Database Query Results : , , CD69

CD69, CD69: Click to Expand ⟱

Source:

Type:

CD69 is traditionally known as an early activation marker on T cells, natural killer (NK) cells, and other leukocytes.
Elevated CD69 expression on tumor-infiltrating lymphocytes (TILs) may reflect an ongoing anti-tumor immune response.

CD69 is an early lymphocyte activation marker that plays multifaceted roles in the tumor microenvironment, influencing cell retention, activation, and antitumor immune responses. In various cancers—including melanoma, breast cancer, NSCLC, HNSCC, and hematologic malignancies—the expression of CD69 on tumor-infiltrating immune cells often correlates with an active antitumor response and, in many cases, improved patient prognosis.

Scientific Papers found: Click to Expand⟱

1164-

PI,

Inhibition of T cell activation by the phytochemical piperine

in-vitro,

Nor,

*other↓, *CD25+↓, *IFN-γ↓, *IL2↓, *IL4↓, *IL17↓, *CD69↓, *CTLA-4↓, *p‑ERK↓, *IKKα↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Total Targets: 0

Pathway results for Effect on Normal Cells:

Transcription & Epigenetics ⓘ

other↓, 1,

Proliferation, Differentiation & Cell State ⓘ

p‑ERK↓, 1,

Immune & Inflammatory Signaling ⓘ

CD25+↓, 1, CD69↓, 1, CTLA-4↓, 1, IFN-γ↓, 1, IKKα↓, 1, IL17↓, 1, IL2↓, 1, IL4↓, 1,
Total Targets: 10

Scientific Paper Hit Count for: CD69, CD69

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells