Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
312- AgNPs,  wortm,    Inhibition of autophagy enhances the anticancer activity of silver nanoparticles
- vitro+vivo, Cerv, HeLa
APA↑, p62↓, PIK3CA↑, TumVol↓, TumAuto↑, eff↑,
309- AgNPs,    Interference of silver, gold, and iron oxide nanoparticles on epidermal growth factor signal transduction in epithelial cells
- in-vitro, NA, A431
ROS↑, Akt↓, p‑ERK↓,
306- AgNPs,    Cancer Therapy by Silver Nanoparticles: Fiction or Reality?
- Analysis, NA, NA
EPR↝, ROS↑, IL1↑, IL8↑, ER Stress↑, MMP9↑, MMP↓, Cyt‑c↑, Apoptosis↑, Hif1a↑, BBB↑, GutMicro↝, eff↑, eff↑, RadioS↑,
305- AgNPs,    Activity and pharmacology of homemade silver nanoparticles in refractory metastatic head and neck squamous cell cancer
- Case Report, HNSCC, NA
OS↑, Dose↓, BioAv↝, toxicity↓, Remission↑, other↝, other↝, other↝, Dose↝, BioAv↝,
345- AgNPs,    Antitumor activity of silver nanoparticles in Dalton’s lymphoma ascites tumor model
- vitro+vivo, lymphoma, NA
OS↑, ascitic↓,
344- AgNPs,    Cytotoxicity and ROS production of manufactured silver nanoparticles of different sizes in hepatoma and leukemia cells
- in-vitro, Liver, HepG2
ROS↑, GSH↓,
374- AgNPs,    Silver nanoparticles selectively treat triple‐negative breast cancer cells without affecting non‐malignant breast epithelial cells in vitro and in vivo
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231 - in-vivo, NA, NA
ER Stress↑, DNAdam↑, ROS↑, Apoptosis↑, GSH/GSSG↓, NADPH/NADP+↓, TumCG↓, UPR↑,
373- AgNPs,    Cytotoxic Potential and Molecular Pathway Analysis of Silver Nanoparticles in Human Colon Cancer Cells HCT116
- in-vitro, Colon, HCT116
LDH↓, ROS↑, MDA↑, ATP↓, GSH↓, MMP↓,
372- AgNPs,    Investigating oxidative stress and inflammatory responses elicited by silver nanoparticles using high-throughput reporter genes in HepG2 cells: effect of size, surface coating, and intracellular uptake
- in-vitro, Hepat, HepG2
NRF2↑, GSH↓,
371- AgNPs,    Cytotoxicity and genotoxicity of silver nanoparticles in the human lung cancer cell line, A549
- in-vitro, Lung, A549
ROS↑, mtDam↑,
370- AgNPs,    Differential genotoxicity mechanisms of silver nanoparticles and silver ions
- in-vitro, lymphoma, TK6
ROS↑,
369- AgNPs,    Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis
- in-vitro, Liver, NA
ROS↑, GSH↓, DNAdam↑, lipid-P↝, Apoptosis↑, BAX↑, Bcl-2↓, MMP↓, Casp9↑, Casp3↑, JNK↑,
368- AgNPs,    In vitro evaluation of silver nanoparticles on human tumoral and normal cells
- in-vitro, Var, NA
mtDam↑, LDH↓,
367- AgNPs,    Presence of an Immune System Increases Anti-Tumor Effect of Ag Nanoparticle Treated Mice
- in-vivo, NA, NA
ROS↑, mtDam↑, TumCG↓,
366- AgNPs,    Silver nanoparticles inhibit the function of hypoxia-inducible factor-1 and target genes: insight into the cytotoxicity and antiangiogenesis
- in-vitro, BC, MCF7
HIF-1↓, Hif1a↓, VEGF↓, GLUT1↓,
365- AgNPs,    Silver nanoparticles affect glucose metabolism in hepatoma cells through production of reactive oxygen species
- in-vitro, Hepat, HepG2
ROS↑, GlucoseCon↓, TumCD↑, NRF2↓,
364- AgNPs,    Differential Action of Silver Nanoparticles on ABCB1 (MDR1) and ABCC1 (MRP1) Activity in Mammalian Cell Lines
- in-vitro, Lung, A549 - in-vitro, Hepat, HepG2 - in-vitro, CRC, SW-620
TumCD↑,
363- AgNPs,    Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis
ROS↑, lipid-P↑, Apoptosis↑, BAX↑, Bcl-2↓, MMP↓, Cyt‑c↑, Casp3↑, Casp9↑, JNK↑,
