Database Query Results : , , HOXB-AS1

HOXB-AS1, HOXB cluster antisense RNA 1: Click to Expand ⟱
Source:
Type:
HOXB-AS1 (HOXB cluster antisense RNA 1) is a long non-coding RNA (lncRNA) transcribed from the HOXB genomic locus. It does not encode a protein but exerts regulatory control at transcriptional, post-transcriptional, and epigenetic levels. Accumulating evidence places HOXB-AS1 as a pro-oncogenic lncRNA in multiple solid and hematologic malignancies.
-Generally upregulated in tumors compared with adjacent normal tissue.
Scientific Papers found: Click to Expand⟱
5080- SSE,    Sodium Selenite Regulates the Proliferation and Apoptosis of Gastric Cancer Cells by Suppressing the Expression of LncRNA HOXB-AS1
- in-vitro, GC, HGC27 - in-vitro, GC, NCI-N87
AntiTum↑, HOXB-AS1↓, TumCP↓, TumCI↓, Apoptosis↑, BAD↓, Bcl-2↓, cl‑Casp3↑, MMP2↓, E-cadherin↑, N-cadherin↓, ROS↑, NF-kB↓,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

ROS↑, 1,  

Cell Death ⓘ

Apoptosis↑, 1,   BAD↓, 1,   Bcl-2↓, 1,   cl‑Casp3↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

HOXB-AS1↓, 1,  

Migration ⓘ

E-cadherin↑, 1,   MMP2↓, 1,   N-cadherin↓, 1,   TumCI↓, 1,   TumCP↓, 1,  

Immune & Inflammatory Signaling ⓘ

NF-kB↓, 1,  

Functional Outcomes ⓘ

AntiTum↑, 1,  
Total Targets: 13

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: HOXB-AS1, HOXB cluster antisense RNA 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1427  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page