Database Query Results : , , VDR

VDR, Vitamin D receptor: Click to Expand ⟱
Source:
Type:
Vitamin D receptor

- Higher VDR expression in breast tumors is associated with a better prognosis.
- In colorectal cancer, reduced VDR expression has been frequently linked to more advanced disease and poorer outcomes.
- VDR expression can inhibit prostate cancer cell growth by slowing proliferation and promoting differentiation.
Scientific Papers found: Click to Expand⟱
1496- SFN,  VitD3,    Association between histone deacetylase activity and vitamin D-dependent gene expressions in relation to sulforaphane in human colorectal cancer cells
- in-vitro, CRC, Caco-2
eff↑, VDR↑, CYP11A1↓, HDAC↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Proliferation, Differentiation & Cell State ⓘ

HDAC↓, 1,   VDR↑, 1,  

Hormonal & Nuclear Receptors ⓘ

CYP11A1↓, 1,  

Drug Metabolism & Resistance ⓘ

eff↑, 1,  
Total Targets: 4

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: VDR, Vitamin D receptor
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1111  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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