Database Query Results : , , DLEU1

DLEU1, Deleted in Lymphocytic Leukemia 1: Click to Expand ⟱
Source:
Type: oncogenic lncRNA
DLEU1 (Deleted in Lymphocytic Leukemia 1)
-In many studies, higher levels of DLEU1 expression have been associated with increased tumor aggressiveness and poorer clinical outcomes.
Scientific Papers found: Click to Expand⟱
2199- SK,    Induction of Ferroptosis by Shikonin in Gastric Cancer via the DLEU1/mTOR/GPX4 Axis
- in-vitro, GC, NA
ROS↑, lipid-P↑, Iron↑, MDA↑, GPx4↓, Ferritin↓, DLEU1↓, mTOR↓, Ferroptosis↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Ferroptosis↑, 1,   GPx4↓, 1,   Iron↑, 1,   lipid-P↑, 1,   MDA↑, 1,   ROS↑, 1,  

Metal & Cofactor Biology ⓘ

Ferritin↓, 1,  

Cell Death ⓘ

Ferroptosis↑, 1,  

Transcription & Epigenetics ⓘ

DLEU1↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

mTOR↓, 1,  

Clinical Biomarkers ⓘ

Ferritin↓, 1,  
Total Targets: 11

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: DLEU1, Deleted in Lymphocytic Leukemia 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1261  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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