Database Query Results : , , MEN1

MEN1, multiple endocrine neoplasia I: Click to Expand ⟱
Source: CGL-Driver Genes
Type: TSG
MEN1, or Multiple Endocrine Neoplasia type 1, is a genetic disorder that affects the endocrine system and is characterized by the development of tumors in multiple endocrine glands. It is caused by mutations in the MEN1 gene, which is a tumor suppressor gene. The condition is also known as Wermer's syndrome.

Individuals with MEN1 are at an increased risk for several types of tumors. The MEN1 gene, which encodes the protein menin, plays a crucial role in various cellular processes, including cell proliferation, apoptosis, and gene regulation.
Loss of menin function due to mutations in the MEN1 gene can lead to uncontrolled cell proliferation and tumorigenesis.

MEN I is inherently protumorigenic due to the genetic predisposition conferred by mutations in the MEN1 gene. The loss of menin function leads to dysregulation of cell growth and proliferation, contributing to the development of endocrine tumors.
Scientific Papers found: Click to Expand⟱

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 0

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: MEN1, multiple endocrine neoplasia I
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:185  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page