AntiCan Cancer Research Results

AntiCan, Anticancer Effect: Click to Expand ⟱
Source:
Type: general indicator
Anticancer Effect


Scientific Papers found: Click to Expand⟱
7552- HYP,    Hyperoside exerts potent anticancer activity in skin cancer
- vitro+vivo, Melanoma, NA
AntiCan↑, *Inflam↓, *antiOx↑, PI3K↓, Akt↓, mTOR↓, TumCP↓, Apoptosis↑, TumAuto↑, chemoPv↑,
7609- I3C,    Molecular Targets, Anti-cancer Properties and Potency of Synthetic Indole-3-carbinol Derivatives
- Review, Var, NA
AntiCan↑, tumCV↓, HIF-1↓, NF-kB↓, IGF-1↓, PI3K↓, Akt↓, Wnt↓, EstroRS/ERS↓,
7385- IBC,    Fighting cancer by triggering non-canonical mitochondrial permeability transition-driven necrosis through reactive oxygen species induction
- vitro+vivo, Lung, A549 - in-vitro, BC, 4T1
Apoptosis↑, necrosis↑, ROS↑, mtDam↑, Ca+2↑, MPT↑, MMP↓, AntiCan↑, *AntiBio↑, *Inflam↓, *antiOx↓, *neuroP↑, p‑Akt↓, DHODH↓, Diff↑, MAPK↑,
7801- IBC,    Isobavachalcone as an Active Membrane Perturbing Agent and Inhibitor of ABCB1 Multidrug Transporter
- in-vitro, CRC, HT-29
PSEN2/PS-2↓, AntiCan↑, Apoptosis↑, Akt↓, ERK↓, *antiOx↑, *Inflam↓, *neuroP↑, *toxicity↓, selectivity↑,
7769- IBC,    Potential Determinants for Metabolic Fates and Inhibitory Effects of Isobavachalcone Involving in Human Cytochrome P450, UDP-Glucuronosyltransferase Enzymes, and Efflux Transporters
- in-vivo, NA, NA
*AntiCan↑, *AntiAg↑, *AntiFungal↑, CYP2C9↓, UGT1A↓, CYP2D6↓, CYP2E1↓,
7630- Ins,    Modulation of both Insulin Resistance and Cancer Growth by Inositol
- Review, Var, NA - Review, Diabetic, NA
*IRes↓, *AntiDiabetic↑, *glucose↝, AntiCan↑, PI3K↓, Akt↓, Glycolysis↓, STK11/LKB1↑, *FASN↓, *LDL↓, *FFA/NEFA↓, *ROS↓, ROS↑, IGF-1↓,
7629- Ins,    Reduced IL-6 levels and tumor-associated phospho-STAT3 are associated with reduced tumor development in a mouse model of lung cancer chemoprevention with myo-inositol
- in-vivo, Lung, NA
AntiCan↑, TumVol↓, PI3K↓, IL6↓, p‑STAT3↓, chemoPv↑,
7648- Ins,    Suppression of lung and liver carcinogenesis in mice by oral administration of myo-inositol
- in-vivo, Liver, NA
AntiCan↑, Dose↝, Risk↓, chemoPv↑,
7639- Ins,    Myo-Inositol Reverses TGF-β1-Induced EMT in MCF-10A Non-Tumorigenic Breast Cells
- in-vitro, Nor, MCF10
EMT↓, E-cadherin↑, AntiCan↑, MMP9↓,
7641- Ins,    Overview of Inositol and Inositol Phosphates on Chemoprevention of Colitis-Induced Carcinogenesis
- Review, CRC, NA
AntiCan↑, p‑Akt↓, TF-Ag↓, *PI3K↓, *AP-1↓, *DNArepair↑, *BioAv↑, *BBB↑, *other↑, *PGE2↓,
7632- Ins,    The paradoxical role of inositol in cancer: a consequence of the metabolic state of a tumor
- Review, Var, NA
AMPK↑, AntiCan⇅, p‑Akt↓, PI3K↓,
