Database Query Results : , , CYP2C6

CYP2C6, CYP2C6: Click to Expand ⟱
Source:
Type:
CYP2C6 belongs to the cytochrome P450 family of enzymes, which are primarily involved in the metabolism of both endogenous and exogenous compounds—including drugs and potential carcinogens.

-More than 95% of drugs and natural products are metabolized by CYPs, of which CYP1A, CYP2C, CYP2D, and CYP3A are the most important.
Scientific Papers found: Click to Expand⟱
2216- SK,    Shikonin upregulates the expression of drug-metabolizing enzymes and drug transporters in primary rat hepatocytes
- in-vivo, Nor, NA
*NRF2↑, *AhR↑, *CYP1A1↑, *CYP1A2↑, *CYP2C6↑, *CYP2D1↑, *CYP3A2↑, *NQO1↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

CYP1A1↑, 1,   NQO1↑, 1,   NRF2↑, 1,  

Core Metabolism/Glycolysis ⓘ

CYP2C6↑, 1,   CYP3A2↑, 1,  

Cell Death ⓘ

AhR↑, 1,  

Migration ⓘ

CYP2D1↑, 1,  

Drug Metabolism & Resistance ⓘ

CYP1A2↑, 1,  
Total Targets: 8

Scientific Paper Hit Count for: CYP2C6, CYP2C6
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1267  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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