Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
378- AgNPs,    Antitumor efficacy of silver nanoparticles reduced with β-D-glucose as neoadjuvant therapy to prevent tumor relapse in a mouse model of breast cancer
- ex-vivo, BC, 4T1
TumVol↓, TumMeta↓, Ki-67↓,
379- AgNPs,    Effects of green-synthesized silver nanoparticles on lung cancer cells in vitro and grown as xenograft tumors in vivo
- in-vivo, Lung, H1299
NF-kB↓, Bcl-2↓, Casp3↑, survivin↑, TumCG↓,
380- AgNPs,  QC,  CA,  Chit,    Quercetin- and caffeic acid-functionalized chitosan-capped colloidal silver nanoparticles: one-pot synthesis, characterization, and anticancer and antibacterial activities
- in-vitro, MG, U118MG
TumCG↓,
381- AgNPs,    Silver Nanoparticles Exert Apoptotic Activity in Bladder Cancer 5637 Cells Through Alteration of Bax/Bcl-2 Genes Expression
- in-vitro, Bladder, 5637
ROS↑, BAX↑, Bcl-2↓, Casp3↑, Casp7↑, Apoptosis↑,
382- AgNPs,    Investigation the apoptotic effect of silver nanoparticles (Ag-NPs) on MDA-MB 231 breast cancer epithelial cells via signaling pathways
- in-vitro, BC, MDA-MB-231
Apoptosis↑, BAX↑, Bcl-2↓, P53↑, PTEN↑, hTERT/TERT↓, p‑ERK↓, cycD1/CCND1↓,
383- AgNPs,    In vitro and in vivo evaluation of anti-tumorigenesis potential of nano silver for gastric cancer cells
- in-vitro, GC, MKN45
Ki-67↓, TumCP↓, CD34↓, BAX↑,
385- AgNPs,    Probiotic-derived silver nanoparticles target mTOR/MMP-9/BCL-2/dependent AMPK activation for hepatic cancer treatment
- in-vitro, Hepat, HepG2 - in-vitro, Hepat, WI38
TNF-α↑, IL33↑, mTOR↓, MMP9↓, Bcl-2↓, ROS↑, Apoptosis↑,
386- AgNPs,  Tam,    Synergistic anticancer effects and reduced genotoxicity of silver nanoparticles and tamoxifen in breast cancer cells
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231
P53↑, BAX↑, Bcl-2↓, Casp3↑, DNAdam↑, TumCCA↑,
387- AgNPs,    Silver nanoparticles induce mitochondria-dependent apoptosis and late non-canonical autophagy in HT-29 colon cancer cells
- in-vitro, Colon, HT-29
Cyt‑c↑, P53↑, BAX↑, Casp3↑, Casp9↑, Casp12↑, Beclin-1/ATG6↑, CHOP/DDIT3↑, LC3s↑, XBP-1↑,
388- AgNPs,    Apoptotic efficacy of multifaceted biosynthesized silver nanoparticles on human adenocarcinoma cells
- in-vitro, BC, MCF7
ROS↑, Casp3↑, BAX↑, P53↑, Casp↑, Cyt‑c↑, MMP↓, DNAdam↑, Bcl-2↓, BAX↑,
390- AgNPs,    Anti-cancerous effect of albumin coated silver nanoparticles on MDA-MB 231 human breast cancer cell line
- in-vitro, BC, MDA-MB-231 - in-vivo, BC, NA
ROS↑, TumVol↓,
384- AgNPs,    Dual functions of silver nanoparticles in F9 teratocarcinoma stem cells, a suitable model for evaluating cytotoxicity- and differentiation-mediated cancer therapy
- in-vitro, Testi, F9
LDH↓, ROS↑, mtDam↑, DNAdam↑, P53↑, P21↑, BAX↑, Casp3↑, Bcl-2↓, Casp9↑, Nanog↓, OCT4↓,
2288- AgNPs,    Silver Nanoparticle-Mediated Cellular Responses in Various Cell Lines: An in Vitro Model
- Review, Var, NA
*ROS↑, Akt↓, ERK↓, DNAdam↑, Ca+2↑, ROS↑, MMP↓, Cyt‑c↑, TumCCA↑, DNAdam↑, Apoptosis↑, P53↑, p‑ERK↑, ER Stress↑, cl‑ATF6↑, GRP78/BiP↑, CHOP/DDIT3↑, UPR↑,
2287- AgNPs,    Silver nanoparticles induce endothelial cytotoxicity through ROS-mediated mitochondria-lysosome damage and autophagy perturbation: The protective role of N-acetylcysteine
- in-vitro, Nor, HUVECs
*TumCP↓, *ROS↑, *eff↓, *MDA↑, *GSH↓, *MMP↓, *ATP↓, *LC3II↑, *p62↑, *Bcl-2↓, *BAX↑, *Casp3↑,
2286- AgNPs,    Short-term changes in intracellular ROS localisation after the silver nanoparticles exposure depending on particle size
- in-vitro, Nor, 3T3
*eff↑, *mt-ROS↑, *eff↑,
