Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
3717- FA,    Neuroprotective Properties of Ferulic Acid in Preclinical Models of Alzheimer's Disease: A Systematic Literature Review
- Review, AD, NA
*toxicity↓, *BBB↑, *Aβ↓, *antiOx↑, *Inflam↓, *neuroP↑,
3718- FA,    Therapeutic potential of ferulic acid and its derivatives in Alzheimer's disease-A systematic review
- Review, AD, NA
*antiOx↑, *ROS↓, *Inflam↓,
4059- FA,    Dietary B Vitamins and a 10-Year Risk of Dementia in Older Persons
- Study, AD, NA
*Risk↓, *cognitive↑,
4044- FA,    Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial
- Trial, AD, NA
*Hcy/homoC↓, *memory↑, *cognitive↑,
3783- FA,    Design, Synthesis, and Biological Evaluation of Ferulic Acid-Piperazine Derivatives Targeting Pathological Hallmarks of Alzheimer’s Disease
- NA, AD, NA
*ROS↓, *IronCh↑, *NLRP3↓, *Aβ↓, *AChE↓, *BChE↓, *antiOx↑, *BBB↑, *MMP↑, *memory↑, *SOD↑, *Catalase↑,
3782- FA,    Ferulic acid ameliorates bisphenol A (BPA)-induced Alzheimer’s disease-like pathology through Akt-ERK crosstalk pathway in male rats
- in-vivo, AD, NA
*cognitive↑, *ERK↓, *p‑Akt↓, *AChE↓, *BACE/β-secretase↓, *neuroP↑, *ROS↓, *MDA↓, *GSH↑, *GSSG↓, *p‑tau↓, *lipid-P↓, *Aβ↓,
3781- FA,    Therapeutic potential of ferulic acid and its derivatives in Alzheimer’s disease—A systematic review
- Review, AD, NA
*antiOx↑, *Inflam↓, *BBB↑, *AChE↓, *BChE↓,
3780- FA,    Ferulic Acid: A Natural Antioxidant with Application Towards Neuroprotection Against Alzheimer’s Disease
- Review, AD, NA
*antiOx↑, *SOD↑, *Catalase↑, *HO-1↑, *neuroP↑, *AChE↓, *MMP↑,
3779- FA,    A review on ferulic acid and analogs based scaffolds for the management of Alzheimer’s disease
- Review, AD, NA
*antiOx↑, *neuroP↑, *Aβ↓, *Inflam↓, *COX2/PTGS2↓, *Casp↓, *NOS2↓, *HO-1↑, *AChE∅, *BChE∅, *memory↑,
3778- FA,    Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer’s Disease: A Narrative Review
- Review, AD, NA
*neuroP↑, *Aβ↓, *antiOx↑, *Inflam↓, *ROS↓, *NF-kB↓, *NLRP3↓, *iNOS↓, *COX2/PTGS2↓, *TNF-α↓, *IL1β↓, *VCAM-1↓, *ICAM-1↓, *p‑MAPK?, *hepatoP↑, *TLR4↓, *PPARγ↑, *NRF2↑, *Fenton↓, *IronCh↑, *MDA↓, *HO-1↑, *Bil↑, *GCLC↑, *GCLM↑, *NQO1↑, *GutMicro↑, *SOD↑, *Ca+2↓, *lipid-P↓, *PGE2↓,
6872- FA,    Ferulic acid mitigated rotenone toxicity -Evoked Parkinson in rat model by featuring apoptosis, oxidative stress, and neuroinflammation signaling
- in-vivo, Park, NA
*Apoptosis↓, *neuroP↑,
6870- FA,    Folic acid supplementation improves cognitive function in participants with cerebral small vascular disease-related cognitive impairment: a randomized controlled trial
- Trial, AD, NA
*Dose↝, *cognitive↑, *Hcy/homoC↓, *MMP9↓, *Risk↓,
