TumCP Cancer Research Results

TumCP, Tumor Cell proliferation: Click to Expand ⟱
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Tumor cell proliferation is a key characteristic of cancer. It refers to the rapid and uncontrolled growth of cells that can lead to the formation of tumors.
Scientific Papers found: Click to Expand⟱
482- CUR,  PDT,    The Antitumor Effect of Curcumin in Urothelial Cancer Cells Is Enhanced by Light Exposure In Vitro
- in-vitro, Bladder, RT112 - in-vitro, Bladder, UMUC3
Apoptosis↑, TumCG↓, TumCP↓,
480- CUR,    Curcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells
- in-vitro, GBM, SNB19
TumCP↓, TumCMig↓, Apoptosis↑, TumCCA↑, NEDD9↓, NOTCH1↓, p‑Akt↓,
457- CUR,    Curcumin regulates proliferation, autophagy, and apoptosis in gastric cancer cells by affecting PI3K and P53 signaling
- in-vitro, GC, SGC-7901 - in-vitro, GC, BGC-823
TumCP↓, Apoptosis↑, TumAuto↑, P53↑, PI3K↓, P21↑, p‑Akt↓, p‑mTOR↓, Bcl-2↓, Bcl-xL↓, LC3I↓, BAX↑, Beclin-1/ATG6↑, cl‑Casp3↑, cl‑PARP↑, LC3II↑, ATG3↑, ATG5↑,
438- CUR,    Curcumin Reduces Colorectal Cancer Cell Proliferation and Migration and Slows In Vivo Growth of Liver Metastases in Rats
- vitro+vivo, CRC, CC531
TumCP↓, TumVol↓, Albumin↑, ALP↑, AST↑, ALAT↑, ChE↓,
456- CUR,    Curcumin Promoted miR-34a Expression and Suppressed Proliferation of Gastric Cancer Cells
- vitro+vivo, GC, SGC-7901
miR-34a↑, TumCP↓, TumCMig↓, TumCI↓, TumCCA↑, Bcl-2↓, CDK4/6↓, cycD1/CCND1↓,
454- CUR,    Curcumin-Induced DNA Demethylation in Human Gastric Cancer Cells Is Mediated by the DNA-Damage Response Pathway
- in-vitro, GC, MGC803
TumCMig↓, TumCP↓, ROS↑, mtDam↑, DNAdam↑, Apoptosis↑, ATR↑, P21↑, p‑P53↑, GADD45A↑, p‑γH2AX↑,
450- CUR,    Curcumin may be a potential adjuvant treatment drug for colon cancer by targeting CD44
- in-vitro, CRC, HCT116 - in-vitro, CRC, HCT8
TumCP↓, TumCMig↓, CD44↓, CSCs↓,
449- CUR,    Curcumin Suppresses the Colon Cancer Proliferation by Inhibiting Wnt/β-Catenin Pathways via miR-130a
- vitro+vivo, CRC, SW480
TumCP↓, β-catenin/ZEB1↓, TCF↓, miR-21↓, NKD2↑, miR-130a↓,
446- CUR,    The Influence of Curcumin on the Downregulation of MYC, Insulin and IGF-1 Receptors: A Possible Mechanism Underlying the Anti-Growth and Anti-Migration in Chemoresistant Colorectal Cancer Cells
- in-vitro, CRC, SW480
IR↓, IGF-1↓, Myc↓, TumCMig↓, TumCP↓,
442- CUR,  5-FU,    Curcumin may reverse 5-fluorouracil resistance on colonic cancer cells by regulating TET1-NKD-Wnt signal pathway to inhibit the EMT progress
- in-vitro, CRC, HCT116
