Database Query Results : , , miR-429

miR-429, miR-429: Click to Expand ⟱
Source:
Type:
miR-429 is a key member of the miR-200 family (miR-200a/b/c, miR-141, miR-429) and plays a central role in epithelial–mesenchymal transition (EMT), metastasis, cancer stemness, and therapy response.
Across most solid tumors, miR-429 acts as a tumor-suppressor miRNA
-miR-429 is one of the strongest EMT-suppressing miRNAs.

✔ directly represses ZEB1/ZEB2
✔ maintains E-cadherin expression
✔ blocks EMT and metastasis
✔ suppresses CSC traits
✔ improves therapy response
Scientific Papers found: Click to Expand⟱
4707- CUR,    The Potential Role of Curcumin as a Regulator of microRNA in Colorectal Cancer: A Systematic Review
- Review, Var, NA
miR-497↑, miR-200c↑, miR-409-3p↑, miR-34a↑, miR-126↑, miR-145↑, miR-206↑, miR-491↑, miR-141↑, miR-429↑, miR-101↑, miR-15↑, miR-21↓, miR-155↓, miR-221↓, miR‐222↓, miR-17↓, miR-130a↓, miR-27a-3p↓, miR-20↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

miR-497↑, 1,  

Transcription & Epigenetics ⓘ

miR-145↑, 1,   miR-21↓, 1,   miR-27a-3p↓, 1,   miR-409-3p↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

miR-101↑, 1,   miR-34a↑, 1,   miR-429↑, 1,  

Migration ⓘ

miR-130a↓, 1,   miR-141↑, 1,   miR-155↓, 1,   miR-20↓, 1,   miR-200c↑, 1,   miR-206↑, 1,   miR-221↓, 1,   miR-491↑, 1,   miR‐222↓, 1,  

Angiogenesis & Vasculature ⓘ

miR-126↑, 1,   miR-15↑, 1,   miR-17↓, 1,  
Total Targets: 20

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: miR-429, miR-429
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1395  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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