Dose Cancer Research Results

Dose, Dosage: Click to Expand ⟱
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Drug dosage vs efficacy, and actual dosage number of research papers.
Scientific Papers found: Click to Expand⟱
4914- DSF,  immuno,    Disulfiram and cancer immunotherapy: Advanced nano-delivery systems and potential therapeutic strategies
- Review, Var, NA
AntiTum↑, eff↑, ALDH↓, Dose↝, RadioS↑, angioG↓, TumMeta↓, BioAv↝, ROS↑, DNAdam↑, P-gp/ABCB1↓, CSCs↓, EMT↓, Imm↑, SOD↓, MAPK↓, NF-kB↓, ChemoSen↑, eff↑, toxicity↝, BioAv↑, *Inflam↓, Sepsis↓,
4916- DSF,  Cu,    The immunomodulatory function and antitumor effect of disulfiram: paving the way for novel cancer therapeutics
- Review, Var, NA
TumCP↓, TumCMig↓, TumCI↓, eff↑, Imm↑, ROS↑, NF-kB↓, chemoP↑, JNK↑, FOXO↑, Myc↑, TumCCA↑, Apoptosis↑, RadioS↑, PD-L1↑, eff↑, CSCs↓, Dose↝, Half-Life↑,
5013- DSF,  Cu,  Z,    Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner in vitro, in mice and in a patient with metastatic disease
- vitro+vivo, Melanoma, NA - Case Report, Melanoma, NA
P-gp/ABCB1↓, NF-kB↓, ChemoSen↑, angioG↓, TumCG↓, TumMeta↓, Remission↑, toxicity↓, ATF2↓, CREB↓, cycA1/CCNA1↓, TumCG↓, angioG↓, Dose↝, toxicity↝,
4253- EA,    The effects of Ellagic acid supplementation on neurotrophic, inflammation, and oxidative stress factors, and indoleamine 2, 3-dioxygenase gene expression in multiple sclerosis patients with mild to moderate depressive symptoms: A randomized, triple-blind, placebo-controlled trial
- Human, MS, NA - NA, IBD, NA
*Mood↑, *BDNF↑, *5HT↑, *antiOx↑, *Inflam↓, *AntiCan↑, *QoL↑, *neuroP↑, *cognitive↑, *memory↑, *Dose↝,
6803- EA,    Effects of Ellagic Acid on Oxidative Stress Index, Inflammatory Markers and Quality of Life in Patients With Irritable Bowel Syndrome: Randomized Double-blind Clinical Trial
- Trial, IBD, NA
*Dose↝, *MDA↓, *TAC↑, *CRP↓, *IL6↓, *Inflam↓, *ROS↓, *QoL↑, *toxicity↓,
6802- EA,    Support ellagic acid therapy in patients with hormone refractory prostate cancer (HRPC) on standard chemotherapy using vinorelbine and estramustine phosphate
- Human, Pca, NA
*toxicity↓, chemoP↑, Neut↑, PSA↓, Dose↝,
6801- EA,    A radiotherapeutic paradox: ellagic acid sensitizes tumors while attenuating radiation-induced myocardial injury
- vitro+vivo, BC, 4T1
TumCCA↑, CDK4↓, RadioS↑, TumCG↓, *radioP↑, *cardioP↑, *antiOx↑, *ROS↓, Dose↑, selectivity↑, BioAv↓,
1605- EA,    Ellagic Acid and Cancer Hallmarks: Insights from Experimental Evidence
- Review, Var, NA
*BioAv↓, antiOx↓, Inflam↓, TumCP↓, TumCCA↑, cycD1/CCND1↓, cycE/CCNE↓, P53↑, P21↑, COX2/PTGS2↓, NF-kB↓, Akt↑, NOTCH↓, CDK2↓, CDK6↓, JAK↓, STAT3↓, EGFR↓, p‑ERK↓, p‑Akt↓, p‑STAT3↓, TGF-β↓, SMAD3↓, CDK6↓, Wnt/(β-catenin)↓, Myc↓, survivin↓, CDK8↓, PKCδ↓, tumCV↓, RadioS↑, eff↑, MDM2↓, XIAP↓, p‑RB1↓, PTEN↑, p‑FAK↓, Bax:Bcl2↑, Bcl-xL↓, Mcl-1↓, PUMA↑, NOXA↑, MMP↓, Cyt‑c↑, ROS↑, Ca+2↝, Endoglin↑, Diablo↑, AIF↑, iNOS↓, Casp9↑, Casp3↑, cl‑PARP↑, RadioS↑, Hif1a↓, HO-1↓, HO-2↓, SIRT1↓, selectivity↑, Dose∅, NHE1↓, Glycolysis↓, GlucoseCon↓, lactateProd↓, PDK1 / PDPK1?, PDK1 / PDPK1?, ECAR↝, COX1↓, Snail↓, Twist↓, cMyc↓, Telomerase↓, angioG↓, MMP2↓, MMP9↓, VEGF↓, Dose↝, PD-L1↓, eff↑, SIRT6↑, DNAdam↓,