7677- iod,    Activation of peroxisome proliferator-activated receptor gamma is crucial for antitumoral effects of 6-iodolactone
- in-vitro, BC, MCF7
TumCP↓, 6IL↑, PPARγ↑, AntiCan↑,
7682- iod,    Molecular Iodine Induces Anti- and Pro-Neoplastic Effects in Prostate Cancer Models
- in-vitro, Pca, LNCaP - in-vitro, Pca, DU145 - in-vitro, Pca, PC3
PPARγ↑, antiNeop↑, TumCD↑, TumCI↓, AntiCan⇅, antiOx↑, Inflam↓, Apoptosis↑, tumCV↓,
7723- IP6,    Prostate cancer and inositol hexaphosphate: efficacy and mechanisms
- Review, Pca, NA
toxicity↓, AntiCan↑, TumCG↓, TumCCA↑, angioG↓,
7728- IP6,    G0/G1 arrest and S phase inhibition of human cancer cell lines by inositol hexaphosphate (IP6)
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231 - in-vitro, CRC, HT-29
AntiCan↑, TumCCA↑, Ki-67↓, PCNA↓,
7726- IP6,    Inositol hexaphosphate (IP6) blocks proliferation of human breast cancer cells through a PKCdelta-dependent increase in p27Kip1 and decrease in retinoblastoma protein (pRb) phosphorylation
- in-vitro, BC, MCF7
AntiCan↑, PKCδ↑, ERK↓, Akt↓, p27/CDKN1B↑, p‑pRB↓,
7695- IP6,    The effect of inositol hexaphosphate on the expression of selected metalloproteinases and their tissue inhibitors in IL-1β-stimulated colon cancer cells
- in-vitro, Colon, Caco-2
AntiCan↑, TumCA↓, TumCMig↓, MMP13↓, MMP3↓, MMP2↓, TIMP1↓, MMP1↓, MMP9↓, TIMP2↓,
7642- IP6,    Inositol Hexaphosphate Inhibits Proliferation and Induces Apoptosis of Colon Cancer Cells by Suppressing the AKT/mTOR Signaling Pathway
- in-vitro, CRC, NA
AntiCan↑, TumCP↓, Apoptosis↑, P21↑, p27/CDKN1B↑, Casp3↑, Casp9↑, AKT1↓, S6K↓, mTOR↓,
7645- IP6,  Ins,    Anticancer Properties of Inositol Hexaphosphate and Inositol: An Overview
AntiCan↑, TumCP↓, Apoptosis↑, Diff↑, p27/CDKN1B↓, pRB↓, PI3K↓, RAS↓, ERK↓, Akt↓, NF-kB↓, Inflam↓, AntiTum↓,
7690- IP6,  Ins,    Inositol Hexaphosphate (IP6) and Colon Cancer: From Concepts and First Experiments to Clinical Application
- Review, Colon, NA
AntiCan↑, Imm↑, antiOx↑, TumCP↓, Diff↑, TumCG↓, eff↑, P21↓, p27/CDKN1B↓, pRB↓, TumCCA↑, PI3K↓, Akt↓, PKCδ↓, RAS↓, ERK↓, NF-kB↓, Inflam↓, MMP9↓, IronCh↑, NK cell↑, selectivity↑, ChemoSen↑, chemoP↑, toxicity↓, Remission↑,
7696- IP6,  Ins,    The Combination of Inositol Hexaphosphate and Inositol Inhibits Metastasis of Colorectal Cancer Cells by Upregulating Claudin 7
- vitro+vivo, Colon, SW48 - in-vitro, Colon, SW-620
AntiCan↑, CLDN7↑, EMT↓, E-cadherin↑, N-cadherin↓, eff↑, TumCG↓,
7701- IP6,    Inositol hexaphosphate sensitizes hepatocellular carcinoma to oxaliplatin relating inhibition of CCN2-LRP6-β-catenin-ABCG1 signaling pathway
- vitro+vivo, HCC, Hep3B - NA, NA, MHCC-97H
