Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
7632- Ins,    The paradoxical role of inositol in cancer: a consequence of the metabolic state of a tumor
- Review, Var, NA
AMPK↑, AntiCan⇅, p‑Akt↓, PI3K↓,
7633- Ins,    Myo-inositol in a new pharmaceutical form: a step forward to a broader clinical use
- Trial, Nor, NA
*BioAv↑, *toxicity↓,
7673- iod,  Chemo,    Adjuvant Effect of Molecular Iodine in Conventional Chemotherapy for Breast Cancer. Randomized Pilot Study
- Trial, BC, NA
Dose↝, *chemoP↑,
7672- iod,    Adjuvant Effect of Molecular Iodine in Conventional Chemotherapy for Breast Cancer. Randomized Pilot Study
- Trial, BC, NA
Dose↝, OS↑, TumCI↓, Apoptosis↑, EstroRS/ERS↑, eff↑, *cardioP↑, *antiOx↑, *Inflam↓,
7671- iod,    Uptake and antiproliferative effect of molecular iodine in the MCF-7 breast cancer cell line
- in-vitro, BC, MCF7
TumCP↓,
7674- iod,    Molecular iodine induces caspase-independent apoptosis in human breast carcinoma cells involving the mitochondria-mediated pathway
- in-vitro, BC, NA
AntiTum↑, selectivity↑, MMP↓, antiOx↑, Thiols↓, Bcl-2↓, BAX↑, eff↓, Casp↑, ROS↓, ROS↑, Cyt‑c↑, AIF↑,
7676- iod,    Antineoplastic effect of iodine in mammary cancer: participation of 6-iodolactone (6-IL) and peroxisome proliferator-activated receptors (PPAR)
- in-vivo, BC, NA
TumCP↓, Apoptosis↑, Dose↝, other↑, BloodF↓, VEGF↓, UroPA↓, PPARα↓, DR4↑, Casp3↑, PPARγ↑, antiNeop↑, Risk↓, 6IL↑,
7677- iod,    Activation of peroxisome proliferator-activated receptor gamma is crucial for antitumoral effects of 6-iodolactone
- in-vitro, BC, MCF7
TumCP↓, 6IL↑, PPARγ↑, AntiCan↑,
7678- iod,    Signaling pathways involved in the antiproliferative effect of molecular iodine in normal and tumoral breast cells: evidence that 6-iodolactone mediates apoptotic effects
- in-vitro, Nor, MCF12A - in-vitro, BC, MCF7
TumCCA↑, selectivity↑, 6IL↑, eff↑,
7679- iod,    Molecular iodine impairs chemoresistance mechanisms, enhances doxorubicin retention and induces downregulation of the CD44+/CD24+ and E-cadherin+/vimentin+ subpopulations in MCF-7 cells resistant to low doses of doxorubicin
- in-vivo, BC, MCF7
AntiTum↑, tumCV↓, Apoptosis↑, Bax:Bcl2↑, Bcl-2↓, MDR1↑, PPARγ↑, CD44↓,
7680- iod,  doxoR,    Iodine and doxorubicin, a good combination for mammary cancer treatment: antineoplastic adjuvancy, chemoresistance inhibition, and cardioprotection
- vitro+vivo, BC, NA
antiNeop↑, antiOx↑, Dose↝, TumVol↓, PCNA↓, Weight↑, cardioP↑, ChemoSen↑,
7681- iod,  metroC,    Molecular Iodine Improves the Efficacy and Reduces the Side Effects of Metronomic Cyclophosphamide Treatment against Mammary Cancer Progression
- in-vivo, BC, NA
tumCV↓, Imm↑, chemoP↑, Weight↑, TumCG↓, VEGF↓, survivin↓, ChemoSen↑,
7682- iod,    Molecular Iodine Induces Anti- and Pro-Neoplastic Effects in Prostate Cancer Models
- in-vitro, Pca, LNCaP - in-vitro, Pca, DU145 - in-vitro, Pca, PC3
PPARγ↑, antiNeop↑, TumCD↑, TumCI↓, AntiCan⇅, antiOx↑, Inflam↓, Apoptosis↑, tumCV↓,
7683- iod,  Se,    Prediagnostic serum iodine and selenium in relation to breast cancer survival
- Study, BC, NA
OS↑, other⇅,
7684- iod,    Molecular iodine impairs chemotherapy resistance and adverse effects in breast cancer treatments
- Trial, BC, NA
Dose↝, OS↑, antiNeop↑, eff↑,
7685- iod,    Could iodine be the missing micronutrient in breast cancer development?
- Review, BC, NA
Risk↓, other↝, other↝, BioAv↝,
7686- iod,    Molecular Iodine Exhibited Differential Antiproliferative Actions in Progenitor and Stem Populations from Chemoresistant Cancer Cells