1617- EA,  CUR,    The inhibition of human glutathione S-transferases activity by plant polyphenolic compounds ellagic acid and curcumin
- in-vitro, Nor, NA
Dose∅, GSTs↓,
1606- EA,    Ellagic acid inhibits proliferation and induced apoptosis via the Akt signaling pathway in HCT-15 colon adenocarcinoma cells
- in-vitro, Colon, HCT15
TumCP↓, cycD1/CCND1↓, Apoptosis↑, PI3K↓, Akt↓, ROS↑, Casp3↑, Cyt‑c↑, Bcl-2↓, TumCCA↑, Dose∅, ALP↓, LDH↓, PCNA↓, P53↑, Bax:Bcl2↑,
1608- EA,    Ellagic Acid from Hull Blackberries: Extraction, Purification, and Potential Anticancer Activity
- in-vitro, Cerv, HeLa - in-vitro, Liver, HepG2 - in-vitro, BC, MCF7 - in-vitro, Lung, A549 - in-vitro, Nor, HUVECs
eff↑, Dose∅, *BioAv↑, selectivity↑, TumCP↓, Casp↑, PTEN↑, TSC1↑, mTOR⇅, Akt↓, PDK1 / PDPK1↓, E6↓, E7↓, DNAdam↑, ROS↑, *BioAv↓, *BioEnh↑, *Half-Life∅,
6614- Ech,    Echinacea: a Miracle Herb against Aging and Cancer? Evidence In vivo in Mice
- in-vivo, Var, NA
*Imm↑, *AntiAge↑, OS↑, NK cell↑, PGE2↓, 5LO↓, COX2/PTGS2↓, Dose↝, eff↑,
6612- Ech,    Safety and Efficacy Profile of Echinacea purpurea to Prevent Common Cold Episodes: A Randomized, Double-Blind, Placebo-Controlled Trial
- Trial, Nor, NA
*Imm↑, Dose↝, eff↑,
6604- Ech,    Echinacea alkamide disposition and pharmacokinetics in humans after tablet ingestion
- Human, Nor, NA
*BioAv↑, *Half-Life↝, *Dose↝, Dose?,
6609- Ech,  Cic,    Echinacea purpurea Extract Enhances Natural Killer Cell Activity In Vivo by Upregulating MHC II and Th1-type CD4+ T Cell Responses
- in-vivo, Nor, NA
*Dose↝, *CD4+↑, *Th1 response↑, *NK cell↑, *Imm↑,
6610- Ech,  Cic,    A standardized extract of Echinacea purpurea containing higher chicoric acid content enhances immune function in murine macrophages and cyclophosphamide-induced immunosuppression mice
- in-vivo, Nor, NA
*NK cell↑, *Imm↑, Dose↝,
6618- Ech,    Kaempferols from Echinacea purpurea demonstrate anti-cancer potential by targeting anexelekto in breast cancer therapy using chemoinformatics approach
- Analysis, BC, NA
AXL↓, Dose?,
6617- Ech,    Echinacea Angustifolia DC Extract Induces Apoptosis and Cell Cycle Arrest and Synergizes with Paclitaxel in the MDA-MB-231 and MCF-7 Human Breast Cancer Cell Lines
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MCF7 - in-vitro, Nor, MCF10
Dose↝, selectivity↑, TumCCA↑, Apoptosis↑, toxicity↓, ChemoSen↑, other↝, *antiOx↑,
7191- EGb 761,    Pharmacokinetic drug interactions involving Ginkgo biloba
- NA, Nor, NA
*other∅, *Dose↝,
7194- EGb 761,    Kaempferol and quercetin, components of Ginkgo biloba extract (EGb 761), induce caspase-3-dependent apoptosis in oral cavity cancer cells
- in-vitro, Oral, NA
Casp3↑, Apoptosis↑, Dose↝, TumCP↓, cl‑PARP↑, AntiCan↑,
7203- EGb 761,    Ginkgo biloba extract EGb 761 is safe and effective in the treatment of mild dementia - a meta-analysis of patient subgroups in randomised controlled trials
- Review, AD, NA
cognitive↑, QoL↑, Dose↝,
7200- EGb 761,  PCA,    Optimized Ginkgo biloba extract EGb 761®: boosted therapeutic benefits with minimized CYP enzyme interference
*Dose↝, *AChE↓, *GSK‐3β↝, *eff↑, *cognitive↑, *toxicity↓,
7196- EGb 761,    Ginkgo biloba extract EGb 761 in patients with dementia and a history of cerebral infarction-meta-analysis of pooled data from randomised clinical trials