AntiCan↑, ChemoSen↑, LRP6↓, Wnt↓, β-catenin/ZEB1↓, CCN2/CTGF↓, ABCG1↓, TumCP↓, TumCMig↓,
7763- ISL,    Harnessing Liquiritigenin: A Flavonoid-Based Approach for the Prevention and Treatment of Cancer
AntiCan↑, *antiOx↓, *Inflam↓, TumCP↓, Apoptosis↑, NF-kB↓, PI3K↓, Akt↓, mTOR↓, *AntiArt↑, Casp8↑, Cyt‑c↑, Casp↑, cl‑PARP↑, GutMicro↑, BioAv↑, BioAv↓, Half-Life↓,
7745- ISL,    Isoliquiritigenin inhibits colorectal cancer progression by targeting the FGFR4/FASN mediated lipid metabolism pathway
- in-vitro, CRC, NA
AntiCan↑, TumCP↓, TumCMig↓, FASN↓, FGFR4/CD334↓, PI3K↓, Akt↓,
7746- ISL,    Isoliquiritigenin Inhibits the Growth of Colorectal Cancer Cells through the ESR2/PI3K/AKT Signalling Pathway
- vitro+vivo, CRC, SW480 - vitro+vivo, CRC, HCT116
AntiCan↑, tumCV↓, Apoptosis↑, TumCCA↑, TumCG↓, PI3K↓, Akt↓, p‑Akt↓, p‑GSK‐3β↓, CDK1↓, NF-kB↓, Bcl-2↓, ERβ/ESR2↑, BAX↑, Bax:Bcl2↑, ROS↑,
7750- ISL,    Isoliquiritigenin in Breast Cancer: A Systematic Review of Its Preventive and Anti-metastatic Mechanisms
- Review, BC, NA
AntiCan↑, Apoptosis↑, TumAuto↑, mTOR↓, AApath↓, EMT↓, BRCA1↝, PI3K↓, Akt↓, angioG↓, VEGF↓, Hif1a↓, COX2/PTGS2↓, NF-kB↓,
7756- ISL,    Dietary compound isoliquiritigenin inhibits breast cancer neoangiogenesis via VEGF/VEGFR-2 signaling pathway
- vitro+vivo, BC, MCF7 - vitro+vivo, BC, MDA-MB-231
AntiCan↑, VEGF↓, TumCI↓, TumCMig↓, Hif1a↓, TumCG↓, angioG↓, VEGFR2/KDR/Flk1↓, Apoptosis↑, toxicity↓, TumCCA↑, Inflam↓, ROS↑,
7765- ISL,    Isoliquiritigenin as a modulator of the Nrf2 signaling pathway: potential therapeutic implications
- Review, Var, NA
*antiOx↑, *AntiCan↑, *AntiTum↑, *AntiDiabetic↑, *cardioP↑, *RenoP↑, *NRF2↑, *NQO1↝, *HO-1↑, *SOD↑, *toxicity↓, *BioAv↓, *Half-Life↓, *BBB↑, *neuroP↑, *Stroke↓, *GSK‐3β↓, *p‑GSK‐3β↑, *hepatoP↑, *Inflam↓, *ROS↓, *MPO↓, *MDA↓,
7868- isoO,    Isoorientin Suppresses Invasion of Breast and Colon Cancer Cells by Inhibition of CXC Chemokine Receptor 4 Expression
*antiOx↑, *AntiCan↑, *Inflam↓, CXCR4↓, NF-kB↓,
7814- ISQ,    Isoquercitrin Attenuates Steatohepatitis by Inhibition of the Activated NLRP3 Inflammasome through HSP90
- in-vivo, Nor, NA
*ROS↓, *AntiCan↑, *cardioP↑, *AntiDiabetic↑, *NLRP3↓, *HSP90↓, *AST↓, *ALAT↓,
7800- ISQ,    Isoquercitrin Attenuates Oxidative Liver Damage Through AMPK-YAP Signaling: An Integrative In Silico, In Vitro, and In Vivo Study
- vitro+vivo, Nor, HepG2
*antiOx↑, *Inflam↓, *AntiCan↑, *ROS↓, *MMP↑, *STK11/LKB1↑, *AMPK↑, *p‑AMPK↑, *ACC↑, *ALAT↓, *AST↓, *hepatoP↑,
8001- itraC,    Repurposing itraconazole as an anticancer agent
- Review, Var, NA
*AntiFungal↑, AntiCan↑, P-gp/ABCB1↓, HH↓, mTOR↓, Wnt↓, β-catenin/ZEB1↓, angioG↓, LymphAG↓, ChemoSen↑, OS↑, Gli1↓, Ki-67↓, CSCs↓,
8035- IVM,    Ivermectin and non-parasitic disorders: An update
- Review, Var, NA - Review, AD, NA - Review, Stroke, NA
*AntiP↑, angioG↓, *AntiCan↓, mtDam↑, Apoptosis↑, necrosis↑, TumAuto↑, ROS↑, *neuroP↑, *Stroke↝, *cardioP↑,
8049- IVM,    Ivermectin Induces Cytostatic Autophagy by Blocking the PAK1/Akt Axis in Breast Cancer
- vitro+vivo, BC, NA
*AntiP↑, AntiCan↑, AntiTum↑, PAK1↓, p‑Akt↓, Akt↓, mTOR↓, TumCG↓,
7917- IVT,    A review on the pharmacological effects of vitexin and isovitexin
- Review, Nor, NA - Review, AD, NA
*antiOx↑, *AntiCan↑, *Inflam↓, *neuroP↑, *AChE↓, *BChE↓, *BACE/β-secretase↓, *Stroke↓, *AntiAg↓, *AntiDiabetic↑, *AGEs↓, *IL1β↓, *IL6↓, *IL8↓, *TNF-α↓, *Obesity↓, *BioAv↝, *BioAv↓,
7900- IVT,    Isovitexin: A Promising Active Compound Found in Nature's Bounty
- in-vivo, Nor, NA
*BioAv↓, *Imm↝, *antiOx↑, *AntiCan↑, *neuroP↑, *hepatoP↑, *Inflam↓, *NF-kB↓, *MAPK↓, *MPO↓, *ROS↓, TumAuto↑, Apoptosis↑,
8007- JG,    Juglone reduces growth and migration of U251 glioblastoma cells and disrupts angiogenesis
- in-vitro, GBM, U251
Pin1↓, AntiCan↑, TumCP↓, Apoptosis↑, Casp3↑, TumCMig↓, angioG↓, VEGF↓, CD31/PECAM-1↓, TGF-β1↓,
8004- JG,    TP53 Is a Potential Target of Juglone Against Colorectal Cancer: Based on a Combination of Molecular Docking, Molecular Dynamics Simulation, and In Vitro Experiments
*Inflam↓, *AntiViral↑, *AntiCan↑, ROS↑, P53↑, TumCP↓,
8088- KAE,    Kaempferol: Antimicrobial Properties, Sources, Clinical, and Traditional Applications
- Review, Nor, NA
*AntiCan↓, *Inflam↓, *Bacteria↓, *AntiFungal↑, *BioAv↝,
8090- KAE,    A systematic review of anti-cancer roles and mechanisms of kaempferol as a natural compound
- Review, Nor, NA
*cardioP↑, *AntiCan↑, *Inflam↓, *neuroP↑, *BioAv↓, selectivity?, p‑Akt↓, p‑cycD1/CCND1↓, p‑CDK4↓, p‑BID↓, p‑Mcl-1↓, p‑BRCA1↑, ATM↑, P53↑, P21↑, p38↑, BAX↑, BID↑, MMP↓, Casp3↑, Casp7↑, Casp9↑, AIF↑, ER Stress↑, TumMeta↓, ERK↓, AP-1↓, JNK↓, p38↓, GLUT1↓, GlucoseCon↓, MMP9↓, CYP1A1↓, ChemoSen↑, OCT4↓, Nanog↓, P-gp/ABCB1↓, ALDH1A1↓, TumCCA↑, DNAdam↑, γH2AX↑, COX2/PTGS2↓, i-ROS↓, Ca+2↓, eff↑, DR5↑, ChemoSen↑, Akt↓, PI3K↓, ROS↑, EMT↓, survivin↓,
8064- KAE,    Kaempferol Inhibits Pancreatic Cancer Cell Growth and Migration through the Blockade of EGFR-Related Pathway In Vitro
- in-vitro, PC, MIA PaCa-2 - in-vitro, PC, PANC1 - in-vitro, PC, SNU-213
AntiCan↑, tumCV↓, Apoptosis↑, TumCMig↓, *toxicity↓, Dose?,
8067- KAE,  Cisplatin,    Kaempferol Induces Cell Death and Sensitizes Human Head and Neck Squamous Cell Carcinoma Cell Lines to Cisplatin
- in-vitro, HNSCC, NA
AntiCan↑, OCR↓, i-ATP↓, TumCMig↓, TumCP↓, Apoptosis↑, ChemoSen↑,
8072- KAE,    Natural defense against colorectal cancer: the effects of kaempferol on epigenetics, apoptosis, inflammation, oxidative stress, and cell proliferation
- Review, CRC, NA
AntiCan↑, TumCP↓, TumCI↓, Inflam↓, angioG↓, ROS↑, Apoptosis↑, ChemoSen↑, Risk↓, *antiOx↑, *Inflam↓, *AntiBio↑, *cardioP↑, *neuroP↑, selectivity↑, PUMA↑, Cyt‑c↑, cl‑Casp3↑, cl‑PARP↑, Apoptosis↑, NF-kB↓, COX2/PTGS2↓, CC(CDKs/cyclins)↓, TumCCA↑, BioAv↓, eff↑, DR4↑, DR5↑, Casp3↑, Casp9↑, Casp7↑, TumCP↓, TumCI↓, TumAuto↑, mtDam↑, P53↑, MAPK↑, *lipid-P↓, *TAC↑, *Catalase↑, *SOD↑, *GPx↑, *NRF2↑,
8079- KAE,    Endoplasmic Reticulum Stress-Mediated Apoptosis Induced by Kaempferol in Colorectal Cancer Cells
- in-vitro, CRC, DLD1 - in-vitro, Lung, A549 - in-vitro, Liver, HUH7 - in-vitro, Cerv, HeLa
*antiOx↑, *AntiBio↑, *AntiDiabetic↑, *AntiCan↑, Dose↝, TumCP↓, ER Stress↑, Apoptosis↑, Bcl-2↓, BAX↑, Casp3↑, Casp9↑, Casp12↝, NF-kB↓, P53↑,
8081- KAE,    The Anticancer Effects and Therapeutic Potential of Kaempferol in Triple-Negative Breast Cancer
- Review, BC, NA
*antiOx↓, *Inflam↓, *neuroP↓, *AntiCan↑, DNAdam↓, Casp3↑, Casp9↑, p‑AMT/GCST/T-protein↑, ROS↑, NRF2↑, Apoptosis↑, cl‑PARP↓, BAX↑, Bcl-2↓, TumCCA↓, angioG↓, MMP3↓, MMP9↓, ChemoSen↑, BioAv↓, Glycolysis↓, cl‑PARP↑, Ca+2↑, MMP↓, ER Stress↑, GRP78/BiP↑, CHOP/DDIT3↑, ATF6↑, angioG↓, VEGF↓, Hif1a↓, chemoP↑, *ROS↓, NRF2↑, BioAv↑,
8146- Lae,    Laetrile treatment for cancer
- Review, Var, NA
AntiCan↝, toxicity↑,
8156- lamb,    A review on chemistry, source and therapeutic potential of lambertianic acid
- Review, Var, NA
*Obesity↓, *AntiCan↑, *AMPK↑, *β-HEX↓, NA↑, TumCCA↑, AMPK↑, ACC↑, p‑Akt↓, FOXM1↓, CycB/CCNB1↓, XIAP↓, Bcl-2↓, p‑STAT3↓, p‑NF-kB↓, Bcl-xL↓, survivin↓, VEGF↓, COX2/PTGS2↓, cMyc↓, IL6↓, TNF-α↓, ROS↑, STK11/LKB1↑, cl‑Casp3↑, cl‑PARP↑, eff↑, AR↓, TumCP↓, p‑P53↓, P21↓, p27/CDKN1B↓, cycD1/CCND1↓, CDK4↓, PSA↓, STAT3↓, ac‑p65↓, *antiAll↑,
8208- LCA,    Licochalcone A inhibits PI3K/Akt/mTOR signaling pathway activation and promotes autophagy in breast cancer cells
- in-vitro, BC, MCF7
*Inflam↓, *AntiCan↑, *AntiP↑, LC3II↑, PI3K↓, Akt↓, mTOR↓, Casp3↑, Bcl-2↓, TumAuto↑, Apoptosis↑, tumCV?,
8211- LCA,    Licochalcone A induces endoplasmic reticulum stress-mediated apoptosis of endometrial cancer cells via upregulation of GRP78 expression
- in-vitro, EC, NA
AntiCan↑, tumCV↓, Apoptosis↑, ER Stress↑, GRP78/BiP↑, CHOP/DDIT3↑,
8218- LCA,    Advances in Pharmacological Activities and Drug Delivery Systems of Licochalcone A
- Review, Nor, NA
*Inflam↓, *antiOx↑, *AntiTum↑, *hepatoP↑, *Bacteria↓, AntiCan↑, BioAv↓, BioAv↑,

