Database Query Results : , , NP/CIPN

NP/CIPN, neuropathy: Click to Expand ⟱
Source:
Type:

Chemotherapy-induced peripheral neuropathy (CIPN) is a common and disabling adverse effect of some widely used anticancer agents, including taxanes, vinca alkaloids, platinum salts, epothilones, and thalidomide.



Scientific Papers found: Click to Expand⟱
5323- ALC,    Preventive Effect of Acetyl-L-carnitine on Oxaliplatin-induced Peripheral Neuropathy
- Trial, Var, NA
Pain↓, NP/CIPN↓,
5321- ALC,    L-Carnitine
- Review, Var, NA
fatigue↝, *Dose↝, NP/CIPN↓,
5315- ALC,    Randomized Double-Blind Placebo-Controlled Trial of Acetyl-L-Carnitine for the Prevention of Taxane-Induced Neuropathy in Women Undergoing Adjuvant Breast Cancer Therapy
- Trial, BC, NA
other↑, NP/CIPN↑,
5316- ALC,    Two-Year Trends of Taxane-Induced Neuropathy in Women Enrolled in a Randomized Trial of Acetyl-L-Carnitine
- Trial, BC, NA
NP/CIPN↑,

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned

fatigue↝, 1,   NP/CIPN↓, 2,   NP/CIPN↑, 2,  

Transcription & Epigenetics

other↑, 1,  

Functional Outcomes

Pain↓, 1,  
Total Targets: 5

Pathway results for Effect on Normal Cells:


Drug Metabolism & Resistance

Dose↝, 1,  
Total Targets: 1

Scientific Paper Hit Count for: NP/CIPN, neuropathy
4 Acetyl-l-carnitine
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1438  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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