Database Query Results : , , Ceru

Ceru, ceruloplasmin: Click to Expand ⟱
Source:
Type:
Ceruloplasmin is primarily known as a copper-binding glycoprotein with roles in iron metabolism and antioxidant defense.
• Ceruloplasmin functions in copper transport and exhibits oxidase activity, which can help moderate oxidative stress.
• Its role in iron metabolism may further influence cellular redox balance and inflammatory processes.

-In several cancer types (such as breast, lung, and colorectal cancers), elevated ceruloplasmin levels have been associated with more aggressive disease features and, in some studies, poorer prognosis.
Scientific Papers found: Click to Expand⟱
1976- EGCG,    Epigallocatechin-3-gallate exhibits anti-tumor effect by perturbing redox homeostasis, modulating the release of pro-inflammatory mediators and decreasing the invasiveness of glioblastoma cells
- in-vitro, GBM, U87MG
ROS↑, MMP↓, Casp3↑, Cyt‑c↑, Trx1↓, Ceru↓, IL6↓, IL8↓, MCP1↓, RANTES?, uPA↝, ROS↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Ceru↓, 1,   ROS↑, 2,   Trx1↓, 1,  

Mitochondria & Bioenergetics ⓘ

MMP↓, 1,  

Cell Death ⓘ

Casp3↑, 1,   Cyt‑c↑, 1,  

Migration ⓘ

uPA↝, 1,  

Immune & Inflammatory Signaling ⓘ

IL6↓, 1,   IL8↓, 1,   MCP1↓, 1,   RANTES?, 1,  

Clinical Biomarkers ⓘ

IL6↓, 1,  
Total Targets: 12

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: Ceru, ceruloplasmin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1220  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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