Apoptosis↑, TumCP↓, TumCCA↑, TET1↑, NKD2↑, Wnt↓, EMT↓, Vim↑, E-cadherin↓, β-catenin/ZEB1↓, TCF↓, AXIN1↓,
440- CUR,    Curcumin Reverses NNMT-Induced 5-Fluorouracil Resistance via Increasing ROS and Cell Cycle Arrest in Colorectal Cancer Cells
- vitro+vivo, CRC, SW480 - vitro+vivo, CRC, HT-29
NNMT↓, p‑STAT3↓, TumCP↓, TumCCA↑, ROS↑,
137- CUR,    Curcumin induces G0/G1 arrest and apoptosis in hormone independent prostate cancer DU-145 cells by down regulating Notch signaling
- in-vitro, Pca, DU145
NOTCH1↓, cycD1/CCND1↓, CDK2↓, P21↑, p27/CDKN1B↑, P53↑, Bcl-2↓, Casp3↑, Casp9↑, TumCCA↑, TumCP↓, Apoptosis↑,
146- CUR,  EGCG,    Synergistic effect of curcumin on epigallocatechin gallate-induced anticancer action in PC3 prostate cancer cells
- in-vitro, Pca, PC3 - in-vitro, Pca, LNCaP - in-vitro, Pca, DU145
P21↑, TumCCA↑, TumCP↓, BioAv↓,
152- CUR,    Anti-cancer activity of curcumin loaded nanoparticles in prostate cancer
- in-vivo, Pca, NA
β-catenin/ZEB1↓, AR↓, STAT3↓, p‑Akt↓, Mcl-1↓, Bcl-xL↓, cl‑PARP↑, miR-21↓, miR-205↑, TumCG↓, TumCP↓, TumCI↓, angioG↓, TumMeta↓,
133- CUR,    Curcumin inhibits prostate cancer by targeting PGK1 in the FOXD3/miR-143 axis
- in-vitro, Pca, DU145 - in-vitro, Pca, PC3
miR-143↑, PDK1 / PDPK1↓, FOXD3↑, TumCP↓, TumCMig↓, *Inflam↓, *antiOx↑, *chemoPv↑, RadioS↑, ChemoSen↑,
14- CUR,    Curcumin, a Dietary Component, Has Anticancer, Chemosensitization, and Radiosensitization Effects by Down-regulating the MDM2 Oncogene through the PI3K/mTOR/ETS2 Pathway
- vitro+vivo, Pca, PC3
PI3K/mTOR/ETS2↓, MDM2↓, P21↑, Apoptosis↑, TumCP↓, eff↑, RadioS↑,
11- CUR,    Curcumin inhibits hypoxia-induced epithelial‑mesenchymal transition in pancreatic cancer cells via suppression of the hedgehog signaling pathway
- in-vitro, PC, PANC1
HH↓, Shh↓, Smo↓, Gli1↓, N-cadherin↓, E-cadherin↑, Vim↓, TumCP↓, TumCMig↓, TumCI↓, EMT↓, chemoPv↑,
9- CUR,    Curcumin Suppresses Malignant Glioma Cells Growth and Induces Apoptosis by Inhibition of SHH/GLI1 Signaling Pathway in Vitro and Vivo
- vitro+vivo, MG, U87MG - vitro+vivo, MG, T98G
HH↓, Shh↓, Gli1↓, cycD1/CCND1↓, Bcl-2↓, FOXM1↓, Bax:Bcl2↑, TumCP↓, TumCMig↓, Apoptosis↑, TumVol↑, TumCCA↑, Casp3↑, OS↑,
165- CUR,    Curcumin interrupts the interaction between the androgen receptor and Wnt/β-catenin signaling pathway in LNCaP prostate cancer cells
- in-vitro, Pca, LNCaP
AR↓, β-catenin/ZEB1↓, p‑Akt↓, GSK‐3β↓, p‑β-catenin/ZEB1↑, cycD1/CCND1↓, cMyc↓, chemoPv↑, TumCP↓,
181- CUR,    The effects of curcumin on the invasiveness of prostate cancer in vitro and in vivo
- vitro+vivo, Pca, DU145
MMP2↓, MMP9↓, TumCP↓, TumCI↓,
