Database Query Results : , , LPS

LPS, LPS: Click to Expand ⟱
Source:
Type:
Lipopolysaccharide (LPS) is not an endogenous protein or gene product produced by human cells, but rather a major component of the outer membrane of Gram-negative bacteria.
• LPS is a potent activator of the innate immune system through receptors such as Toll-like receptor 4 (TLR4).

• Its interaction with TLR4 on immune cells (e.g., macrophages, dendritic cells) and sometimes on tumor cells can trigger signaling cascades (e.g., NF-κB pathway) that result in the production of pro-inflammatory cytokines.
Scientific Papers found: Click to Expand⟱
2368- VitD3,    Vitamin D3 supplementation shapes the composition of gut microbiota and improves some obesity parameters induced by high-fat diet in mice
- in-vivo, Obesity, NA
*Weight↓, *TNF-α↓, *IL1β↓, LPS↓, *ZO-1↑, *GutMicro↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Immune & Inflammatory Signaling ⓘ

LPS↓, 1,  
Total Targets: 1

Pathway results for Effect on Normal Cells:


Migration ⓘ

ZO-1↑, 1,  

Immune & Inflammatory Signaling ⓘ

IL1β↓, 1,   TNF-α↓, 1,  

Clinical Biomarkers ⓘ

GutMicro↑, 1,  

Functional Outcomes ⓘ

Weight↓, 1,  
Total Targets: 5

Scientific Paper Hit Count for: LPS, LPS
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1299  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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