- vitro+vivo, BC, MCF7
PPARγ↑, Apoptosis↑, Bax:Bcl2↑, CSCs↓, NRF2↑, tumCV↓, TumCI↓,
7687- iod,  ESWT,    Shock Wave Application Increases the Antineoplastic Effect of Molecular Iodine Supplement in Breast Cancer Xenografts
- in-vivo, BC, MDA-MB-231
antiNeop↑, CSCsMark↓, CD44↓, SOX2↓, HIF-1↓, VEGF↓, Dose↝, Dose↝, EPR↝, PPARγ↑,
7688- iod,  CEL,    Iodine prevents the increase of testosterone-induced oxidative stress in a model of rat prostatic hyperplasia
- in-vivo, Pca, NA
TumCP↓, ROS↓, NOS2↓, COX2/PTGS2↓,
7689- iod,    Uptake and antitumoral effects of iodine and 6-iodolactone in differentiated and undifferentiated human prostate cancer cell lines
- in-vitro, Nor, RWPE-1 - in-vitro, Pca, LNCaP - vitro+vivo, Pca, DU145
Bax:Bcl2↑, Casp↑, TumCG↓,
2172- iod,    A prospective study of iodine status, thyroid function, and prostate cancer risk: follow-up of the First National Health and Nutrition Examination Survey
- Study, Pca, NA
Risk↓,
7652- IP,    Inulin prebiotic reinforces host cancer immunosurveillance via ɣδ T cell activation
- in-vivo, Melanoma, B16-F10
GutMicro↑, Imm↑, CD4+↑, CD8+↑, TumCG↓,
7654- IP,    Dietary Supplementation of Inulin Contributes to the Prevention of Estrogen Receptor-Negative Mammary Cancer by Alteration of Gut Microbial Communities and Epigenetic Regulations
- in-vivo, BC, NA
TumCG↓, GutMicro↑, PA↑, HDAC2↓, HDAC8↓, DNMT3B↓, Akt↓, PI3K↓, NF-kB↓, Dose↝, Dose↝,
7669- IP,    Colorectal cancer and inulin supplementation: the good, the bad, and the unhelpful
- Review, CRC, NA
GutMicro↑, Buty↑, eff↓, Inflam↑, eff∅, SCFAs↑,
7653- IP,    Generation of systemic antitumour immunity via the in situ modulation of the gut microbiome by an orally administered inulin gel
- in-vivo, Var, NA
GutMicro↑, T-Cell↑, AntiTum↑, eff↑, TumCG↓,
7655- IP,  SFN,    Combined Phytochemical Sulforaphane and Dietary Fiber Inulin Contribute to the Prevention of ER-Negative Breast Cancer via PI3K/AKT/MTOR Pathway and Modulating Gut Microbial Composition
- in-vivo, BC, NA
Dose↝, TumCG↓, TumW↓, GutMicro↑, HDAC↓, DNMTs↓, Akt↓, PI3K↓, mTOR↓, NF-kB↓, TumCCA↑, cl‑Casp3↑, cl‑Casp7↑, CDK2↓, CDK4↓, Risk↓, Dose↝,
7656- IP,    Inulin Modulates Gut Microbiota and Increases Short-Chain Fatty Acids Levels to Inhibit Colon Tumorigenesis in Rat Models: A Systematic Review and Meta-Analysis
- Review, CRC, NA
GutMicro↑, chemoPv↑, SCFAs↑,
7657- IP,    Dietary inulin suppresses azoxymethane-induced aberrant crypt foci and colon tumors at the promotion stage in young Fisher 344 rats
- in-vivo, Var, NA
Dose↝, AntiTum↑,
7658- IP,    Effect of dietary oligofructose and inulin on colonic preneoplastic aberrant crypt foci inhibition
- in-vivo, CRC, NA
AntiTum↑, GutMicro↑,
7659- IP,    Inulin-type fructans and reduction in colon cancer risk: review of experimental and human data
- in-vivo, Colon, NA
GutMicro↑, SCFAs↑, eff↑, Buty↑, Risk↓,
7660- IP,    Overview of experimental data on reduction of colorectal cancer risk by inulin-type fructans
- Review, CRC, NA
SCFAs↑, Buty↑, PA↑, TumCG↓, HDAC↓, Apoptosis↑, TumMeta↓,
7661- IP,    Enhancement of carbohydrate metabolism by probiotic and prebiotic intake promotes short-chain fatty acid production in the gut microbiome: a randomized, double-blind, placebo-controlled crossover trial
- Trial, Nor, NA
*PA↑, *Buty↑, *GutMicro↑, *SCFAs↑,
7662- IP,    Digestive tolerance of inulin-type fructans: a double-blind, placebo-controlled, cross-over, dose-ranging, randomized study in healthy volunteers
- Trial, Nor, NA
