Database Query Results : , , miR-485

miR-485, miR-485: Click to Expand ⟱
Source:
Type:
miR-485 is a microRNA with strong tumor-suppressor activity in most cancer types
-Frequently downregulated in cancer tissues, CSCs, and metastatic lesions.
-miR-485 is a strong EMT-suppressing miRNA

When miR-485 levels fall:
-↑ ZEB1
-↑ Snail/Slug
-↑ N-cadherin
-↑ Vimentin
-↑ invasion/metastasis
Scientific Papers found: Click to Expand⟱
4684- EGCG,    EGCG inhibits CSC-like properties through targeting miR-485/CD44 axis in A549-cisplatin resistant cells
- in-vivo, NSCLC, A549
miR-485↑, CSCs↓, CD44↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Proliferation, Differentiation & Cell State ⓘ

CD44↓, 1,   CSCs↓, 1,  

Migration ⓘ

miR-485↑, 1,  
Total Targets: 3

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: miR-485, miR-485
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1391  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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