2837- AgNPs,    Trojan-Horse Mechanism in the Cellular Uptake of Silver Nanoparticles Verified by Direct Intra- and Extracellular Silver Speciation Analysis
- in-vitro, NA, NA
eff↑,
2836- AgNPs,  Gluc,    Glucose capped silver nanoparticles induce cell cycle arrest in HeLa cells
- in-vitro, Cerv, HeLa
eff↝, TumCCA↑, eff↑, eff↑, ROS↑, GSH↓, SOD↓, lipid-P↑, LDH↑,
2835- AgNPs,  Gluc,    Carbohydrate functionalization of silver nanoparticles modulates cytotoxicity and cellular uptake
- in-vitro, Liver, HepG2
Dose↝, eff↑, ROS↑, eff↝, eff↑, eff↝, eff↑, eff↝,
2834- AgNPs,  Gluc,    Electrochemical oxidation of glucose on silver nanoparticle-modified composite electrodes
- Study, NA, NA
Dose?,
2208- AgNPs,    Sepsis diagnosis and treatment using nanomaterials
- Review, NA, NA
Bacteria↓,
2207- AgNPs,  TQ,    Protective effects of Nigella sativa L. seeds aqueous extract-based silver nanoparticles on sepsis-induced damages in rats
- in-vivo, Nor, NA
*eff↑, *RenoP↑, *hepatoP↑, *MDA↓, *SOD↑, *GSH↑, *TNF-α↓, *IL1β↓,
2206- AgNPs,  RES,    ENHANCED EFFICACY OF RESVERATROL-LOADED SILVER NANOPARTICLE IN ATTENUATING SEPSIS-INDUCED ACUTE LIVER INJURY: MODULATION OF INFLAMMATION, OXIDATIVE STRESS, AND SIRT1 ACTIVATION
- in-vivo, Nor, NA
*hepatoP↑, *Inflam↓, *NF-kB↓, *VEGF↓, *SIRT1↑, *ROS↓, *Dose↝, *Catalase↑, *MDA↓, *MPO↓, *NO↓, *ALAT↓, *AST↓, *antiOx↑,
2205- AgNPs,    Potential protective efficacy of biogenic silver nanoparticles synthesised from earthworm extract in a septic mice model
- in-vivo, Nor, NA
*Dose↝, *eff↑, *RenoP↑, *antiOx↑, *MDA↓, *NO↓, *hepatoP↑, *toxicity↝, *GSH↑, *SOD↑, *GSTs↑, *Catalase↑,
2538- AgNPs,  SDT,  Z,    Dual-functional silver nanoparticle-enhanced ZnO nanorods for improved reactive oxygen species generation and cancer treatment
- Study, Var, NA - vitro+vivo, NA, NA
ROS↑, eff↑, eff↑, TumCP↓, toxicity↓,
2539- AgNPs,  SDT,    Combined effect of silver nanoparticles and therapeutical ultrasound on ovarian carcinoma cells A2780
- in-vitro, Melanoma, A2780S
tumCV↓, sonoP↑, BioEnh↑,
7426- AgNPs,  CS,    Silver Nanoparticles Formulation of Flower Head's Polyphenols of Cynara scolymus L.: A Promising Candidate against Prostate (PC-3) Cancer Cell Line through Apoptosis Activation
- in-vitro, Pca, PC3 - in-vitro, Lung, A549
*antiOx↑, tumCV↓, eff↑, Dose↝, P53↑, BAX↑, Casp3↑, Casp8↑, Casp9↑, Bcl-2↓,
7292- Aidi,    Chinese patent medicine Aidi injection for cancer care: An overview of systematic reviews and meta-analyses
- Review, Var, NA
eff?,
5340- Ajoene,    Ajoene, a compound of garlic, induces apoptosis in human promyeloleukemic cells, accompanied by generation of reactive oxygen species and activation of nuclear factor kappaB
- in-vitro, AML, NA
Apoptosis↑, selectivity↑, H2O2↑, NF-kB↑,
5341- Ajoene,    Ajoene (natural garlic compound): a new anti-leukaemia agent for AML therapy
- Review, AML, NA
eff↑, AntiThr↑, Bacteria↓, LDH↓, TumCP↓, TumCCA↑, Bcl-2↓, Cyt‑c↑, Casp3↑,
5342- Ajoene,    The garlic-derived organosulfur component ajoene decreases basal cell carcinoma tumor size by inducing apoptosis
- in-vivo, BCC, NA
TumVol↓, Bcl-2↓, Apoptosis↑,
5343- Ajoene,    The garlic compound ajoene covalently binds vimentin, disrupts the vimentin network and exerts anti-metastatic activity in cancer cells
- in-vitro, Cerv, HeLa - in-vitro, BC, MDA-MB-231
Vim↑, TumCI↓, TumCMig↓, TumMeta↓, Vim↓, other↝,
5344- Ajoene,    Ajoene, a Stable Garlic By-Product, Has an Antioxidant Effect through Nrf2-Mediated Glutamate-Cysteine Ligase Induction in HepG2 Cells and Primary Hepatocytes