Dose↝, toxicity↓,
7663- IP,    Industrial additive and dietary fiber inulin induces tumor-selective necrotic death via mitochondrial lipid peroxidation involving MYC and YAP
GutMicro↑, lipid-P↑, mtDam↑, eff↑, Myc↓, YAP/TEAD↓, AR↑,
7664- IP,  GCL2505,    Administration of bifidobacteria and dietary fiber improves cognitive function by increasing short-chain fatty acid-producing bacteria and reducing inflammation
- Trial, AD, NA
*cognitive↑, *SCFAs↑, *GutMicro↑, *Buty↑, *AcOH↑, *neuroP↑,
7665- IP,    A Prebiotic-Supplemented Formula Improves Gut Microbiota and Intestinal Inflammatory Microenvironment in Patients with Colorectal Adenoma: A Double-Blind, Placebo-Controlled Trial
- Trial, Nor, NA
*GutMicro↑, *Inflam↓,
7666- IP,    Short-chain fatty acid kinetics and concentrations are higher after inulin supplementation in young and older adults: a randomized trial
- Trial, Nor, NA
*Dose↝, *Buty↑, *PA↑, *AcOH↑, *SCFAs↑,
7667- IP,  H2,    Molecular hydrogen as a potential mediator of the antitumor effect of inulin consumption
*AntiTum↑, *other↑, *NA↝, *CD4+↑, *CD8+↑, TumCG↓, Imm↑,
7668- IP,    A phase 2 randomized, placebo-controlled trial of inulin for the prevention of gut pathogen colonization and infection among patients admitted to the intensive care unit for sepsis
- Trial, Sepsis, NA
*Dose↝, *SCFAs∅, *GutMicro∅, *other↝,
7697- IP6,  Ins,    Combination of Inositol Hexaphosphate and Inositol Inhibits Liver Metastasis of Colorectal Cancer in Mice Through the Wnt/β-Catenin Pathway
- in-vivo, CRC, NA
TumMeta↓, OS↑, TumW↓, Wnt↓, TCF7/TCF1↓, cMyc↓,
7713- IP6,  PacT,    Inositol hexaphosphate and paclitaxel: symbiotic treatment of oral cavity squamous cell carcinoma
- in-vitro, Oral, Ca9-22 - in-vitro, Oral, HN5
NF-kB↓, ChemoSen↑, TumCP↓, TumCD↑, Apoptosis↑,
7714- IP6,  ACNs,    Enhanced absorption of anthocyanins after oral administration of phytic acid in rats and humans
- in-vivo, Nor, NA
*BioEnh↑, *BioAv↑, *Dose↝,
7715- IP6,    Inositol hexaphosphate (IP6) inhibits cellular proliferation in melanoma
- in-vitro, Melanoma, HTB68
TumCP↓, VEGF↓, Apoptosis↑,
7716- IP6,    Inositol hexaphosphate (IP6): a novel treatment for pancreatic cancer
- in-vitro, Pca, MIA PaCa-2 - in-vitro, PC, PANC1
TumCP↓, Apoptosis↑,
7717- IP6,    In vivo suppression of hormone-refractory prostate cancer growth by inositol hexaphosphate: induction of insulin-like growth factor binding protein-3 and inhibition of vascular endothelial growth factor
- in-vivo, Pca, DU145
TumCG↓, IGFBP3↑, VEGF↓, TumCP↓, angioG↓,
7712- IP6,    Chemopreventive efficacy of inositol hexaphosphate against prostate tumor growth and progression in TRAMP mice
- in-vivo, Pca, NA
toxicity↓, PCNA↓, TumCG↓, TumCP↓, Apoptosis↑, Risk↓,
7718- IP6,    Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes
- in-vitro, Pca, DU145
chemoPv↑, TumCG↓, TumCCA↑, P21↓, p27/CDKN1B↑, CDK2↓, CDK4↓, CDK6↓, cycE/CCNE↓, cycD1/CCND1↓, pRB↑, Apoptosis↑, cl‑PARP↑, Casp3↑,
7719- IP6,    Effect of inositol hexaphosphate (IP(6)) on human normal and leukaemic haematopoietic cells
- in-vitro, CML, NA
TumCD↑, TumCCA↑, selectivity↑, TumCP↓,
7720- IP6,    Protective effect of phytic acid on oxidative DNA damage with reference to cancer chemoprevention
- Review, Nor, NA
*ROS?, *IronCh↑, *chemoPv↑,
7721- IP6,  Ins,    Effect of phytic acid and inositol on the proliferation and apoptosis of cells derived from colorectal carcinoma
- in-vitro, CRC, HT-29 - in-vitro, CRC, SW480 - in-vitro, CRC, SW-620
Dose↝, TumCP↓, Casp3↑, Apoptosis↑,

