Database Query Results : , , KDM5C

KDM5C, lysine (K)-specific demethylase 5C: Click to Expand ⟱
Source: CGL-Driver Genes
Type: TSG
KDM5C (Lysine Demethylase 5C) is a member of the KDM5 family of histone demethylases, which are enzymes that play a crucial role in the regulation of gene expression by removing methyl groups from lysine residues on histone proteins.
KDM5C has been suggested to function as a tumor suppressor in certain types of cancer. Its loss or downregulation can lead to increased cell proliferation and tumorigenesis. For example, studies have shown that KDM5C can inhibit the expression of oncogenes and promote the expression of tumor suppressor genes.
Inhibitors of KDM5C or modulators of its activity may offer new avenues for cancer treatment, particularly in cancers where KDM5C is found to be dysregulated.

In many cancers, KDM5C is down regulated, acts as a tumor suppressor, where its downregulation is associated with increased tumor growth, invasion, and poor prognosis. This is often due to its role in regulating gene expression related to cell cycle control and apoptosis.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: KDM5C, lysine (K)-specific demethylase 5C
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:170  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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