168- CUR,    Curcumin inhibits Akt/mammalian target of rapamycin signaling through protein phosphatase-dependent mechanism
- in-vitro, Pca, PC3
Akt↓, mTOR↓, AMPK↑, TAp63α↑, TumCP↓,
4826- CUR,    The Bright Side of Curcumin: A Narrative Review of Its Therapeutic Potential in Cancer Management
- Review, Var, NA
*antiOx↑, *Inflam↑, *ROS↓, Apoptosis↑, TumCP↓, BioAv↓, Half-Life↓, eff↑, TumCCA↑, BAX↑, Bak↑, PUMA↑, BIM↑, NOXA↑, TRAIL↑, Bcl-2↓, Bcl-xL↓, survivin↓, XIAP↓, cMyc↓, Casp↑, NF-kB↓, STAT3↓, AP-1↓, angioG↓, TumMeta↑, VEGF↓, MMPs↓, DNMTs↓, HDAC↓, ROS↑,
4652- CUR,    Anticancer effect of curcumin on breast cancer and stem cells
- Review, BC, NA
TumCP↓, TumMeta↓, TumCCA↑, Apoptosis↑, CSCs↓, NF-kB↓, Telomerase↓, Cyt‑c↑, Casp9↑, Casp3↑, E-cadherin↑,
4709- CUR,    Curcumin Regulates Cancer Progression: Focus on ncRNAs and Molecular Signaling Pathways
- Review, Var, NA
miR-21↓, TumCP↓, TumCMig↓, TumCI↓, Apoptosis↑, miR-99↑, JAK↓, STAT↓, cycD1/CCND1↓, P21↑, ChemoSen↑, miR-192-5p↑, cMyc↓, Wnt↓, β-catenin/ZEB1↓, miR-130a↓,
4676- CUR,    Curcumin suppresses stem-like traits of lung cancer cells via inhibiting the JAK2/STAT3 signaling pathway
- vitro+vivo, Lung, H460
CSCs↓, JAK2↓, STAT3↓, TumCP↓, TumCG↓,
2974- CUR,    Curcumin Suppresses Metastasis via Sp-1, FAK Inhibition, and E-Cadherin Upregulation in Colorectal Cancer
- in-vitro, CRC, HCT116 - in-vitro, CRC, HT29 - in-vitro, CRC, HCT15 - in-vitro, CRC, COLO205 - in-vitro, CRC, SW-620 - in-vivo, NA, NA
TumCMig↓, TumCI↓, TumCG↓, TumMeta↓, Sp1/3/4↓, HDAC4↓, FAK↓, CD24↓, E-cadherin↑, EMT↓, TumCP↓, NF-kB↓, AP-1↝, STAT3↓, P53?, β-catenin/ZEB1↓, NOTCH1↝, Hif1a↝, PPARα↝, Rho↓, MMP2↓, MMP9↓,
6234- CUSP9,    In Vitro and Clinical Compassionate Use Experiences with the Drug-Repurposing Approach CUSP9v3 in Glioblastoma
- Human, GBM, NA
TumCP↓, Apoptosis↑, TumCMig↓, tumCV↓, TumCG↓, cl‑Casp3↑,
6249- Cyc,    Cyclopamine tartrate, an inhibitor of Hedgehog signaling, strongly interferes with mitochondrial function and suppresses aerobic respiration in lung cancer cells
- in-vitro, NSCLC, A549 - in-vitro, NSCLC, H1299
HH↓, OCR↓, TumCP↓, Apoptosis↑, ROS↑, MMP↑, mtDam↑,
6246- Cyc,    Cyclopamine is a novel Hedgehog signaling inhibitor with significant anti-proliferative, anti-invasive and anti-estrogenic potency in human breast cancer cells
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231
HH↓, TumCP↓, TumCCA↓, TumCI↓, NF-kB↓, MMP2↓, MMP9↓, ERα/ESR1↓, cycD1/CCND1↓,
6247- Cyc,    Sonic Hedgehog Pathway Contributes to Gastric Cancer Cell Growth and Proliferation
- vitro+vivo, GC, MKN45