Showing Research Papers: 4901 to 4950 of 8269
Prev Page 99 of 166 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 8269

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

6IL↑, 3,   Buty↑, 3,   PA↑, 2,   SCFAs↑, 4,   TCF7/TCF1↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 3,   lipid-P↑, 1,   NRF2↑, 1,   ROS↓, 2,   ROS↑, 1,   Thiols↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 1,   MMP↓, 1,   mtDam↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 1,   cMyc↓, 1,   PPARα↓, 1,   PPARγ↑, 6,  

Cell Death(tgid=5) ⓘ

Akt↓, 2,   p‑Akt↓, 1,   Apoptosis↑, 12,   BAX↑, 1,   Bax:Bcl2↑, 3,   Bcl-2↓, 2,   Casp↑, 2,   Casp3↑, 3,   cl‑Casp3↑, 1,   cl‑Casp7↑, 1,   Cyt‑c↑, 1,   DR4↑, 1,   Myc↓, 1,   p27/CDKN1B↑, 1,   survivin↓, 1,   TumCD↑, 3,   YAP/TEAD↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,   other⇅, 1,   other↝, 2,   pRB↑, 1,   tumCV↓, 4,  

DNA Damage & Repair(tgid=10) ⓘ

DNMT3B↓, 1,   DNMTs↓, 1,   cl‑PARP↑, 1,   PCNA↓, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 2,   CDK4↓, 2,   cycD1/CCND1↓, 1,   cycE/CCNE↓, 1,   P21↓, 1,   TumCCA↑, 4,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD44↓, 2,   CSCs↓, 1,   CSCsMark↓, 1,   HDAC↓, 2,   HDAC2↓, 1,   HDAC8↓, 1,   IGFBP3↑, 1,   mTOR↓, 1,   PI3K↓, 3,   SOX2↓, 1,   TumCG↓, 11,   Wnt↓, 1,  

Migration(tgid=13) ⓘ

TumCI↓, 3,   TumCP↓, 11,   TumMeta↓, 2,   UroPA↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   EPR↝, 1,   HIF-1↓, 1,   VEGF↓, 5,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   COX2/PTGS2↓, 1,   Imm↑, 3,   Inflam↓, 1,   Inflam↑, 1,   NF-kB↓, 3,   T-Cell↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↑, 1,   CDK6↓, 1,   EstroRS/ERS↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↝, 1,   ChemoSen↑, 3,   Dose↝, 14,   eff↓, 2,   eff↑, 6,   eff∅, 1,   MDR1↑, 1,   selectivity↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

AR↑, 1,   BloodF↓, 1,   EstroRS/ERS↑, 1,   GutMicro↑, 9,   Myc↓, 1,   NOS2↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiCan⇅, 2,   antiNeop↑, 5,   AntiTum↑, 5,   cardioP↑, 1,   chemoP↑, 1,   chemoPv↑, 2,   OS↑, 4,   Risk↓, 6,   toxicity↓, 2,   TumVol↓, 1,   TumW↓, 2,   Weight↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

CD8+↑, 1,  
Total Targets: 108

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AcOH↑, 2,   Buty↑, 3,   NA↝, 1,   PA↑, 2,   SCFAs↑, 3,   SCFAs∅, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   ROS?, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,   other↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   Inflam↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 2,   BioEnh↑, 1,   Dose↝, 3,  

Clinical Biomarkers(tgid=22) ⓘ

GutMicro↑, 3,   GutMicro∅, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiTum↑, 1,   cardioP↑, 1,   chemoP↑, 1,   chemoPv↑, 1,   cognitive↑, 1,   neuroP↑, 1,   toxicity↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

CD8+↑, 1,  
Total Targets: 26

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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