tumCV Cancer Research Results

tumCV, Cell Viability: Click to Expand ⟱
Source:
Type:
Cell Viability
Scientific Papers found: Click to Expand⟱
5222- TQ,    Thymoquinone chemosensitizes colon cancer cells through inhibition of NF-κB
- in-vitro, CRC, COLO205 - in-vitro, CRC, HCT116
tumCV↓, ChemoSen↑, p‑p65↓, NF-kB↓, VEGF↓, cMyc↓, Bcl-2↓, ROS↑,
1308- TQ,    Thymoquinone induces apoptosis via targeting the Bax/BAD and Bcl-2 pathway in breast cancer cells
- in-vitro, BC, MCF-7
tumCV↓, TumCP↓, BAX↑, P53⇅, Apoptosis↑,
2135- TQ,    Thymoquinone induces heme oxygenase-1 expression in HaCaT cells via Nrf2/ARE activation: Akt and AMPKα as upstream targets
- in-vitro, Nor, HaCaT
*HO-1↑, *NRF2↑, *e-ERK↑, *e-Akt↑, *AMPKα↑, *ROS⇅, *eff↓, *tumCV∅,
2099- TQ,  Cisplatin,    Thymoquinone and cisplatin as a therapeutic combination in lung cancer: In vitro and in vivo
- in-vitro, Lung, H460 - in-vitro, Lung, H146 - in-vivo, NA, NA
ChemoSen↑, TumCP↓, tumCV↓, Apoptosis↑, NF-kB↓,
2105- TQ,    Thymoquinone Promotes Pancreatic Cancer Cell Death and Reduction of Tumor Size through Combined Inhibition of Histone Deacetylation and Induction of Histone Acetylation
- in-vitro, PC, AsPC-1 - in-vitro, PC, MIA PaCa-2 - in-vitro, PC, Hs766t - in-vivo, NA, NA
tumCV↓, TumCP↓, TumCCA↑, Apoptosis↑, P53↑, Bcl-2↓, P21↑, ac‑H4↑, HDAC↓, HDAC1↓, HDAC2↓, HDAC3↓, TumVol↓,
2107- TQ,    Cytotoxicity of Nigella sativa seed oil and extract against human lung cancer cell line
- in-vitro, Lung, A549
tumCV↑,
2110- TQ,    Nigella sativa seed oil suppresses cell proliferation and induces ROS dependent mitochondrial apoptosis through p53 pathway in hepatocellular carcinoma cells
- in-vitro, HCC, HepG2 - in-vitro, BC, MCF-7 - in-vitro, Lung, A549 - in-vitro, Nor, HEK293
P53↑, lipid-P↑, GSH↓, ROS↑, MMP↓, BAX↑, Casp3↑, Casp9↑, Bcl-2↓, tumCV↓, selectivity↑,
1929- TQ,    Thymoquinone Suppresses the Proliferation, Migration and Invasiveness through Regulating ROS, Autophagic Flux and miR-877-5p in Human Bladder Carcinoma Cells
- in-vitro, Bladder, 5637 - in-vitro, Bladder, T24/HTB-9
tumCV↓, TumCP↓, TumCI↓, Casp↑, ROS↑, PD-L1↓, EMT↓, MMP↓, eff↓,
1931- TQ,  doxoR,    Thymoquinone enhances the anticancer activity of doxorubicin against adult T-cell leukemia in vitro and in vivo through ROS-dependent mechanisms
- in-vivo, AML, NA
eff↑, tumCV↓, TumCCA↑, ROS↑, MMP↓, eff↑, TumVol↓, eff↑, Ki-67↓,