Shh↓, TumCP↓, TumCCA↓, Apoptosis↓, TumCG↓, cycD1/CCND1↓,
7443- CYN,    Cynaropicrin, a sesquiterpene lactone, triggers apoptotic cell death in triple negative breast cancer cells
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MCF7
TumCP↓, Apoptosis↑, BAX↑, Casp3↑, Casp8↑, Casp9↑, Bcl-2↓,
7451- CYN,    Inhibitory effects of cynaropicrin on human melanoma progression by targeting MAPK, NF‐κB, and Nrf‐2 signaling pathways in vitro
- in-vitro, Melanoma, A375
TumCP↓, Casp3↑, Apoptosis↑, TumCMig↓, TumCI↓, ERK↓, NF-kB↓, ROS↓, HO-1↑, NRF2↑, Bcl-2↓, NF-kB↓, other↝,
7449- CYN,    Cytotoxic and pro-apoptotic activities of cynaropicrin, a sesquiterpene lactone, on the viability of leukocyte cancer cell lines
- in-vitro, lymphoma, U937 - in-vitro, AML, Jurkat
TumCP↓, selectivity↑, Apoptosis↑, TumCCA↑, DNAdam↑, eff↓, ROS↑, tumCV↓,
1871- DAP,    Targeting PDK1 with dichloroacetophenone to inhibit acute myeloid leukemia (AML) cell growth
- in-vitro, AML, U937 - in-vivo, AML, NA
TumCP↓, Apoptosis↑, TumCG↓, PDK1 / PDPK1↓, cl‑PARP↑, Bcl-xL↓, Bcl-2↓, Beclin-1/ATG6↓, ATG3↓, PI3K↓, Akt↓, eff↑,
6686- DAP,    Lactoferrin-encapsulated dichloroacetophenone (DAP) nanoparticles enhance drug delivery and anti-tumor efficacy in prostate cancer
- in-vivo, Pca, NA
PDK1 / PDPK1↓, TumCP↓, TumCMig↓, BioAv↓, BioAv↑, Apoptosis↑, Casp3↑, Casp7↑, Glycolysis↓,
6593- DAS,    Dasatinib: a potent SRC inhibitor in clinical development for the treatment of solid tumors
TumCP↓, TumCI↓, TumMeta↓, eff↑, Src↓,
6683- DCA,    Dichloroacetate for Cancer Treatment: Some Facts and Many Doubts
- Review, Var, NA
PDK1 / PDPK1↓, lactateProd↓, Apoptosis↑, TumCP↓, selectivity↑, other↝, Dose↝, BioAv↑, Half-Life↓, Glycolysis↓, OXPHOS↑, Casp↑, i-pH↓, COX2/PTGS2↑, Hif1a↓, angioG↓, HMG-CoA↓, GSTZ1↓, OCR↑, lipoGen↓, fatigue↓, survivin↓, miR-375↑, eff↓, CSCs↓, TumAuto↑, mTOR↓, TumCI↓, TumVol↓, TumW↓, ATP↓, Warburg↓, eff↑, e-pH↑, eff↑, eff↑, other↝, RadioS↑, toxicity↓, Dose↝, eff↑, eff↑, eff↑, toxicity↝, eff↓,
1865- DCA,    Reversal of the glycolytic phenotype by dichloroacetate inhibits metastatic breast cancer cell growth in vitro and in vivo
- in-vivo, BC, NA - in-vitro, BC, MCF7 - in-vitro, BC, T47D
TumCG↓, TumCP↓, AntiCan↑,
1889- DCA,    A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
- Review, Var, NA
PDKs↓, Glycolysis↓, mt-H2O2↑, Apoptosis↑, TumCP↓, TumCG↓, toxicity∅,
1445- Deg,    Deguelin--an inhibitor to tumor lymphangiogenesis and lymphatic metastasis by downregulation of vascular endothelial cell growth factor-D in lung tumor model
- in-vivo, lymphoma, NA - in-vitro, lymphoma, NA
