Database Query Results : , , miR-215-5p

miR-215-5p, miR-215-5p: Click to Expand ⟱

Source:

Type:

– miRNA-215-5p can regulate multiple target genes involved in cell cycle control, apoptosis, migration, invasion, and differentiation.

– In some studies, decreased levels of miRNA-215-5p have been associated with aggressive tumor characteristics and poorer survival, suggesting a tumor-suppressive role in those contexts.
– Overexpression of miRNA-215-5p may correlate with treatment resistance or more aggressive disease, indicating that its prognostic impact can be cancer type–specific.

Scientific Papers found: Click to Expand⟱

1552-

Api,

Apigenin inhibits the growth of colorectal cancer through down-regulation of E2F1/3 by miRNA-215-5p

in-vitro,

CRC,

HCT116

Apoptosis↑, TumCP↓, miR-215-5p↑, TumCCA↑, E2Fs↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Cell Death ⓘ

Apoptosis↑, 1,

Cell Cycle & Senescence ⓘ

E2Fs↓, 1, TumCCA↑, 1,

Migration ⓘ

miR-215-5p↑, 1, TumCP↓, 1,
Total Targets: 5

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: miR-215-5p, miR-215-5p

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells