Database Query Results : , , MIP-1β

MIP-1β, Macrophage Inflammatory Protein‐1β: Click to Expand ⟱
Source:
Type:
Macrophage Inflammatory Protein‐1β (MIP-1β), also known as CCL4, is a chemokine involved in recruiting and activating various immune cells such as monocytes, T lymphocytes, and natural killer (NK) cells within the tumor microenvironment. Its expression levels can influence immune cell infiltration and contribute to shaping the antitumor immune response.
– MIP-1β can be secreted by tumor-associated macrophages and other immune cells within the tumor microenvironment.
– Elevated levels are sometimes associated with improved immune surveillance.

• Dual Role: The role of MIP-1β in cancer is complex; while it promotes immune cell recruitment and may enhance antitumor immunity, in some conditions, chronic inflammation can facilitate tumor progression.
Scientific Papers found: Click to Expand⟱
1432- SFN,    Evaluation of biodistribution of sulforaphane after administration of oral broccoli sprout extract in melanoma patients with multiple atypical nevi
- Human, Melanoma, NA
other↑, decorin↑, *toxicity↓, IP-10/CXCL-10↓, MCP1↓, CXCL9↓, MIP-1β↓, IFN-γ↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Transcription & Epigenetics ⓘ

other↑, 1,  

Migration ⓘ

decorin↑, 1,  

Immune & Inflammatory Signaling ⓘ

CXCL9↓, 1,   IFN-γ↓, 1,   IP-10/CXCL-10↓, 1,   MCP1↓, 1,   MIP-1β↓, 1,  
Total Targets: 7

Pathway results for Effect on Normal Cells:


Functional Outcomes ⓘ

toxicity↓, 1,  
Total Targets: 1

Scientific Paper Hit Count for: MIP-1β, Macrophage Inflammatory Protein‐1β
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1094  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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