Akt↓, TumCP↓, TumCMig↓, VEGF↓, TumCG↓, OS↑,
6676- Deg,    Deguelin’s Anticancer Bioactivity: Challenges and Opportunities in Medicinal Chemistry
- Review, Var, NA
TumCP↓, Apoptosis↑, NF-kB↓, Wnt↓, TumCCA↑, TumMeta↑, antiOx↑, Inflam↓, angioG↓, Half-Life↑, MMP2↓, MMP9↓, Casp9↑, Casp3↑, EMT↓, PTEN↑, ChemoSen↑, toxicity↑, *BBB↑,
6673- Deg,    Deguelin, an Akt inhibitor, suppresses IkappaBalpha kinase activation leading to suppression of NF-kappaB-regulated gene expression, potentiation of apoptosis, and inhibition of cellular invasion
NF-kB↓, IKKα↓, TNFR 1↓, TumCP↓, TumCI↓,
6671- Deg,    A Novel Derivative of the Natural Agent Deguelin for Cancer Chemoprevention and Therapy
- in-vitro, Nor, BEAS-2B - in-vitro, Lung, H1299 - in-vitro, Lung, H460
HSP90↓, toxicity↝, eff↑, chemoPv↑, p53 Wildtype↓, CDK4↓, MAPK↓, Hif1a↓, selectivity↑, compI↓, TumCP↓, BioAv↑,
6677- Deg,    Deguelin inhibits non-small cell lung cancer via down-regulating Hexokinases II-mediated glycolysis
- in-vitro, NSCLC, NA
Glycolysis↓, TumCG↓, Akt↓, Apoptosis↑, TumCP↓, HK2↓, PI3K↓, cMyc↓,
6706- DFC,  MET,    Frontiers | Combined Metabolic Targeting With Metformin and the NSAIDs Diflunisal and Diclofenac Induces Apoptosis in Acute Myeloid Leukemia Cells
- in-vitro, AML, U937
lactateProd↓, TumCP↓, eff↑, Glycolysis↓,
6707- DFC,    Markers of mitochondrial dysfunction during the diclofenac-induced apoptosis in melanoma cell lines
- in-vitro, Melanoma, NA
TumCP↓, ROS↑, Bax:Bcl2↑, Casp3↑, SOD2↑, Cyt‑c↑,
6688- DFC,    New Aspects of an Old Drug – Diclofenac Targets MYC and Glucose Metabolism in Tumor Cells
- in-vivo, lymphoma, U937
AntiCan↑, COX2/PTGS2↓, Myc↓, GLUT1↓, LDHA↓, MCT1↓, GlucoseCon↓, lactateProd↓, TumCP↓, other∅, toxicity↝,
6696- DFC,  MET,    Combined Modulation of Tumor Metabolism by Metformin and Diclofenac in Glioma
- in-vitro, GBM, GBM
compI↓, Glycolysis↓, OCR↓, Glycolysis↑, lactateProd↓, eff↑, TumCP↓, TumCMig↓, TumCD∅,
6695- DFC,    Inhibition of lactate dehydrogenase A by diclofenac sodium induces apoptosis in HeLa cells through activation of AMPK
- in-vitro, Cerv, HeLa
other↝, Glycolysis↓, LDHA↓, Hypoxia↓, Apoptosis↑, lactateProd↓, ATP↓, mt-ROS↑, DNAdam↑, lipid-P↑, AMPK↑, p‑S6K↓, TumCP↓, Dose↝, selectivity↑, i-MDA↑, mtDam↑,
6691- DFC,    Diclofenac impairs the proliferation and glucose metabolism of triple-negative breast cancer cells by targeting the c-Myc pathway
- in-vitro, Melanoma, NA - in-vitro, BC, MDA-MB-231 - in-vitro, BC, HCC1937 - in-vitro, BC, MCF7
Glycolysis↓, Apoptosis↑, cMyc↓, GLUT1↓, TumCP↓, HK2↓, TumCP↓,