Showing Research Papers: 251 to 300 of 440
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 440

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

6IL↑, 1,   AApath↓, 1,   ABCG1↓, 1,   p‑AMT/GCST/T-protein↑, 1,   CLDN7↑, 1,   CYP2D6↓, 1,   DHODH↓, 1,   FGFR4/CD334↓, 1,   NA↑, 1,   PSEN2/PS-2↓, 1,   TF-Ag↓, 1,   UGT1A↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 2,   CYP1A1↓, 1,   CYP2E1↓, 1,   NRF2↑, 2,   ROS↑, 10,   i-ROS↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 1,   i-ATP↓, 1,   MMP↓, 3,   MPT↑, 1,   mtDam↑, 3,   OCR↓, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACC↑, 1,   AKT1↓, 1,   AMPK↑, 2,   cMyc↓, 1,   FASN↓, 1,   GlucoseCon↓, 1,   Glycolysis↓, 2,   PPARγ↑, 2,   S6K↓, 1,   STK11/LKB1↑, 2,  

Cell Death(tgid=5) ⓘ

Akt↓, 14,   p‑Akt↓, 7,   Apoptosis↑, 21,   BAX↑, 4,   Bax:Bcl2↑, 1,   Bcl-2↓, 5,   Bcl-xL↓, 1,   BID↑, 1,   p‑BID↓, 1,   Casp↑, 1,   Casp12↝, 1,   Casp3↑, 7,   cl‑Casp3↑, 2,   Casp7↑, 2,   Casp8↑, 1,   Casp9↑, 5,   Cyt‑c↑, 2,   DR4↑, 1,   DR5↑, 2,   JNK↓, 1,   MAPK↑, 2,   p‑Mcl-1↓, 1,   necrosis↑, 2,   p27/CDKN1B↓, 3,   p27/CDKN1B↑, 2,   p38↓, 1,   p38↑, 1,   PUMA↑, 1,   survivin↓, 2,   TumCD↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

pRB↓, 2,   p‑pRB↓, 1,   tumCV?, 1,   tumCV↓, 5,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 1,   CHOP/DDIT3↑, 2,   ER Stress↑, 4,   GRP78/BiP↑, 2,  

Autophagy & Lysosomes(tgid=9) ⓘ

LC3II↑, 1,   TumAuto↑, 6,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 1,   BRCA1↝, 1,   p‑BRCA1↑, 1,   DNAdam↓, 1,   DNAdam↑, 1,   P53↑, 4,   p‑P53↓, 1,   cl‑PARP↓, 1,   cl‑PARP↑, 4,   PCNA↓, 1,   γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK4↓, 1,   p‑CDK4↓, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 1,   p‑cycD1/CCND1↓, 1,   P21↓, 2,   P21↑, 2,   TumCCA↓, 1,   TumCCA↑, 8,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH1A1↓, 1,   CSCs↓, 1,   Diff↑, 3,   EMT↓, 4,   ERK↓, 5,   FOXM1↓, 1,   Gli1↓, 1,   p‑GSK‐3β↓, 1,   HH↓, 1,   IGF-1↓, 2,   LRP6↓, 1,   mTOR↓, 7,   Nanog↓, 1,   OCT4↓, 1,   PI3K↓, 13,   RAS↓, 2,   STAT3↓, 1,   p‑STAT3↓, 2,   TumCG↓, 6,   Wnt↓, 3,  