362- AgNPs,    Comparative and Mechanistic Study on the Anticancer Activity of Quinacrine-Based Silver and Gold Hybrid Nanoparticles in Head and Neck Cancer
- vitro+vivo, SCC, SCC9
DNAdam↑, TumVol↓,
361- AgNPs,    Annona muricata assisted biogenic synthesis of silver nanoparticles regulates cell cycle arrest in NSCLC cell lines
- in-vitro, Lung, A549
Apoptosis↑, Casp↑, TumCCA↑,
359- AgNPs,    Anti-cancer & anti-metastasis properties of bioorganic-capped silver nanoparticles fabricated from Juniperus chinensis extract against lung cancer cells
- in-vitro, Lung, A549 - in-vitro, Nor, HEK293
Casp3↑, Casp9↑, P53↑, ROS↑, MMP2↓, MMP9↓, TumCCA↑, *toxicity↓, TumCMig↓, TumCI↓,
346- AgNPs,  RSQ,    Investigating Silver Nanoparticles and Resiquimod as a Local Melanoma Treatment
- in-vivo, Melanoma, SK-MEL-28 - in-vivo, Melanoma, WM35
ROS↑, Ca+2↝, Casp3↑, Casp8↑, Casp9↑, CD4+↑, CD8+↑, tumCV↓, eff↓, *toxicity↓,
347- AgNPs,    The Role of Silver Nanoparticles in the Diagnosis and Treatment of Cancer: Are There Any Perspectives for the Future?
- Review, NA, NA
ROS↑, Apoptosis↑, ER Stress↑,
348- AgNPs,    Induction of p53 mediated mitochondrial apoptosis and cell cycle arrest in human breast cancer cells by plant mediated synthesis of silver nanoparticles from Bergenia ligulata (Whole plant)
- in-vitro, BC, MCF7
Apoptosis↑, ROS↑, MMP↓, P53↑, BAX↑, cl‑Casp3↑,
349- AgNPs,    Insight into the molecular mechanism, cytotoxic, and anticancer activities of phyto-reduced silver nanoparticles in MCF-7 breast cancer cell lines
- in-vitro, BC, MCF7
Apoptosis↑, ROS↑, CellMemb↑,
350- AgNPs,    Cytotoxic and Apoptotic Effects of Green Synthesized Silver Nanoparticles via Reactive Oxygen Species-Mediated Mitochondrial Pathway in Human Breast Cancer Cells
- in-vitro, BC, MCF7
ROS↑, MMP↓, P53↑, BAX↑, Casp3↑, Casp9↑, Bcl-2↓,
351- AgNPs,    Study of antitumor activity in breast cell lines using silver nanoparticles produced by yeast
- in-vitro, BC, MCF7 - in-vitro, BC, T47D
Casp9↑, Casp3↑, Casp7↑, Bcl-2↓,
352- AgNPs,    Synthesis of silver nanoparticles (Ag NPs) for anticancer activities (MCF 7 breast and A549 lung cell lines) of the crude extract of Syzygium aromaticum
- in-vitro, BC, MCF7
TumCD↑,
354- AgNPs,    Silver nanoparticles induce SH-SY5Y cell apoptosis via endoplasmic reticulum- and mitochondrial pathways that lengthen endoplasmic reticulum-mitochondria contact sites and alter inositol-3-phosphate receptor function
- in-vitro, neuroblastoma, SH-SY5Y
TumCD↑, ER Stress↑, GRP78/BiP↑, p‑PERK↑, CHOP/DDIT3↑, Ca+2↑, XBP-1↑, p‑IRE1↑,
355- AgNPs,    Cytotoxicity and Genotoxicity of Biogenic Silver Nanoparticles in A549 and BEAS-2B Cell Lines
- in-vitro, Lung, A549 - in-vitro, NA, BEAS-2B
ROS↑, DNAdam↑, Apoptosis↑,
356- AgNPs,  MF,    Anticancer and antibacterial potentials induced post short-term exposure to electromagnetic field and silver nanoparticles and related pathological and genetic alterations: in vitro study
- in-vitro, BC, MCF7 - in-vitro, Bladder, HTB-22
Apoptosis↑, P53↑, iNOS↑, NF-kB↑, Bcl-2↓, ROS↑, SOD↑, TumCCA↑, eff↑, Catalase↑, other↑,
357- AgNPs,    Hypoxia-mediated autophagic flux inhibits silver nanoparticle-triggered apoptosis in human lung cancer cells
- in-vitro, Lung, A549 - in-vitro, Lung, L132
mtDam↑, ROS↑, Hif1a↑, LC3s↑, p62↑, eff↓,
358- AgNPs,    Preparation of triangular silver nanoparticles and their biological effects in the treatment of ovarian cancer
- vitro+vivo, Ovarian, SKOV3
TumCCA↑, ROS↑, Casp3↑, TumCG↓, cycD1/CCND1↓,