- in-vitro, Nor, HepG2
*Nrf1↑, *PKCδ↑, *GSH↑, *antiOx↑,
252- Ajoene,    Ajoene, a Compound of Garlic, Induces Apoptosis in Human Promyeloleukemic Cells, Accompanied by Generation of Reactive Oxygen Species and Activation of Nuclear Factor κB
- in-vitro, AML, HL-60
H2O2↑, NF-kB↑, ROS↑,
540- Akk,    Akkermansia muciniphila: a potential booster to improve the effectiveness of cancer immunotherapy
- Analysis, NA, NA
GutMicro↑, carcinogenesis↓, ChemoSideEff↓,
541- Akk,    Akkermansia muciniphila as a Next-Generation Probiotic in Modulating Human Metabolic Homeostasis and Disease Progression: A Role Mediated by Gut-Liver-Brain Axes?
- Review, NA, NA
GutMicro↑, PD-1↝, CD8+↑, IL8↑,
542- Akk,  immuno,    Gut microbiome influences efficacy of PD-1-based immunotherapy against epithelial tumors
CD4+↑, CXCc↑, PD-1↝,
543- Akk,    Dynamic Changes of the Gut Microbiota and Its Functional Metagenomic Potential during the Development of Non-Small Cell Lung Cancer
other↓,
4- Akk,    The Emerging Biotherapeutic Agent: Akkermansia
- Review, Var, NA
GutMicro↑,
5350- Akk,  immuno,    Enhancing Immune Response in Immunotherapy-Resistant Melanoma Through Fecal Microbiota Transplantation: A Systematic Review
eff↑,
5351- Akk,    Akkermansia muciniphila supplementation in patients with overweight/obese type 2 diabetes: Efficacy depends on its baseline levels in the gut
- Human, Diabetic, NA
GutMicro↑, Weight↓,
5349- Akk,  immuno,    Improved survival in advanced melanoma patients treated with fecal microbiota transplantation using healthy donor stool in combination with anti-PD1: final results of the MIMic phase 1 trial
- Case Report, Melanoma, NA
eff↑, OS↑, eff↑,
5348- Akk,  immuno,    Gut Microbiota Modulation through Akkermansia spp. Supplementation Increases CAR T-cell Potency
- Human, Var, NA
other↑, eff↑,
5347- Akk,  immuno,    Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer
- Human, NSCLC, NA
eff↑,
5346- Akk,  immuno,    Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors
- in-vivo, Var, NA
eff↑,
5353- AL,    Aged Garlic Extract May Be Safe for Patients on Warfarin Therapy
- Human, Nor, NA
*AntiAg↑, *toxicity↓, *cardioP↑, *Dose↝,
5352- AL,    Anticancer potential of allicin: A review
- Review, Var, NA
*cardioP↑, *Bacteria↓, *Inflam↓, AntiTum↑, *DNAdam↓, TumCP↓, angioG↓, TumMeta↓,
5356- AL,    Therapeutic role of allicin in gastrointestinal cancers: mechanisms and safety aspects
- Review, GC, NA
Apoptosis↑, TumCP↓, MAPK↓, PI3K↓, Akt↓, NF-kB↓, AntiCan↑, ChemoSen↑, TumCCA↑, Apoptosis↑, BioAv↑, selectivity↑, TGF-β↓, ROS↑, DNAdam↑, p‑P53↑, P21↑, cycD1/CCND1↓, cycE/CCNE↓, CDK4↓, CDK6↓, MMP↓, NF-kB↑, BAX↑, Bcl-2↓, ER Stress↑, Casp↑, AIF↑, Fas↑, Casp8↑, Cyt‑c↑, cl‑PARP↑, Ca+2↑, *NRF2↑, *chemoP↑, *GutMicro↑, CycB/CCNB1↑, H2S↑, HIF-1↓, RadioS↑,
5355- AL,    Mini-review: The health benefits and applications of allicin
- Review, Var, NA
*BioAv↑, *cardioP↑, *hepatoP↑, *RenoP↑, *Half-Life↝, *BioAv↓, *neuroP↑, *cognitive↑, *ROS↓, *lipid-P↓, *DNArepair↑, *ChemoSen↑,
5354- AL,    Therapeutic Potential of Allicin-Rich Garlic Preparations: Emphasis on Clinical Evidence toward Upcoming Drugs Formulation
- Review, Var, NA
*LDL↓, *antiOx↑, AntiCan↑, *cardioP↑, *BP↓, *Weight↓, NK cell↑, *AntiDiabetic↑, *GSH↑,
1916- AL,    Allicin Bioavailability and Bioequivalence from Garlic Supplements and Garlic Foods
- Review, Nor, NA
*BioAv↝, *eff↓, *BioAv↝, *BioAv↝, *eff↑, *Half-Life∅, *eff↑, *eff↑, *Dose∅, *eff↑,