Migration(tgid=13) ⓘ

AP-1↓, 1,   Ca+2↓, 1,   Ca+2↑, 2,   CC(CDKs/cyclins)↓, 1,   CCN2/CTGF↓, 1,   CD31/PECAM-1↓, 1,   E-cadherin↑, 2,   Ki-67↓, 2,   MMP1↓, 1,   MMP13↓, 1,   MMP2↓, 1,   MMP3↓, 2,   MMP9↓, 5,   N-cadherin↓, 1,   PAK1↓, 1,   PKCδ↓, 1,   PKCδ↑, 1,   TGF-β1↓, 1,   TIMP1↓, 1,   TIMP2↓, 1,   TumCA↓, 1,   TumCI↓, 4,   TumCMig↓, 7,   TumCP↓, 15,   TumMeta↓, 1,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 9,   HIF-1↓, 1,   Hif1a↓, 3,   LymphAG↓, 1,   VEGF↓, 5,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↓, 1,   P-gp/ABCB1↓, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 4,   CXCR4↓, 1,   IL6↓, 2,   Imm↑, 1,   Inflam↓, 5,   NF-kB↓, 9,   p‑NF-kB↓, 1,   NK cell↑, 1,   ac‑p65↓, 1,   PSA↓, 1,   TNF-α↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 1,   ERβ/ESR2↑, 1,   EstroRS/ERS↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 4,   BioAv↑, 3,   ChemoSen↑, 8,   CYP2C9↓, 1,   Dose?, 1,   Dose↝, 2,   eff↑, 5,   Half-Life↓, 1,   selectivity?, 1,   selectivity↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 1,   BRCA1↝, 1,   p‑BRCA1↑, 1,   EstroRS/ERS↓, 1,   FOXM1↓, 1,   GutMicro↑, 1,   IL6↓, 2,   Ki-67↓, 2,   PSA↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 32,   AntiCan⇅, 2,   AntiCan↝, 1,   antiNeop↑, 1,   AntiTum↓, 1,   AntiTum↑, 1,   chemoP↑, 2,   chemoPv↑, 3,   OS↑, 1,   Pin1↓, 1,   Remission↑, 1,   Risk↓, 2,   toxicity↓, 3,   toxicity↑, 1,   TumVol↓, 1,  
Total Targets: 199

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

antiAll↑, 1,   AntiArt↑, 1,   AntiBio↑, 3,   AntiP↑, 3,   FFA/NEFA↓, 1,   IRes↓, 1,   Stroke↓, 2,   Stroke↝, 1,   β-HEX↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 3,   antiOx↑, 10,   Catalase↑, 1,   GPx↑, 1,   HO-1↑, 1,   lipid-P↓, 1,   MDA↓, 1,   MPO↓, 2,   NQO1↝, 1,   NRF2↑, 2,   ROS↓, 6,   SOD↑, 2,   TAC↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACC↑, 1,   ALAT↓, 2,   AMPK↑, 2,   p‑AMPK↑, 1,   FASN↓, 1,   glucose↝, 1,   LDL↓, 1,   STK11/LKB1↑, 1,  

Cell Death(tgid=5) ⓘ

MAPK↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

HSP90↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNArepair↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

GSK‐3β↓, 1,   p‑GSK‐3β↑, 1,   PI3K↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 1,   AntiAg↑, 1,   AP-1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IL1β↓, 1,   IL6↓, 1,   IL8↓, 1,   Imm↝, 1,   Inflam↓, 16,   NF-kB↓, 1,   PGE2↓, 1,   TNF-α↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   BChE↓, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 1,   BACE/β-secretase↓, 1,   NLRP3↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 4,   BioAv↑, 1,   BioAv↝, 2,   Half-Life↓, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   AST↓, 2,   IL6↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↓, 2,   AntiCan↑, 13,   AntiDiabetic↑, 5,   AntiTum↑, 2,   cardioP↑, 5,   hepatoP↑, 4,   neuroP↓, 1,   neuroP↑, 8,   Obesity↓, 2,   RenoP↑, 1,   toxicity↓, 3,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 3,   AntiViral↑, 1,   Bacteria↓, 2,  
Total Targets: 76