Showing Research Papers: 351 to 400 of 1103
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1103

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

miR-375↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   compI↓, 2,   GSTZ1↓, 1,   mt-H2O2↑, 1,   HO-1↑, 1,   lipid-P↑, 1,   i-MDA↑, 1,   NRF2↑, 1,   OXPHOS↑, 1,   ROS↓, 1,   ROS↑, 6,   mt-ROS↑, 1,   SOD2↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 2,   MMP↑, 1,   mtDam↑, 3,   OCR↓, 2,   OCR↑, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↑, 1,   AMPK↑, 2,   cMyc↓, 5,   GlucoseCon↓, 1,   Glycolysis↓, 8,   Glycolysis↑, 1,   HK2↓, 2,   HMG-CoA↓, 1,   IR↓, 1,   lactateProd↓, 5,   LDHA↓, 2,   lipoGen↓, 1,   NNMT↓, 1,   PDK1 / PDPK1↓, 4,   PDKs↓, 1,   PI3K/mTOR/ETS2↓, 1,   PPARα↝, 1,   p‑S6K↓, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 4,   p‑Akt↓, 4,   Apoptosis↓, 1,   Apoptosis↑, 24,   Bak↑, 1,   BAX↑, 3,   Bax:Bcl2↑, 2,   Bcl-2↓, 8,   Bcl-xL↓, 4,   BIM↑, 1,   Casp↑, 2,   Casp3↑, 8,   cl‑Casp3↑, 2,   Casp7↑, 1,   Casp8↑, 1,   Casp9↑, 4,   Cyt‑c↑, 2,   MAPK↓, 1,   Mcl-1↓, 1,   MCT1↓, 1,   MDM2↓, 1,   Myc↓, 2,   NOXA↑, 1,   p27/CDKN1B↑, 1,   PUMA↑, 1,   survivin↓, 2,   Telomerase↓, 1,   TNFR 1↓, 1,   TRAIL↑, 1,   TumCD∅, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

FOXD3↑, 1,   Sp1/3/4↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

miR-143↑, 1,   miR-192-5p↑, 1,   miR-205↑, 1,   miR-21↓, 3,   other↝, 4,   other∅, 1,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

HSP90↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG3↓, 1,   ATG3↑, 1,   ATG5↑, 1,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 1,   LC3I↓, 1,   LC3II↑, 1,   TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

ATR↑, 1,   DNAdam↑, 3,   DNMTs↓, 1,   GADD45A↑, 1,   P53?, 1,   P53↑, 2,   p‑P53↑, 1,   p53 Wildtype↓, 1,   cl‑PARP↑, 3,   p‑γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 7,   P21↑, 6,   TAp63α↑, 1,   TumCCA↓, 2,   TumCCA↑, 11,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

AXIN1↓, 1,   CD24↓, 1,   CD44↓, 1,   CSCs↓, 4,   EMT↓, 4,   ERK↓, 1,   FOXM1↓, 1,   Gli1↓, 2,   GSK‐3β↓, 1,   HDAC↓, 1,   HDAC4↓, 1,   HH↓, 4,   IGF-1↓, 1,   miR-34a↑, 1,   miR-99↑, 1,   mTOR↓, 2,   p‑mTOR↓, 1,   NKD2↑, 2,   NOTCH1↓, 2,   NOTCH1↝, 1,   PI3K↓, 3,   PTEN↑, 1,   Shh↓, 3,   Smo↓, 1,   Src↓, 1,   STAT↓, 1,   STAT3↓, 4,   p‑STAT3↓, 1,   TCF↓, 2,   TumCG↓, 11,   Wnt↓, 3,  

Migration(tgid=13) ⓘ

AP-1↓, 1,   AP-1↝, 1,   CDK4/6↓, 1,   E-cadherin↓, 1,   E-cadherin↑, 3,   FAK↓, 1,   miR-130a↓, 2,   MMP2↓, 4,   MMP9↓, 4,   MMPs↓, 1,   N-cadherin↓, 1,   NEDD9↓, 1,   Rho↓, 1,   TET1↑, 1,   TumCI↓, 11,   TumCMig↓, 15,   TumCP↓, 51,   TumMeta↓, 4,   TumMeta↑, 2,   Vim↓, 1,   Vim↑, 1,   β-catenin/ZEB1↓, 6,   p‑β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 4,   Hif1a↓, 2,   Hif1a↝, 1,   Hypoxia↓, 1,   VEGF↓, 2,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↓, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   COX2/PTGS2↑, 1,   IKKα↓, 1,   Inflam↓, 1,   JAK↓, 1,   JAK2↓, 1,   NF-kB↓, 8,  