- Review, AD, NA - Review, Stroke, NA
*neuroP↑, *cognitive↑, *Stroke↓, *toxicity↓, Dose↝,
7225- EGb 761,    Efficacy and safety of Ginkgo biloba standardized extract in the treatment of vascular cognitive impairment: a randomized, double-blind, placebo-controlled clinical trial
- Trial, AD, NA
*cognitive↑, *Dose↝, *Dose↝,
7230- EGb 761,    Ginkgo biloba extract (EGb 761) promotes peripheral nerve regeneration and neovascularization after acellular nerve allografts in a rat model
- in-vivo, Nor, NA
*Dose↝, *NGF↑, *angioG↑, *VEGF↑, *SOX18↑, *CD133↑, *IL6↑,
7229- EGb 761,    Meta-analysis of the efficacy and safety of Ginkgo biloba extract for the treatment of dementia
- Review, AD, NA
*toxicity↓, *Dose↝, *ROS↓, *PAF↓, *memory↑, *BloodF↑, *antiOx↑, *Inflam↓, *Tinn↓,
7228- EGb 761,    Current Perspectives on the Beneficial Role of Ginkgo biloba in Neurological and Cerebrovascular Disorders
- Review, AD, NA
*Dose↝, *PAF↑, *AntiAg↑, *BloodF↑, *Inflam↓, *neuroP↑, *Stroke↓, *Dose↝, *Sepsis↓, *memory↑,
7222- EGb 761,    Ginkgo biloba extract EGb 761® in the symptomatic treatment of mild-to-moderate dementia: a profile of its use
- Review, AD, NA
*cognitive↑, *toxicity↓, *Dose↝, *BioAv↑, *Half-Life↑, *neuroP↑, *Half-Life↝, *Dose↝, *other↝, *eff↑,
7220- EGb 761,    Ginkgo Biloba Extract Inhibits Metastasis and ERK/Nuclear Factor kappa B (NF-κB) Signaling Pathway in Gastric Cancer
- vitro+vivo, GC, SGC-7901
TumCP↓, TumCMig↓, TumCI↓, p‑ERK↓, NF-kB↓, MMP2↓, eff↑, TumCG↓, TumMeta↓, Dose↝, TumVol↓,
7241- EGb 761,  ASA,    Effect of Ginkgo biloba (EGb 761) and aspirin on platelet aggregation and platelet function analysis among older adults at risk of cardiovascular disease: a randomized clinical trial
- Trial, Nor, NA
*Dose↝, *AntiAg∅,
7236- EGb 761,    Neuroprotective effects of bilobalide, a component of the Ginkgo biloba extract (EGb 761), in gerbil global brain ischemia
- in-vivo, Stroke, NA
*Dose↑, *Stroke↓,
3721- EGb 761,    Ginkgo biloba Extract in Alzheimer’s Disease: From Action Mechanisms to Medical Practice
- Review, AD, NA
*antiOx↑, *ROS↓, *SOD↑, *Catalase↑, *GSR↑, *MMP↑, *Inflam↓, *Aβ↓, *memory↑, *Dose↝, *BBB↑, *neuroP↑,
3245- EGCG,    (−)-Epigallocatechin-3-gallate protects PC12 cells against corticosterone-induced neurotoxicity via the hedgehog signaling pathway
- in-vitro, Nor, PC12
*neuroP↑, *Shh↑, *Gli1↑, *n-MYC↑, *Dose↝,
3201- EGCG,    Epigallocatechin Gallate (EGCG): Pharmacological Properties, Biological Activities and Therapeutic Potential
- Review, NA, NA
*AntiCan↑, *cardioP↑, *neuroP↑, *BioAv↝, *BioAv↓, *BioAv↓, *Dose↝, *Half-Life↝, *BioAv↑, *BBB↑, *hepatoP↓, *other↓, *Inflam↓, *NF-kB↓, *AP-1↓, *iNOS↓, *COX2/PTGS2↓, *ROS↓, *RNS↓, *IL8↓, *JAK↓, *PDGFR-BB↓, *IGF-1R↓, *MMP2↓, *P53↓, *NRF2↑, *TNF-α↓, *IL6↓, *E2Fs↑, *SOD1↑, *SOD2↑, Casp3↑, Cyt‑c↑, PARP↑, DNMTs↓, Telomerase↓, Hif1a↓, MMPs↓, BAX↑, Bak↑, Bcl-2↓, Bcl-xL↓, P53↑, PTEN↑, TumCP↓, MAPK↓, HGF/c-Met↓, TIMP1↑, HDAC↓, MMP9↓, uPA↓, GlutMet↓, ChemoSen↑, chemoP↑,
6781- EGCG,    Scientific opinion on the safety of green tea catechins
- Review, Nor, NA
*hepatoP↓, *Dose↝, *ALAT↑, *AST↑,
6780- EGCG,    The pharmacological activity of epigallocatechin-3-gallate (EGCG) on Alzheimer's disease animal model: A systematic review
