Database Query Results : , , NGF

NGF, Nerve Growth Factor: Click to Expand ⟱
Source:
Type:
Nerve Growth Factor (NGF) plays a crucial role in the development, maintenance, and survival of certain neurons. Its connection to Alzheimer’s disease (AD) has been well-studied, particularly because of its importance in cholinergic neurons of the basal forebrain, which are notably affected in AD.
-Loss of NGF signaling contributes to cholinergic deficits, a hallmark of AD pathology
Scientific Papers found: Click to Expand⟱
4265- CA,    Potential applications of nanomedicine for treating Parkinson's disease
- Review, Park, NA
*NRF2↑, *ARE↑, *neuroP↑, *motorD↑, *cognitive↑, *SOD↑, *GSR↑, *NGF↑, *BDNF↑,
3875- Carno,    Ionophore Ability of Carnosine and Its Trehalose Conjugate Assists Copper Signal in Triggering Brain-Derived Neurotrophic Factor and Vascular Endothelial Growth Factor Activation In Vitro
- in-vitro, AD, NA
*IronCh↑, *CREB↑, *BDNF↑, *NGF↑, *antiOx↑, *ROS↓,
4210- Hup,    A Synopsis of Multitarget Potential Therapeutic Effects of Huperzine A in Diverse Pathologies–Emphasis on Alzheimer’s Disease Pathogenesis
- Review, AD, NA
*neuroP↑, *AChE↓, *Ach↑, *memory↑, *NGF↑, *BDNF↑,
3745- MFrot,  MF,    The neurobiological foundation of effective repetitive transcranial magnetic brain stimulation in Alzheimer's disease
- Review, AD, NA
*neuroP↑, *ROS↓, *Inflam↓, *5HT↑, *cFos↑, *Aβ↓, *memory↑, *BDNF↑, *Ach↑, *AChE↓, *cognitive↑, *BDNF↑, *NGF↑, *β-catenin/ZEB1↑, *p‑Akt↓, *mTOR↓, *MMP1↓, *MMP9↓, *MMP-10↓, *TIMP1↑, *TIMP2↑,
3814- mushLions,    Lion's Mane (Hericium erinaceus) Exerts Anxiolytic Effects in the rTg4510 Tau Mouse Model
- in-vitro, AD, NA
*neuroP↑, *cognitive↑, *cognitive∅, *BBB↑, *NGF↑, *BDNF↑, *NO↓, *memory↑, *Aβ↓,
3948- Shank,    Neuroprotective role of Convolvulus pluricaulis on aluminium induced neurotoxicity in rat brain
- in-vivo, AD, NA
*AChE↓, *ChAT↑, *NGF↑, *CDK5↓, *neuroP↑, *MDA↓,
4321- VitE,    Unraveling the molecular mechanisms of vitamin deficiency in Alzheimer's disease pathophysiology
- Review, AD, NA
*ROS↓, *cardioP↑, *lipid-P↓, *cognitive↑, *neuroP↑, *Aβ↓, *NGF↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 7

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,   ARE↑, 1,   GSR↑, 1,   lipid-P↓, 1,   MDA↓, 1,   NRF2↑, 1,   ROS↓, 3,   SOD↑, 1,  

Metal & Cofactor Biology ⓘ

IronCh↑, 1,  

Core Metabolism/Glycolysis ⓘ

CREB↑, 1,  

Cell Death ⓘ

p‑Akt↓, 1,  

Transcription & Epigenetics ⓘ

Ach↑, 2,  

Proliferation, Differentiation & Cell State ⓘ

cFos↑, 1,   mTOR↓, 1,  

Migration ⓘ

CDK5↓, 1,   MMP-10↓, 1,   MMP1↓, 1,   MMP9↓, 1,   TIMP1↑, 1,   TIMP2↑, 1,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature ⓘ

NO↓, 1,  

Barriers & Transport ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling ⓘ

Inflam↓, 1,  

Synaptic & Neurotransmission ⓘ

5HT↑, 1,   AChE↓, 3,   BDNF↑, 6,   ChAT↑, 1,   NGF↑, 7,  

Protein Aggregation ⓘ

Aβ↓, 3,  

Functional Outcomes ⓘ

cardioP↑, 1,   cognitive↑, 4,   cognitive∅, 1,   memory↑, 3,   motorD↑, 1,   neuroP↑, 6,  
Total Targets: 36

Scientific Paper Hit Count for: NGF, Nerve Growth Factor
1 Carnosic acid
1 Carnosine
1 Huperzine A/Huperzia serrata
1 Magnetic Field Rotating
1 Magnetic Fields
1 Mushroom Lion’s Mane
1 Shankhpushpi
1 Vitamin E
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1360  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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