial
- Trial, AD, NA
*cognitive∅, *memory↑,
7850- ISQ,    Effect of quercetin glycosides on cognitive functions and cerebral blood flow: a randomized, double-blind, and placebo-controlled study
- Trial, Nor, NA
*Dose↝, *RT↓, *BloodF↑, *Aβ↓,
7996- itraC,    Itraconazole in the Treatment of Aberrantly Active Hedgehog and/or PI3K Recurrent Ovarian Cancer
- Trial, Ovarian, NA
HH↓, PI3K↓, toxicity↝, eff∅, CA125∅, other↝,
7991- itraC,    A Phase II Trial of Perioperative Oral Itraconazole for the Management of Low-Risk Basal Cell Carcinoma
- Trial, BCC, NA
Smo↓, Dose↓, TumVol↓, Endoglin↓, angioG↓, toxicity↝, GLI3↓, toxicity↓,
7990- itraC,    A Novel Approach to Reducing Chemoresistance in Advanced Ovarian Cancer: The Effect of Itraconazole-A Single-Institution Randomized Placebo-Controlled Trial
- Trial, Ovarian, NA
Dose↝, DCR↑, PFS↑, CA125↓, P-gp/ABCB1↓, VEGFR2/KDR/Flk1↑, toxicity↓, QoL↑, toxicity↝,
7989- itraC,    Concentration-dependent Early Antivascular and Antitumor Effects of Itraconazole in Non-Small Cell Lung Cancer
- Trial, NSCLC, NA
Dose↝, TumVol↓, angioG↓, IL1β↓, GM-CSF↓, HH∅, BioAv↝, other↝,
7988- itraC,    Itraconazole as a Noncastrating Treatment for Biochemically Recurrent Prostate Cancer: A Phase 2 Study
- Trial, Pca, NA
PSA↓, toxicity↝, testos∅, toxicity↝,
7987- itraC,    Repurposing itraconazole as a treatment for advanced prostate cancer: a noncomparative randomized phase II trial in men with metastatic castration-resistant prostate cancer
- Trial, Pca, NA
angioG↓, HH↓, Dose↝, PSA↓, CTC↓, other↝, toxicity↝,
7986- itraC,    Open-label, exploratory phase II trial of oral itraconazole for the treatment of basal cell carcinoma
- Trial, BCC, NA
Dose↝, TumCP↓, HH↓, TumVol↓, SD↑,
8018- itraC,  Chemo,    Impact of combination chemotherapy with itraconazole on survival of patients with refractory ovarian cancer
- Trial, Ovarian, NA
PFS↑, OS↑, other↝,
8058- KAE,    A randomized, placebo‐controlled trial evaluating the safety of excessive administration of kaempferol aglycone
- Trial, Nor, NA
*AntiBio↑, *antiOx↑, *Inflam↓, *AntiTum↑, *AntiDiabetic↑, *cardioP↑, *neuroP↑, *Dose↝, *toxicity↓,
8109- L-Orn,    Effects of Oral Ingestion of L-Ornithine on Mental Stress and Fatigue Based on the Trier Social Stress Test in Healthy Humans: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Trial
- Trial, Nor, NA
*cortisol↓, *Stress↓, *Dose↝, *fatigue↓,
8110- L-Orn,    L-ornithine supplementation attenuates physical fatigue in healthy volunteers by modulating lipid and amino acid metabolism
- Trial, Nor, NA
*Dose↝, *KeyT↝, *FFA/NEFA↝, *NH3↓, *fatigue↓,
8119- LA,    Perioperative synbiotics administration decreases postoperative infections in patients with colorectal cancer: a randomized, double-blind clinical trial
- Trial, CRC, NA
Inf↓, Inf↓,
8117- LA,  ProBio,    The effects of perioperative probiotic treatment on serum zonulin concentration and subsequent postoperative infectious complications after colorectal cancer surgery: a double-center and double-blind randomized clinical trial
- Trial, CRC, NA
Dose↝, Inf↓, ZO-1↓, other↓,
8118- LA,  ProBio,    Randomised clinical trial: the effects of perioperative probiotic treatment on barrier function and post-operative infectious complications in colorectal cancer surgery - a double-blind study
- Trial, CRC, NA
Inf↓, IBI↑, Dose↝, Diar↓,
1272- LA,    Lactobacillus johnsonii N6.2 Modulates the Host Immune Responses: A Double-Blind, Randomized Trial in Healthy Adults
- Trial, Nor, NA
*Pain↓, *other↑,
8158- lamb,    Effect of Pinus koraiensis leaf extract on fatigue reduction and exercise performance: study protocol for a randomized, double-blind, placebo-controlled clinical trial
- Trial, Nor, NA
*Strength↑, *lactateProd↓, *LDH↓, *CK2↓,
8172- Lap,    Administration of Lapatinib with Food Increases Its Plasma Concentration in Chinese Patients with Metastatic Breast Cancer: A Prospective Phase II Study
- Trial, BC, NA
BioAv↑, eff↑,
8171- Lap,    Effects of food on the relative bioavailability of lapatinib in cancer patients
- Trial, Var, NA
BioAv↝, Dose↝,
8170- Lap,  capec,    A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses
- Trial, BC, NA
Dose↝, TTP↑, OS↑,
8123- LF,    Effect of orally administered bovine lactoferrin on the growth of adenomatous colorectal polyps in a randomized, placebo-controlled clinical trial
- Trial, CRC, NA
AntiCan↑, Dose↝, APG↓,
8124- LF,    Inhibition of intestinal polyp growth by oral ingestion of bovine lactoferrin and immune cells in the large intestine
- Trial, CRC, NA
Risk↓, Dose↝, NK cell↑, Neut↑, CD4+↑, Imm↑, APG↓,
8125- LF,    Talactoferrin alfa versus placebo in patients with refractory advanced non-small-cell lung cancer (FORTIS-M trial)
- Trial, NSCLC, NA
Dose?, eff∅,
8127- LF,    Phase I trial of oral talactoferrin alfa in refractory solid tumors
- Trial, Var, NA
Imm↑, NK cell↑, Dose↝, toxicity↓, IL18↑, SD↑, TumCG↓, OS↑,
8128- LF,    Phase 2 trial of talactoferrin in previously treated patients with metastatic renal cell carcinoma
- Trial, RCC, NA
Imm↑, NK cell↑, Dose↝, toxicity↓, PFS↑,

