Database Query Results : , , DNMT3B
DNMT3B, Maintenance DNA Methyltransferase: Click to Expand ⟱
| Source: |
| Type: oncogenic |
DNMT3B
Often UPREGULATED (mainly solid tumors)
Effect
-Aberrant de novo methylation at non-physiologic loci
-Silencing of differentiation and tumor suppressor genes
-Reinforces epigenetic chaos rather than orderly programming
Classification
-Contextual oncogenic epigenetic amplifier
|
Scientific Papers found: Click to Expand⟱
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0
Pathway results for Effect on Cancer / Diseased Cells:
Total Targets: 0
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: DNMT3B, Maintenance DNA Methyltransferase
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:1409 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid
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