Showing Research Papers: 401 to 450 of 8263
Prev Page 9 of 166 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 8263

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1)

GSH↓, 1,   H2O2↑, 2,   lipid-P↑, 1,   ROS↑, 11,   SOD↓, 1,  

Mitochondria & Bioenergetics(tgid=3)

AIF↑, 1,   MMP↓, 3,   mtDam↑, 1,  

Core Metabolism/Glycolysis(tgid=4)

H2S↑, 1,   LDH↓, 2,   LDH↑, 1,  

Cell Death(tgid=5)

Akt↓, 2,   Apoptosis↑, 8,   BAX↑, 10,   Bcl-2↓, 11,   Casp↑, 2,   Casp12↑, 1,   Casp3↑, 8,   Casp7↑, 1,   Casp8↑, 2,   Casp9↑, 3,   Cyt‑c↑, 5,   Fas↑, 1,   hTERT/TERT↓, 1,   MAPK↓, 1,   survivin↑, 1,  

Transcription & Epigenetics(tgid=7)

AntiThr↑, 1,   carcinogenesis↓, 1,   other↓, 1,   other↑, 1,   other↝, 1,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8)

cl‑ATF6↑, 1,   CHOP/DDIT3↑, 2,   ER Stress↑, 2,   GRP78/BiP↑, 1,   UPR↑, 1,   XBP-1↑, 1,  

Autophagy & Lysosomes(tgid=9)

Beclin-1/ATG6↑, 1,   LC3s↑, 1,  

DNA Damage & Repair(tgid=10)

DNAdam↑, 6,   P53↑, 7,   p‑P53↑, 1,   cl‑PARP↑, 1,  

Cell Cycle & Senescence(tgid=11)