- Review, AD, NA
*neuroP↑, *tau↓, *antiOx↑, *Inflam↓, *Apoptosis↓, *AChE↓, *TNF-α↓, *JNK↓, *NGF↑, *SOD↑, *GPx↑, *MDA↓, *NO↓, *ROS↓, *iNOS↓, *COX2/PTGS2↓, *BAX↓, *CHOP/DDIT3↓, *GRP78/BiP↓, *Bcl-2↑, *Dose↑, *BioAv↑, *hepatoP↓,
6779- EGCG,    Effectiveness of epigallocatechin gallate nanoparticles on the in-vivo treatment of Alzheimer's disease in a rat/mouse model: a systematic review
- Review, AD, NA
*BioAv↑, *ROS↓, *AChE↓, *Dose↝, *neuroP↑, *APP↓, *GSK‐3β↓, *PDK1 / PDPK1↓, *BBB↑, *memory↑,
6782- EGCG,    Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability
- Human, Nor, NA
*Dose↝, BioAv↝, Half-Life↝,
6789- EGCG,    Epigallocatechin-3-gallate (EGCG) for Clinical Trials: More Pitfalls than Promises?
- Review, Var, NA
BioAv↓, Half-Life↝, Half-Life↝, BioAv↝, *BioAv↑, *BioAv↓, *BioAv↑, *BioAv↑, *Dose↝, *toxicity↝,
4290- EGCG,    EGCG impedes human Tau aggregation and interacts with Tau
- in-vitro, AD, NA
*tau↓, *Dose↝, *neuroP↑, *antiOx↑,
2501- EGCG,    A Case of Complete and Durable Molecular Remission of Chronic Lymphocytic Leukemia Following Treatment with Epigallocatechin-3-gallate, an Extract of Green Tea
- Case Report, AML, NA
OS↑, Remission↑, eff↑, Dose↝,
6049- EGCG,  SeNPs,    Epigallocatechin-3-gallate (EGCG)-stabilized selenium nanoparticles coated with Tet-1 peptide to reduce amyloid-β aggregation and cytotoxicity
- Study, AD, PC12
*Aβ↓, *Dose↝, *BioAv↑, *ROS↓,
1975- EGCG,    Molecular bases of thioredoxin and thioredoxin reductase-mediated prooxidant actions of (-)-epigallocatechin-3-gallate
- in-vitro, Cerv, HeLa
TrxR↓, Trx↓, ROS↑, Dose↑,
1514- EGCG,    Preferential inhibition by (-)-epigallocatechin-3-gallate of the cell surface NADH oxidase and growth of transformed cells in culture
- in-vitro, Cerv, HeLa - in-vitro, Nor, MCF10
selectivity↑, *toxicity∅, TumCG↓, NADHdeh?, eff↑, ENOX2↓, Dose?,
1516- EGCG,    Epigallocatechin Gallate (EGCG): Pharmacological Properties, Biological Activities and Therapeutic Potential
- Review, NA, NA
*Dose∅, Half-Life∅, BioAv∅, BBB↑, toxicity∅, eff↓, Apoptosis↑, Casp3↑, Cyt‑c↑, cl‑PARP↑, DNMTs↓, Telomerase↓, angioG↓, Hif1a↓, NF-kB↓, MMPs↓, BAX↑, Bak↑, Bcl-2↓, Bcl-xL↓, P53↑, PTEN↑, IGF-1↓, H3↓, HDAC1↓, *LDH↓, *ROS↓,
6830- EMD,    Anticancer activity of emodin is associated with downregulation of CD155
- vitro+vivo, Melanoma, B16-BL6 - in-vitro, BC, E0771 - in-vitro, BC, 4T1
TumCP↓, TumCMig↓, TumCCA↑, CD155↓, Dose↓, other↝, TumCG↓,
5227- EMD,    Emodin and emodin-rich rhubarb inhibits histone deacetylase (HDAC) activity and cardiac myocyte hypertrophy
- vitro+vivo, Nor, NA
*cardioP↑, HDAC↓, HDAC1↓, HDAC2↓, ac‑H3↑, Dose↝, BioAv↓,
6110- EP,    Leukemic cell intracellular responses to nanosecond electric fields
- in-vitro, AML, NA
eff↑, EPR↑, other↝, other↝, Dose↝, Dose↝, Dose↝, eff↑,
5525- EP,    Cell responses without receptors and ligands, using nanosecond pulsed electric fields (nsPEFs)
- Review, Var, NA
CellMemb↑, Ca+2↑, ER Stress↑, ROS↑, MMP↓, VGCC↓, VGSC↓, Dose↝,
5527- EP,    Nanosecond pulsed electric field (nsPEF) application effects on human cells: intracellular membrane disruption and apoptosis induction
- in-vivo, Var, NA
*Dose↓, Apoptosis↑, DNAdam↑, mtDam↑,

