Database Query Results : , , BTG3

BTG3, B-cell translocation gene 3: Click to Expand ⟱
Source:
Type: tumor suppressor gene
BTG3 (B-cell translocation gene 3) is considered a tumor suppressor gene involved in cell cycle regulation, apoptosis, and differentiation.

-BTG3 belongs to the BTG/Tob family of anti-proliferative genes and plays a role in cell cycle regulation by inhibiting cell proliferation and promoting differentiation.

-Several studies have reported reduced expression or loss of BTG3 in different tumor types, including lung, breast, prostate, ovarian, and colorectal cancers.
-Low BTG3 levels have been correlated with higher tumor grade, increased metastasis, and advanced clinical stage.
Scientific Papers found: Click to Expand⟱
1504- GEN,    Epigenetic targets of bioactive dietary components for cancer prevention and therapy
- Review, NA, NA
DNMTs↓, P21↑, p16↑, ac‑H3↑, ac‑H4↑, TumCCA↑, Casp↑, Apoptosis↑, hTERT/TERT↓, BTG3↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

Apoptosis↑, 1,   BTG3↑, 1,   Casp↑, 1,   hTERT/TERT↓, 1,  

Transcription & Epigenetics ⓘ

ac‑H3↑, 1,   ac‑H4↑, 1,  

DNA Damage & Repair ⓘ

DNMTs↓, 1,   p16↑, 1,  

Cell Cycle & Senescence ⓘ

P21↑, 1,   TumCCA↑, 1,  

Clinical Biomarkers ⓘ

hTERT/TERT↓, 1,  
Total Targets: 11

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: BTG3, B-cell translocation gene 3
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1115  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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