CDK4↓, 1,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 2,   cycE/CCNE↓, 1,   P21↑, 2,   TumCCA↑, 5,  

Proliferation, Differentiation & Cell State(tgid=12)

CD34↓, 1,   ERK↓, 1,   p‑ERK↓, 1,   p‑ERK↑, 1,   mTOR↓, 1,   Nanog↓, 1,   OCT4↓, 1,   PI3K↓, 1,   PTEN↑, 1,   TumCG↓, 2,  

Migration(tgid=13)

Ca+2↑, 2,   Ki-67↓, 2,   MMP9↓, 1,   TGF-β↓, 1,   TumCI↓, 1,   TumCMig↓, 1,   TumCP↓, 5,   TumMeta↓, 3,   Vim↓, 1,   Vim↑, 1,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 1,   HIF-1↓, 1,  

Barriers & Transport(tgid=15)

sonoP↑, 1,  

Immune & Inflammatory Signaling(tgid=16)

CD4+↑, 1,   CXCc↑, 1,   IL33↑, 1,   IL8↑, 1,   NF-kB↓, 2,   NF-kB↑, 3,   NK cell↑, 1,   PD-1↝, 2,   TNF-α↑, 1,  

Hormonal & Nuclear Receptors(tgid=20)

CDK6↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↑, 1,   BioEnh↑, 1,   ChemoSen↑, 1,   Dose?, 1,   Dose↝, 2,   eff?, 1,   eff↑, 16,   eff↝, 4,   RadioS↑, 1,   selectivity↑, 2,  

Clinical Biomarkers(tgid=22)

GutMicro↑, 4,   hTERT/TERT↓, 1,   Ki-67↓, 2,   LDH↓, 2,   LDH↑, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 2,   AntiTum↑, 1,   ChemoSideEff↓, 1,   OS↑, 1,   toxicity↓, 1,   TumVol↓, 3,   Weight↓, 1,  

Infection & Microbiome(tgid=24)

Bacteria↓, 2,   CD8+↑, 1,  
Total Targets: 107

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1)

antiOx↑, 5,   Catalase↑, 2,   GSH↓, 1,   GSH↑, 4,   GSTs↑, 1,   lipid-P↓, 1,   MDA↓, 3,   MDA↑, 1,   MPO↓, 1,   Nrf1↑, 1,   NRF2↑, 1,   ROS↓, 2,   ROS↑, 2,   mt-ROS↑, 1,   SOD↑, 2,  

Mitochondria & Bioenergetics(tgid=3)

ATP↓, 1,   MMP↓, 1,  

Core Metabolism/Glycolysis(tgid=4)

ALAT↓, 1,   LDL↓, 1,   SIRT1↑, 1,  

Cell Death(tgid=5)

BAX↑, 1,   Bcl-2↓, 1,   Casp3↑, 1,  

Autophagy & Lysosomes(tgid=9)

LC3II↑, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10)

DNAdam↓, 1,   DNArepair↑, 1,  

Migration(tgid=13)

AntiAg↑, 1,   PKCδ↑, 1,   TumCP↓, 1,  

Angiogenesis & Vasculature(tgid=14)

NO↓, 2,   VEGF↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

IL1β↓, 1,   Inflam↓, 2,   NF-kB↓, 1,   TNF-α↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 1,   BioAv↑, 1,   BioAv↝, 3,   ChemoSen↑, 1,   Dose↝, 3,   Dose∅, 1,   eff↓, 2,   eff↑, 8,   Half-Life↝, 1,   Half-Life∅, 1,  

Clinical Biomarkers(tgid=22)

ALAT↓, 1,   AST↓, 1,   BP↓, 1,   GutMicro↑, 1,  

Functional Outcomes(tgid=23)

AntiDiabetic↑, 1,   cardioP↑, 4,   chemoP↑, 1,   cognitive↑, 1,   hepatoP↑, 4,   neuroP↑, 1,   RenoP↑, 3,   toxicity↓, 1,   toxicity↝, 1,   Weight↓, 1,  

Infection & Microbiome(tgid=24)

Bacteria↓, 1,  
Total Targets: 61

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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