Scientific Paper Hit Count for: AntiCan, Anticancer Effect
18 Silver-NanoParticles
12 Lycopene
10 Thymoquinone
10 Selenium NanoParticles
9 Emodin
9 Inositol
9 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
8 Capsaicin
8 Magnolol
7 Allicin (mainly Garlic)
7 Curcumin
7 Gambogic Acid
7 Kaempferol
7 Phenethyl isothiocyanate
7 Quercetin
7 Sulforaphane (mainly Broccoli)
6 Vitamin C (Ascorbic Acid)
6 Astaxanthin
6 Baicalein
6 Eugenol
6 Honokiol
6 Isoliquiritigenin
6 Selenite (Sodium)
5 Coenzyme Q10
5 Artemisinin
5 EGCG (Epigallocatechin Gallate)
5 Lactoferrin/Talactoferrin
4 chitosan
4 Apigenin (mainly Parsley)
4 Boron
4 Carvacrol
4 Chlorogenic acid
4 Crocetin
4 Dandelion Root
4 Ferulic acid
4 Isovitexin
4 Naringin
4 Selenium
3 Cisplatin
3 Melatonin
3 Aloe anthraquinones
3 beta-glucans
3 Biochanin A
3 α-Bisabolol / Chamomile oil
3 Hydroxycinnamic-acid
3 Resveratrol
3 Spermidine
3 Carvone
3 Cynara scolymus/Globe Artichoke/Artichoke Extract
3 Cucurbitacin
3 Date Fruit Extract
3 Lemongrass Extract/Citral
3 Ellagic acid
3 flavonoids
3 Formononetin
3 Fucoidan
3 Gallic acid
3 Garcinol
3 Geraniol
3 Ginkgetin
3 HydroxyTyrosol
3 Hyperoside
3 Isobavachalcone
3 Licochalcone A
3 Propolis -bee glue
3 Pterostilbene
3 salinomycin
3 Silymarin (Milk Thistle) silibinin
3 Vitamin D3
3 Vitamin K2
2 3-bromopyruvate
2 5-fluorouracil
2 Auranofin
2 doxorubicin
2 Alpha-Lipoic-Acid
2 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
2 Anethole/trans-Anethole
2 Baicalin
2 Beta-Caryophyllene
2 Boswellia (frankincense)
2 Butyrate
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Thymol-Thymus vulgaris
2 Chlorophyllin
2 Chrysin
2 Cinnamon
2 Camptothecin
2 Dichloroacetate
2 diet Fermented Foods
2 Ginkgo biloba-EGb 761
2 Germanium Organic/Ge-132 / propagermanium (organogermanium)
2 Hydrogen Gas
2 Hibiscus sabdariffa
2 iodine
2 isoquercitrin
2 Ivermectin
2 Juglone
2 Vitexin
2 Magnetic Fields
2 Bicarbonate(Sodium)
2 Piperine
2 Rosmarinic acid
2 Rauwolfia serpentina/Indian Snakeroot
2 Shikonin
2 Ursolic acid
2 Urolithin
2 VitK3,menadione
1 1,8-Cineole
1 Astragalus
1 Citric Acid
1 Ashwagandha(Withaferin A)
1 Ascorbyl Palmitate
1 Berberine
1 Betulinic acid
1 Bromelain
1 borneol
1 Bruteridin(bergamot juice)
1 Vitamin B3,Niacin
1 Caffeic acid
1 Caffeine
1 urea
1 Celastrol
1 Centella asiatica / Gotu kola → asiaticoside
1 chaetocin
1 Carica papaya leaf extract
1 irinotecan
1 Calorie Restriction Mimetics
1 Aspirin
1 Polyphenols
1 Diclofenac
1 diet FMD Fasting Mimicking Diet
1 diet Methionine-Restricted Diet
1 diet Plant based
1 Electrical Pulses
1 Eurycomanone
1 Evodiamine
1 ferumoxytol
1 Fisetin
1 Paclitaxel/Taxol
1 Gamma-aminobutyric acid
1 Ginkgo biloba
1 Geldanamycin
1 Genistein (soy isoflavone)
1 Ginger/6-Shogaol/Gingerol
1 γ-linolenic acid (Borage Oil)
1 alpha Linolenic acid
1 Graviola
1 Grapeseed extract
1 Germacranolide sesquiterpene lactone
1 Chemotherapy
1 High-Ozonide Oil
1 Hops (Humulus lupulus)
1 Indole-3-carbinol
1 isoorientin
1 itraconazole
1 Laetrile B17 Amygdalin
1 lambertianic acid
1 Licorice
1 Lecithin
1 Luteolin
1 Methylene blue
1 Photodynamic Therapy
1 Mung Bean Sprouts
1 mebendazole
1 Metformin
1 Magnetic Field Rotating
1 Methylglyoxal
1 Nimbolide
1 Oleocanthal
1 Oregano
1 Piperlongumine
1 Psoralidin
1 Parthenolide
1 Gold NanoParticles
1 Salvia officinalis
1 Radiotherapy/Radiation
1 α-Santalol/Sandalwood oil
1 Calcium
1 Aflavin-3,3′-digallate
1 Magnesium
1 Zerumbone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:813  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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