Showing Research Papers: 351 to 400 of 1061
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1061

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

CD155↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   ENOX2↓, 1,   GSTs↓, 1,   HO-1↓, 1,   HO-2↓, 1,   NADHdeh?, 1,   ROS↑, 7,   SOD↓, 1,   Trx↓, 1,   TrxR↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 1,   MMP↓, 2,   mtDam↑, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

cMyc↓, 1,   CREB↓, 1,   ECAR↝, 1,   GlucoseCon↓, 1,   GlutMet↓, 1,   Glycolysis↓, 1,   lactateProd↓, 1,   LDH↓, 1,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 1,   SIRT1↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 2,   Akt↑, 1,   p‑Akt↓, 1,   Apoptosis↑, 6,   ATF2↓, 1,   Bak↑, 2,   BAX↑, 2,   Bax:Bcl2↑, 2,   Bcl-2↓, 3,   Bcl-xL↓, 3,   Casp↑, 1,   Casp3↑, 5,   Casp9↑, 1,   Cyt‑c↑, 4,   Diablo↑, 1,   HGF/c-Met↓, 1,   iNOS↓, 1,   JNK↑, 1,   MAPK↓, 2,   Mcl-1↓, 1,   MDM2↓, 1,   Myc↓, 1,   Myc↑, 1,   NOXA↑, 1,   PUMA↑, 1,   survivin↓, 1,   Telomerase↓, 3,  

Transcription & Epigenetics(tgid=7) ⓘ

H3↓, 1,   ac‑H3↑, 1,   other↝, 4,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,   DNAdam↑, 3,   DNMTs↓, 2,   P53↑, 4,   PARP↑, 1,   cl‑PARP↑, 3,   PCNA↓, 1,   SIRT6↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 1,   cycA1/CCNA1↓, 1,   cycD1/CCND1↓, 2,   cycE/CCNE↓, 1,   P21↑, 1,   p‑RB1↓, 1,   TumCCA↑, 6,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 1,   CDK8↓, 1,   CSCs↓, 2,   EMT↓, 1,   p‑ERK↓, 2,   FOXO↑, 1,   HDAC↓, 2,   HDAC1↓, 2,   HDAC2↓, 1,   IGF-1↓, 1,   mTOR⇅, 1,   NOTCH↓, 1,   PI3K↓, 1,   PTEN↑, 4,   STAT3↓, 1,   p‑STAT3↓, 1,   TumCG↓, 6,   VGCC↓, 1,   VGSC↓, 1,   Wnt/(β-catenin)↓, 1,  