6871- FA,  Sesame,    Nano-encapsulated ferulic acid in sesame protein isolate alleviates acrylamide-induced liver toxicity and genotoxicity in rats via oxidative stress and DNA damage modulation
- in-vivo, Nor, NA
*GSH↑, *GPx↑, *SOD↓, *Catalase↑, *MDA↓, *IL6↓, *TNF-α↑, *DNAdam↓, *hepatoP↑, *BioAv↓, *BioAv↑,
6884- FA,    Effects of folic acid supplementation on cognitive function and Aβ-related biomarkers in mild cognitive impairment: a randomized controlled trial
- Trial, AD, NA
*cognitive↑, *Aβ↓, *BP↓, *SAM-e↓, *DNMT3A↑,
6868- FA,    Examination of the Bioavailability and Bioconversion of Wheat Bran-Bound Ferulic Acid: Insights into Gastrointestinal Processing and Colonic Metabolites
- in-vivo, Nor, NA
*BioAv↓,
6867- FA,  Ang,    Effect of Feru-guard 100M on amyloid-beta deposition in individuals with mild cognitive impairment
- Trial, AD, NA
*Aβ∅, *BrainVol∅, *cognitive∅,
6866- FA,  Ang,    Effects of Ferulic Acid and Angelica archangelica Extract (Feru-guard ®) on Mild Cognitive Impairment: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Prospective Trial
- Trial, AD, NA
*cognitive↑, *neuroP↑, *AChE↓, *Dose↝, *Aβ↓,
6865- FA,    Ferulic Acid Regulates GSDMD through the ROS/JNK/Bax Mitochondrial Apoptosis Pathway to Induce Pyroptosis in Lung Cancer
- in-vitro, Lung, NA
TumCP↓, MMP↓, LDH↑, Pyro↑, GSDMD↑, ROS↑, JNK↑, BAX↑,
6863- FA,  HCAs,    Absorption of hydroxycinnamates in humans after high-bran cereal consumption
- Human, Nor, NA
Dose↝,
6873- FA,    Ferulic acid: extraction, estimation, bioactivity and applications for human health and food
- Review, Nor, NA
*Inflam↓, *AntiBio↑, AntiCan↑, *AntiDiabetic↑, *cardioP↑, *neuroP↑, *ROS↓, *antiOx↑, *AGEs↓, *Catalase↑, *SOD↑,
6875- FA,    Ferulic Acid Improves Cognitive Skills Through the Activation of the Heme Oxygenase System in the Rat
- in-vivo, AD, NA
*HO-1↑, *memory↑, *cognitive↑,
6877- FA,    The protective role of ferulic acid on sepsis-induced oxidative damage in Wistar albino rats
- in-vivo, Nor, NA
*antiOx↑, *Inflam↓, *AntiCan↑, *hepatoP↑, *DNAdam↓, *Sepsis↓, *MDA↓, *GSH↑, *GPx↑, *ROS↓,
6878- FA,    Ferulic acid modulates fluoride-induced oxidative hepatotoxicity in male Wistar rats
- in-vivo, Nor, NA
*lipid-P↓, *hepatoP↑,
6881- FA,    Potential Therapeutic Efficacy of Ferulic Acid and Its Derivatives in the Management of Cancers: A Comprehensive Analysis With Mechanistic Insight
- Review, Var, NA
ROS↑, TumCCA↑, TumCI↓, TumCMig↓, TumCP↓, BioAv↑, BioAv↑, TP53↑, CDK2↓, CDK4↓, CDK6↓, JAK2↓, STAT6↓, tyrosinase↓, p‑Akt↓, p‑PI3K↓, mTOR↓, Ki-67↓, Casp3↑, proCasp8↑, cl‑PARP↑, BAX↑, Bcl-2↓, Mcl-1↓, MMP9↓, cycD1/CCND1↓, cycE/CCNE↓, PINK1↑, PARK2↑, MMP↓, CycD3↓, TumAuto⇅, eff↑, eff↑, ALAT↓, AST↓, ALP↓, VEGF↓, MMPs↓, angioG↓,