Cellular Microenvironment(tgid=17) ⓘ

e-pH↑, 1,   i-pH↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

ChE↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 2,   ERα/ESR1↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 3,   BioAv↑, 3,   ChemoSen↑, 3,   Dose↝, 3,   eff↓, 3,   eff↑, 13,   Half-Life↓, 2,   Half-Life↑, 1,   RadioS↑, 3,   selectivity↑, 4,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↑, 1,   Albumin↑, 1,   ALP↑, 1,   AR↓, 2,   AST↑, 1,   ERα/ESR1↓, 1,   FOXM1↓, 1,   Myc↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 2,   chemoPv↑, 3,   fatigue↓, 1,   OS↑, 2,   toxicity↓, 1,   toxicity↑, 1,   toxicity↝, 3,   toxicity∅, 1,   TumVol↓, 2,   TumVol↑, 1,   TumW↓, 1,  
Total Targets: 205

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 2,   ROS↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Inflam↓, 1,   Inflam↑, 1,  

Functional Outcomes(tgid=23) ⓘ

chemoPv↑, 1,  
Total Targets: 6

Scientific Paper Hit Count for: TumCP, Tumor Cell proliferation
44 Curcumin
25 Quercetin
24 Thymoquinone
23 Shikonin
19 Magnetic Fields
19 EGCG (Epigallocatechin Gallate)
18 Berberine
18 Resveratrol
18 Sulforaphane (mainly Broccoli)
17 Kaempferol
17 Licochalcone A
16 Baicalein
14 Silver-NanoParticles
14 Apigenin (mainly Parsley)
14 Capsaicin
14 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
14 Phenethyl isothiocyanate
13 Formononetin
13 Honokiol
12 Artemisinin
12 Fisetin
12 Garcinol
12 Propolis -bee glue
11 Ashwagandha(Withaferin A)
11 Astaxanthin
11 Radiotherapy/Radiation
11 Boron
11 Crocetin
11 Emodin
11 Juglone
11 Lycopene
11 Nimbolide
10 Cisplatin
10 Chrysin
10 Metformin
10 Magnolol
10 itraconazole
10 Luteolin
10 Selenite (Sodium)
10 Silymarin (Milk Thistle) silibinin
10 Urolithin
9 Berbamine
9 Gallic acid
9 Hyperoside
9 Ivermectin
8 Citric Acid
8 chitosan
8 Beta-Caryophyllene
8 chaetocin
8 Dandelion Root
8 HydroxyTyrosol
8 Isobavachalcone
7 Astragalus
7 Anethole/trans-Anethole
7 5-fluorouracil
7 Bufalin/Huachansu
7 Centella asiatica / Gotu kola → asiaticoside
7 Eugenol
7 Ferulic acid
7 Gambogic Acid
7 Ginkgetin
7 Isoliquiritigenin
7 isoorientin
7 Piperlongumine
6 Boswellia (frankincense)
6 Chemotherapy
6 Carnosic acid
6 Rosmarinic acid
6 Celastrol
6 Carvone
6 Cucurbitacin
6 Diclofenac
6 Ellagic acid
6 Evodiamine
6 isoquercitrin
6 Lemongrass Extract/Citral
6 Phenylbutyrate
6 salinomycin
5 DTS(dibenzyl trisulphide) from Anamu
5 Gemcitabine (Gemzar)
5 Betulinic acid
5 Carvacrol
5 Cinnamon
5 Copper and Cu NanoParticles
5 Deguelin
5 D-limonene
5 Fucoidan
5 Galloflavin
5 Geraniol
5 Hydrogen Gas
5 Helleborus niger extracts – Christmas Rose
5 Vitamin K2
4 Allicin (mainly Garlic)
4 Melatonin
4 Paclitaxel/Taxol
4 Atorvastatin
4 brusatol
4 Celecoxib
4 Chlorogenic acid
4 Chlorophyllin
4 Photodynamic Therapy
4 Date Fruit Extract
4 Disulfiram
4 Genistein (soy isoflavone)
4 Fenbendazole
4 Ginger/6-Shogaol/Gingerol
4 Indole-3-carbinol
4 iodine
4 Inositol
4 Magnetic Field Rotating