Migration(tgid=13) ⓘ

5LO↓, 1,   AXL↓, 1,   Ca+2↑, 1,   Ca+2↝, 1,   p‑FAK↓, 1,   MMP2↓, 2,   MMP9↓, 2,   MMPs↓, 2,   PKCδ↓, 1,   SMAD3↓, 1,   Snail↓, 1,   TGF-β↓, 1,   TIMP1↑, 1,   TSC1↑, 1,   TumCI↓, 2,   TumCMig↓, 3,   TumCP↓, 8,   TumMeta↓, 3,   Twist↓, 1,   uPA↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 5,   EGFR↓, 1,   Endoglin↑, 1,   EPR↑, 1,   Hif1a↓, 3,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   CellMemb↑, 1,   NHE1↓, 1,   P-gp/ABCB1↓, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 1,   COX2/PTGS2↓, 2,   Imm↑, 2,   Inflam↓, 1,   JAK↓, 1,   Neut↑, 1,   NF-kB↓, 6,   NK cell↑, 1,   PD-L1↓, 1,   PD-L1↑, 1,   PGE2↓, 1,   PSA↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CDK6↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 3,   BioAv↑, 1,   BioAv↝, 3,   BioAv∅, 1,   ChemoSen↑, 4,   Dose?, 3,   Dose↓, 1,   Dose↑, 2,   Dose↝, 19,   Dose∅, 4,   eff↓, 1,   eff↑, 14,   Half-Life↑, 1,   Half-Life↝, 3,   Half-Life∅, 1,   RadioS↑, 5,   selectivity↑, 5,  

Clinical Biomarkers(tgid=22) ⓘ

ALP↓, 1,   E6↓, 1,   E7↓, 1,   EGFR↓, 1,   LDH↓, 1,   Myc↓, 1,   Myc↑, 1,   PD-L1↓, 1,   PD-L1↑, 1,   PSA↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiTum↑, 1,   chemoP↑, 3,   cognitive↑, 1,   OS↑, 2,   QoL↑, 1,   Remission↑, 2,   toxicity↓, 2,   toxicity↝, 2,   toxicity∅, 1,   TumVol↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

Sepsis↓, 1,  
Total Targets: 176

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

PAF↓, 1,   PAF↑, 1,   Stroke↓, 3,   Tinn↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 7,   Catalase↑, 1,   GPx↑, 1,   GSR↑, 1,   MDA↓, 2,   NRF2↑, 1,   RNS↓, 1,   ROS↓, 9,   SOD↑, 2,   SOD1↑, 1,   SOD2↑, 1,   TAC↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↑, 1,   LDH↓, 1,   PDK1 / PDPK1↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,   BAX↓, 1,   Bcl-2↑, 1,   iNOS↓, 2,   JNK↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↓, 1,   other↝, 1,   other∅, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   GRP78/BiP↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

P53↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

E2Fs↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD133↑, 1,   Gli1↑, 1,   GSK‐3β↓, 1,   GSK‐3β↝, 1,   IGF-1R↓, 1,   n-MYC↑, 1,   Shh↑, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   AntiAg∅, 1,   AP-1↓, 1,   APP↓, 1,   MMP2↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   NO↓, 1,   PDGFR-BB↓, 1,   SOX18↑, 1,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 3,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   COX2/PTGS2↓, 2,   CRP↓, 1,   IL6↓, 2,   IL6↑, 1,   IL8↓, 1,   Imm↑, 4,   Inflam↓, 8,   JAK↓, 1,   NF-kB↓, 1,   NK cell↑, 2,   Th1 response↑, 1,   TNF-α↓, 2,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   AChE↓, 3,   BDNF↑, 1,   NGF↑, 2,   tau↓, 2,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 5,   BioAv↑, 10,   BioAv↝, 1,   BioEnh↑, 1,   Dose↓, 1,   Dose↑, 2,   Dose↝, 24,   Dose∅, 1,   eff↑, 2,   Half-Life↑, 1,   Half-Life↝, 3,   Half-Life∅, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↑, 1,   AST↑, 1,   BloodF↑, 2,   CRP↓, 1,   IL6↓, 2,   IL6↑, 1,   LDH↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↑, 2,   cardioP↑, 3,   cognitive↑, 5,   hepatoP↓, 3,   memory↑, 5,   Mood↑, 1,   neuroP↑, 10,   QoL↑, 2,   radioP↑, 1,   toxicity↓, 6,   toxicity↝, 1,   toxicity∅, 1,  

