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| Type: |
| Complement Receptor Type 3 (CR‐3), also known as Mac-1 or integrin αMβ2 CR‐3 is mainly expressed on immune cells such as macrophages, neutrophils, and natural killer (NK) cells and plays a role in immune complex clearance, cell adhesion, and phagocytosis. – CR‐3 is critical in mediating phagocytosis, cytotoxicity, and the clearance of opsonized pathogens and cellular debris. – In the tumor microenvironment, CR‐3–expressing immune cells can contribute to both anti-tumor responses and, in some contexts, protumoral inflammation. – The expression or activation state of CR‐3 on tumor-associated immune cells has been studied as a potential marker of the immune microenvironment’s status. – In some reports, a higher presence or activation of CR‐3–positive immune cells correlates with more effective immune surveillance and better outcomes, suggesting an anti-tumor role. – Conversely, if CR‐3 engagement promotes a protumoral inflammatory milieu (for example, by favoring the accumulation of immunosuppressive or M2-type macrophages), then higher CR‐3 activity may be associated with poorer prognosis. |
| 1573- | MushReishi, | Ganoderma lucidum (Reishi mushroom) for cancer treatment |
| - | Review, | NA, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:1140 State#:% Dir#:%
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