Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
5487- EP,    High-frequency irreversible electroporation improves survival and immune cell infiltration in rodents with malignant gliomas
- in-vivo, GBM, NA
OS↑, CellMemb↑, Imm↑, Inflam↓, necrosis↑, Pyro↑, eff↑, IL2↑, IL6↑, IL17↑, IFN-γ↓,
5488- EP,    An in vivo study of a custom-made high-frequency irreversible electroporation generator on different tissues for clinically relevant ablation zones
- in-vivo, Nor, NA
*MusCon↓, *Dose↓, *eff↑, *Temp↝,
5489- EP,    Electroporation and cell killing by milli- to nanosecond pulses and avoiding neuromuscular stimulation in cancer ablation
- in-vitro, Colon, NA
eff↑, TumCD↑, MusCon↓, Temp↓, eff↑, eff↓, eff↑, eff∅, other↑,
5490- EP,    Application of Pulsed Electric Fields to Cancer Therapy
- Review, Var, NA
CellMemb↑, Ca+2↑, Imm↑, TumMeta↓,
5491- EP,    Nano-pulse stimulation™ therapy (NPS™) is superior to cryoablation in clearing murine melanoma tumors
- in-vivo, Melanoma, B16-F10
TumCD↑, eff↑, MusCon↓, CellMemb↑, ER Stress↑, other↝,
5492- EP,    Nano-Pulse Stimulation Therapy in Oncology
- in-vivo, PC, Panc02 - in-vivo, BC, 4T1
CellMemb↑, Ca+2↑, DNAdam↑, eff↝, Imm↑,
5493- EP,    Schottky nanodiodes array enabled triboelectric nanosecond pulse generator for ultralow-cost tumor therapy
- Review, Var, NA
other↝, other↝, Ca+2↑, TumCD↑, Imm↑, TumCG↓, other↓,
5494- EP,    An Overview of Subnanosecond Pulsed Electric Field Biological Effects: Toward Contactless Technologies for Cancer Treatment
- Review, Var, NA
other↝, ROS↑, Temp∅, CellMemb↑, Ca+2↑, Apoptosis↑, TumCD↑, MMP↓, necrosis↑, TumVol↓, Remission↑,
5495- EP,    Irreversible electroporation in focal therapy for prostate cancer: current status and future directions
- Review, Pca, NA
Ca+2↑, ATP↓, mtDam↑, ROS↑, CellMemb↑,
5519- EP,    Nanosecond Pulsed Electric Fields (nsPEFs) for Precision Intracellular Oncotherapy: Recent Advances and Emerging Directions
- Review, Var, NA
MMP↓, Ca+2↑, eff↑, ER Stress↑, selectivity↑, CSCs↓, CD44↓, CD133↓, ROS↑, Imm↑, DNAdam↑, MOMP↑, Cyt‑c↑, Casp9↑, Casp3↑, Casp9↑, TumCD↑, Fas↑, UPR↑, Dose↝, Dose↝, Dose↓, Dose↑, HMGB1↓, eff↑, EPR↑, ChemoSen↑, ETC↝, *AntiAge↑, *Hif1a↑, *SIRT1↑,
5520- EP,    Nanosecond Pulsed Electric Field (nsPEF): Opening the Biotechnological Pandora’s Box
- Review, Var, NA
Ca+2↑, Apoptosis↑, Diff↑, TumCP↓, Wound Healing↑, CellMemb↑, VGCC↑, VGSC↑, DNAdam↑, selectivity↑,
5521- EP,    Nanosecond Pulsed Electric Fields (nsPEFs) Modulate Electron Transport in the Plasma Membrane and the Mitochondria
- in-vitro, BC, 4T1 - in-vitro, Nor, H9c2
ETC↓, ROS↑, *mt-ROS↑,
5522- EP,    Nanosecond pulsed electric field suppresses growth and reduces multi-drug resistance effect in pancreatic cancer
- in-vitro, PC, NA
AntiCan↑, Dose↝, CellMemb↑, ChemoSen↑, MMP↓,
5523- EP,    Nanosecond pulsed electric field applications rejuvenate aging endothelial cells by rescuing mitochondrial-to-nuclear retrograde communication
- vitro+vivo, Nor, HUVECs
*MMP↑, *Hif1a↑, *SIRT1↑, *ROS↓, *AntiAge↑, *Dose↝, *angioG↑,
5524- EP,    Considerations for Exploring Nanosecond Pulsed Electric Fields (nsPEFs) for Treatments of Cancer, Benign Skin Diseases, Atrial Fibrillation, and for New Mechanistic Understandings
- Review, Var, NA
ETC↝,
6796- EPA,    Effect of eicosapentaenoic acid and other fatty acids on the growth in vitro of human pancreatic cancer cell lines
- in-vitro, PC, MIA PaCa-2 - in-vitro, Pca, PANC1
TumCG↓, eff↓, lipid-P↑, tumCV↓, ROS↑,
6795- EPA,    Necrosis and apoptosis in lymphoma cell lines exposed to eicosapentaenoic acid and antioxidants
