Database Query Results : , , KIF2C

KIF2C, Kinesin Family Member 2C: Click to Expand ⟱
Source:
Type:
KIF2C (Kinesin Family Member 2C), also known as Mitotic Centromere-Associated Kinesin (MCAK), is a microtubule-depolymerizing motor protein that plays an essential role in chromosome segregation during mitosis.

• Numerous studies have documented that KIF2C is frequently overexpressed in various tumor types, including breast, lung, colorectal, and hepatocellular carcinomas.

• Elevated expression levels are often observed in aggressive or advanced stages of cancers, reflecting its role in supporting the rapid proliferation of malignant cells.
Scientific Papers found: Click to Expand⟱
2405- SFN,    Sulforaphane Targets the TBX15/KIF2C Pathway to Repress Glycolysis and Cell Proliferation in Gastric Carcinoma Cells
- in-vitro, GC, SGC-7901 - in-vitro, GC, BGC-823
TumCP↓, Glycolysis↓, TBX15↑, GlucoseCon↓, lactateProd↓, tumCV↓, PKM2↓, KIF2C↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Mitochondria & Bioenergetics ⓘ

KIF2C↓, 1,  

Core Metabolism/Glycolysis ⓘ

GlucoseCon↓, 1,   Glycolysis↓, 1,   lactateProd↓, 1,   PKM2↓, 1,  

Transcription & Epigenetics ⓘ

tumCV↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

TBX15↑, 1,  

Migration ⓘ

TumCP↓, 1,  
Total Targets: 8

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: KIF2C, Kinesin Family Member 2C
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1304  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page