4 Piperine
4 Ursolic acid
3 1,8-Cineole
3 Alpha-Lipoic-Acid
3 Andrographis
3 Isovitexin
3 Aspirin
3 immunotherapy
3 Docetaxel
3 α-Bisabolol / Chamomile oil
3 Butyrate
3 Caffeic acid
3 Thymol-Thymus vulgaris
3 Chocolate
3 Cichoric acid / Chicoric acid
3 Cyclopamine
3 Cynaropicrin
3 Dichloroacetate
3 diet Methionine-Restricted Diet
3 Ginkgo biloba-EGb 761
3 Ginkgo biloba
3 Ginkgolide B
3 Vitamin C (Ascorbic Acid)
3 Licorice
3 Lactoferrin/Talactoferrin
3 Linalool
3 Methylene blue
3 Oleuropein
3 Propyl gallate
3 Plumbagin
3 Pterostilbene
3 Selenium
3 Terpinen-4-ol / Tea Tree Oil
3 Aflavin-3,3′-digallate
3 VitK3,menadione
3 Zerumbone
2 Sorafenib (brand name Nexavar)
2 Auranofin
2 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
2 Ascorbyl Palmitate
2 Arctigenin
2 Baicalin
2 Biochanin A
2 Brucea javanica
2 Bacopa monnieri
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Hydroxycinnamic-acid
2 Coenzyme Q10
2 Carica papaya leaf extract
2 Cynara scolymus/Globe Artichoke/Artichoke Extract
2 Dichloroacetophenone(2,2-)
2 diet FMD Fasting Mimicking Diet
2 diet Short Term Fasting
2 Echinacea
2 Eurycomanone
2 Arsenic trioxide
2 Ginkgolic acids
2 γ-linolenic acid (Borage Oil)
2 Graviola
2 Grapeseed extract
2 hydrogen sulfide
2 doxorubicin
2 Laetrile B17 Amygdalin
2 lambertianic acid
2 Lapachol
2 Naringin
2 Niclosamide (Niclocide)
2 Psoralidin
2 EMF
2 Rutin
2 α-Santalol/Sandalwood oil
2 Sulfasalazine
2 Salvia miltiorrhiza
2 Vitamin D3
1 2-DeoxyGlucose
1 3-bromopyruvate
1 Glucose
1 SonoDynamic Therapy UltraSound
1 Zinc
1 Ajoene (compound of Garlic)
1 alpha Linolenic acid
1 Fennel Oil/Foeniculum vulgare
1 Aloe anthraquinones
1 beta-glucans
1 almonertinib
1 bempedoic acid
1 Bevacizumab (brand Avastin)
1 temozolomide
1 Bromelain
1 borneol
1 Bortezomib
1 Bruteridin(bergamot juice)
1 Bullatacin
1 hydroxychloroquine
1 Cat’s Claw
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Cannabidiol
1 Camptothecin
1 irinotecan
1 CUSP9
1 Dasatinib/Phyrago
1 Dihydrocaffeic Acid
1 Electrical Pulses
1 Exercise
1 Vitamin E
1 ferumoxytol
1 Vitamin A, Retinoic Acid
1 Shilajit/Fulvic Acid
1 Ginseng
1 Germacranolide sesquiterpene lactone
1 Siegesbeckia glabrescens
1 HydroxyCitric Acid
1 epipolythiodioxopiperazine / epipolythiopiperazine-2,5-dione
1 Hibiscus sabdariffa
1 Hops (Humulus lupulus)
1 Hyperthermia
1 Inoscavin A
1 Recombinant Methioninase
1 Lactobacillus
1 Caffeine
1 Mushroom Chaga
1 nicotinamide adenine dinucleotide
1 Bicarbonate(Sodium)
1 Oroxylin A
1 Oleocanthal
1 Proanthocyanidins
1 sericin
1 xanthohumol
1 Gold NanoParticles
1 Rauwolfia serpentina/Indian Snakeroot
1 buckwheat sprouts
1 Oxaliplatin
1 Selenium NanoParticles
1 diet Plant based
1 Spermidine
1 tetrathiomolybdate
1 Tumor Treating Fields
1 Turmerones
1 Usnic acid
1 Vitexin
1 Wogonin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:327  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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