6882- FA,    Short- and long-term effects of ferulic acid on blood pressure in spontaneously hypertensive rats
- in-vivo, Nor, NA
*BP↓, *Dose↝,
6886- FA,  MTX,    Ferulic acid prevents oxidative stress, inflammation, and liver injury via upregulation of Nrf2/HO-1 signaling in methotrexate-induced rats
- in-vivo, Nor, NA
*hepatoP↑, *ROS↓, *TNF-α↓, *IL1β↓, *NF-kB↓, *p65↓, *BAX↓, *Casp3↓, *NRF2↑, *HO-1↑, *PPARγ↑, *Inflam↓,
6885- FA,    Mitigation of renal toxicity induced by paraquat using ferulic acid: Role of inflammatory pathways
- in-vivo, Nor, NA
*Dose↝, *TAC↑, *MDA↓, *RenoP↑, *PI3K↓, *Akt↓, *ROS↓, *Inflam↓, PPARγ↝, *NF-kB↓, *IL6↓, *TNF-α↓, *iNOS↓, *ALAT↓, *AST↓, *Urea↓, *Catalase↑, *SOD↑, *GPx↑, *GSH↑,
6883- FA,  Ang,    Effect of ferulic acid and Angelica archangelica extract on behavioral and psychological symptoms of dementia in frontotemporal lobar degeneration and dementia with Lewy bodies
- Trial, AD, NA
*Dose↝, *neuroP↑,
6962- FA,  VitB12,    Effects of Folic Acid and Vitamin B12, Alone and in Combination on Cognitive Function and Inflammatory Factors in the Elderly with Mild Cognitive Impairment: A Single-blind Experimental Design
- Trial, AD, NA
*Hcy/homoC↝, *IL6↓, *TNF-α↓, *MCP1/CCL2↝, *eff↑, *cognitive↑, *Inflam↓,
6952- FA,    Knowledge gaps in understanding the metabolic and clinical effects of excess folates/folic acid: a summary, and perspectives, from an NIH workshop
- Review, AD, NA
*other↝, *other↝, *Dose↑, *Dose↝, *Risk↓, *cognitive↑, *toxicity↝,
6951- FA,    Folic acid supplementation improves cognitive function by reducing the levels of peripheral inflammatory cytokines in elderly Chinese subjects with MCI
- Trial, AD, NA
*Dose↝, *cognitive↑, *Hcy/homoC↓, *IL6↓, *TNF-α↓,
6950- FA,  VitB12,    Effects of Folic Acid and Vitamin B12 Supplementation on Cognitive Impairment and Inflammation in Patients with Alzheimer's Disease: A Randomized, Single-Blinded, Placebo-Controlled Trial
- Trial, AD, NA
*Dose↝, *cognitive?,
6949- FA,  VitB12,    A controlled trial of homocysteine lowering and cognitive performance
- Trial, AD, NA
*Hcy/homoC↓, *cognitive∅,
6948- FA,  VitB12,    A randomized placebo controlled trial of homocysteine lowering to reduce cognitive decline in older demented people
- Trial, AD, NA
*Dose↝, *Hcy/homoC↓, *cognitive∅,
6947- FA,    Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial
- Trial, AD, NA
*Hcy/homoC↓, *cognitive↑,
6946- FA,    Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: Meta-analysis of 8 randomized trials involving 37 485 individuals
- Review, Var, NA
Hcy/homoC↓, Risk∅, toxicity↓,
6945- FA,    Folic acid supplementation and cancer risk: a meta-analysis of randomized controlled trials
- Review, Var, NA
Risk∅,