3413- TQ,    Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Src‑mediated phosphorylation of EGF receptor tyrosine kinase
- in-vitro, CRC, HCT116
tumCV↓, Apoptosis↓, BAX↑, Bcl-2↓, Casp9↑, Casp7↑, Casp3↑, cl‑PARP↑, STAT3↓, survivin↓, cMyc↓, cycD1/CCND1↓, p27↑, P21↑, EGFR↓, ROS↑,
3414- TQ,    Thymoquinone induces apoptosis through inhibition of JAK2/STAT3 signaling via production of ROS in human renal cancer Caki cells
- in-vitro, RCC, Caki-1
tumCV↓, Apoptosis↑, P53↑, BAX↑, Cyt‑c↑, cl‑Casp9↑, cl‑Casp3↑, cl‑PARP↑, Bcl-2↓, Bcl-xL↓, p‑STAT3↓, p‑JAK2↓, STAT3↓, survivin↓, cycD1/CCND1↓, ROS↑, eff↓,
3403- TQ,    A multiple endpoint approach reveals potential in vitro anticancer properties of thymoquinone in human renal carcinoma cells
- in-vitro, RCC, 786-O
tumCV↓, ROS↑, TumCCA↑, eff↓, TumCI↓,
3402- TQ,    Enhanced Apoptosis in Pancreatic Cancer Cells through Thymoquinone-rich Nigella sativa L. Methanol Extract: Targeting NRF2/HO-1 and TNF-α Pathways
- in-vitro, PC, PANC1 - in-vitro, PC, MIA PaCa-2
tumCV↓, NRF2↑, HO-1↑, TNF-α↓,
3415- TQ,    The anti-neoplastic impact of thymoquinone from Nigella sativa on small cell lung cancer: In vitro and in vivo investigations
- in-vitro, Lung, H446
tumCV↓, TumCCA↑, ROS↓, CycB/CCNB1↑, CycD3↑, cycA1/CCNA1↓, cycE/CCNE↓, cDC2↓, antiOx↑, PARP↓, NRF2↓, ARE/EpRE↑, eff↑,
5020- UA,    Anticancer activity of ursolic acid on human ovarian cancer cells via ROS and MMP mediated apoptosis, cell cycle arrest and downregulation of PI3K/AKT pathway
- in-vitro, Ovarian, NA
tumCV↓, selectivity↑, BAX↑, Bcl-2↓, Apoptosis↑, ROS↑, TumCCA↑, Akt↓, PI3K↓,
5021- UA,    Anticancer effect of ursolic acid via mitochondria-dependent pathways
- Review, Var, NA
Inflam↓, TNF-α↓, IL6↓, IL17↓, NF-kB↓, COX2↓, *AntiDiabetic↑, *hepatoP↑, ALAT↓, AST↓, TumCP↓, Apoptosis↑, TumCCA↑, TumAuto↑, tumCV↓, TumCMig↓, Glycolysis↓, ATP↓, lactateProd↓, HK2↓, PKA↓, COX2↓, mtDam↑, Casp3↑, Casp8↑, Casp9↑, Akt↓, ROS↑, MMP↓, P53↑,
4857- Uro,    Evaluation and comparison of the anti-proliferative and anti-metastatic effects of urolithin A and urolithin B against esophageal cancer cells: an in vitro and in silico study
- in-vitro, ESCC, KYSE-30
tumCV↓, selectivity↑, TumCCA↑, ROS↑, Bcl-2↓, BAX↑, P21↑, MMP2↓, MMP9↓,
4839- Uro,    Urolithin A induces prostate cancer cell death in p53-dependent and in p53-independent manner
- in-vitro, Pca, 22Rv1 - in-vitro, Pca, LNCaP
tumCV↓, Apoptosis↓, P53↑, P21↑, PUMA↑, NOXA↑, MDM2↓, XIAP↓,