Infection & Microbiome(tgid=24) ⓘ

Sepsis↓, 1,  
Total Targets: 102

Scientific Paper Hit Count for: Dose, Dosage
39 Magnetic Fields
31 Selenium NanoParticles
27 Hydrogen Gas
24 Radiotherapy/Radiation
22 Curcumin
19 Silver-NanoParticles
19 Resveratrol
19 Chemotherapy
17 Vitamin C (Ascorbic Acid)
16 EGCG (Epigallocatechin Gallate)
16 Selenium
16 Selenite (Sodium)
15 Ginkgo biloba-EGb 761
14 Apigenin (mainly Parsley)
14 Propolis -bee glue
14 Chlorogenic acid
12 Carvacrol
12 Ginger/6-Shogaol/Gingerol
12 Inositol
12 Kaempferol
11 buckwheat sprouts
11 Choline
11 Ellagic acid
11 Sulforaphane (mainly Broccoli)
11 Folic Acid, Vit B9
11 Hyperthermia
10 isoquercitrin
10 Lycopene
10 Hydroxycinnamic-acid
10 Lemongrass Extract/Citral
10 Lactoferrin/Talactoferrin
9 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
9 Baicalein
9 Dichloroacetate
9 Exercise
9 itraconazole
9 Magnetic Field Rotating
8 Rutin
8 Auranofin
8 Melatonin
8 Citric Acid
8 Dandelion Root
8 Ferulic acid
8 Fenbendazole
8 Fisetin
8 Fucoidan
8 Ginkgo biloba
8 Ginkgetin
8 HydroxyTyrosol
8 Silymarin (Milk Thistle) silibinin
7 3-bromopyruvate
7 α-Bisabolol / Chamomile oil
7 Quercetin
7 Mung Bean Sprouts
7 Capsaicin
7 Centella asiatica / Gotu kola → asiaticoside
7 chitosan
7 Echinacea
7 Electrical Pulses
7 Formononetin
7 Gamma-aminobutyric acid
7 Genistein (soy isoflavone)
7 Hibiscus sabdariffa
7 Indole-3-carbinol
7 Thymoquinone
7 Whole Body Vibration
6 5-Hydroxytryptophan
6 Metformin
6 Aspirin
6 Astaxanthin
6 Vitexin
6 Caffeic acid
6 immunotherapy
6 nicotinamide adenine dinucleotide
6 Copper and Cu NanoParticles
6 Eugenol
6 Ivermectin
6 Vitamin D3
6 Honokiol
6 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
6 iodine
6 Inulin Prebiotic
6 SonoDynamic Therapy UltraSound
6 Phenethyl isothiocyanate
5 Alpha-Lipoic-Acid
5 Cynara scolymus/Globe Artichoke/Artichoke Extract
5 Allicin (mainly Garlic)
5 Acetyl-l-carnitine
5 Paclitaxel/Taxol
5 Boron
5 isoorientin
5 Isovitexin
5 Chocolate
5 Spermidine
5 Oxygen, Hyperbaric
5 diet FMD Fasting Mimicking Diet
5 Vitamin B12
5 Gossypol/AT-101
5 Grapeseed extract
5 Isoliquiritigenin
5 Licorice
5 isoflavones
5 Licochalcone A
5 Bicarbonate(Sodium)
5 Phenylbutyrate
5 EMF
5 Rosmarinic acid
5 VitK3,menadione
4 cetuximab
4 Cisplatin
4 Ashwagandha(Withaferin A)
4 Berberine
4 Boswellia (frankincense)
4 Butyrate
4 Celastrol
4 Chrysin
4 Chyawanprash
4 Cichoric acid / Chicoric acid
4 Coenzyme Q10
4 HydroxyCitric Acid
4 Garcinol
4 Diclofenac
4 Docosahexaenoic Acid
4 eicosapentaenoic acid
4 Shilajit/Fulvic Acid
4 Gallic acid
4 capecitabine
4 probiotics
4 Propyl gallate
3 Astragalus
3 Fennel Oil/Foeniculum vulgare
3 Angelica archangelica / Garden Angelica
3 Artemisinin
3 Aloe anthraquinones
3 beta-glucans
3 Beta-Caryophyllene
3 Bromelain
3 borneol
3 Cat’s Claw
3 chaetocin
3 doxorubicin
3 Calorie Restriction Mimetics
3 Crocetin
3 Dasatinib/Phyrago
3 Disulfiram