6944- FA,    Effects of folic acid supplementation on overall and site-specific cancer incidence during the randomised trials: meta-analyses of data on 50,000 individuals
- Review, Var, NA
Risk∅,
6953- FA,    Folic Acid Supplementation and Risk of Gestational Diabetes Mellitus: A Systematic Review of the Literature
- Review, Diabetic, NA
*Risk↑, *Risk↑, Dose↝, neuroP↑,
6954- FA,    Folic acid as a potential therapeutic agent for Alzheimer's disease: Effects on inflammatory cytokines, amyloid deposition, and neurotransmitter metabolism
- Trial, AD, NA
*Inflam↓, *Aβ↓, *IL1β↓, *IL6↓, *TNF-α↓, *tau↓, *GABA↑, *5HT↑, *Ach↑, *Albumin↑, *HemoG↑, *neuroP↑, *Hcy/homoC↓,
6955- FA,    Women Taking a Folic Acid Supplement in Countries with Mandatory Food Fortification Programs May Be Exceeding the Upper Tolerable Limit of Folic Acid: A Systematic Review
- Review, Nor, NA
toxicity↑, *Dose↝, *Dose↝,
6956- FA,  VitB12,    A randomized placebo-controlled trial of using B vitamins to prevent cognitive decline in older mild cognitive impairment patients
- Trial, AD, NA
*Dose↝, *Hcy/homoC↓, *cognitive↑, *eff↓,
6957- FA,    Folic Acid Supplementation May Reduce Colorectal Cancer Risk in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis
- Review, CRC, NA
Risk↓,
6958- FA,    Folate intake and breast cancer prognosis: a meta-analysis of prospective observational studies
- Review, BC, NA
OS↑,
6959- FA,    Folate intake and pancreatic cancer risk: an overall and dose-response meta-analysis
- Review, PC, NA
Risk↓,
6960- FA,  VitA,RetA,  VitC,  VitD3,  VitE  Dietary supplement use and colorectal cancer risk: a systematic review and meta-analyses of prospective cohort studies
- Review, CRC, NA
Risk∅, eff↑,
6961- FA,  VitB12,  VitB6,  Silicon,  Alum  B Vitamins Prevent Iron-Associated Brain Atrophy and Domain-Specific Effects of Iron, Copper, Aluminum, and Silicon on Cognition in Mild Cognitive Impairment
- Trial, AD, NA
*BrainVol↝, *cognitive↝, *cognitive↑, *Dose↝, *other↝, *Hcy/homoC↓, *Risk↓, *BrainVol∅, *BrainVol↑, *other↝, *cognitive↑, *cognitive↑, *other↝, *Risk↝,
1623- FA,    Folic acid: friend or foe in cancer therapy
- Review, Var, NA
Risk↝,
1622- FA,    Folate and Its Impact on Cancer Risk
- Review, NA, NA
eff↓,
1654- FA,    Molecular mechanism of ferulic acid and its derivatives in tumor progression
- Review, Var, NA
AntiCan↑, Inflam↓, RadioS↑, ROS↑, Apoptosis↑, TumCCA↑, TumCMig↑, TumCI↓, angioG↓, ChemoSen↑, ChemoSideEff↓, P53↑, cycD1/CCND1↓, CDK4↓, CDK6↓, TumW↓, miR-34a↑, Bcl-2↓, Casp3↑, BAX↑, β-catenin/ZEB1↓, cMyc↓, Bax:Bcl2↑, SOD↓, GSH↓, LDH↓, ERK↑, eff↑, JAK2↓, STAT6↓, NF-kB↓, PYCR1↓, PI3K↓, Akt↓, mTOR↓, Ki-67↓, VEGF↓, FGFR1↓, EMT↓, CAIX/CA9↓, LC3II↑, p62↑, PKM2↓, Glycolysis↓, *BioAv↓,