4840- Uro,    Urolithin A: A promising selective estrogen receptor modulator and 27-hydroxycholesterol attenuator in breast cancer
- vitro+vivo, BC, NA
MMP↓, TumCP↓, Apoptosis↑, tumCV↓, ER-α36↝, *toxicity↓,
3141- VitC,    High-dose Vitamin C inhibits PD-L1 expression by activating AMPK in colorectal cancer
- in-vitro, CRC, HCT116
Glycolysis↓, eff↑, PD-L1↓, AMPK↑, HK2↓, NF-kB↓, Warburg↓, tumCV↓, GLUT1↓, PKM2↓, LDHA↓, CD4+↑, CD8+↑,
3119- VitC,    Ascorbic acid–induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma
- in-vitro, RCC, NA
TET2↑, TumCG↓, tumCV↓,
1836- VitC,  VitK3,  Chemo,    Vitamins C and K3: A Powerful Redox System for Sensitizing Leukemia Lymphocytes to Everolimus and Barasertib
- in-vitro, AML, NA
tumCV↓, selectivity↑, Apoptosis↑, eff↑, ChemoSen↑,
1216- VitC,    Ascorbic acid induces ferroptosis via STAT3/GPX4 signaling in oropharyngeal cancer
- in-vitro, Laryn, FaDu - in-vitro, SCC, SCC-154
Iron↝, ROS↑, tumCV↓, Ki-67↓, TumCCA↑, Ferroptosis↑, GSH↓, ROS↑, MDA↑, STAT3↓, GPx4↓, p‑STAT3↓,
2366- VitD3,    Vitamin D3 decreases glycolysis and invasiveness, and increases cellular stiffness in breast cancer cells
- in-vitro, BC, MCF-7
Glycolysis↓, tumCV↓, Apoptosis↑, mTOR↓, AMPK↑, EMT↓, E-cadherin↑, F-actin↑, Vim↓,
2279- VitK2,    Vitamin K2 Induces Mitochondria-Related Apoptosis in Human Bladder Cancer Cells via ROS and JNK/p38 MAPK Signal Pathways
- in-vitro, Bladder, T24/HTB-9 - in-vitro, Bladder, J82 - in-vitro, Nor, HEK293 - in-vitro, Nor, L02 - in-vivo, NA, NA
MMP↓, Cyt‑c↑, Casp3↑, p‑JNK↑, p‑p38↑, ROS↑, eff↓, tumCV↓, selectivity↑, *toxicity↓, TumVol↓,
1838- VitK3,  PDT,    Photodynamic Effects of Vitamin K3 on Cervical Carcinoma Cells Activating Mitochondrial Apoptosis Pathways
- in-vitro, Cerv, NA
eff↑, ROS↑, tumCV↓, TumCG↓, Apoptosis↑, cl‑Casp3↑, cl‑Casp9↑, Bcl-xL↑, Cyt‑c↑, Bcl-2↓,
1755- WBV,    Reduction of breast cancer extravasation via vibration activated osteocyte regulation
Dose∅, TumMeta↑, eff∅, Piezo1↑, COX2↑, RANKL↓, TumCG∅, tumCV∅, TumCI↓,
4888- ZER,  5-FU,    Modulation of the tumor microenvironment by zerumbone and 5-fluorouracil in colorectal cancer by target in cancer-associated fibroblasts
- in-vitro, CRC, CT26
TumVol↓, *tumCV↓, survivin↓, β-catenin/ZEB1↓, Vim↓,
4887- ZER,  Rad,  Cisplatin,    Zerumbone acts as a radiosensitizer in head and neck squamous cell carcinoma
- in-vitro, HNSCC, CAL27
Apoptosis↑, ChemoSen↑, RadioS↑, tumCV↓,

Showing Research Papers: 301 to 329 of 329
Prev Page 7 of 7

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 329

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,   ARE/EpRE↑, 1,   Ferroptosis↑, 1,   GPx4↓, 1,   GSH↓, 2,   HO-1↑, 1,   Iron↝, 1,   lipid-P↑, 1,   MDA↑, 1,   NRF2↓, 1,   NRF2↑, 1,   ROS↓, 1,   ROS↑, 14,  

Mitochondria & Bioenergetics ⓘ

ATP↓, 1,   MMP↓, 6,   mtDam↑, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 1,   AMPK↑, 2,   cMyc↓, 2,   Glycolysis↓, 3,   HK2↓, 2,   lactateProd↓, 1,   LDHA↓, 1,   PKM2↓, 1,   Warburg↓, 1,  

Cell Death ⓘ

Akt↓, 2,   Apoptosis↓, 2,   Apoptosis↑, 11,   BAX↑, 6,   Bcl-2↓, 8,   Bcl-xL↓, 1,   Bcl-xL↑, 1,   Casp↑, 1,   Casp3↑, 4,   cl‑Casp3↑, 2,   Casp7↑, 1,   Casp8↑, 1,   Casp9↑, 3,   cl‑Casp9↑, 2,   Cyt‑c↑, 3,   Ferroptosis↑, 1,   p‑JNK↑, 1,   MDM2↓, 1,   NOXA↑, 1,   p27↑, 1,   p‑p38↑, 1,   PUMA↑, 1,   survivin↓, 3,  

Transcription & Epigenetics ⓘ

ac‑H4↑, 1,   tumCV↓, 25,   tumCV↑, 1,   tumCV∅, 1,  

Autophagy & Lysosomes ⓘ

TumAuto↑, 1,  

DNA Damage & Repair ⓘ

P53↑, 5,   P53⇅, 1,   PARP↓, 1,   cl‑PARP↑, 2,  

Cell Cycle & Senescence ⓘ

cycA1/CCNA1↓, 1,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 2,   CycD3↑, 1,   cycE/CCNE↓, 1,   P21↑, 4,   TumCCA↑, 8,  

Proliferation, Differentiation & Cell State ⓘ

cDC2↓, 1,   EMT↓, 2,   HDAC↓, 1,   HDAC1↓, 1,   HDAC2↓, 1,   HDAC3↓, 1,   mTOR↓, 1,   PI3K↓, 1,   Piezo1↑, 1,   STAT3↓, 3,   p‑STAT3↓, 2,   TumCG↓, 2,   TumCG∅, 1,  

Migration ⓘ

E-cadherin↑, 1,   ER-α36↝, 1,   F-actin↑, 1,   Ki-67↓, 2,   MMP2↓, 1,   MMP9↓, 1,   PKA↓, 1,   TumCI↓, 3,   TumCMig↓, 1,   TumCP↓, 6,   TumMeta↑, 1,   Vim↓, 2,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature ⓘ

EGFR↓, 1,   VEGF↓, 1,  

Barriers & Transport ⓘ

GLUT1↓, 1,  

Immune & Inflammatory Signaling ⓘ

CD4+↑, 1,   COX2↓, 2,   COX2↑, 1,   IL17↓, 1,   IL6↓, 1,   Inflam↓, 1,   p‑JAK2↓, 1,   NF-kB↓, 4,   p‑p65↓, 1,   PD-L1↓, 2,   TNF-α↓, 2,  

Hormonal & Nuclear Receptors ⓘ

RANKL↓, 1,  

Drug Metabolism & Resistance ⓘ

ChemoSen↑, 4,   Dose∅, 1,   eff↓, 4,   eff↑, 7,   eff∅, 1,   RadioS↑, 1,   selectivity↑, 5,   TET2↑, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 1,   AST↓, 1,   EGFR↓, 1,   IL6↓, 1,   Ki-67↓, 2,   PD-L1↓, 2,  