Showing Research Papers: 251 to 300 of 398
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 398

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0)

2/16-OHE1↑, 1,   APG↓, 2,   DCR↑, 1,   PFS↑, 3,   RBC↑, 2,   RFS↑, 1,   TTP↑, 1,   WBC↑, 1,  

Mitochondria & Bioenergetics(tgid=3)

BCR-ABL↓, 1,  

Cell Death(tgid=5)

Apoptosis↑, 1,  

Transcription & Epigenetics(tgid=7)

other↓, 2,   other↝, 5,   SD↑, 2,  

Proliferation, Differentiation & Cell State(tgid=12)

CSCs↓, 1,   HH↓, 3,   HH∅, 1,   PI3K↓, 1,   Smo↓, 1,   TumCG↓, 1,  

Migration(tgid=13)

GLI3↓, 1,   TumCI↓, 1,   TumCP↓, 1,   ZO-1↓, 1,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 3,   Endoglin↓, 1,   VEGFR2/KDR/Flk1↑, 1,  

Barriers & Transport(tgid=15)

IBI↑, 1,   P-gp/ABCB1↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

CD25+↓, 1,   CD4+↓, 1,   CD4+↑, 1,   FoxP3+↓, 1,   GM-CSF↓, 1,   IL18↑, 1,   IL1β↓, 1,   Imm↑, 4,   Inflam↓, 1,   Neut↑, 1,   NK cell↑, 3,   PSA↓, 3,  

Hormonal & Nuclear Receptors(tgid=20)

EstroRS/ERS↑, 1,   testos∅, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↑, 1,   BioAv↝, 3,   ChemoSen↑, 1,   CYP1A2↑, 1,   Dose?, 1,   Dose↓, 1,   Dose↝, 25,   eff↑, 4,   eff∅, 2,  

Clinical Biomarkers(tgid=22)

CA125↓, 1,   CA125∅, 1,   CTC↓, 1,   EstroRS/ERS↑, 1,   HemoG↑, 1,   PSA↓, 3,  

Functional Outcomes(tgid=23)

AntiCan↑, 1,   antiNeop↑, 1,   chemoP↑, 2,   chemoPv↑, 1,   OS↑, 7,   QoL↑, 3,   Risk↓, 1,   Risk∅, 1,   toxicity↓, 7,   toxicity↝, 6,   TumVol↓, 3,  

Infection & Microbiome(tgid=24)

Diar↓, 1,   Inf↓, 4,  
Total Targets: 70

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0)

2/16-OHE1↑, 1,   AcOH↑, 2,   AntiBio↑, 1,   Buty↑, 3,   FFA/NEFA↝, 1,   PA↑, 2,   RT↓, 1,   SCFAs↑, 3,   SCFAs∅, 1,   Stress↓, 1,  

Redox & Oxidative Stress(tgid=1)

antiOx↑, 3,  

Core Metabolism/Glycolysis(tgid=4)

KeyT↝, 1,   lactateProd↓, 1,   LDH↓, 1,   NH3↓, 1,  

Cell Death(tgid=5)

CK2↓, 1,  

Transcription & Epigenetics(tgid=7)

other↑, 1,   other↝, 1,  

Immune & Inflammatory Signaling(tgid=16)

Inflam↓, 3,  

Protein Aggregation(tgid=19)

Aβ↓, 1,  

Hormonal & Nuclear Receptors(tgid=20)

cortisol↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 1,   BioAv↑, 1,   BioAv↝, 1,   Dose↝, 9,   Half-Life↝, 1,  

Clinical Biomarkers(tgid=22)

BloodF↑, 1,   BP↓, 1,   GutMicro↑, 3,   GutMicro∅, 1,   LDH↓, 1,  

Functional Outcomes(tgid=23)

AntiDiabetic↑, 1,   AntiTum↑, 1,   cardioP↑, 2,   chemoP↑, 1,   cognitive↑, 1,   cognitive∅, 1,   fatigue↓, 2,   memory↑, 1,   neuroP↑, 2,   Pain↓, 1,   Strength↑, 1,   toxicity↓, 2,   toxicity↝, 1,  
Total Targets: 44

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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