Database Query Results : , , RAAS

RAAS, Renin-Angiotensin-Aldosterone System: Click to Expand ⟱
Source:
Type:
The term RAAS stands for the Renin-Angiotensin-Aldosterone System, which is not a single molecule or factor but rather a hormonal cascade involved in regulating blood pressure, fluid, and electrolyte balance.


Components of RAAS:
-Renin: An enzyme produced by the kidneys that initiates the cascade.
-Angiotensinogen: A liver-produced precursor protein that renin converts into angiotensin I.
-Angiotensin-Converting Enzyme (ACE): Converts angiotensin I into angiotensin II, the active peptide.
-Angiotensin II: A potent vasoconstrictor that also stimulates the secretion of aldosterone.
-Aldosterone: A hormone produced by the adrenal glands that increases sodium and water retention.
Scientific Papers found: Click to Expand⟱
2657- AL,    Allicin pharmacology: Common molecular mechanisms against neuroinflammation and cardiovascular diseases
- Review, CardioV, NA - Review, AD, NA
*Inflam↓, *antiOx↑, *neuroP↑, *cardioP↑, *AntiTum↑, *mtDam↑, *HSP70/HSPA5↑, *NRF2↑, *RAAS↓, *cognitive↑, *SOD↑, *ROS↓, *NRF2↑, *ER Stress↓, *neuroP↑, *memory↑, *TBARS↓, *MPO↓, *SOD↑, *GSH↑, *iNOS↓, *p‑eNOS↑, *HO-1↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,   GSH↑, 1,   HO-1↑, 1,   MPO↓, 1,   NRF2↑, 2,   ROS↓, 1,   SOD↑, 2,   TBARS↓, 1,  

Mitochondria & Bioenergetics ⓘ

mtDam↑, 1,  

Cell Death ⓘ

iNOS↓, 1,  

Protein Folding & ER Stress ⓘ

ER Stress↓, 1,   HSP70/HSPA5↑, 1,  

Angiogenesis & Vasculature ⓘ

p‑eNOS↑, 1,  

Immune & Inflammatory Signaling ⓘ

Inflam↓, 1,  

Hormonal & Nuclear Receptors ⓘ

RAAS↓, 1,  

Functional Outcomes ⓘ

AntiTum↑, 1,   cardioP↑, 1,   cognitive↑, 1,   memory↑, 1,   neuroP↑, 2,  
Total Targets: 20

Scientific Paper Hit Count for: RAAS, Renin-Angiotensin-Aldosterone System
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1312  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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