- in-vitro, lymphoma, NA
ROS↑, Necroptosis↑,
6790- EPA,    Double-blind, placebo-controlled, randomized study of eicosapentaenoic acid diester in patients with cancer cachexia
- Trial, Lung, NA
*Dose↝, Weight↑, cachexia↓, OS∅,
6791- EPA,    An eicosapentaenoic acid supplement versus megestrol acetate versus both for patients with cancer-associated wasting: a North Central Cancer Treatment Group and National Cancer Institute of Canada collaborative effort
- vitro+vivo, Var, NA
Dose↝, Weight↑, eff↑, OS∅, QoL∅,
6792- EPA,    Effect of Eicosapentaenoic Acid on Body Composition and Inflammation Markers in Patients with Head and Neck Squamous Cell Cancer from a Public Hospital in Mexico
- Trial, HNSCC, NA
Dose↝, *IL1β↓, *IL6↓, *TNF-α↓, *IFN-γ↓, QoL↑,
6793- EPA,    Contribution of Pyk2 pathway and reactive oxygen species (ROS) to the anti-cancer effects of eicosapentaenoic acid (EPA) in PC3 prostate cancer cells
- in-vitro, Pca, PC3
tumCV↓, ERK↓, PTK2B / PYK2↓, TumCG↓, ROS↑, TumCMig↓, TumCI↓,
6794- EPA,    EPA, an omega-3 fatty acid, induces apoptosis in human pancreatic cancer cells: role of ROS accumulation, caspase-8 activation, and autophagy induction
- in-vitro, BC, NA - vitro+vivo, PC, MIA PaCa-2
ROS↑, Casp8↑, Apoptosis↑, ROS↑, TumCG↓, TumCD↑, eff↑,
6800- EPA,  DHA,    Anti-inflammatory effects of EPA and DHA are dependent upon time and dose-response elements associated with LPS stimulation in THP-1-derived macrophages
- in-vitro, Nor, THP1
*Inflam↓, NF-kB↓,
6799- EPA,    Inhibitory effects of eicosapentaenoic acid (EPA) on the hypoxia/reoxygenation-induced tyrosine kinase activation in cultured human umbilical vein endothelial cells
- in-vitro, Nor, HUVECs
*ROS↓,
6798- EPA,    Eicosapentaenoic acid attenuates cigarette smoke-induced lung inflammation by inhibiting ROS-sensitive inflammatory signaling
- Human, Nor, NA
*ROS↓, *antiOx↑, *Inflam↓, *NF-kB↓,
6797- EPA,    Effects of cellular redox balance on induction of apoptosis by eicosapentaenoic acid in HT29 colorectal adenocarcinoma cells and rat colon in vivo
- in-vivo, Colon, HT29
tumCV↓, Casp3↑, eff↓, eff↑, Apoptosis↑, ROS↑,
5046- erastin,  SAS,    The structure of erastin-bound xCT–4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis
- Study, Var, NA
xCT/SLC7A11↓, ROS↑, TumCG↓, GSH↓, Ferroptosis↑,
5047- erastin,    The ferroptosis inducer erastin irreversibly inhibits system xc− and synergizes with cisplatin to increase cisplatin’s cytotoxicity in cancer cells
- in-vitro, Ovarian, NA
xCT/SLC7A11↓, GSH↓, Ferroptosis↑, ChemoSen↑, eff↑,
5048- erastin,    How erastin assassinates cells by ferroptosis revealed
- Review, Var, NA
Ferroptosis↑, xCT/SLC7A11↓, lipid-P↑,
2455- erastin,    Discovery of the Inhibitor Targeting the SLC7A11/xCT Axis through In Silico and In Vitro Experiments
- in-vitro, Cerv, HeLa
xCT/SLC7A11↓, GSH↓, ROS↑, TumCMig↓,
2204- erastin,    Regulation of ferroptotic cancer cell death by GPX4
- in-vitro, fibroS, HT1080
GSH↓, Ferroptosis↑, ROS↑, GPx↓, GPx4↓, lipid-P↑, eff↓, eff↑,
975- Est,    Estrogen inhibits autophagy and promotes growth of endometrial cancer by promoting glutamine metabolism
- vitro+vivo, UEC, NA
GLS↑, cMyc↑, GlutMet↑, tumCV↑, TumAuto↓,
6429- ESTr,  FEO,    Can Estragole in Fennel Seed Decoctions Really Be Considered a Danger for Human Health? A Fennel Safety Update
- Review, Nor, NA
*toxicity↝,
6425- ESTr,    Assessing the Risk of Estragole Consumption From Natural Products in the Malaysian Market by Using the Margin of Exposure Approach
- Review, Nor, NA
*toxicity↑, *Dose↝,