Functional Outcomes ⓘ

TumVol↓, 4,  

Infection & Microbiome ⓘ

CD8+↑, 1,  
Total Targets: 122

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

HO-1↑, 1,   NRF2↑, 1,   ROS⇅, 1,  

Cell Death ⓘ

e-Akt↑, 1,  

Kinase & Signal Transduction ⓘ

AMPKα↑, 1,  

Transcription & Epigenetics ⓘ

tumCV↓, 1,   tumCV∅, 1,  

Proliferation, Differentiation & Cell State ⓘ

e-ERK↑, 1,  

Drug Metabolism & Resistance ⓘ

eff↓, 1,  

Functional Outcomes ⓘ

AntiDiabetic↑, 1,   hepatoP↑, 1,   toxicity↓, 2,  
Total Targets: 12

Scientific Paper Hit Count for: tumCV, Cell Viability
21 Silver-NanoParticles
15 Quercetin
14 Thymoquinone
12 Curcumin
12 Sulforaphane (mainly Broccoli)
10 Cisplatin
9 Honokiol
9 Phenethyl isothiocyanate
8 Betulinic acid
7 SonoDynamic Therapy UltraSound
7 Berberine
7 Capsaicin
7 Carvacrol
7 Magnetic Fields
7 Shikonin
6 Allicin (mainly Garlic)
6 Resveratrol
6 Fisetin
5 Radiotherapy/Radiation
5 Rosmarinic acid
4 Apigenin (mainly Parsley)
4 Metformin
4 Artemisinin
4 Baicalein
4 Berbamine
4 Biochanin A
4 Gemcitabine (Gemzar)
4 Caffeic Acid Phenethyl Ester (CAPE)
4 Emodin
4 Shilajit/Fulvic Acid
4 Graviola
4 Propolis -bee glue
4 Silymarin (Milk Thistle) silibinin
4 Vitamin C (Ascorbic Acid)
3 Ashwagandha(Withaferin A)
3 Astaxanthin
3 Carnosic acid
3 5-fluorouracil
3 chitosan
3 Selenium
3 Chrysin
3 Citric Acid
3 Gallic acid
3 Gambogic Acid
3 Magnolol
3 Hyperthermia
3 doxorubicin
3 Juglone
3 Lycopene
3 Methylene blue
3 Magnetic Field Rotating
3 Piperlongumine
3 Plumbagin
3 Parthenolide
3 Selenite (Sodium)
3 Urolithin
2 Alpha-Lipoic-Acid
2 Aloe anthraquinones
2 Bacopa monnieri
2 Boswellia (frankincense)
2 brusatol
2 Caffeic acid
2 Chlorogenic acid
2 Coenzyme Q10
2 Copper and Cu NanoParticles
2 Hydroxycinnamic-acid
2 Dichloroacetate
2 EGCG (Epigallocatechin Gallate)
2 Garcinol
2 Luteolin
2 Iron
2 Gold NanoParticles
2 Methylsulfonylmethane
2 Naringin
2 Nimbolide
2 Piperine
2 salinomycin
2 polyethylene glycol
2 Selenium NanoParticles
2 Chemotherapy
2 Photodynamic Therapy
2 Aflavin-3,3′-digallate
2 Ursolic acid
2 VitK3,menadione
2 Zerumbone
1 3-bromopyruvate
1 Resiquimod
1 Andrographis
1 Ascorbyl Palmitate
1 Trastuzumab
1 Melatonin
1 Atorvastatin
1 Bevacizumab (brand Avastin)
1 borneol
1 Boron
1 hydroxychloroquine
1 Catechins
1 Cannabidiol
1 Selenate
1 Vitamin E
1 Disulfiram
1 Ellagic acid
1 Electrical Pulses
1 Estrogen
1 Fucoidan
1 Ferulic acid
1 Ginkgo biloba
1 γ-linolenic acid (Borage Oil)
1 HydroxyCitric Acid
1 tamoxifen
1 HydroxyTyrosol
1 itraconazole
1 Folic Acid, Vit B9
1 immunotherapy
1 Mushroom Chaga
1 Bicarbonate(Sodium)
1 Niclosamide (Niclocide)
1 Oleuropein
1 Phenylbutyrate
1 Propyl gallate
1 Pterostilbene
1 Hyperoside
1 Perilla
1 Rutin
1 Scoulerine
1 acetazolamide
1 Vitamin D3
1 Vitamin K2
1 Whole Body Vibration
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:897  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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