360- AgNPs,  Moringa,    Cytotoxic and Genotoxic Evaluation of Biosynthesized Silver Nanoparticles Using Moringa oleifera on MCF-7 and HUVEC Cell Lines
- in-vitro, BC, MCF7 - in-vitro, BC, HUVECs
DNAdam↑,
353- AgNPs,    The mechanism of cell death induced by silver nanoparticles is distinct from silver cations
- in-vitro, BC, SUM159
lipid-P↑, H2O2↑, ROS↑, Apoptosis↑,
377- AgNPs,    Anticancer Action of Silver Nanoparticles in SKBR3 Breast Cancer Cells through Promotion of Oxidative Stress and Apoptosis
- in-vitro, BC, SkBr3
ROS↑, Apoptosis↑, Bax:Bcl2↑, VEGF↑, Akt↓, PI3K↓, TAC↓, TOS↑, OSI↑, MDA↑, Casp3↑, Casp7↑,
403- AgNPs,  RF,    Synergetic effects of silver and gold nanoparticles in the presence of radiofrequency radiation on human kidney cells
- in-vitro, NA, HNK
Apoptosis↝,
402- AgNPs,  MF,    Anticancer and antibacterial potentials induced post short-term exposure to electromagnetic field and silver nanoparticles and related pathological and genetic alterations: in vitro study
- in-vitro, BC, MCF7
P53↑, iNOS↑, NF-kB↑, Bcl-2↓, miR-125b↓, ROS↑, SOD↑,
376- AgNPs,    Antitumor activity of colloidal silver on MCF-7 human breast cancer cells
- in-vitro, BC, MCF7
Apoptosis↑, LDH↓, SOD↑, DNAdam↑,
400- AgNPs,  MF,    Polyvinyl Alcohol Capped Silver Nanostructures for Fortified Apoptotic Potential Against Human Laryngeal Carcinoma Cells Hep-2 Using Extremely-Low Frequency Electromagnetic Field
- in-vitro, Laryn, HEp2
TumCP↓, Casp3↑, P53↑, Beclin-1/ATG6↑, TumAuto↑, GSR↑, ROS↑, MDA↑, ROS↑, SIRT1↑, Ca+2↑, Endon↑, DNAdam↑, Apoptosis↑, NF-kB↓,
399- AgNPs,  SIL,    Cytotoxic potentials of silibinin assisted silver nanoparticles on human colorectal HT-29 cancer cells
- in-vitro, CRC, HT-29
P53↑,
398- AgNPs,    Silver nanoparticles induced testicular damage targeting NQO1 and APE1 dysregulation, apoptosis via Bax/Bcl-2 pathway, fibrosis via TGF-β/α-SMA upregulation in rats
- in-vivo, Testi, NA
Bcl-2↓, Casp3↑, GSH↓, MDA↑, NO↑, H2O2↑, SOD↓,
397- AgNPs,  GEM,    Silver nanoparticles enhance the apoptotic potential of gemcitabine in human ovarian cancer cells: combination therapy for effective cancer treatment
- in-vitro, Ovarian, A2780S
P53↑, P21↑, BAX↑, Bak↑, Cyt‑c↑, Casp3↑, Casp9↑, Bcl-2↓, ROS↑, MMP↓,
396- AgNPs,    Systemic Evaluation of Mechanism of Cytotoxicity in Human Colon Cancer HCT-116 Cells of Silver Nanoparticles Synthesized Using Marine Algae Ulva lactuca Extract
- in-vitro, Colon, HCT116
P53↑, BAX↑, P21↑, Bcl-2↓,
395- AgNPs,    The apoptotic and genomic studies on A549 cell line induced by silver nitrate
- in-vitro, Lung, A549
BAX↑, MMP↓,
394- AgNPs,    Anticancer activity of Moringa oleifera mediated silver nanoparticles on human cervical carcinoma cells by apoptosis induction
- in-vitro, Cerv, HeLa
ROS↑,
393- AgNPs,    Green synthesized plant-based silver nanoparticles: therapeutic prospective for anticancer and antiviral activity
- in-vitro, NA, HCT116
mtDam↑, ROS↑, TumCCA↑, Casp3↑, BAX↑, Bcl-2↓, P53↑,
392- AgNPs,    Biogenic silver nanoparticles synthesized from Piper longum fruit extract inhibit HIF-1α/VEGF mediated angiogenesis in prostate cancer cells
VEGF↓, HIF-1↓,
391- AgNPs,    Silver nanoparticles inhibit VEGF-and IL-1β-induced vascular permeability via Src dependent pathway in porcine retinal endothelial cells
- in-vitro, Nor, NA
*VEGF↓, *IL1↓, toxicity↝, other↝,
389- AgNPs,  Citrate,    Silver Citrate Nanoparticles Inhibit PMA-Induced TNFα Expression via Deactivation of NF-κB Activity in Human Cancer Cell-Lines, MCF-7
- in-vitro, BC, MCF7
TNF-α↓, NF-kB↓,