3 Eurycomanone
3 Silicic Acid
3 Gambogic Acid
3 Huperzine A/Huperzia serrata
3 Isobavachalcone
3 Lapatinib
3 metronomic chemo
3 Methylsulfonylmethane
3 Oleuropein
3 Piperlongumine
3 Shikonin
3 Aflavin-3,3′-digallate
3 Turmerones
3 Urolithin
3 Vitamin B1/Thiamine
3 Vitamin E
3 Vitamin K2
2 1,8-Cineole
2 Photodynamic Therapy
2 Glucose
2 almonertinib
2 Bevacizumab (brand Avastin)
2 DTS(dibenzyl trisulphide) from Anamu
2 Anti-oxidants
2 Ascorbyl Palmitate
2 Atorvastatin
2 Betulinic acid
2 beta-carotene(VitA)
2 Bicalutamide
2 Bortezomib
2 Lecithin
2 Calcium
2 Sorafenib (brand name Nexavar)
2 Celecoxib
2 Cynaropicrin
2 diet Plant based
2 diet Short Term Fasting
2 D-limonene
2 Emodin
2 5-fluorouracil
2 Evodiamine
2 Vitamin B6,pyridoxine
2 Flickering Light Stimulation
2 Germanium Organic/Ge-132 / propagermanium (organogermanium)
2 Germanium inorganic
2 Geraniol
2 Ginkgolide B
2 Gold NanoParticles
2 Germacranolide sesquiterpene lactone
2 Helleborus niger extracts – Christmas Rose
2 Recombinant Methioninase
2 Juglone
2 Potassium
2 L-ornithine
2 Lactobacillus
2 Luteolin
2 nivolumab
2 Iron
2 Niclosamide (Niclocide)
2 Bifidobacterium
2 Phosphatidylserine
2 Rauwolfia serpentina/Indian Snakeroot
2 Vitamin B5,Pantothenic Acid
1 5-Aminolevulinic acid
1 Annona atemoya Leaf Extract
1 Anethole/trans-Anethole
1 Acer okamotoanum
1 Aromatherapy
1 Baicalin
1 Biochanin A
1 bempedoic acid
1 Bufalin/Huachansu
1 Brucea javanica
1 Bacopa monnieri
1 brusatol
1 Bruteridin(bergamot juice)
1 Black Seed Oil/Nigella sativa
1 urea
1 Catechins
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Cannabidiol
1 Chlorophyllin
1 Cinnamon
1 Carica papaya leaf extract
1 Camptothecin
1 CUSP9
1 Cysteamine
1 diet Ketogenic
1 Dipyridamole
1 Docetaxel
1 Zinc
1 Protocatechuic acid
1 Estragole
1 Aluminum
1 ferumoxytol
1 Auditory Gamma Stimulation / 40 Hz Auditory Stimulation
1 Arsenic trioxide
1 Vitamin A, Retinoic Acid
1 Bifidobacterium animalis subsp. lactis GCL2505
1 Glabrescione B
1 carboplatin
1 Graviola
1 hydrogen sulfide
1 High-Ozonide Oil
1 Hormone replacement therapy
1 Hyperoside
1 Extracorporeal Shock Wave Therapy
1 Anthocyanins
1 Gemcitabine (Gemzar)
1 lambertianic acid
1 Lapachol
1 Lasiodin
1 MCToil
1 Sulodexide
1 magnetic nanoparticles
1 Mistletoe/Viscum album Extracts
1 Mushroom Lion’s Mane
1 Naringin
1 Nimbolide
1 ipilimumab
1 Aidi injection
1 Phenolic Acids
1 Polyphenols
1 alpha Linolenic acid
1 Pterostilbene
1 Ramucirumab (CYRAMZA)
1 Radio Frequency
1 Sinapic acid
1 salinomycin
1 α-Santalol/Sandalwood oil
1 Sulfasalazine
1 irinotecan
1 Terpinen-4-ol / Tea Tree Oil
1 Taurine
1 Triphala
1 triptolide
1 Thymol-Thymus vulgaris
1 Ursolic acid
1 Vanillic Acid
1 Transarterial Chemoembolization
1 Xylitol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1114  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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