Database Query Results : , , ACSL1

ACSL1, Acyl-CoA Synthetase Long-Chain Family Member 1: Click to Expand ⟱
Source:
Type:
ACSL1 (Acyl-CoA Synthetase Long-Chain Family Member 1) is an enzyme that plays a key role in lipid metabolism by converting free long‐chain fatty acids into fatty acyl-CoA esters.

– Some studies report that ACSL1 is upregulated, particularly in aggressive subtypes such as triple-negative breast cancer.

– Overexpression has been linked to enhanced cell proliferation and invasiveness.
Scientific Papers found: Click to Expand⟱
2740- BetA,    Effects and mechanisms of fatty acid metabolism-mediated glycolysis regulated by betulinic acid-loaded nanoliposomes in colorectal cancer
- in-vitro, CRC, HCT116
TumCP↓, Glycolysis↓, HK2↓, PFK1↓, PKM2↓, ACSL1↓, CPT1A↓, FASN↓, FAO↓, GlucoseCon↓, lactateProd↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis ⓘ

ACSL1↓, 1,   CPT1A↓, 1,   FAO↓, 1,   FASN↓, 1,   GlucoseCon↓, 1,   Glycolysis↓, 1,   HK2↓, 1,   lactateProd↓, 1,   PFK1↓, 1,   PKM2↓, 1,  

Migration ⓘ

TumCP↓, 1,  
Total Targets: 11

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: ACSL1, Acyl-CoA Synthetase Long-Chain Family Member 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1328  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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