Showing Research Papers: 3751 to 3800 of 8269
Prev Page 76 of 166 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 8269

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

GSH↓, 1,   PARK2↑, 1,   PYCR1↓, 1,   ROS↑, 3,   SOD↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

FGFR1↓, 1,   MMP↓, 2,   PINK1↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,   CAIX/CA9↓, 1,   cMyc↓, 1,   Glycolysis↓, 1,   LDH↓, 1,   LDH↑, 1,   PKM2↓, 1,   PPARγ↝, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   p‑Akt↓, 1,   Apoptosis↑, 1,   BAX↑, 3,   Bax:Bcl2↑, 1,   Bcl-2↓, 2,   Casp3↑, 2,   proCasp8↑, 1,   GSDMD↑, 1,   JNK↑, 1,   Mcl-1↓, 1,   Pyro↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

LC3II↑, 1,   p62↑, 1,   TumAuto⇅, 1,  

DNA Damage & Repair(tgid=10) ⓘ

P53↑, 1,   cl‑PARP↑, 1,   TP53↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 2,   cycD1/CCND1↓, 2,   CycD3↓, 1,   cycE/CCNE↓, 1,   TumCCA↑, 2,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

EMT↓, 1,   ERK↑, 1,   miR-34a↑, 1,   mTOR↓, 2,   PI3K↓, 1,   p‑PI3K↓, 1,   STAT6↓, 2,   tyrosinase↓, 1,  

Migration(tgid=13) ⓘ

Ki-67↓, 2,   MMP9↓, 1,   MMPs↓, 1,   TumCI↓, 2,   TumCMig↓, 1,   TumCMig↑, 1,   TumCP↓, 2,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 2,   VEGF↓, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Inflam↓, 1,   JAK2↓, 2,   NF-kB↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CDK6↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 2,   ChemoSen↑, 1,   Dose↝, 2,   eff↓, 1,   eff↑, 4,   RadioS↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   ALP↓, 1,   AST↓, 1,   Hcy/homoC↓, 1,   Ki-67↓, 2,   LDH↓, 1,   LDH↑, 1,   TP53↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 2,   ChemoSideEff↓, 1,   neuroP↑, 1,   OS↑, 1,   Risk↓, 2,   Risk↝, 1,   Risk∅, 4,   toxicity↓, 1,   toxicity↑, 1,   TumW↓, 1,  
Total Targets: 86

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 9,   Bil↑, 1,   Catalase↑, 5,   Fenton↓, 1,   GCLC↑, 1,   GCLM↑, 1,   GPx↑, 3,   GSH↑, 4,   GSSG↓, 1,   HO-1↑, 5,   lipid-P↓, 3,   MDA↓, 5,   NQO1↑, 1,   NRF2↑, 2,   ROS↓, 8,   SAM-e↓, 1,   SOD↓, 1,   SOD↑, 5,   TAC↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,   PPARγ↑, 2,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   p‑Akt↓, 1,   Apoptosis↓, 1,   BAX↓, 1,   Casp↓, 1,   Casp3↓, 1,   iNOS↓, 2,   p‑MAPK?, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ach↑, 1,   other↝, 5,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 2,   DNMT3A↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↓, 1,   PI3K↓, 1,  

Migration(tgid=13) ⓘ

Ca+2↓, 1,   MMP9↓, 1,   VCAM-1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 3,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 2,   ICAM-1↓, 1,   IL1β↓, 3,   IL6↓, 5,   Inflam↓, 11,   MCP1/CCL2↝, 1,   NF-kB↓, 3,   p65↓, 1,   PGE2↓, 1,   TLR4↓, 1,   TNF-α↓, 6,   TNF-α↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   AChE↓, 5,   AChE∅, 1,   BChE↓, 2,   BChE∅, 1,   BrainVol↑, 1,   BrainVol↝, 1,   BrainVol∅, 2,   GABA↑, 1,   tau↓, 1,   p‑tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 1,   Aβ↓, 8,   Aβ∅, 1,   BACE/β-secretase↓, 1,   NLRP3↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 3,   BioAv↑, 1,   Dose↑, 1,   Dose↝, 13,   eff↓, 1,   eff↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   Albumin↑, 1,   AST↓, 1,   Bil↑, 1,   BP↓, 2,   GutMicro↑, 1,   Hcy/homoC↓, 9,   Hcy/homoC↝, 1,   HemoG↑, 1,   IL6↓, 5,   NOS2↓, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiDiabetic↑, 1,   cardioP↑, 1,   cognitive?, 1,   cognitive↑, 15,   cognitive↝, 1,   cognitive∅, 3,   hepatoP↑, 5,   memory↑, 4,   neuroP↑, 10,   RenoP↑, 1,   Risk↓, 4,   Risk↑, 2,   Risk↝, 1,   toxicity↓, 1,   toxicity↝, 1,  

Infection & Microbiome(tgid=24) ⓘ

Sepsis↓, 1,  
Total Targets: 105

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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