Database Query Results : , , CEBPB

CEBPB, CCAAT/enhancer‐binding protein beta: Click to Expand ⟱
Source:
Type:
CCAAT/enhancer‐binding protein beta (CEBPB)
CEBPB is a transcription factor that regulates genes involved in proliferation, differentiation, immune responses, and inflammation.

– In some contexts, high expression of CEBPB correlates with aggressive tumor behavior and poor clinical outcomes, whereas in other settings it might indicate a more differentiated state and, consequently, a less aggressive phenotype.
- CEBPB expression was obviously elevated in CRC patients, and was associated with poor survival.
Scientific Papers found: Click to Expand⟱
2877- HNK,    Targeting histone deacetylase-3 blocked epithelial-mesenchymal plasticity and metastatic dissemination in gastric cancer
- in-vitro, GC, AGS
HDAC3↓, NF-kB↓, CEBPB↓, ER Stress↑, EMT↓, Wnt↓, β-catenin/ZEB1↓,
2178- itraC,    Itraconazole inhibits tumor growth via CEBPB-mediated glycolysis in colorectal cancer
- in-vivo, CRC, HCT116
TumCG↓, Glycolysis↓, CEBPB?, ENO1↓, LDHA↓, PKM2↓, GAPDH↓, ECAR↓, OCR↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Mitochondria & Bioenergetics ⓘ

OCR↓, 1,  

Core Metabolism/Glycolysis ⓘ

ECAR↓, 1,   ENO1↓, 1,   GAPDH↓, 1,   Glycolysis↓, 1,   LDHA↓, 1,   PKM2↓, 1,  

Protein Folding & ER Stress ⓘ

ER Stress↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

CEBPB?, 1,   CEBPB↓, 1,   EMT↓, 1,   HDAC3↓, 1,   TumCG↓, 1,   Wnt↓, 1,  

Migration ⓘ

β-catenin/ZEB1↓, 1,  

Immune & Inflammatory Signaling ⓘ

NF-kB↓, 1,  
Total Targets: 16

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: CEBPB, CCAAT/enhancer‐binding protein beta
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1259  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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