6577- EU,    Eurycomanone suppresses expression of lung cancer cell tumor markers, prohibitin, annexin 1 and endoplasmic reticulum protein 28
- in-vitro, Lung, A549
Dose↝, TumCP↓, PHB↓, ANXA1↓, p38↓,
6574- EU,    Effects of Eurycoma longifolia Jack on chronic cerebral hypoperfusion-induced oxidative damage and memory deficit in rats
- in-vivo, Nor, NA
*cognitive↑, *antiOx↓, *MDA↓, *CRP↓, *neuroP↑, *Inflam↓,
6575- EU,    Eurycomanone from Eurycoma longifolia Jack upregulates neurotrophin-3 gene expression in retinal Müller cells in vitro
- in-vivo, Nor, NA
*Hypoxia↓, *NTF3/NT-3↑, *other↑, *Half-Life↓,
6576- EU,    Eurycomanone induce apoptosis in HepG2 cells via up-regulation of p53
- in-vitro, HCC, HepG2
TumCD↑, selectivity↑, Apoptosis↓, ChrMod↑, DNAdam↑, P53↑, BAX↑, Bcl-2↓, Cyt‑c↑, eff↑, TumCCA↑,
6587- EU,    Eurycoma longifolia, A Potential Phytomedicine for the Treatment of Cancer: Evidence of p53-mediated Apoptosis in Cancerous Cells
- in-vitro, Lung, A549 - in-vitro, BC, MCF7
AntiCan↑, Apoptosis↑, P53↑, BAX↑, Bcl-2↓, PHB↓, ANXA1↓, hnRNPA1↓,
6578- EU,    Eurycomanol and eurycomanone as potent inducers for cell-cycle arrest and apoptosis in small and large human lung cancer cell lines
- in-vitro, Lung, H460 - in-vitro, Lung, A549
Dose↝, selectivity↑, tumCV↓, TumCCA↓, Apoptosis↑,
6579- EU,    Eurycomanone and Eurycomanol from Eurycoma longifolia Jack as Regulators of Signaling Pathways Involved in Proliferation, Cell Death and Inflammation
- in-vitro, AML, K562
tumCV↓, TumCP↓, selectivity↑, NF-kB↓, IKKα↓, MAPK↓,
6580- EU,    Eurycomanone Blocks TGF-β1-Induced Epithelial-to-Mesenchymal Transition, Migration, and Invasion Pathways in Human Non-Small Cell Lung Cancer Cells by Targeting Smad and Non-Smad Signaling
- in-vitro, Lung, A549 - in-vitro, Lung, Calu-1
TumCMig↓, MMP2↓, EMT↓, E-cadherin↑, Akt↓, N-cadherin↓, TGF-β↓, Smad1↓,
6581- EU,    Bioavailability of Eurycomanone in Its Pure Form and in a Standardised Eurycoma longifolia Water Extract
- in-vitro, Colon, Caco-2 - in-vivo, Nor, NA
*Half-Life↓, *BioAv↝,
6582- EU,    Eurycoma longifolia (Jack) Improves Serum Total Testosterone in Men: A Systematic Review and Meta-Analysis of Clinical Trials
- Review, Nor, NA
*testos↑,
6583- EU,    Inactivation of AKT/NF-κB signaling by eurycomalactone decreases human NSCLC cell viability and improves the chemosensitivity to cisplatin
- in-vitro, NSCLC, A549 - in-vitro, NSCLC, Calu-1
tumCV↓, TumCCA↑, Casp3↑, PARP↑, Bcl-xL↓, survivin↓, Akt↓, NF-kB↓, ChemoSen↑,
6584- EU,    Eurycoma longifolia: an overview on the pharmacological properties for the treatment of common cancer
- Review, Var, NA
*AntiAge↑, *Inflam↓, *antiOx↑, TumCD↑, Bcl-2↓, cl‑Casp7↑, cl‑PARP↑, BAX↑, P53↑, tumCV↓, selectivity↑, *testos↑, *PSA∅,
6585- EU,    Anti-Tumor Activity of Eurycoma longifolia Root Extracts against K-562 Cell Line: In Vitro and In Vivo Study
- vitro+vivo, AML, K562
Dose↝, TumCG↓, Apoptosis↑, TumCCA↑, DNAdam↑, Akt↓, Bcl-2↓, PCNA↓,
6586- EU,    Unfermented Freeze-Dried Leaf Extract of Tongkat Ali (Eurycoma longifolia Jack.) Induced Cytotoxicity and Apoptosis in MDA-MB-231 and MCF-7 Breast Cancer Cell Lines
TumCD↑, DNAdam↑, TumCCA↑, Cyt‑c↑, Casp3↑,
6772- Eug,    Antimicrobial activity of eugenol and essential oils containing eugenol: A mechanistic viewpoint
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiBio↑, *Bacteria↓, *AntiFungal↑,
6384- Eug,    Eugenol modulates the NOD1-NF-κB signaling pathway via targeting NF-κB protein in triple-negative breast cancer cells
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-453
TumCG↓, TumMeta↓, NF-kB↓,