Showing Research Papers: 351 to 400 of 8263
Prev Page 8 of 166 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 8263

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1)

Catalase↑, 1,   GSH↓, 5,   GSH/GSSG↓, 1,   GSR↑, 1,   H2O2↑, 2,   lipid-P↑, 2,   lipid-P↝, 1,   MDA↑, 4,   NADPH/NADP+↓, 1,   NRF2↓, 1,   NRF2↑, 1,   OSI↑, 1,   ROS↑, 29,   SOD↓, 1,   SOD↑, 3,   TAC↓, 1,   TOS↑, 1,  

Mitochondria & Bioenergetics(tgid=3)

ATP↓, 1,   MMP↓, 8,   mtDam↑, 5,  

Core Metabolism/Glycolysis(tgid=4)

GlucoseCon↓, 1,   LDH↓, 3,   PIK3CA↑, 1,   SIRT1↑, 1,  

Cell Death(tgid=5)

Akt↓, 2,   Apoptosis↑, 14,   Apoptosis↝, 1,   Bak↑, 1,   BAX↑, 8,   Bax:Bcl2↑, 1,   Bcl-2↓, 10,   Casp↑, 1,   Casp3↑, 12,   cl‑Casp3↑, 1,   Casp7↑, 2,   Casp8↑, 1,   Casp9↑, 7,   Cyt‑c↑, 3,   Endon↑, 1,   iNOS↑, 2,   JNK↑, 2,   TumCD↑, 4,  

Transcription & Epigenetics(tgid=7)

other↑, 1,   other↝, 4,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8)

CHOP/DDIT3↑, 1,   ER Stress↑, 4,   GRP78/BiP↑, 1,   p‑IRE1↑, 1,   p‑PERK↑, 1,   UPR↑, 1,   XBP-1↑, 1,  

Autophagy & Lysosomes(tgid=9)

APA↑, 1,   Beclin-1/ATG6↑, 1,   LC3s↑, 1,   p62↓, 1,   p62↑, 1,   TumAuto↑, 2,  

DNA Damage & Repair(tgid=10)

DNAdam↑, 7,   P53↑, 10,  

Cell Cycle & Senescence(tgid=11)

cycD1/CCND1↓, 1,   P21↑, 2,   TumCCA↑, 5,  

Proliferation, Differentiation & Cell State(tgid=12)

p‑ERK↓, 1,   miR-125b↓, 1,   PI3K↓, 1,   TumCG↓, 3,  

Migration(tgid=13)

Ca+2↑, 2,   Ca+2↝, 1,   MMP2↓, 1,   MMP9↓, 1,   MMP9↑, 1,   TumCI↓, 1,   TumCMig↓, 1,   TumCP↓, 1,  

Angiogenesis & Vasculature(tgid=14)

EPR↝, 1,   HIF-1↓, 2,   Hif1a↓, 1,   Hif1a↑, 2,   NO↑, 1,   VEGF↓, 2,   VEGF↑, 1,  

Barriers & Transport(tgid=15)

BBB↑, 1,   CellMemb↑, 1,   GLUT1↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

CD4+↑, 1,   IL1↑, 1,   IL8↑, 1,   NF-kB↓, 2,   NF-kB↑, 2,   TNF-α↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↝, 2,   Dose↓, 1,   Dose↝, 1,   eff↓, 2,   eff↑, 4,   RadioS↑, 1,  

Clinical Biomarkers(tgid=22)

ascitic↓, 1,   GutMicro↝, 1,   LDH↓, 3,  

Functional Outcomes(tgid=23)

OS↑, 2,   Remission↑, 1,   toxicity↓, 1,   toxicity↝, 1,   TumVol↓, 2,  

Infection & Microbiome(tgid=24)

CD8+↑, 1,  
Total Targets: 106

Pathway results for Effect on Normal Cells:


Angiogenesis & Vasculature(tgid=14)

VEGF↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

IL1↓, 1,  

Functional Outcomes(tgid=23)

toxicity↓, 2,  
Total Targets: 3

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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