Showing Research Papers: 3601 to 3650 of 8269
Prev Page 73 of 166 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 8269

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

Ferroptosis↑, 4,   GPx↓, 1,   GPx4↓, 1,   GSH↓, 4,   lipid-P↑, 3,   ROS↑, 13,   xCT/SLC7A11↓, 4,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 1,   ETC↓, 1,   ETC↝, 2,   MMP↓, 3,   mtDam↑, 1,   PHB↓, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

cMyc↑, 1,   GLS↑, 1,   GlutMet↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 3,   Apoptosis↓, 1,   Apoptosis↑, 7,   BAX↑, 3,   Bcl-2↓, 4,   Bcl-xL↓, 1,   Casp3↑, 4,   cl‑Casp7↑, 1,   Casp8↑, 1,   Casp9↑, 2,   Cyt‑c↑, 3,   Fas↑, 1,   Ferroptosis↑, 4,   MAPK↓, 1,   MOMP↑, 1,   Necroptosis↑, 1,   necrosis↑, 2,   p38↓, 1,   Pyro↑, 1,   survivin↓, 1,   TumCD↑, 9,  

Transcription & Epigenetics(tgid=7) ⓘ

ChrMod↑, 1,   other↓, 1,   other↑, 1,   other↝, 4,   tumCV↓, 7,   tumCV↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↑, 2,   UPR↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

TumAuto↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 6,   P53↑, 3,   PARP↑, 1,   cl‑PARP↑, 1,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↓, 1,   TumCCA↑, 4,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD133↓, 1,   CD44↓, 1,   CSCs↓, 1,   Diff↑, 1,   EMT↓, 1,   ERK↓, 1,   TumCG↓, 7,   VGCC↑, 1,   VGSC↑, 1,  

Migration(tgid=13) ⓘ

Ca+2↑, 7,   E-cadherin↑, 1,   hnRNPA1↓, 1,   MMP2↓, 1,   N-cadherin↓, 1,   PTK2B / PYK2↓, 1,   Smad1↓, 1,   TGF-β↓, 1,   TumCI↓, 1,   TumCMig↓, 3,   TumCP↓, 3,   TumMeta↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

EPR↑, 1,  

Barriers & Transport(tgid=15) ⓘ

CellMemb↑, 8,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

ANXA1↓, 2,   HMGB1↓, 1,   IFN-γ↓, 1,   IKKα↓, 1,   IL17↑, 1,   IL2↑, 1,   IL6↑, 1,   Imm↑, 5,   Inflam↓, 1,   NF-kB↓, 4,  

Cellular Microenvironment(tgid=17) ⓘ

Temp↓, 1,   Temp∅, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ChemoSen↑, 4,   Dose↓, 1,   Dose↑, 1,   Dose↝, 8,   eff↓, 4,   eff↑, 13,   eff↝, 1,   eff∅, 1,   selectivity↑, 6,  

Clinical Biomarkers(tgid=22) ⓘ

IL6↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 2,   cachexia↓, 1,   MusCon↓, 2,   OS↑, 1,   OS∅, 2,   QoL↑, 1,   QoL∅, 1,   Remission↑, 1,   TumVol↓, 1,   Weight↑, 2,   Wound Healing↑, 1,  
Total Targets: 109

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 3,   MDA↓, 1,   ROS↓, 3,   mt-ROS↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

SIRT1↑, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   Hif1a↑, 2,   Hypoxia↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CRP↓, 1,   IFN-γ↓, 1,   IL1β↓, 1,   IL6↓, 1,   Inflam↓, 5,   NF-kB↓, 1,   NTF3/NT-3↑, 1,   PSA∅, 1,   TNF-α↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

Temp↝, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

testos↑, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↝, 1,   Dose↓, 1,   Dose↝, 3,   eff↑, 1,   Half-Life↓, 2,  

Clinical Biomarkers(tgid=22) ⓘ

CRP↓, 1,   IL6↓, 1,   PSA∅, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 3,   cognitive↑, 1,   MusCon↓, 1,   neuroP↑, 1,   toxicity↑, 1,   toxicity↝, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 1,   Bacteria↓, 1,  
Total Targets: 39

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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